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The map label for this gene is putA

Identifier: 78064771

GI number: 78064771

Start: 130999

End: 134931

Strand: Direct

Name: putA

Synonym: Bcep18194_A3294

Alternate gene names: 78064771

Gene position: 130999-134931 (Clockwise)

Preceding gene: 78064770

Following gene: 78064772

Centisome position: 3.55

GC content: 69.62

Gene sequence:

>3933_bases
ATGGCAAGCACGACTCTCGGCGTCAAAGTCGACGACCTTCTCCGCTCGCGTCTCAAGGACGCCGCCGCGCGTCTCGAGCG
CACTCCCCACTGGCTGATCAAGCAGGCGATCTTCGCGTATCTCGAGCGGATCGAGCACGGCCAGTTGCCGCCCGAGCTGT
CGGGTCACAGCGGCGTGACGGAGCTCGCCGACGGCCAGGTCGCGGACGGCGACGACGACAACTCGCCGCATCCGTTCCTC
GAGTTCGCGCAGAACGTGCAGCCGCAATCGGTGCTGCGCGCGGCGATCACGGCTGCGTATCGCCGCCCCGAGCCGGAATG
CGTGCCGTTCCTGCTCGGGCAGGCGCGCCTGCCCGCGAACCTGCAGGCGGACGTGCAGGCGCTCGCGACCAAGCTCGTCG
AGGCGCTGCGCGAGAAGAGCTCGGGCGGCGGCGTCGAAGGGCTGATCCACGAGTTCTCGCTGTCGAGCCAGGAAGGCGTC
GCGCTGATGTGCCTCGCCGAAGCGCTGCTGCGCATTCCCGATCGCGCGACGCGCGATGCGCTGATTCGCGACAAGATCAG
CAAGGGCGACTGGCGCTCGCACGTCGGCCACGCGCCGTCGCTGTTCGTGAACGCGGCCACGTGGGGGCTGATGATCACCG
GCAAGCTGGTGACGACCAACAGCGAAGCCGGGCTGTCGTCGGCGCTGACGCGCCTGATCGGCCGCGGCGGCGAGCCGCTG
ATCCGCAAGGGCGTCGACATGGCGATGCGCCTGATGGGCGAGCAGTTCGTCACCGGCGAGACGATTTCCGAAGCGCTCGC
GAACAGCCGCAAGTACGAAGCGCGCGGCTTCCGCTACTCGTACGACATGCTCGGCGAAGCGGCGACCACCGAAGAGGATG
CGCAGCGCTACTACGCGTCGTACGAACAGGCGATCCACGCGATCGGCAAGGCAGCCGGCGGCCGCGGCATCTACGAAGGC
CCGGGCATCTCGATCAAGCTGTCGGCGCTGCACGCGCGCTACTCGCGCTCGCAGCAGGACCGCACGATGAGCGAGCTGCT
GCCGCGCGTGCGCGCGCTCGCGCTGCTCGCGCGCCGCTACGACATCGGCCTGAACATCGATGCTGAAGAAGCCGACCGCC
TCGAACTGTCGCTCGACCTGCTCGAGGCGCTGTGCTTCGATCCGGATCTCGCGGGCTGGAACGGCATCGGCTTTGTGGTG
CAGGGCTACCAGAAGCGCTGCCCGTTCGTGATCGACTACCTGATCGATCTCGCGCGCCGCAGCCGTCACCGCCTGATGAT
CCGCCTCGTGAAGGGCGCGTACTGGGATACCGAGATCAAGCGTGCGCAGGTCGACGGCCTCGAAGGCTATCCGGTCTATA
CGCGCAAGATCTACACCGACGTGTCGTACCTCGCGTGCGCGAAGAAGCTGCTCGCGGCGCCGGACGCCGTGTACCCGCAG
TTCGCGACGCACAACGCGCACACGCTGGCCGCGATCTACCAGCTCGCGGGCCAGAACTACTACCCGGGCCAGTACGAATT
CCAGTGCCTGCACGGGATGGGCGAGCCGCTGTACGAGGAAGTCACGGGCCGCGACAAGCTCAACCGTCCGTGCCGCGTGT
ACGCGCCGGTCGGCACGCACGAGACGCTGCTCGCGTACCTGGTGCGCCGCCTGCTCGAGAACGGCGCGAACACGTCGTTC
GTGAACCGCATCGCGGATAAAACCGTGGCGGTGAAGGAGCTGGTTGCCGATCCGGTCGACGAAGCGTCGAAGGTCGTGCC
GCTCGGCGCACCGCACGCGAAGATCCCGCTGCCGCGCAACCTGTACGGCGACGAGCGTCCCAACTCGATGGGTCTCGACC
TGTCGAACGAACACCGCCTCGCGTCGCTGTCGTCCGCGCTGCTCGCGAGCGCGCATTTCCCGTGGCGCGCGGCGCCGATG
CTCGCCGACGACGCGCTCGCCGACGCACCGGCCCGCGACGTGCGCAACCCGGCCGACCAGCGCGACCTGGTCGGCACGGT
CAGCGAAGCGACGGCCGAACACGTGAGCGCGGCACTCGCGCACGCGGTGGCCGCCGCGCCGATCTGGCAGGCGACGCCGG
TCGATGCACGCGCCGATTGCCTGGTGCGCGCGGCCGACCTGCTCGAAGCGCAGATGCACACGCTGATGGGCCTGATCGTG
CGCGAAGCCGGCAAATCGCTGCCTAACGCGATCGCCGAGATCCGCGAAGCGGTCGACTTCCTGCGCTACTACGCCGCACA
GATCCGCGACGAATTCTCGAACGACACGCACCGCCCGCTGGGCCCCGTGGTCTGTATCAGCCCGTGGAACTTCCCGCTCG
CGATCTTCATGGGCCAGGTCGCCGCGGCACTCGCCGCCGGCAACACGGTGCTCGCGAAGCCGGCCGAACAGACGCCGCTG
ATCGCCGCGCAGGCCGTGCGCCTGCTGCGCGAGGCCGGCGTGCCGGCCGGCGCGGTGCAACTGCTGCCGGGCACCGGCGA
GACCGTCGGCGCGGCGCTGGTGGCCGACGCGCGTACGCGTGCGGTGATGTTCACCGGCTCGACCGAAGTCGCGCGCCTGA
TCAACAAGACGCTGTCCGCGCGCCTCGACCCGGACGGCAAGCCGATCCCGCTGATCGCCGAAACGGGCGGCCAGAACGCG
ATGATCGTCGACTCGTCGGCGCTCGCGGAGCAGGTCGTCGCGGACGTGATGCAGTCGTCTTTCGACTCGGCCGGTCAACG
GTGTTCGGCGCTGCGCGTTCTGTGTCTGCAGGACGATGTTGCGGACCGCACGCTGACGATGCTGAAGGGCGCGATGCACG
AGCTGGCGCTCGGCAACCCCGACCGCCTGTCGACGGACGTCGGCCCGGTGATCGACGGTGAAGCGAAGCAGACGATCGAC
ACGCACGTCGCGGCGATGAAGGACAAGGGGCACGGCGTCACGCAGCTGCCGGCCCCCGAGGCCTGCGCGCACGGCACCTT
CGTGCCGCCGACGCTGATCGAGATCGGCAGCATCGACGAGCTGAAGCGCGAAGTGTTCGGCCCCGTGCTGCACGTGGTGC
GTTACCGCCGCAGCCAGCTCGACAAGCTGCTGGAGCAGATCCGCGCGACCGGCTACGGCCTGACGCTCGGCATCCACACG
CGGATCGACGAGACGATCGCGCACGTGATCTCGAATGCGCACGTCGGTAACATCTACGTGAACCGCAACGTGATCGGCGC
GGTGGTCGGCGTGCAGCCGTTCGGCGGCGAAGGGCTGTCGGGCACGGGCCCGAAGGCCGGCGGCGCGCTGTACCTGCAGC
GCCTGCTCGCGACGCGTCCGTCGGGCCTGCCGCGTTCGCTCGCGCAGACGCTGATCGCGGACGGCGCGGTGGAAGGCGAC
GCGCGCGGCAACCCGGCGGCGGCGCTCACGACGCTGCGTGACTGGCTGATCGAGCAGCGCGAGCCGGTGCTGGCGGCACG
TTGCGACGGCTATCTGGCCCAGGTGCCGGCCGGTGCGACCGCAGTGTTGAGCGGTCCGACGGGCGAGCGAAACACGTATA
CACTCGGCCCGCGCGGCACGGTGTTGTGTGTCGCGGCGACGCCGGGCGGGGCGCGCGCGCAGTTCGCGGCGGTGCTGGCG
ACCGGCAACCGTGCGCTGTTCGCGGGCGCGGCCGGCGAGGCGCTGGTCGCCGCGCTGCCGGCATCGTTGAAGGCACACGC
GGTCGTGCGCAAGCAGGCCGACGCGCCGTTCGACGCGGTGCTGTTCGAAGGCGACAGCGACGAACTGCAGACGCTCGTGA
AGGACGTCGCGCAGCGGCCGGGCCCGATCGTGTCGGTGCAGGGCGTGTCGGTGGGCGCGTTCGAGAACGGCGATGCGGAA
GATTACGCGCTGGAACGGCTGTTGACGGAGCGCTCGGTGAGCGTGAACACGGCCGCGGCGGGTGGCAATGCGAATTTGAT
GACGATCGGCTGA

Upstream 100 bases:

>100_bases
CTATCTCGTAATTTGGTTGCACCTTTTTATTGCGTGCCGTAGGATTTCGCGCATCCTCTCACACCATATTGCCGGGCTCG
CACCGGCGCACGAACCCACC

Downstream 100 bases:

>100_bases
TCATCCTTGCCGTTCGGATCAAACAAAGGAAGCGGCAAGGCGATCCCGAAGCCGCTCCATTTACCCTGGTACCAAGGAGA
TGCTATGCAACACACGATGA

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1310; Mature: 1309

Protein sequence:

>1310_residues
MASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVTELADGQVADGDDDNSPHPFL
EFAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPANLQADVQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGV
ALMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYASYEQAIHAIGKAAGGRGIYEG
PGISIKLSALHARYSRSQQDRTMSELLPRVRALALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPDLAGWNGIGFVV
QGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQ
FATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSF
VNRIADKTVAVKELVADPVDEASKVVPLGAPHAKIPLPRNLYGDERPNSMGLDLSNEHRLASLSSALLASAHFPWRAAPM
LADDALADAPARDVRNPADQRDLVGTVSEATAEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
REAGKSLPNAIAEIREAVDFLRYYAAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPL
IAAQAVRLLREAGVPAGAVQLLPGTGETVGAALVADARTRAVMFTGSTEVARLINKTLSARLDPDGKPIPLIAETGGQNA
MIVDSSALAEQVVADVMQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDGEAKQTID
THVAAMKDKGHGVTQLPAPEACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHT
RIDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPSGLPRSLAQTLIADGAVEGD
ARGNPAAALTTLRDWLIEQREPVLAARCDGYLAQVPAGATAVLSGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLA
TGNRALFAGAAGEALVAALPASLKAHAVVRKQADAPFDAVLFEGDSDELQTLVKDVAQRPGPIVSVQGVSVGAFENGDAE
DYALERLLTERSVSVNTAAAGGNANLMTIG

Sequences:

>Translated_1310_residues
MASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVTELADGQVADGDDDNSPHPFL
EFAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPANLQADVQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGV
ALMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYASYEQAIHAIGKAAGGRGIYEG
PGISIKLSALHARYSRSQQDRTMSELLPRVRALALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPDLAGWNGIGFVV
QGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQ
FATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSF
VNRIADKTVAVKELVADPVDEASKVVPLGAPHAKIPLPRNLYGDERPNSMGLDLSNEHRLASLSSALLASAHFPWRAAPM
LADDALADAPARDVRNPADQRDLVGTVSEATAEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
REAGKSLPNAIAEIREAVDFLRYYAAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPL
IAAQAVRLLREAGVPAGAVQLLPGTGETVGAALVADARTRAVMFTGSTEVARLINKTLSARLDPDGKPIPLIAETGGQNA
MIVDSSALAEQVVADVMQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDGEAKQTID
THVAAMKDKGHGVTQLPAPEACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHT
RIDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPSGLPRSLAQTLIADGAVEGD
ARGNPAAALTTLRDWLIEQREPVLAARCDGYLAQVPAGATAVLSGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLA
TGNRALFAGAAGEALVAALPASLKAHAVVRKQADAPFDAVLFEGDSDELQTLVKDVAQRPGPIVSVQGVSVGAFENGDAE
DYALERLLTERSVSVNTAAAGGNANLMTIG
>Mature_1309_residues
ASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVTELADGQVADGDDDNSPHPFLE
FAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPANLQADVQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGVA
LMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPLI
RKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYASYEQAIHAIGKAAGGRGIYEGP
GISIKLSALHARYSRSQQDRTMSELLPRVRALALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPDLAGWNGIGFVVQ
GYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQF
ATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFV
NRIADKTVAVKELVADPVDEASKVVPLGAPHAKIPLPRNLYGDERPNSMGLDLSNEHRLASLSSALLASAHFPWRAAPML
ADDALADAPARDVRNPADQRDLVGTVSEATAEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIVR
EAGKSLPNAIAEIREAVDFLRYYAAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLI
AAQAVRLLREAGVPAGAVQLLPGTGETVGAALVADARTRAVMFTGSTEVARLINKTLSARLDPDGKPIPLIAETGGQNAM
IVDSSALAEQVVADVMQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDGEAKQTIDT
HVAAMKDKGHGVTQLPAPEACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHTR
IDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPSGLPRSLAQTLIADGAVEGDA
RGNPAAALTTLRDWLIEQREPVLAARCDGYLAQVPAGATAVLSGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLAT
GNRALFAGAAGEALVAALPASLKAHAVVRKQADAPFDAVLFEGDSDELQTLVKDVAQRPGPIVSVQGVSVGAFENGDAED
YALERLLTERSVSVNTAAAGGNANLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=453, Percent_Identity=32.4503311258278, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI153266822, Length=450, Percent_Identity=29.3333333333333, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI25777730, Length=444, Percent_Identity=30.4054054054054, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI25777732, Length=447, Percent_Identity=30.4250559284116, Blast_Score=167, Evalue=5e-41,
Organism=Homo sapiens, GI25777724, Length=459, Percent_Identity=28.9760348583878, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI25777736, Length=467, Percent_Identity=30.406852248394, Blast_Score=163, Evalue=9e-40,
Organism=Homo sapiens, GI25777734, Length=467, Percent_Identity=30.406852248394, Blast_Score=163, Evalue=9e-40,
Organism=Homo sapiens, GI238859541, Length=467, Percent_Identity=30.406852248394, Blast_Score=163, Evalue=1e-39,
Organism=Homo sapiens, GI25777728, Length=413, Percent_Identity=29.5399515738499, Blast_Score=160, Evalue=1e-38,
Organism=Homo sapiens, GI21614513, Length=432, Percent_Identity=30.5555555555556, Blast_Score=160, Evalue=1e-38,
Organism=Homo sapiens, GI12007648, Length=439, Percent_Identity=29.3849658314351, Blast_Score=151, Evalue=5e-36,
Organism=Homo sapiens, GI238814322, Length=423, Percent_Identity=27.6595744680851, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI4507229, Length=497, Percent_Identity=28.9738430583501, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI25777721, Length=510, Percent_Identity=28.0392156862745, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI310128103, Length=461, Percent_Identity=26.2472885032538, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI188035924, Length=461, Percent_Identity=26.2472885032538, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI310128093, Length=459, Percent_Identity=26.797385620915, Blast_Score=132, Evalue=3e-30,
Organism=Homo sapiens, GI115387104, Length=449, Percent_Identity=26.7260579064588, Blast_Score=131, Evalue=4e-30,
Organism=Homo sapiens, GI11095441, Length=425, Percent_Identity=27.2941176470588, Blast_Score=131, Evalue=5e-30,
Organism=Homo sapiens, GI25952152, Length=433, Percent_Identity=28.4064665127021, Blast_Score=126, Evalue=2e-28,
Organism=Homo sapiens, GI25777726, Length=459, Percent_Identity=25.2723311546841, Blast_Score=117, Evalue=7e-26,
Organism=Homo sapiens, GI310128091, Length=394, Percent_Identity=27.1573604060914, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI71773324, Length=385, Percent_Identity=25.1948051948052, Blast_Score=99, Evalue=4e-20,
Organism=Homo sapiens, GI310128087, Length=304, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=9e-20,
Organism=Homo sapiens, GI4502043, Length=329, Percent_Identity=24.9240121580547, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI238814371, Length=329, Percent_Identity=24.9240121580547, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI206597441, Length=459, Percent_Identity=25.0544662309368, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI206597439, Length=459, Percent_Identity=25.0544662309368, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI22907049, Length=459, Percent_Identity=25.0544662309368, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI310128089, Length=334, Percent_Identity=25.748502994012, Blast_Score=88, Evalue=6e-17,
Organism=Homo sapiens, GI310128095, Length=320, Percent_Identity=25.9375, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI73695881, Length=353, Percent_Identity=22.9461756373938, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI73695879, Length=353, Percent_Identity=22.9461756373938, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI4557303, Length=331, Percent_Identity=22.9607250755287, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI73466520, Length=331, Percent_Identity=22.9607250755287, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI310128101, Length=223, Percent_Identity=27.3542600896861, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI310128099, Length=222, Percent_Identity=27.4774774774775, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI301500698, Length=427, Percent_Identity=24.824355971897, Blast_Score=77, Evalue=8e-14,
Organism=Homo sapiens, GI310128097, Length=267, Percent_Identity=25.8426966292135, Blast_Score=75, Evalue=3e-13,
Organism=Escherichia coli, GI1787250, Length=1338, Percent_Identity=65.9940209267564, Blast_Score=1714, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=462, Percent_Identity=30.5194805194805, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI1788042, Length=448, Percent_Identity=31.4732142857143, Blast_Score=162, Evalue=1e-40,
Organism=Escherichia coli, GI1787715, Length=447, Percent_Identity=32.2147651006711, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI1787684, Length=460, Percent_Identity=29.1304347826087, Blast_Score=158, Evalue=2e-39,
Organism=Escherichia coli, GI1787558, Length=411, Percent_Identity=30.4136253041363, Blast_Score=144, Evalue=4e-35,
Organism=Escherichia coli, GI87081896, Length=418, Percent_Identity=28.9473684210526, Blast_Score=139, Evalue=1e-33,
Organism=Escherichia coli, GI1786504, Length=465, Percent_Identity=28.3870967741935, Blast_Score=137, Evalue=4e-33,
Organism=Escherichia coli, GI87082295, Length=453, Percent_Identity=28.2560706401766, Blast_Score=130, Evalue=5e-31,
Organism=Escherichia coli, GI87081926, Length=443, Percent_Identity=26.1851015801354, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1787653, Length=261, Percent_Identity=24.1379310344828, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17534447, Length=461, Percent_Identity=31.236442516269, Blast_Score=180, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI25144435, Length=453, Percent_Identity=32.0088300220751, Blast_Score=179, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI32564736, Length=409, Percent_Identity=33.0073349633252, Blast_Score=173, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17562198, Length=493, Percent_Identity=29.6146044624746, Blast_Score=167, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI115534176, Length=454, Percent_Identity=29.5154185022026, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI115532534, Length=375, Percent_Identity=31.7333333333333, Blast_Score=152, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25143874, Length=504, Percent_Identity=25.9920634920635, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=505, Percent_Identity=26.1386138613861, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32564151, Length=412, Percent_Identity=29.3689320388349, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI133930964, Length=441, Percent_Identity=27.2108843537415, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17551164, Length=455, Percent_Identity=26.8131868131868, Blast_Score=132, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI71986308, Length=427, Percent_Identity=27.8688524590164, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17534119, Length=456, Percent_Identity=28.0701754385965, Blast_Score=129, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71995606, Length=443, Percent_Identity=26.6365688487585, Blast_Score=117, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71995613, Length=400, Percent_Identity=26.5, Blast_Score=114, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=29.4701986754967, Blast_Score=110, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25146391, Length=412, Percent_Identity=23.5436893203883, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25146394, Length=412, Percent_Identity=23.5436893203883, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32566756, Length=412, Percent_Identity=23.5436893203883, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17564084, Length=330, Percent_Identity=25.4545454545455, Blast_Score=94, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6320917, Length=457, Percent_Identity=32.1663019693654, Blast_Score=187, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6321826, Length=485, Percent_Identity=30.1030927835052, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6325196, Length=462, Percent_Identity=31.1688311688312, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=451, Percent_Identity=28.3813747228381, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6323821, Length=466, Percent_Identity=30.2575107296137, Blast_Score=161, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6323822, Length=474, Percent_Identity=29.1139240506329, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319478, Length=465, Percent_Identity=27.5268817204301, Blast_Score=133, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=374, Percent_Identity=25.4010695187166, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323757, Length=336, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129399, Length=444, Percent_Identity=29.5045045045045, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281362580, Length=471, Percent_Identity=27.8131634819533, Blast_Score=160, Evalue=8e-39,
Organism=Drosophila melanogaster, GI62472918, Length=471, Percent_Identity=27.8131634819533, Blast_Score=160, Evalue=8e-39,
Organism=Drosophila melanogaster, GI62472926, Length=471, Percent_Identity=27.8131634819533, Blast_Score=160, Evalue=8e-39,
Organism=Drosophila melanogaster, GI62472936, Length=471, Percent_Identity=27.8131634819533, Blast_Score=160, Evalue=8e-39,
Organism=Drosophila melanogaster, GI21356737, Length=471, Percent_Identity=27.8131634819533, Blast_Score=160, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24650465, Length=449, Percent_Identity=28.0623608017817, Blast_Score=157, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24668425, Length=481, Percent_Identity=25.987525987526, Blast_Score=156, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24668417, Length=481, Percent_Identity=25.987525987526, Blast_Score=156, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24668413, Length=481, Percent_Identity=25.987525987526, Blast_Score=156, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24585660, Length=479, Percent_Identity=26.7223382045929, Blast_Score=147, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24666674, Length=457, Percent_Identity=28.0087527352298, Blast_Score=144, Evalue=4e-34,
Organism=Drosophila melanogaster, GI28574525, Length=492, Percent_Identity=27.0325203252033, Blast_Score=143, Evalue=8e-34,
Organism=Drosophila melanogaster, GI28571806, Length=459, Percent_Identity=25.0544662309368, Blast_Score=132, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28571802, Length=459, Percent_Identity=25.0544662309368, Blast_Score=132, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28571800, Length=459, Percent_Identity=25.0544662309368, Blast_Score=132, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28571798, Length=459, Percent_Identity=25.0544662309368, Blast_Score=132, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28571796, Length=459, Percent_Identity=25.0544662309368, Blast_Score=132, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28571794, Length=459, Percent_Identity=25.0544662309368, Blast_Score=132, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24638878, Length=428, Percent_Identity=26.4018691588785, Blast_Score=111, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24638876, Length=428, Percent_Identity=26.4018691588785, Blast_Score=111, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281360299, Length=335, Percent_Identity=27.7611940298507, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281360297, Length=335, Percent_Identity=27.7611940298507, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281360295, Length=335, Percent_Identity=27.7611940298507, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24586250, Length=335, Percent_Identity=27.7611940298507, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281360301, Length=331, Percent_Identity=27.190332326284, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45552499, Length=335, Percent_Identity=25.9701492537313, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360303, Length=331, Percent_Identity=25.9818731117825, Blast_Score=92, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 140181; Mature: 140050

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVT
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
ELADGQVADGDDDNSPHPFLEFAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPAN
HHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCC
LQADVQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDA
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHH
LIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
HHHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHH
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYAS
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHH
YEQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQDRTMSELLPRVRALALLARRY
HHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGLNIDAEEADRLELSLDLLEALCFDPDLAGWNGIGFVVQGYQKRCPFVIDYLIDLARR
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEECHHHCCCHHHHHHHHHHHH
SRHRLMIRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQ
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTH
HHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCH
ETLLAYLVRRLLENGANTSFVNRIADKTVAVKELVADPVDEASKVVPLGAPHAKIPLPRN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCEEECCCCCCCCCCCCC
LYGDERPNSMGLDLSNEHRLASLSSALLASAHFPWRAAPMLADDALADAPARDVRNPADQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHCCCCCH
RDLVGTVSEATAEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
REAGKSLPNAIAEIREAVDFLRYYAAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHH
AAALAAGNTVLAKPAEQTPLIAAQAVRLLREAGVPAGAVQLLPGTGETVGAALVADARTR
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCE
AVMFTGSTEVARLINKTLSARLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVMQSS
EEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
FDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDGEAKQTID
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
THVAAMKDKGHGVTQLPAPEACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQL
HHHHHHHCCCCCCCCCCCCHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DKLLEQIRATGYGLTLGIHTRIDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLS
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEECCCCCCCCCC
GTGPKAGGALYLQRLLATRPSGLPRSLAQTLIADGAVEGDARGNPAAALTTLRDWLIEQR
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
EPVLAARCDGYLAQVPAGATAVLSGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLA
CCHHHHHCCCHHEECCCCCEEEEECCCCCCCCEEECCCCEEEEEEECCCCCHHHEEEEEE
TGNRALFAGAAGEALVAALPASLKAHAVVRKQADAPFDAVLFEGDSDELQTLVKDVAQRP
ECCCEEEECCCCHHHHHHHCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCC
GPIVSVQGVSVGAFENGDAEDYALERLLTERSVSVNTAAAGGNANLMTIG
CCEEEECCEEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC
>Mature Secondary Structure 
ASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVT
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
ELADGQVADGDDDNSPHPFLEFAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPAN
HHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCC
LQADVQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDA
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHH
LIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
HHHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHH
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYAS
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHH
YEQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQDRTMSELLPRVRALALLARRY
HHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGLNIDAEEADRLELSLDLLEALCFDPDLAGWNGIGFVVQGYQKRCPFVIDYLIDLARR
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEECHHHCCCHHHHHHHHHHHH
SRHRLMIRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQ
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTH
HHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCH
ETLLAYLVRRLLENGANTSFVNRIADKTVAVKELVADPVDEASKVVPLGAPHAKIPLPRN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCEEECCCCCCCCCCCCC
LYGDERPNSMGLDLSNEHRLASLSSALLASAHFPWRAAPMLADDALADAPARDVRNPADQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHCCCCCH
RDLVGTVSEATAEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
REAGKSLPNAIAEIREAVDFLRYYAAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHH
AAALAAGNTVLAKPAEQTPLIAAQAVRLLREAGVPAGAVQLLPGTGETVGAALVADARTR
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCE
AVMFTGSTEVARLINKTLSARLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVMQSS
EEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
FDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDGEAKQTID
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
THVAAMKDKGHGVTQLPAPEACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQL
HHHHHHHCCCCCCCCCCCCHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DKLLEQIRATGYGLTLGIHTRIDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLS
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEECCCCCCCCCC
GTGPKAGGALYLQRLLATRPSGLPRSLAQTLIADGAVEGDARGNPAAALTTLRDWLIEQR
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
EPVLAARCDGYLAQVPAGATAVLSGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLA
CCHHHHHCCCHHEECCCCCEEEEECCCCCCCCEEECCCCEEEEEEECCCCCHHHEEEEEE
TGNRALFAGAAGEALVAALPASLKAHAVVRKQADAPFDAVLFEGDSDELQTLVKDVAQRP
ECCCEEEECCCCHHHHHHHCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCC
GPIVSVQGVSVGAFENGDAEDYALERLLTERSVSVNTAAAGGNANLMTIG
CCEEEECCEEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]