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The map label for this gene is vllY [H]

Identifier: 78064897

GI number: 78064897

Start: 283139

End: 284236

Strand: Reverse

Name: vllY [H]

Synonym: Bcep18194_A3420

Alternate gene names: 78064897

Gene position: 284236-283139 (Counterclockwise)

Preceding gene: 78064899

Following gene: 78064895

Centisome position: 7.69

GC content: 62.66

Gene sequence:

>1098_bases
ATGCAGATCCCGAACTGGGACAACCCCGTCGGCACCGACGGCTTCGAATTCATCGAATACACGGCACCGGACCCGAAAGC
GCTCGGACAACTGTTCGAACGGATGGGTTTCACCGCGATCGCGCGCCACCGCCACAAGGACGTGACGGTGTACCGCCAGG
GCGACATCAACTTCATCATCAACGCCGAACCCGATTCATTCGCACAACGCTTCGCGCGCCTGCACGGCCCGTCGATCTGC
GCGATCGCGTTCCGCGTGCAGGATGCCGCGAAGGCGTACCAGCACGCGCTCGACCTCGGCGCCTGGGGCTTCGACAACAA
GACCGGCCCGATGGAGCTGAACATCCCGGCGATCAAGGGCATTGGCGACTCGCTGATCTACTTCGTCGACCGCTGGCGCG
GCAAGAACGGCGCGCAACCGGGCGCCATCGGCAACATCAGCATCTATGACGTCGATTTCGAGCCGATCGCCGGCGCGAAC
CCGAACCCGGTCGGCCACGGCCTCACCTATATCGACCACCTGACGCACAACGTGCATCGCGGCCGCATGCAGGAATGGGC
CGAGTTCTACGAGCGCCTGTTCAACTTCCGCGAAGTGCGCTACTTCGACATCGAAGGCAAGGTGACGGGCGTGAAGTCGA
AGGCGATGACGTCGCCGTGCGGCAAGATCCGCATCCCGATCAACGAGGAAGGCTCGGATACGGCCGGCCAGATCCAGGAA
TACCTCGACGCGTACCACGGCGAAGGCATCCAGCACATCGCGCTCGGCGCCACCGACATCTACCAGGCGGTCGATGGCCT
GCGCAGCAAGGAAGTGAAGCTGCTCGACACGATCGACACGTATTACGAACTGGTCGACCGTCGCGTGCCGAACCACGGCG
AATCGCTGGACGAACTGAAGAAGCGCAAGATCCTGATCGACGGCGCGCGCGACGACCTGCTGCTGCAGATATTCACCGAG
AACCAGATCGGGCCGATCTTCTTCGAGATCATCCAGCGCAAGGGCAACCAGGGCTTCGGCGAAGGCAACTTCAAGGCGCT
GTTCGAATCGATCGAACTCGACCAGATCCGCCGCGGCGTCGTGCAGGACAAGGCCTGA

Upstream 100 bases:

>100_bases
CGATTCGTCGCACACGCCGCCGCGTGGGCCACGTTCGACATCGAACCAGGCCGGGCATGCGCACGTCGCCCCGGTCGATC
GCCCCCACAGGAGACACGCC

Downstream 100 bases:

>100_bases
CGCCTCCGGCGGGCGGCTGCCCGGGGCAACCCGGCAGCCCGCACGATCCGGCGGCACAAAGAAAAAGGGCGGGAATCCGA
GGATTCCCGCCCTTTTTGCA

Product: 4-hydroxyphenylpyruvate dioxygenase

Products: homogentisate; CO2

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MQIPNWDNPVGTDGFEFIEYTAPDPKALGQLFERMGFTAIARHRHKDVTVYRQGDINFIINAEPDSFAQRFARLHGPSIC
AIAFRVQDAAKAYQHALDLGAWGFDNKTGPMELNIPAIKGIGDSLIYFVDRWRGKNGAQPGAIGNISIYDVDFEPIAGAN
PNPVGHGLTYIDHLTHNVHRGRMQEWAEFYERLFNFREVRYFDIEGKVTGVKSKAMTSPCGKIRIPINEEGSDTAGQIQE
YLDAYHGEGIQHIALGATDIYQAVDGLRSKEVKLLDTIDTYYELVDRRVPNHGESLDELKKRKILIDGARDDLLLQIFTE
NQIGPIFFEIIQRKGNQGFGEGNFKALFESIELDQIRRGVVQDKA

Sequences:

>Translated_365_residues
MQIPNWDNPVGTDGFEFIEYTAPDPKALGQLFERMGFTAIARHRHKDVTVYRQGDINFIINAEPDSFAQRFARLHGPSIC
AIAFRVQDAAKAYQHALDLGAWGFDNKTGPMELNIPAIKGIGDSLIYFVDRWRGKNGAQPGAIGNISIYDVDFEPIAGAN
PNPVGHGLTYIDHLTHNVHRGRMQEWAEFYERLFNFREVRYFDIEGKVTGVKSKAMTSPCGKIRIPINEEGSDTAGQIQE
YLDAYHGEGIQHIALGATDIYQAVDGLRSKEVKLLDTIDTYYELVDRRVPNHGESLDELKKRKILIDGARDDLLLQIFTE
NQIGPIFFEIIQRKGNQGFGEGNFKALFESIELDQIRRGVVQDKA
>Mature_365_residues
MQIPNWDNPVGTDGFEFIEYTAPDPKALGQLFERMGFTAIARHRHKDVTVYRQGDINFIINAEPDSFAQRFARLHGPSIC
AIAFRVQDAAKAYQHALDLGAWGFDNKTGPMELNIPAIKGIGDSLIYFVDRWRGKNGAQPGAIGNISIYDVDFEPIAGAN
PNPVGHGLTYIDHLTHNVHRGRMQEWAEFYERLFNFREVRYFDIEGKVTGVKSKAMTSPCGKIRIPINEEGSDTAGQIQE
YLDAYHGEGIQHIALGATDIYQAVDGLRSKEVKLLDTIDTYYELVDRRVPNHGESLDELKKRKILIDGARDDLLLQIFTE
NQIGPIFFEIIQRKGNQGFGEGNFKALFESIELDQIRRGVVQDKA

Specific function: Unknown

COG id: COG3185

COG function: function code ER; 4-hydroxyphenylpyruvate dioxygenase and related hemolysins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 4HPPD family [H]

Homologues:

Organism=Homo sapiens, GI4504477, Length=353, Percent_Identity=29.1784702549575, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI285002264, Length=350, Percent_Identity=28.8571428571429, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI14249394, Length=379, Percent_Identity=23.4828496042216, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17555220, Length=226, Percent_Identity=37.1681415929204, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17550752, Length=204, Percent_Identity=32.3529411764706, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21356105, Length=307, Percent_Identity=33.5504885993485, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24667510, Length=307, Percent_Identity=33.5504885993485, Blast_Score=138, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005956
- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 1.13.11.27

Molecular weight: Translated: 41130; Mature: 41130

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIPNWDNPVGTDGFEFIEYTAPDPKALGQLFERMGFTAIARHRHKDVTVYRQGDINFII
CCCCCCCCCCCCCCHHEEEECCCCHHHHHHHHHHHCHHHHHHHCCCCEEEEEECCEEEEE
NAEPDSFAQRFARLHGPSICAIAFRVQDAAKAYQHALDLGAWGFDNKTGPMELNIPAIKG
ECCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHC
IGDSLIYFVDRWRGKNGAQPGAIGNISIYDVDFEPIAGANPNPVGHGLTYIDHLTHNVHR
CCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GRMQEWAEFYERLFNFREVRYFDIEGKVTGVKSKAMTSPCGKIRIPINEEGSDTAGQIQE
HHHHHHHHHHHHHHCHHHEEEEEECCEEECCCHHHHCCCCCEEEEECCCCCCCHHHHHHH
YLDAYHGEGIQHIALGATDIYQAVDGLRSKEVKLLDTIDTYYELVDRRVPNHGESLDELK
HHHHHCCCCCEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
KRKILIDGARDDLLLQIFTENQIGPIFFEIIQRKGNQGFGEGNFKALFESIELDQIRRGV
HCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHH
VQDKA
HCCCC
>Mature Secondary Structure
MQIPNWDNPVGTDGFEFIEYTAPDPKALGQLFERMGFTAIARHRHKDVTVYRQGDINFII
CCCCCCCCCCCCCCHHEEEECCCCHHHHHHHHHHHCHHHHHHHCCCCEEEEEECCEEEEE
NAEPDSFAQRFARLHGPSICAIAFRVQDAAKAYQHALDLGAWGFDNKTGPMELNIPAIKG
ECCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHC
IGDSLIYFVDRWRGKNGAQPGAIGNISIYDVDFEPIAGANPNPVGHGLTYIDHLTHNVHR
CCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GRMQEWAEFYERLFNFREVRYFDIEGKVTGVKSKAMTSPCGKIRIPINEEGSDTAGQIQE
HHHHHHHHHHHHHHCHHHEEEEEECCEEECCCHHHHCCCCCEEEEECCCCCCCHHHHHHH
YLDAYHGEGIQHIALGATDIYQAVDGLRSKEVKLLDTIDTYYELVDRRVPNHGESLDELK
HHHHHCCCCCEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
KRKILIDGARDDLLLQIFTENQIGPIFFEIIQRKGNQGFGEGNFKALFESIELDQIRRGV
HCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHH
VQDKA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-hydroxyphenylpyruvate; O2

Specific reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA