Click here to switch to the map view.

The map label for this gene is rpe [H]

Identifier: 78065099

GI number: 78065099

Start: 497441

End: 498127

Strand: Reverse

Name: rpe [H]

Synonym: Bcep18194_A3623

Alternate gene names: 78065099

Gene position: 498127-497441 (Counterclockwise)

Preceding gene: 78065102

Following gene: 78065098

Centisome position: 13.48

GC content: 65.21

Gene sequence:

>687_bases
ATGACCCAATTCCGCATCGCTCCCAGCATCCTGTCGGCCGATTTCGCTCGGCTCGGCGAAGAAGTCCGTAACGTCGTCGC
CGCCGGCGCCGACTGGATCCACTTCGACGTGATGGACAACCATTATGTGCCGAACCTGACGATCGGCCCGCTCGTGTGCG
AAGCGATCCGCCCGCACGTGCAGGTGCCGATCGACGTGCACCTGATGGTGCGCCCGGTCGACCGGATCGTGCCCGATTTT
GCGAAAGCCGGTGCTAACCTGATCAGCTTCCACCCGGAAGGCTCCGATCACATCGACCGCACGCTGTCGCTGATCCGCGA
CCACGGCTGCAAGGCCGGCCTCGTGTTCAACCCGGCCACGCCGCTGAACTACCTCGACCACGTGATGGATCGTCTCGACT
TCGTGCTGCTGATGTCGGTCAACCCGGGCTTCGGCGGCCAGTCGTTCATTCCGGAAACGCTGAACAAGCTGCGCGAAGCA
CGTGCACGCATCGACGCGTACACGGAGCGCACCGGCCGCGAGATCCTGCTCGAGGTCGACGGCGGCGTGAAGACCGACAA
CATCGCGGAAATCGCAGCGGCCGGCGCCGACACCTTCGTCGCGGGTTCGGCCATCTTCGGCAAGCCCGACTACCGCACGG
TGATCGACGAGATGCGCGCCGCGCTCGCGACCGTCGAGCGGAGCTGA

Upstream 100 bases:

>100_bases
TATGCGCAATCGGGCCTCGACCGCACGGCCCGCCGCCGCGCACCGGGTCGCCGGACGGTAGAATGGCGGTTTTGCGCCGC
TACGTCCCCGCTCCCCTGCC

Downstream 100 bases:

>100_bases
CACCGTGGCCGAATCGTCGCTCGCCGGCCATGCGCCGGCCGGGGCCGCCACGGAAGCCGCCCCGATCCGCTTCGCCACGC
CGCGCATCGACGCGGCGCTG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTQFRIAPSILSADFARLGEEVRNVVAAGADWIHFDVMDNHYVPNLTIGPLVCEAIRPHVQVPIDVHLMVRPVDRIVPDF
AKAGANLISFHPEGSDHIDRTLSLIRDHGCKAGLVFNPATPLNYLDHVMDRLDFVLLMSVNPGFGGQSFIPETLNKLREA
RARIDAYTERTGREILLEVDGGVKTDNIAEIAAAGADTFVAGSAIFGKPDYRTVIDEMRAALATVERS

Sequences:

>Translated_228_residues
MTQFRIAPSILSADFARLGEEVRNVVAAGADWIHFDVMDNHYVPNLTIGPLVCEAIRPHVQVPIDVHLMVRPVDRIVPDF
AKAGANLISFHPEGSDHIDRTLSLIRDHGCKAGLVFNPATPLNYLDHVMDRLDFVLLMSVNPGFGGQSFIPETLNKLREA
RARIDAYTERTGREILLEVDGGVKTDNIAEIAAAGADTFVAGSAIFGKPDYRTVIDEMRAALATVERS
>Mature_227_residues
TQFRIAPSILSADFARLGEEVRNVVAAGADWIHFDVMDNHYVPNLTIGPLVCEAIRPHVQVPIDVHLMVRPVDRIVPDFA
KAGANLISFHPEGSDHIDRTLSLIRDHGCKAGLVFNPATPLNYLDHVMDRLDFVLLMSVNPGFGGQSFIPETLNKLREAR
ARIDAYTERTGREILLEVDGGVKTDNIAEIAAAGADTFVAGSAIFGKPDYRTVIDEMRAALATVERS

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=217, Percent_Identity=39.63133640553, Blast_Score=157, Evalue=7e-39,
Organism=Homo sapiens, GI219879828, Length=217, Percent_Identity=37.7880184331797, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI24307923, Length=172, Percent_Identity=32.5581395348837, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI1789788, Length=226, Percent_Identity=72.1238938053097, Blast_Score=338, Evalue=1e-94,
Organism=Escherichia coli, GI1790523, Length=230, Percent_Identity=36.9565217391304, Blast_Score=155, Evalue=1e-39,
Organism=Escherichia coli, GI1790754, Length=214, Percent_Identity=30.8411214953271, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=222, Percent_Identity=39.1891891891892, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322341, Length=241, Percent_Identity=36.9294605809129, Blast_Score=159, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24586301, Length=221, Percent_Identity=37.10407239819, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 25014; Mature: 24883

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQFRIAPSILSADFARLGEEVRNVVAAGADWIHFDVMDNHYVPNLTIGPLVCEAIRPHV
CCCEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCE
QVPIDVHLMVRPVDRIVPDFAKAGANLISFHPEGSDHIDRTLSLIRDHGCKAGLVFNPAT
ECCEEEEEEEECHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCC
PLNYLDHVMDRLDFVLLMSVNPGFGGQSFIPETLNKLREARARIDAYTERTGREILLEVD
HHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GGVKTDNIAEIAAAGADTFVAGSAIFGKPDYRTVIDEMRAALATVERS
CCCCCCHHHHHHHCCCCHHEECCEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQFRIAPSILSADFARLGEEVRNVVAAGADWIHFDVMDNHYVPNLTIGPLVCEAIRPHV
CCEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCE
QVPIDVHLMVRPVDRIVPDFAKAGANLISFHPEGSDHIDRTLSLIRDHGCKAGLVFNPAT
ECCEEEEEEEECHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCC
PLNYLDHVMDRLDFVLLMSVNPGFGGQSFIPETLNKLREARARIDAYTERTGREILLEVD
HHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GGVKTDNIAEIAAAGADTFVAGSAIFGKPDYRTVIDEMRAALATVERS
CCCCCCHHHHHHHCCCCHHEECCEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]