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The map label for this gene is thiL [H]

Identifier: 78065188

GI number: 78065188

Start: 600222

End: 601220

Strand: Reverse

Name: thiL [H]

Synonym: Bcep18194_A3712

Alternate gene names: 78065188

Gene position: 601220-600222 (Counterclockwise)

Preceding gene: 229260091

Following gene: 78065187

Centisome position: 16.28

GC content: 72.67

Gene sequence:

>999_bases
GTGCCAGCCGCCCTCTCCGAGTTTTCGCTGATCGAACGCTTCTTCACGCGCCGCGCCGCGCAGGGCGCCCGTACGTCGAC
ACTCGGCATCGGCGACGATTGCGCGTTGATCACGCCCCGATCCGGGAAATTGCTGGCCATTTCGACCGACATGCTGGTGG
AAGGCCGCCACTTCTTCCCCGACGTCGCGCCCGACGCGCTCGGCCACAAGACGCTCGCGGTCAACCTGTCCGACCTCGCG
GCGATGGGTGCCGAGCCGCGCGCGTTCACGCTCGCGTGCGCGCTGCCGCGGGCCGACGCCGCGTGGCTGGAAGCGTTCAG
CAACGGGCTGTTCGCGCTCGCCGAGCGCTACGGCTGCGAGCTGATCGGTGGCGACACGACGAGCGGCCCGCTGAACCTGT
GCGTGACCGTCTTCGGCGAAGTCTCACCCGACGCGGCACTGCGCCGCGATGCCGCGCGCGACGGCGACGACGTCTGGGTG
TCCGGCACGCTCGGCGATGCACGCGCCGGCCTCGGTGTCGCGCGTGGCGAATGGGCGGCCGGCGCAGACGAAGCAGCCGC
GTTCCGGCGTGCGCTCGAGCGCCCCGAACCGCGCATCGCGCTCGGCCTCGGGCTCGCGGGCGTCGCGCACGCGGCGCTCG
ATATCTCGGACGGCCTCGCCGGCGACCTGCAGCACATCCTGGCCCGCTCGAACGTGCGTGCCGAAATCGATGCCGACGCG
GTGCCGCGCTCGGCCGCGCTCGCGACGCTGCCACCCGACGTGCAGCGCCGCTGCACGCTGGCCGGCGGCGACGACTACGA
ACTGTGCTTCACCGCGCCGGCGGCGGCCCGCGCGGCGGTCGAAGCAGCCGGCGTAACGGCCGGCGTGGCGGTCACGCGAA
TCGGTACAATACGCGCGTTGTCCGCGCCGTCGGAGCAGCCCGCGATCGCGTGGCGCGACGCCGCCGGCGCGCCTCTCGCT
CTCACGTTGCACGGCTTCGATCACTTCCATGCAGACTGA

Upstream 100 bases:

>100_bases
CGGGTGCAACAGCCGCGACAAAATTGTACTGAACGGTGCAGGAACGCCGCCGTTCGCCTCGTACAATGCCGTTCCTTCCA
ACGTTTCGGATCCATCCGCC

Downstream 100 bases:

>100_bases
CCCGACGCCCGCGCACGCCGCGGCCGAGCCCGGCGCCGCATCCGGCGGCAACGCGCCGCCGCGCGCGACCGCGCGCTTCA
TGCTGTCGCACCCGGCGCAC

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPAALSEFSLIERFFTRRAAQGARTSTLGIGDDCALITPRSGKLLAISTDMLVEGRHFFPDVAPDALGHKTLAVNLSDLA
AMGAEPRAFTLACALPRADAAWLEAFSNGLFALAERYGCELIGGDTTSGPLNLCVTVFGEVSPDAALRRDAARDGDDVWV
SGTLGDARAGLGVARGEWAAGADEAAAFRRALERPEPRIALGLGLAGVAHAALDISDGLAGDLQHILARSNVRAEIDADA
VPRSAALATLPPDVQRRCTLAGGDDYELCFTAPAAARAAVEAAGVTAGVAVTRIGTIRALSAPSEQPAIAWRDAAGAPLA
LTLHGFDHFHAD

Sequences:

>Translated_332_residues
MPAALSEFSLIERFFTRRAAQGARTSTLGIGDDCALITPRSGKLLAISTDMLVEGRHFFPDVAPDALGHKTLAVNLSDLA
AMGAEPRAFTLACALPRADAAWLEAFSNGLFALAERYGCELIGGDTTSGPLNLCVTVFGEVSPDAALRRDAARDGDDVWV
SGTLGDARAGLGVARGEWAAGADEAAAFRRALERPEPRIALGLGLAGVAHAALDISDGLAGDLQHILARSNVRAEIDADA
VPRSAALATLPPDVQRRCTLAGGDDYELCFTAPAAARAAVEAAGVTAGVAVTRIGTIRALSAPSEQPAIAWRDAAGAPLA
LTLHGFDHFHAD
>Mature_331_residues
PAALSEFSLIERFFTRRAAQGARTSTLGIGDDCALITPRSGKLLAISTDMLVEGRHFFPDVAPDALGHKTLAVNLSDLAA
MGAEPRAFTLACALPRADAAWLEAFSNGLFALAERYGCELIGGDTTSGPLNLCVTVFGEVSPDAALRRDAARDGDDVWVS
GTLGDARAGLGVARGEWAAGADEAAAFRRALERPEPRIALGLGLAGVAHAALDISDGLAGDLQHILARSNVRAEIDADAV
PRSAALATLPPDVQRRCTLAGGDDYELCFTAPAAARAAVEAAGVTAGVAVTRIGTIRALSAPSEQPAIAWRDAAGAPLAL
TLHGFDHFHAD

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=330, Percent_Identity=46.3636363636364, Blast_Score=242, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34326; Mature: 34195

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAALSEFSLIERFFTRRAAQGARTSTLGIGDDCALITPRSGKLLAISTDMLVEGRHFFP
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEECCEEECCCCCCC
DVAPDALGHKTLAVNLSDLAAMGAEPRAFTLACALPRADAAWLEAFSNGLFALAERYGCE
CCCCHHCCCCEEEEEHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCHHHHHHHHCCE
LIGGDTTSGPLNLCVTVFGEVSPDAALRRDAARDGDDVWVSGTLGDARAGLGVARGEWAA
EECCCCCCCHHEEEEEEECCCCCCHHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCCCCC
GADEAAAFRRALERPEPRIALGLGLAGVAHAALDISDGLAGDLQHILARSNVRAEIDADA
CCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEECCCC
VPRSAALATLPPDVQRRCTLAGGDDYELCFTAPAAARAAVEAAGVTAGVAVTRIGTIRAL
CCCCCEEECCCCCHHHEEEECCCCCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHHEEEE
SAPSEQPAIAWRDAAGAPLALTLHGFDHFHAD
CCCCCCCCEEEECCCCCCEEEEEECCHHCCCC
>Mature Secondary Structure 
PAALSEFSLIERFFTRRAAQGARTSTLGIGDDCALITPRSGKLLAISTDMLVEGRHFFP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEECCEEECCCCCCC
DVAPDALGHKTLAVNLSDLAAMGAEPRAFTLACALPRADAAWLEAFSNGLFALAERYGCE
CCCCHHCCCCEEEEEHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCHHHHHHHHCCE
LIGGDTTSGPLNLCVTVFGEVSPDAALRRDAARDGDDVWVSGTLGDARAGLGVARGEWAA
EECCCCCCCHHEEEEEEECCCCCCHHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCCCCC
GADEAAAFRRALERPEPRIALGLGLAGVAHAALDISDGLAGDLQHILARSNVRAEIDADA
CCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEECCCC
VPRSAALATLPPDVQRRCTLAGGDDYELCFTAPAAARAAVEAAGVTAGVAVTRIGTIRAL
CCCCCEEECCCCCHHHEEEECCCCCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHHEEEE
SAPSEQPAIAWRDAAGAPLALTLHGFDHFHAD
CCCCCCCCEEEECCCCCCEEEEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]