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The map label for this gene is pheC [H]

Identifier: 78064768

GI number: 78064768

Start: 125843

End: 126643

Strand: Reverse

Name: pheC [H]

Synonym: Bcep18194_A3291

Alternate gene names: 78064768

Gene position: 126643-125843 (Counterclockwise)

Preceding gene: 78064773

Following gene: 78064747

Centisome position: 3.43

GC content: 65.42

Gene sequence:

>801_bases
ATGAAGACACTCGCCACGCTCGCCGCCACCGCGCTGCTTTGCTGTGCCGCCGCGCACGCGCAGACCGGCGCGGGCGCCGC
TGCCGCCGCACCGGGCGCCGGCTCGCGGCTCGACGACGTGCTCGCGCGCGGCACGCTGCGCGTGTGCACGACGGGCGACT
ACAAGCCGTATTCGTACTACCGCGCGGACGGCCGCTTCGAGGGCATCGACATCGACATGGCCGAATCGCTCGCGAAATCG
CTCGGCGTGAAGACCGACTACGTGAAGACGAGCTGGCCGAACCTGACCGGCGATTTCGTCGCGAAATGCGACATCGCGGT
GGGTGGCGTGTCGACGACGCTCGAGCGCCAGAAGCGCGTGTTCTTCACGCAGCCGTACGTGGTCGACGGCAAGACGCCGA
TCGTGCGCTGCGCGGACGCCGACAAATACCAGACCGTCGCGCAGATCGACCGGCCGGAAACGCGCGTGATCGTGAACCCG
GGCGGCACCAACGAGCGTTTCGCGAAGCAGTACTTCACGCACGCGAACCTCACCGTCTATCCGGACAACGTAACGATCTT
CAAGCAGATCCTCGCCGGCAAGGCGGACGTGATGGTGACGGATGCGTCCGAGACACTGCTGCAGCAAAAGCTGAATCCGG
GCCTGTGCTCGGTGCATCCGGACAAGCCGTTCCAGTTCGGCGAGAAGGCGTACATGGTGCCGCGCGGCGATGTCGCGTTC
CAGCAGTACGTCGATCAGTGGCTGCATCTCGCGCTGTCGACCGGCGAATACCAGGCGATTTCGGACAAATGGCTGAAGTA
A

Upstream 100 bases:

>100_bases
CGTCGGGCTGCGCTTGCCGACGCGATGGCGGCCATATGACGCGCGCGATGGCTCCGTTATGATCGGACGCTCATATCGAA
CGAAACGAAGGAGGAGACCG

Downstream 100 bases:

>100_bases
TCAGGCCCGCGCACGGCGGCCGATAGCGGGCACCGACCCCGCGGCCACCGCCGCAAAAGTCGCTGCGCGGCGGCGGCCGA
AGTGCCGCCGTTACACTTCG

Product: cyclohexadienyl dehydratase

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MKTLATLAATALLCCAAAHAQTGAGAAAAAPGAGSRLDDVLARGTLRVCTTGDYKPYSYYRADGRFEGIDIDMAESLAKS
LGVKTDYVKTSWPNLTGDFVAKCDIAVGGVSTTLERQKRVFFTQPYVVDGKTPIVRCADADKYQTVAQIDRPETRVIVNP
GGTNERFAKQYFTHANLTVYPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRGDVAF
QQYVDQWLHLALSTGEYQAISDKWLK

Sequences:

>Translated_266_residues
MKTLATLAATALLCCAAAHAQTGAGAAAAAPGAGSRLDDVLARGTLRVCTTGDYKPYSYYRADGRFEGIDIDMAESLAKS
LGVKTDYVKTSWPNLTGDFVAKCDIAVGGVSTTLERQKRVFFTQPYVVDGKTPIVRCADADKYQTVAQIDRPETRVIVNP
GGTNERFAKQYFTHANLTVYPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRGDVAF
QQYVDQWLHLALSTGEYQAISDKWLK
>Mature_266_residues
MKTLATLAATALLCCAAAHAQTGAGAAAAAPGAGSRLDDVLARGTLRVCTTGDYKPYSYYRADGRFEGIDIDMAESLAKS
LGVKTDYVKTSWPNLTGDFVAKCDIAVGGVSTTLERQKRVFFTQPYVVDGKTPIVRCADADKYQTVAQIDRPETRVIVNP
GGTNERFAKQYFTHANLTVYPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRGDVAF
QQYVDQWLHLALSTGEYQAISDKWLK

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=264, Percent_Identity=26.5151515151515, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787085, Length=216, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787088, Length=231, Percent_Identity=25.1082251082251, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 28989; Mature: 28989

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLATLAATALLCCAAAHAQTGAGAAAAAPGAGSRLDDVLARGTLRVCTTGDYKPYSYY
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEECCCCCCCEEE
RADGRFEGIDIDMAESLAKSLGVKTDYVKTSWPNLTGDFVAKCDIAVGGVSTTLERQKRV
ECCCEEECCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHCE
FFTQPYVVDGKTPIVRCADADKYQTVAQIDRPETRVIVNPGGTNERFAKQYFTHANLTVY
EEECCEEECCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEE
PDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRGDVAF
CCCHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCCEECCCCCCCCCCCEEEECCCCCHHH
QQYVDQWLHLALSTGEYQAISDKWLK
HHHHHHHHHHHHCCCCCCCHHHHCCC
>Mature Secondary Structure
MKTLATLAATALLCCAAAHAQTGAGAAAAAPGAGSRLDDVLARGTLRVCTTGDYKPYSYY
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEECCCCCCCEEE
RADGRFEGIDIDMAESLAKSLGVKTDYVKTSWPNLTGDFVAKCDIAVGGVSTTLERQKRV
ECCCEEECCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHCE
FFTQPYVVDGKTPIVRCADADKYQTVAQIDRPETRVIVNPGGTNERFAKQYFTHANLTVY
EEECCEEECCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEE
PDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRGDVAF
CCCHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCCEECCCCCCCCCCCEEEECCCCCHHH
QQYVDQWLHLALSTGEYQAISDKWLK
HHHHHHHHHHHHCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]