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The map label for this gene is mraW

Identifier: 78065113

GI number: 78065113

Start: 520062

End: 521003

Strand: Direct

Name: mraW

Synonym: Bcep18194_A3637

Alternate gene names: 78065113

Gene position: 520062-521003 (Clockwise)

Preceding gene: 78065112

Following gene: 78065114

Centisome position: 14.08

GC content: 64.65

Gene sequence:

>942_bases
ATGGGAAACGAATTGCAGCATCGGACCGTGTTGTTGGACGAAGCGGTCGAATCGCTCGTGACGCGACCGGACGGCATTTA
TGTCGACGGCACGTTCGGGCGCGGCGGCCATAGCCGCGCGGTGCTCGCGCGGCTGGCGCCGGGCGGGCGGCTGATCGCGT
TCGACAAGGATCCGAGAGCGATCGAGACGGCGCAGGGCATCGAGGATGCGCGCTTTTCGATCGTGCATGACAGCTTTGCA
TCGATGCGCGACGCGCTTGCGGCGCGCGGCGTCGAGAAGGTGTCGGGTGTGTTGCTCGACCTGGGCGTGTCCTCGCCGCA
GGTGGACGATCCGGCGCGCGGCTTCAGCTTCCGCGCCGATGGTCCGCTGGACATGCGGATGGACCCGACGCGCGGCGAGT
CGGCGGCGGAATGGCTCGCACGGGCTTCGGTGCAGGAATTGACGGAGGTAATACGGGATTATGGGGAAGAACGGTTTGCT
TTTCAGATTGCAAAGGCGCTTGTTGCTCGCCGGGCAGAGTCCGACCGTCTTGGGCCTCTCGACACCACGGGCGAGCTTGC
CCAAATCGTGGGTCACGTCGTCAAAACCCGTGAGAAGGGCAAGGATCCGGCAACCCGCACCTTTCAGGCTATACGGATTC
ACGTCAATCAAGAGCTTGCGGACCTGCAAGTCGTACTAGACGCGGCACTGTCGTTGCTGGAGCAAGGGGGGCGGCTGGTG
GTCATCAGCTTTCATTCACTCGAGGACCGGATCGTCAAGCGATTCATGCAGGCGCACGCGAGTGCGCCTGCGGTCGATCG
TCGCCTGCCGATCCGCGCCGTCGACCTCCCGAGCCCGCCGCTCAAGATCATCAGCCGCCAGTTTCCGAGTGAAGCGGAAG
TCGCTGCGAATCCGCGCGCCCGCTCGGCCGTGATGCGCATCGCGGAGCGCGTCACGCCATGA

Upstream 100 bases:

>100_bases
CGCAAACCTACAACGCGAAGGAGCAGGCAGCGATGGCGCAGGGCATGCCCGACGCGCTGAAGAATTTCACGTTCTGATTG
CGGTGACGGAGACGCCCGCG

Downstream 100 bases:

>100_bases
GCCGCTTCAATATCTTCCTGCTGATCATCGTGATGGGTTGCGCGTTGTCGGTCGTCAATTCGACGAACCAGCAGCGCCAG
ATCTTCATCCAGCTGCAGCG

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MGNELQHRTVLLDEAVESLVTRPDGIYVDGTFGRGGHSRAVLARLAPGGRLIAFDKDPRAIETAQGIEDARFSIVHDSFA
SMRDALAARGVEKVSGVLLDLGVSSPQVDDPARGFSFRADGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFA
FQIAKALVARRAESDRLGPLDTTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIISRQFPSEAEVAANPRARSAVMRIAERVTP

Sequences:

>Translated_313_residues
MGNELQHRTVLLDEAVESLVTRPDGIYVDGTFGRGGHSRAVLARLAPGGRLIAFDKDPRAIETAQGIEDARFSIVHDSFA
SMRDALAARGVEKVSGVLLDLGVSSPQVDDPARGFSFRADGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFA
FQIAKALVARRAESDRLGPLDTTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIISRQFPSEAEVAANPRARSAVMRIAERVTP
>Mature_312_residues
GNELQHRTVLLDEAVESLVTRPDGIYVDGTFGRGGHSRAVLARLAPGGRLIAFDKDPRAIETAQGIEDARFSIVHDSFAS
MRDALAARGVEKVSGVLLDLGVSSPQVDDPARGFSFRADGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAF
QIAKALVARRAESDRLGPLDTTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLVV
ISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIISRQFPSEAEVAANPRARSAVMRIAERVTP

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=338, Percent_Identity=36.9822485207101, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI165377202, Length=198, Percent_Identity=37.8787878787879, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1786270, Length=316, Percent_Identity=53.7974683544304, Blast_Score=328, Evalue=2e-91,
Organism=Drosophila melanogaster, GI62472493, Length=335, Percent_Identity=37.3134328358209, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI28571637, Length=335, Percent_Identity=37.3134328358209, Blast_Score=177, Evalue=9e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 34190; Mature: 34059

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNELQHRTVLLDEAVESLVTRPDGIYVDGTFGRGGHSRAVLARLAPGGRLIAFDKDPRA
CCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHEECCCCEEEEECCCCCH
IETAQGIEDARFSIVHDSFASMRDALAARGVEKVSGVLLDLGVSSPQVDDPARGFSFRAD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKALVARRAESDRLGPL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCC
DTTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCEE
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIISRQFPSEAEVAANPRA
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCHHHCCCHH
RSAVMRIAERVTP
HHHHHHHHHHCCC
>Mature Secondary Structure 
GNELQHRTVLLDEAVESLVTRPDGIYVDGTFGRGGHSRAVLARLAPGGRLIAFDKDPRA
CCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHEECCCCEEEEECCCCCH
IETAQGIEDARFSIVHDSFASMRDALAARGVEKVSGVLLDLGVSSPQVDDPARGFSFRAD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKALVARRAESDRLGPL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCC
DTTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCEE
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIISRQFPSEAEVAANPRA
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCHHHCCCHH
RSAVMRIAERVTP
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA