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The map label for this gene is marR [H]

Identifier: 78064707

GI number: 78064707

Start: 62644

End: 63135

Strand: Reverse

Name: marR [H]

Synonym: Bcep18194_A3230

Alternate gene names: 78064707

Gene position: 63135-62644 (Counterclockwise)

Preceding gene: 78064710

Following gene: 78064706

Centisome position: 1.71

GC content: 67.68

Gene sequence:

>492_bases
ATGACCGGCGGCCTCTACGATCCCGAGAACATCGAGCTGGAAACGAGCCTCGGCTATTACCTGTCGAAGGCGAAGCAGGC
GCTCGTCGAGCGGATGGACCGTGCGCTCGAGCCGCTCGACCTCACCGCGCAGCAGATCGGCGTGATCCTGCTGCTGTCGC
GCGGCTATGCGCGCACGCCGTTCGAGCTTTCCCGCAAGATGTCGTACGACAGCGGTTCGATGACGCGGATGCTCGACCGG
CTCGAACGCAAGGGGCTGGTCGCCCGCTCGCGCAGCGAGCAGGACCGCCGCATGATCGAGCTGACGTTGACCGAACGCGG
CGCCGAAGCCGCCCGGGCGCTGCCGTCGCTGATCGCCACCGCGCTCAACGCGCAGCTCGACGGTTTCTCGGCCGACGAGC
TTGTGACGCTCACCGGCCTGCTGCAGCGCTTCATCGCCAACGGGCCCGGCTCGACCGGTTGCCCGAAACCCGACGACGAA
GCGGATTGCTGA

Upstream 100 bases:

>100_bases
TCGTAACTGGTTGCCTCAAATAATATTGACTAAGCAATCAATTTTCAAGATACTGGGCGCGTTTAAATCTGAAACGCACT
ATTGCTGCGCGCGCAATCGA

Downstream 100 bases:

>100_bases
TGTGCGCGGAGGCCCCATGTCTAGGTTAAGCATTCGCTTATTTATCTGTCTGGGCAGAAGATGACAGGGCACGCGCTCCC
TTTTTCCGTTTATCCGTTCC

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MTGGLYDPENIELETSLGYYLSKAKQALVERMDRALEPLDLTAQQIGVILLLSRGYARTPFELSRKMSYDSGSMTRMLDR
LERKGLVARSRSEQDRRMIELTLTERGAEAARALPSLIATALNAQLDGFSADELVTLTGLLQRFIANGPGSTGCPKPDDE
ADC

Sequences:

>Translated_163_residues
MTGGLYDPENIELETSLGYYLSKAKQALVERMDRALEPLDLTAQQIGVILLLSRGYARTPFELSRKMSYDSGSMTRMLDR
LERKGLVARSRSEQDRRMIELTLTERGAEAARALPSLIATALNAQLDGFSADELVTLTGLLQRFIANGPGSTGCPKPDDE
ADC
>Mature_162_residues
TGGLYDPENIELETSLGYYLSKAKQALVERMDRALEPLDLTAQQIGVILLLSRGYARTPFELSRKMSYDSGSMTRMLDRL
ERKGLVARSRSEQDRRMIELTLTERGAEAARALPSLIATALNAQLDGFSADELVTLTGLLQRFIANGPGSTGCPKPDDEA
DC

Specific function: Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081927, Length=130, Percent_Identity=34.6153846153846, Blast_Score=72, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17929; Mature: 17797

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGLYDPENIELETSLGYYLSKAKQALVERMDRALEPLDLTAQQIGVILLLSRGYARTP
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCC
FELSRKMSYDSGSMTRMLDRLERKGLVARSRSEQDRRMIELTLTERGAEAARALPSLIAT
HHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHEEHHHHHHCCHHHHHHHHHHHHH
ALNAQLDGFSADELVTLTGLLQRFIANGPGSTGCPKPDDEADC
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGGLYDPENIELETSLGYYLSKAKQALVERMDRALEPLDLTAQQIGVILLLSRGYARTP
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCC
FELSRKMSYDSGSMTRMLDRLERKGLVARSRSEQDRRMIELTLTERGAEAARALPSLIAT
HHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHEEHHHHHHCCHHHHHHHHHHHHH
ALNAQLDGFSADELVTLTGLLQRFIANGPGSTGCPKPDDEADC
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 8282690; 7768850; 10760140 [H]