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The map label for this gene is qseC [H]

Identifier: 78064732

GI number: 78064732

Start: 89213

End: 90697

Strand: Reverse

Name: qseC [H]

Synonym: Bcep18194_A3255

Alternate gene names: 78064732

Gene position: 90697-89213 (Counterclockwise)

Preceding gene: 78064733

Following gene: 78064724

Centisome position: 2.46

GC content: 69.9

Gene sequence:

>1485_bases
ATGTCTCCTGATCCGGCTGTGACCACCAGCCTGCGCCGCTCGCTGCTCCGGCGCCTCGCCGCCCCGCTGTCGATGCTCGC
GCTGATGAGCGGCCTGATCGCCTACTGGCTCGCGTGGCAGTACACGCAGCACGTGATCGACCGCTCGCTCGCCGATCTCG
CGACCGCCATCTCCAAACAGATCCAGATCGCCGGCCCCGACGCGCCGTTCACGGTGCCGCCGCTCGCGCAGGCGATGTTC
TCCGATCCCGCCGAAGCACTGATCTACCGGATCAGCGACGGCGAGCAGGAACTCGCCGGCGATCCGAAGCTGCCGCTGCA
GGGCATCAACGTGCGCCGCATGCATCACGCGTACGTGTTCGAGGCCGAATACGACAACCGCGCGGTACGGGTTGCGCAGG
TGCGCGTCGACGACGTCGACGGCGGCAAGCCGATGGTCGTCGAGGTCGCGCAGCCGGTGCGGCACCGCTACCGGATCGCG
GCCGAATTCCTCGTCGCGATCATGATGCCGCTGCTGCTGCTGCTGCTCGCGGGCTGGGGCATCGTGTGGCGCGTCGTGAA
CCAGCAGCTCGGCCCGCTCACGCACCTGGCCGATTCGCTGAACCGGCAGACCCACACGTCGCTGGAACCGGTCGACGAAA
CCGAGGTGCCGCTGGAAATCCGGCCGCTGACGAGCGCGATGAACGCGCTGCTCGGCCGCCTGAAGACTGCCCTCGACGCG
CAGCGCAAGTTCATCGCCGATGCCGCCCACCAGTTGCGCACGCCGCTCACGGCCGTGAAGCTGCATGCGGAGCAAGCGGC
CGTTGCGCGCGACCCGCACCAGACCTTTGCCGCGGTGCGCGAACTGCGCGCGGCCGCCGACCGCGCGGTACGGCTGTCCA
ACCAGTTGCTGTCGCTCGCCCGTGCGGAACCGGGCGAACAGGCCGCGCGGTTCGTCGACGTCGACCTCGCGGCGATGGCG
TTCGAGACGGGCGCCGAATGGGTGCCGCGCGCCCTCGCATCGCACGTCGACCTCGGCTTCCAGCGCACCGACGATCCCGG
TGACGACGAGAAGCTGGTCGTACGCGGCAACCCTGTGCTGCTGCGCGAGGTGATCGCGAACCTGCTCGACAATGCGCTGA
AGTACGTGCCGCTCGCACGGCCGGACGGCGCGCGGATCACGGTGAACGTCGCGCGCGGCGCGCTCGAGGACGGCCAGCCG
GCCGCCGAGATCGTCGTCGAGGACAACGGCCCCGGCGTGCCCGCCAACCAGCAGGCCGACCTGTTCAAGCGCTTCTTCCG
CGGCGACGCGCAAAGCGGCAATGGCGTCGAGACGGGCGCCGGGCTCGGCCTCGCGATCGTGCACGACATCATCGCGATAC
ACGGCGGCACCGTCTCGTACGAGGATGCATCGGAAGGCGGTTCGCGCTTCGTGGTGAGAGTGCCGCTGGTCGCGCGCACC
GAGAAGCCGGCCAGCGAAACACCGGCCGCCGCGTCGACGCACTGA

Upstream 100 bases:

>100_bases
CGGCCACGTGCCGCCCGCGTGTGCACGCTGCTCCGCGTCGCCGCCCGGCGCAAGACCGCGCCGCTCCCCGTGAGCGGCGC
TTATCCATTTGCCCGTCGAA

Downstream 100 bases:

>100_bases
GGGACGGAGAGACTCACGGCGGGCGGCCGCTGATCGGGCCGCGCGCCGGATGAGGAAGGCGGACAGCACGGCTGCACGAT
GCGGCAGCCGTCTGCTGAAA

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSPDPAVTTSLRRSLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVIDRSLADLATAISKQIQIAGPDAPFTVPPLAQAMF
SDPAEALIYRISDGEQELAGDPKLPLQGINVRRMHHAYVFEAEYDNRAVRVAQVRVDDVDGGKPMVVEVAQPVRHRYRIA
AEFLVAIMMPLLLLLLAGWGIVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETEVPLEIRPLTSAMNALLGRLKTALDA
QRKFIADAAHQLRTPLTAVKLHAEQAAVARDPHQTFAAVRELRAAADRAVRLSNQLLSLARAEPGEQAARFVDVDLAAMA
FETGAEWVPRALASHVDLGFQRTDDPGDDEKLVVRGNPVLLREVIANLLDNALKYVPLARPDGARITVNVARGALEDGQP
AAEIVVEDNGPGVPANQQADLFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAIHGGTVSYEDASEGGSRFVVRVPLVART
EKPASETPAAASTH

Sequences:

>Translated_494_residues
MSPDPAVTTSLRRSLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVIDRSLADLATAISKQIQIAGPDAPFTVPPLAQAMF
SDPAEALIYRISDGEQELAGDPKLPLQGINVRRMHHAYVFEAEYDNRAVRVAQVRVDDVDGGKPMVVEVAQPVRHRYRIA
AEFLVAIMMPLLLLLLAGWGIVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETEVPLEIRPLTSAMNALLGRLKTALDA
QRKFIADAAHQLRTPLTAVKLHAEQAAVARDPHQTFAAVRELRAAADRAVRLSNQLLSLARAEPGEQAARFVDVDLAAMA
FETGAEWVPRALASHVDLGFQRTDDPGDDEKLVVRGNPVLLREVIANLLDNALKYVPLARPDGARITVNVARGALEDGQP
AAEIVVEDNGPGVPANQQADLFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAIHGGTVSYEDASEGGSRFVVRVPLVART
EKPASETPAAASTH
>Mature_493_residues
SPDPAVTTSLRRSLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVIDRSLADLATAISKQIQIAGPDAPFTVPPLAQAMFS
DPAEALIYRISDGEQELAGDPKLPLQGINVRRMHHAYVFEAEYDNRAVRVAQVRVDDVDGGKPMVVEVAQPVRHRYRIAA
EFLVAIMMPLLLLLLAGWGIVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETEVPLEIRPLTSAMNALLGRLKTALDAQ
RKFIADAAHQLRTPLTAVKLHAEQAAVARDPHQTFAAVRELRAAADRAVRLSNQLLSLARAEPGEQAARFVDVDLAAMAF
ETGAEWVPRALASHVDLGFQRTDDPGDDEKLVVRGNPVLLREVIANLLDNALKYVPLARPDGARITVNVARGALEDGQPA
AEIVVEDNGPGVPANQQADLFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAIHGGTVSYEDASEGGSRFVVRVPLVARTE
KPASETPAAASTH

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=470, Percent_Identity=28.2978723404255, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1790551, Length=323, Percent_Identity=31.5789473684211, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786783, Length=342, Percent_Identity=26.6081871345029, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1786600, Length=282, Percent_Identity=31.9148936170213, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790346, Length=271, Percent_Identity=27.6752767527675, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=293, Percent_Identity=27.3037542662116, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=31.0204081632653, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=260, Percent_Identity=25, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789149, Length=250, Percent_Identity=27.6, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=27.9835390946502, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787894, Length=268, Percent_Identity=28.7313432835821, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=26.7558528428094, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789808, Length=328, Percent_Identity=25.3048780487805, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=28.740157480315, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=328, Percent_Identity=27.1341463414634, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=26.6949152542373, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081816, Length=368, Percent_Identity=26.3586956521739, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53502; Mature: 53371

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDPAVTTSLRRSLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVIDRSLADLATAISKQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IQIAGPDAPFTVPPLAQAMFSDPAEALIYRISDGEQELAGDPKLPLQGINVRRMHHAYVF
EEEECCCCCCCCCHHHHHHHCCCHHHEEEEECCCCHHHCCCCCCCCCCCCCEEEEEEEEE
EAEYDNRAVRVAQVRVDDVDGGKPMVVEVAQPVRHRYRIAAEFLVAIMMPLLLLLLAGWG
EEECCCCEEEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETEVPLEIRPLTSAMNALLGRLKTALDA
HHHHHHHHHHCHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
QRKFIADAAHQLRTPLTAVKLHAEQAAVARDPHQTFAAVRELRAAADRAVRLSNQLLSLA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEPGEQAARFVDVDLAAMAFETGAEWVPRALASHVDLGFQRTDDPGDDEKLVVRGNPVL
HCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHH
LREVIANLLDNALKYVPLARPDGARITVNVARGALEDGQPAAEIVVEDNGPGVPANQQAD
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCHHH
LFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAIHGGTVSYEDASEGGSRFVVRVPLVART
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCEECC
EKPASETPAAASTH
CCCCCCCCCCCCCC
>Mature Secondary Structure 
SPDPAVTTSLRRSLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVIDRSLADLATAISKQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IQIAGPDAPFTVPPLAQAMFSDPAEALIYRISDGEQELAGDPKLPLQGINVRRMHHAYVF
EEEECCCCCCCCCHHHHHHHCCCHHHEEEEECCCCHHHCCCCCCCCCCCCCEEEEEEEEE
EAEYDNRAVRVAQVRVDDVDGGKPMVVEVAQPVRHRYRIAAEFLVAIMMPLLLLLLAGWG
EEECCCCEEEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETEVPLEIRPLTSAMNALLGRLKTALDA
HHHHHHHHHHCHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
QRKFIADAAHQLRTPLTAVKLHAEQAAVARDPHQTFAAVRELRAAADRAVRLSNQLLSLA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEPGEQAARFVDVDLAAMAFETGAEWVPRALASHVDLGFQRTDDPGDDEKLVVRGNPVL
HCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHH
LREVIANLLDNALKYVPLARPDGARITVNVARGALEDGQPAAEIVVEDNGPGVPANQQAD
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCHHH
LFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAIHGGTVSYEDASEGGSRFVVRVPLVART
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCEECC
EKPASETPAAASTH
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]