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The map label for this gene is dsbD [H]

Identifier: 78064953

GI number: 78064953

Start: 337044

End: 338897

Strand: Direct

Name: dsbD [H]

Synonym: Bcep18194_A3476

Alternate gene names: 78064953

Gene position: 337044-338897 (Clockwise)

Preceding gene: 78064952

Following gene: 78064956

Centisome position: 9.12

GC content: 68.88

Gene sequence:

>1854_bases
ATGTTTAACGGTATGGCGCTTCCCGTGCGCGTGCGCGCGCTGCGGTTCCTCGCAGTCCTGTTGTCGTTCATGCTCGTGCT
GGGCGGCCTGTCGGTCGCGCGCGCGGCCGACGATTTCCTCGATCCGTCGGTTGCGTTCAAGTTCAGTGCGAGCGAATCGC
CGGGACAGGTGGACGTCCGCTTCAAGGTCGCCAACGGCTACTACCTGTACCGCGAGCGGTTCGCGTTCGCGGTAAAGAGC
GGGCAGGCGACGCTTGGCGATCCGCAATTCCCGGCCGGCCACGTGAAGTTCGACCAGACGTTCCAGAAGAACGTCGAGAC
CTACCGTGACGAAGTCGTCGTGCACGTGCCCGTCAAGCAGGCGTCGGGCCCATTCGAGCTCGCGGTGACATCGCAGGGGT
GTGCGGACGAAGGCATCTGCTATCCGCCGGCCGAGCACGTCGTGAAGGTCGACGGCGCCGCGCTGGGTGCTGCTTCGTCA
CCGTCGTCCGGCGATGCGGCTGCCGCCGGCAGCTGGTTCGACAAGGTCACGAGCGCCGATTTCGCGCAGTCGCTGCTCGA
AGGGCACGGCTTCTTCACGATCGTCGCCCTGTATTTCGTCGCGGGCGTCGTGTTGAGCCTCCTTCCGTGCTCGTACCCGA
TGATCCCGATCGTGTCGGCGATCATCATCGGCCAGGGCACGCGGGCGACGCATGCGCGCGGCTTCGCGTTGTCGCTGACC
TACGTGGTCGGCATGGCGCTGGTCTATACGGTGCTCGGCATCGCCGCGGCGCTGGTCGGCCAGGGCCTCGGTGCGTGGCT
GCAGAACCCGTGGGTGCTCGGCGCGTTCGGCGTGCTGCTGACCGCGTTCGCCGTCTCGCTGATCTCGGGCAAGGACATCG
CGCTGCCCGCGCGCTGGCAGAACGGCGCAGCCGAGGCATCGGGCGCGCGCCAGGGCGGCCATTTCGTCGCGGTCGCGGCG
ATGGGCGCGCTGTCCGCGCTGGTCGTCGGCGCATGCATGACGGCGCCGCTGTTCGCGGTGCTCGCTTTCATTGCGCACAC
GGGCAATGCGCTGCTCGGCGGTGCCGCGCTGTTCGCGATGGGGCTGGGGCTGGGCGTGCCGCTGCTGGTCGTCGGCGTCG
GCGCCGGGACGGTGCTGCCGCGCGCCGGCGCATGGATGGACGGCGTGAAGGTGTTCTTCGGCATCGTGCTGCTCGCGGCC
GCGCTGTGGATCGTGTGGCCGGTGCTGGCCGGTGGCCTGAAGATGGTGCTCGCTGCGTTGTGGCTGCTGATCGCGGCCGC
GGCGCTCGGGCTGTTCACGCCGAATGCCGGCGCCACGTCTATCTGGCGTCGTCTCGGCCGTGGCGTAGGCGCGGCACTCG
CAATCTGGGCGGCCACGCTGCTCGTCGGCCTGGCCGCGGGATCGACCGACCCGGTCAAGCCGCTGGCGGTGCTGGCAGCA
CGCACGGTTGCGTCGGGCGGCGCTGCGACGGCGGGTGCGGCCGCCGCGCAGGACGGGCCTGCATTCGCATCGGTGCGCTC
GAGTGGCGAACTCGACACGCTGCTGAAAACGTCGGGCCAGCCCGTGATGCTCGACTTCTACGCCGACTGGTGTGTGAGCT
GCAAGGAGATGGAGCATCTGACGTTTACCGACGCGCGCGTGCAGGCGCGGCTCGCGCAGCTTCACCTCGTGCGCGCGGAT
GTCACCGCGAACAACCCGGACGACCAGGCGCTGCTGAAGCGTTTCAACCTGTTCGGGCCGCCGGGCATCATCTTCTTCGA
TCGCAACGGCAACGAAATCGGGCGCGTGGTCGGCTATCAGGCCGCTGAGACGTTCCTGCGCAGCCTCGACCGGGCTGCGG
TCCCGACGGTATGA

Upstream 100 bases:

>100_bases
GCGCATCATCCTTACGAGACGCCCGAAATCGTCTCGTGGCAGACGACGGCATCGGCCGCGTACGGCCAGTGGGTGACCAG
CGAAACTCAACGTCTATTTC

Downstream 100 bases:

>100_bases
CTGTAGGTATCGCGAGCGTGCTGGTGGCGAACCGGCGCGTTGGCGCGGCCTGAGCTGACGATCGACAAGGGCAGACGGTC
CCGATCGACCGCAAAAAAAC

Product: protein-disulfide reductase

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MFNGMALPVRVRALRFLAVLLSFMLVLGGLSVARAADDFLDPSVAFKFSASESPGQVDVRFKVANGYYLYRERFAFAVKS
GQATLGDPQFPAGHVKFDQTFQKNVETYRDEVVVHVPVKQASGPFELAVTSQGCADEGICYPPAEHVVKVDGAALGAASS
PSSGDAAAAGSWFDKVTSADFAQSLLEGHGFFTIVALYFVAGVVLSLLPCSYPMIPIVSAIIIGQGTRATHARGFALSLT
YVVGMALVYTVLGIAAALVGQGLGAWLQNPWVLGAFGVLLTAFAVSLISGKDIALPARWQNGAAEASGARQGGHFVAVAA
MGALSALVVGACMTAPLFAVLAFIAHTGNALLGGAALFAMGLGLGVPLLVVGVGAGTVLPRAGAWMDGVKVFFGIVLLAA
ALWIVWPVLAGGLKMVLAALWLLIAAAALGLFTPNAGATSIWRRLGRGVGAALAIWAATLLVGLAAGSTDPVKPLAVLAA
RTVASGGAATAGAAAAQDGPAFASVRSSGELDTLLKTSGQPVMLDFYADWCVSCKEMEHLTFTDARVQARLAQLHLVRAD
VTANNPDDQALLKRFNLFGPPGIIFFDRNGNEIGRVVGYQAAETFLRSLDRAAVPTV

Sequences:

>Translated_617_residues
MFNGMALPVRVRALRFLAVLLSFMLVLGGLSVARAADDFLDPSVAFKFSASESPGQVDVRFKVANGYYLYRERFAFAVKS
GQATLGDPQFPAGHVKFDQTFQKNVETYRDEVVVHVPVKQASGPFELAVTSQGCADEGICYPPAEHVVKVDGAALGAASS
PSSGDAAAAGSWFDKVTSADFAQSLLEGHGFFTIVALYFVAGVVLSLLPCSYPMIPIVSAIIIGQGTRATHARGFALSLT
YVVGMALVYTVLGIAAALVGQGLGAWLQNPWVLGAFGVLLTAFAVSLISGKDIALPARWQNGAAEASGARQGGHFVAVAA
MGALSALVVGACMTAPLFAVLAFIAHTGNALLGGAALFAMGLGLGVPLLVVGVGAGTVLPRAGAWMDGVKVFFGIVLLAA
ALWIVWPVLAGGLKMVLAALWLLIAAAALGLFTPNAGATSIWRRLGRGVGAALAIWAATLLVGLAAGSTDPVKPLAVLAA
RTVASGGAATAGAAAAQDGPAFASVRSSGELDTLLKTSGQPVMLDFYADWCVSCKEMEHLTFTDARVQARLAQLHLVRAD
VTANNPDDQALLKRFNLFGPPGIIFFDRNGNEIGRVVGYQAAETFLRSLDRAAVPTV
>Mature_617_residues
MFNGMALPVRVRALRFLAVLLSFMLVLGGLSVARAADDFLDPSVAFKFSASESPGQVDVRFKVANGYYLYRERFAFAVKS
GQATLGDPQFPAGHVKFDQTFQKNVETYRDEVVVHVPVKQASGPFELAVTSQGCADEGICYPPAEHVVKVDGAALGAASS
PSSGDAAAAGSWFDKVTSADFAQSLLEGHGFFTIVALYFVAGVVLSLLPCSYPMIPIVSAIIIGQGTRATHARGFALSLT
YVVGMALVYTVLGIAAALVGQGLGAWLQNPWVLGAFGVLLTAFAVSLISGKDIALPARWQNGAAEASGARQGGHFVAVAA
MGALSALVVGACMTAPLFAVLAFIAHTGNALLGGAALFAMGLGLGVPLLVVGVGAGTVLPRAGAWMDGVKVFFGIVLLAA
ALWIVWPVLAGGLKMVLAALWLLIAAAALGLFTPNAGATSIWRRLGRGVGAALAIWAATLLVGLAAGSTDPVKPLAVLAA
RTVASGGAATAGAAAAQDGPAFASVRSSGELDTLLKTSGQPVMLDFYADWCVSCKEMEHLTFTDARVQARLAQLHLVRAD
VTANNPDDQALLKRFNLFGPPGIIFFDRNGNEIGRVVGYQAAETFLRSLDRAAVPTV

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=594, Percent_Identity=35.1851851851852, Blast_Score=312, Evalue=3e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 63877; Mature: 63877

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNGMALPVRVRALRFLAVLLSFMLVLGGLSVARAADDFLDPSVAFKFSASESPGQVDVR
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEE
FKVANGYYLYRERFAFAVKSGQATLGDPQFPAGHVKFDQTFQKNVETYRDEVVVHVPVKQ
EEEECCEEEHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCC
ASGPFELAVTSQGCADEGICYPPAEHVVKVDGAALGAASSPSSGDAAAAGSWFDKVTSAD
CCCCEEEEEECCCCCCCCCCCCCHHHEEEECCCCCCCCCCCCCCCCHHCCHHHHHHHHHH
FAQSLLEGHGFFTIVALYFVAGVVLSLLPCSYPMIPIVSAIIIGQGTRATHARGFALSLT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHH
YVVGMALVYTVLGIAAALVGQGLGAWLQNPWVLGAFGVLLTAFAVSLISGKDIALPARWQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCC
NGAAEASGARQGGHFVAVAAMGALSALVVGACMTAPLFAVLAFIAHTGNALLGGAALFAM
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GLGLGVPLLVVGVGAGTVLPRAGAWMDGVKVFFGIVLLAAALWIVWPVLAGGLKMVLAAL
HHHCCCHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
WLLIAAAALGLFTPNAGATSIWRRLGRGVGAALAIWAATLLVGLAAGSTDPVKPLAVLAA
HHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
RTVASGGAATAGAAAAQDGPAFASVRSSGELDTLLKTSGQPVMLDFYADWCVSCKEMEHL
HHHCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCEEEEEHHHHHHHHHHHCCC
TFTDARVQARLAQLHLVRADVTANNPDDQALLKRFNLFGPPGIIFFDRNGNEIGRVVGYQ
EEHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
AAETFLRSLDRAAVPTV
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFNGMALPVRVRALRFLAVLLSFMLVLGGLSVARAADDFLDPSVAFKFSASESPGQVDVR
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEE
FKVANGYYLYRERFAFAVKSGQATLGDPQFPAGHVKFDQTFQKNVETYRDEVVVHVPVKQ
EEEECCEEEHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCC
ASGPFELAVTSQGCADEGICYPPAEHVVKVDGAALGAASSPSSGDAAAAGSWFDKVTSAD
CCCCEEEEEECCCCCCCCCCCCCHHHEEEECCCCCCCCCCCCCCCCHHCCHHHHHHHHHH
FAQSLLEGHGFFTIVALYFVAGVVLSLLPCSYPMIPIVSAIIIGQGTRATHARGFALSLT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHH
YVVGMALVYTVLGIAAALVGQGLGAWLQNPWVLGAFGVLLTAFAVSLISGKDIALPARWQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCC
NGAAEASGARQGGHFVAVAAMGALSALVVGACMTAPLFAVLAFIAHTGNALLGGAALFAM
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GLGLGVPLLVVGVGAGTVLPRAGAWMDGVKVFFGIVLLAAALWIVWPVLAGGLKMVLAAL
HHHCCCHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
WLLIAAAALGLFTPNAGATSIWRRLGRGVGAALAIWAATLLVGLAAGSTDPVKPLAVLAA
HHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
RTVASGGAATAGAAAAQDGPAFASVRSSGELDTLLKTSGQPVMLDFYADWCVSCKEMEHL
HHHCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCEEEEEHHHHHHHHHHHCCC
TFTDARVQARLAQLHLVRADVTANNPDDQALLKRFNLFGPPGIIFFDRNGNEIGRVVGYQ
EEHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
AAETFLRSLDRAAVPTV
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]