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The map label for this gene is motA [H]

Identifier: 78064832

GI number: 78064832

Start: 211874

End: 212734

Strand: Direct

Name: motA [H]

Synonym: Bcep18194_A3355

Alternate gene names: 78064832

Gene position: 211874-212734 (Clockwise)

Preceding gene: 78064831

Following gene: 78064833

Centisome position: 5.74

GC content: 63.88

Gene sequence:

>861_bases
GTGCTGATTATCGTGGGAACACTCGTGACGCTGTTGTCCGTCTTCGGCGGTTATGCGCTGGCAGGCGGGCATCTGGGCGC
CTTGATCCAGCCGGTCGAGATCCTGATGATCGTGGGTGCCGGTGTCGGCGCGTTCATCCTCGGCAATGGCGGCAAGACCA
TCAAGGCCACGCTGCGCGTGCTGCCGACGCTCTTCAAGGGCTCGAAATACACGAAGGATGTCTACATGGAGCTGATGGCG
CTTCTTTACGTGCTGCTCGCGAAGGCACGCAAGGAAGGCACGCTCACGCTCGAGGCCGACATCGACGATCCCGAAAAGAG
CCCGATCTTCACGCAATACCCGAAAATCCTCGCCGATCATCACATCGTCGAATTCCTGACCGACTACCTGCGCCTGATGG
TGGGCGGCAACATGAACGCGTTCGAGATCGAAAGCCTGATGGACGAGGAGATCGAGACGCACCACGCGGAAGGCGAAGGC
CCCGCGCACGCACTGATGCGCGTCGGCGACGCGATGCCGGCGTTCGGTATCGTCGCGGCCGTGATGGGCGTCGTGCACAC
GATGGCGTCCGCCGACAAGCCGCCCGCGGTGCTCGGCGCGATGATCGCGCAGGCGCTGGTCGGCACGTTCCTCGGGATCC
TGCTGTCGTACGGGCTGATCGGGCCGCTCGCGAGCCTCGCGGAGCAGCGCGTCGCCGAGTCGACCAAGATGTTCCAGTGC
ATCAAGGTGACGATCCTCGCGACGCTGAACGGCTATGCGCCGGCGATCGCGGTCGAGTTCGGCCGCAAGGTGCTGTTCTC
GACCGAGCGCCCGTCGTTCTCCGAGCTCGAAGAACATGTGCGCCGCGTGAAGGCGAAGTGA

Upstream 100 bases:

>100_bases
CGTCGGGCCGCCGCCTGGCCGCCCGCGAAAGTTTTCCTGCCGACTGCCGTAAACCTGTTTAACGGCGGTCTCCCCGCCGG
TCATTCGTGAGGGACAGGCA

Downstream 100 bases:

>100_bases
CGCGGAGCGCCCAATGAGCAAGAGCAAGGATCGCGCAATCGTCGTCAAGCGGGTGGCCCCGTCGAAGAAGGGCCACCACG
GCGGCGCATGGAAGCTCGCG

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLIIVGTLVTLLSVFGGYALAGGHLGALIQPVEILMIVGAGVGAFILGNGGKTIKATLRVLPTLFKGSKYTKDVYMELMA
LLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADHHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEG
PAHALMRVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
IKVTILATLNGYAPAIAVEFGRKVLFSTERPSFSELEEHVRRVKAK

Sequences:

>Translated_286_residues
MLIIVGTLVTLLSVFGGYALAGGHLGALIQPVEILMIVGAGVGAFILGNGGKTIKATLRVLPTLFKGSKYTKDVYMELMA
LLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADHHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEG
PAHALMRVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
IKVTILATLNGYAPAIAVEFGRKVLFSTERPSFSELEEHVRRVKAK
>Mature_286_residues
MLIIVGTLVTLLSVFGGYALAGGHLGALIQPVEILMIVGAGVGAFILGNGGKTIKATLRVLPTLFKGSKYTKDVYMELMA
LLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADHHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEG
PAHALMRVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
IKVTILATLNGYAPAIAVEFGRKVLFSTERPSFSELEEHVRRVKAK

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=284, Percent_Identity=64.0845070422535, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30654; Mature: 30654

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIVGTLVTLLSVFGGYALAGGHLGALIQPVEILMIVGAGVGAFILGNGGKTIKATLRV
CEEEHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
LPTLFKGSKYTKDVYMELMALLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
HIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEGPAHALMRVGDAMPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHH
VMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVTILATLNGYAPAIAVEFGRKVLFSTERPSFSELEEHVRRVKAK
HHHHHHHHHCCCCHHHHHHHCCHHEECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIIVGTLVTLLSVFGGYALAGGHLGALIQPVEILMIVGAGVGAFILGNGGKTIKATLRV
CEEEHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
LPTLFKGSKYTKDVYMELMALLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
HIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEGPAHALMRVGDAMPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHH
VMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVTILATLNGYAPAIAVEFGRKVLFSTERPSFSELEEHVRRVKAK
HHHHHHHHHCCCCHHHHHHHCCHHEECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]