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The map label for this gene is mmgC [H]

Identifier: 78065380

GI number: 78065380

Start: 818404

End: 819591

Strand: Reverse

Name: mmgC [H]

Synonym: Bcep18194_A3906

Alternate gene names: 78065380

Gene position: 819591-818404 (Counterclockwise)

Preceding gene: 78065383

Following gene: 78065378

Centisome position: 22.19

GC content: 64.73

Gene sequence:

>1188_bases
ATGAGTGCTGCAACTTTTCATTGGGACGATCCGCTGCTGCTCAACCAGCAACTGACCGAAGAAGAGCGGATGGTGCGCGA
TGCCGCGCAGGCGTACGCGCAGGACAAGCTCGCACCGCGCGTGACCGAAGCGTTCCGCCACGAGCGCACCGACGCCGAAA
TCTTCCGGGAGATGGGCGAAGTCGGCCTGCTCGGCCCGACGATTCCCGAGGAATACGGCGGCCCCGGCCTCAATTACGTA
AGCTACGGCCTGATCGCCCGCGAAGTCGAGCGCGTCGACTCGGGCTACCGGTCGATGATGTCCGTGCAGTCGTCGCTCGT
GATGGTCCCGATCTACGAATTCGGCTCCGACGCGCAGAAGCAGAAATACCTGCCGAAGCTCGCCACCGGCGAATGGATCG
GCTGCTTCGGGCTGACCGAACCGAACCACGGCTCCGATCCGGGCAGCATGGTCACCCGCGCGAAGAAAGTGCCCGGCGGC
TACTCGCTGTCCGGCGCGAAGATGTGGATCACGAACTCGCCGATCGCCGACGTGTTCGTCGTATGGGCGAAGCTCGAAGA
GAACGGCAAGGACGCGATCCGCGGCTTCATCCTCGAGAAAGGCTGGAAGGGCCTGTCGGCACCGGCGATCCACGGCAAGG
TCGGGCTGCGCGCATCGATCACCGGCGAGATCGTCCTCGACGAAGTGTTCGTTCCGGAAGAGAACCTGATGCCGAACGTG
AGCGGCCTGCGCGGCCCGTTCACATGCCTGAACTCGGCGCGCTACGGGATCGCATGGGGCGCACTCGGTGCCGCCGAATC
CTGCTGGCACACCGCGCGCCAGTACGTGCTCGATCGCCAGCAGTTCGGCCGGCCGCTCGCCGCGAACCAGCTGATCCAGA
AGAAGCTCGCCGACATGCAGACCGAAATCACACTCGGCCTGCAAGGCGTGCTGCGCCTCGGCCGGATGAAGGACGAAGGC
ACGGCGGCTGTCGAGATCACGTCGATCATGAAGCGCAATTCGTGCGGCAAGTCGCTCGACATCGCGCGGCTCGCGCGCGA
CATGCTCGGCGGCAACGGTATCTCCGACGAATTCGGCGTCGCACGCCACCTCGTGAATCTCGAAGTGGTCAACACGTACG
AAGGCACGCACGACATCCACGCGCTGATCCTCGGCCGCGCGCAGACCGGCATCCAGGCCTTCTTCTGA

Upstream 100 bases:

>100_bases
GGGCCCGAGTAAGCGCTGAAGTGCTCACTCGGGTCGACCGCAAAGCATGGGACCCGAGTAAGCGCTAAAGCGCTAACTCG
GGTCGACAGGAGATGAGACG

Downstream 100 bases:

>100_bases
TCGTCCGGATGCGGAAAGCGCGGCCGCCACGCCGCGCGCGCGTTCGCGCAAAAGACACGGCCCGCCCGGCATGACTGCCG
GGCGGGCCGTTTTTCATCTG

Product: Acyl-CoA dehydrogenase-like

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSAATFHWDDPLLLNQQLTEEERMVRDAAQAYAQDKLAPRVTEAFRHERTDAEIFREMGEVGLLGPTIPEEYGGPGLNYV
SYGLIAREVERVDSGYRSMMSVQSSLVMVPIYEFGSDAQKQKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGG
YSLSGAKMWITNSPIADVFVVWAKLEENGKDAIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENLMPNV
SGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRQQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEG
TAAVEITSIMKRNSCGKSLDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF

Sequences:

>Translated_395_residues
MSAATFHWDDPLLLNQQLTEEERMVRDAAQAYAQDKLAPRVTEAFRHERTDAEIFREMGEVGLLGPTIPEEYGGPGLNYV
SYGLIAREVERVDSGYRSMMSVQSSLVMVPIYEFGSDAQKQKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGG
YSLSGAKMWITNSPIADVFVVWAKLEENGKDAIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENLMPNV
SGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRQQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEG
TAAVEITSIMKRNSCGKSLDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
>Mature_394_residues
SAATFHWDDPLLLNQQLTEEERMVRDAAQAYAQDKLAPRVTEAFRHERTDAEIFREMGEVGLLGPTIPEEYGGPGLNYVS
YGLIAREVERVDSGYRSMMSVQSSLVMVPIYEFGSDAQKQKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGGY
SLSGAKMWITNSPIADVFVVWAKLEENGKDAIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENLMPNVS
GLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRQQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEGT
AAVEITSIMKRNSCGKSLDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=395, Percent_Identity=66.0759493670886, Blast_Score=527, Evalue=1e-150,
Organism=Homo sapiens, GI7669494, Length=375, Percent_Identity=64.5333333333333, Blast_Score=489, Evalue=1e-138,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=33.2446808510638, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=33.4302325581395, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=31.1827956989247, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI4501859, Length=367, Percent_Identity=29.1553133514986, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=31.5104166666667, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=31.5104166666667, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI187960098, Length=401, Percent_Identity=29.426433915212, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI4557231, Length=401, Percent_Identity=29.426433915212, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI21361497, Length=350, Percent_Identity=31.7142857142857, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=28.4574468085106, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=27.7777777777778, Blast_Score=132, Evalue=5e-31,
Organism=Escherichia coli, GI87081958, Length=350, Percent_Identity=27.4285714285714, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786223, Length=373, Percent_Identity=24.6648793565684, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17534353, Length=394, Percent_Identity=63.1979695431472, Blast_Score=512, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17508101, Length=376, Percent_Identity=32.7127659574468, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=32.620320855615, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=30.4109589041096, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17569725, Length=375, Percent_Identity=30.1333333333333, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71985184, Length=370, Percent_Identity=31.3513513513514, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=35.036496350365, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=28.7234042553192, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71985192, Length=280, Percent_Identity=33.2142857142857, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=27.4406332453826, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=31.1355311355311, Blast_Score=140, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17533517, Length=372, Percent_Identity=24.7311827956989, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17551932, Length=378, Percent_Identity=24.8677248677249, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=25.3333333333333, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17531909, Length=233, Percent_Identity=27.4678111587983, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19920834, Length=397, Percent_Identity=62.72040302267, Blast_Score=491, Evalue=1e-139,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=32.4324324324324, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=32.5268817204301, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24666513, Length=365, Percent_Identity=31.5068493150685, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=30.9333333333333, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI281363737, Length=408, Percent_Identity=29.9019607843137, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=30.1587301587302, Blast_Score=161, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43306; Mature: 43175

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAATFHWDDPLLLNQQLTEEERMVRDAAQAYAQDKLAPRVTEAFRHERTDAEIFREMGE
CCCCEECCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCC
VGLLGPTIPEEYGGPGLNYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIYEFGSDAQK
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHCCCCHHH
QKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGGYSLSGAKMWITNSPIADVFV
HHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHH
VWAKLEENGKDAIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENLMPNV
HHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCC
SGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRQQFGRPLAANQLIQKKLADMQ
CCCCCHHHHHCCCCCCEEHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKSLDIARLARDMLGGNGISDEFGV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHH
ARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
HHHHHEEEEEECCCCCHHHHHHEEHHHHCCHHHCC
>Mature Secondary Structure 
SAATFHWDDPLLLNQQLTEEERMVRDAAQAYAQDKLAPRVTEAFRHERTDAEIFREMGE
CCCEECCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCC
VGLLGPTIPEEYGGPGLNYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIYEFGSDAQK
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHCCCCHHH
QKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGGYSLSGAKMWITNSPIADVFV
HHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHH
VWAKLEENGKDAIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENLMPNV
HHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCC
SGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRQQFGRPLAANQLIQKKLADMQ
CCCCCHHHHHCCCCCCEEHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKSLDIARLARDMLGGNGISDEFGV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHH
ARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
HHHHHEEEEEECCCCCHHHHHHEEHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]