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The map label for this gene is gltD

Identifier: 161702971

GI number: 161702971

Start: 367730

End: 369196

Strand: Direct

Name: gltD

Synonym: Bcep18194_A3500

Alternate gene names: 161702971

Gene position: 367730-369196 (Clockwise)

Preceding gene: 78064976

Following gene: 78064978

Centisome position: 9.95

GC content: 65.78

Gene sequence:

>1467_bases
ATGGGCAAGGCAACCGGTTTTCTGGAGTTCGAACGCCGCCACGAGGCGTACGAAGCACCGCTCACGCGCGTGAAGCACTA
CAAGGAATTCGTCGCGGCACTGACCGACGCGGACGCGAAGGTCCAGGGCGCGCGCTGCATGGATTGCGGCATCCCGTTCT
GCAACAACGGCTGCCCGGTCAACAACATCATTCCTGACTTCAACGATCTCGTTTACCGCCAGGACTGGCAGCAGGCGATC
GAAGTCCTGCATTCGACCAACAACTTCCCGGAATTCACGGGCCGCATCTGCCCGGCGCCGTGCGAAGCAGCCTGCACGCT
CGGGATCAACAACGACCCGGTCGGCATCAAGTCGATCGAGCACGCGATCATCGACAAGGCCTGGGCGGAAGGCTGGGTGA
AGCCGCTGCCGGCCGAGCACAAGACGGGCAAGAAGGTCGCGGTCGTCGGCTCGGGCCCCGCGGGCCTCGCCGCCGCGCAG
CAGCTCGCTCGCGCGGGCCACGACGTGACGGTGTTCGAGAAGAACGACCGTGTCGGCGGCCTGCTGCGTTACGGGATTCC
CGACTTCAAGCTCGAGAAGTGGCTGATCGACCGCCGCATGCGCCAGATGGAAGCGGAAGGCGTGACGTTCCGGACCAGCG
TGTTCATCGGCAAGGATCCGCTGCCCGAGTCGATCGGCAGCCTCGCGAAGGAGACCATCTCGCCGGAGACGCTGAAGGAA
GAATTCGACGCGGTCGTGATCGCGGGCGGTTCGGAAACGCCGCGCGACCTGCCGGTGCCGGGCCGCGAACTCGCGGGCGT
TCACTATGCGATGGACTTCCTGCCGCAGCAGAACCGCGTGAACGCGGGCGACAAGCTCGTCGACCAGCTGCTCGCGAAGG
GCAAGCACGTGATCGTGATCGGCGGTGGCGACACCGGTTCGGACTGCGTCGGCACGTCGAACCGTCACGGTGCGAAGCAG
GTCACGCAGTTCGAGCTGCTGCCGCAGCCGCCGGAAGAGGAAAACAAGCCGCTCGTGTGGCCGTACTGGCCGATCAAGCT
GCGCACGTCGTCGTCGCATGACGAAGGTTGCGAGCGCGACTGGGCAGTCGCGACGAAGCGTCTCGAAGGCAAGAACGGCA
AGGTCGAGAAGCTGATCGCGGTGCGCGTCGAGTGGAAGGACGGCAAGATGCAGGAAGTGCCGGGCTCCGAGTTCGAAATG
AAGGCCGACCTCGTGCTGCTCGCGATGGGCTTCACGCAGCCGGCGGCACCCGTGCTCGAGGCATTCGGCGTCGCGAAGGA
TGCGCGCGGCAATGCGCGTGCGGCGACCGAAGGCGATCGTTCGTACTACACGTCGGTCGACAAGGTGTTCGCGGCGGGCG
ACATGCGCCGCGGCCAGTCGCTCGTGGTGTGGGCGATCCGCGAAGGCCGCCAGTGCGCGCGCTCGGTCGATGCGTACCTG
ATGGGGCATTCGAACCTGCCGCGATAA

Upstream 100 bases:

>100_bases
GAACTGGCCGCCTGAGCGACGAACGACATAGCGAATGCCGCGCGCGCATGATTGCCGCGCGCGGCTCCCCCACCCGATAC
ACCGAACAGAAGAGCACCTT

Downstream 100 bases:

>100_bases
GCGCGGGGCGGTAACCGTCGTCGAAACCGGGCGTCCGAAAGGGCGCCCGGTTTTTTTTGCGCGCGCGATTCGGTGATGCG
CCGTGCGTGCGCTGCGCGTT

Product: glutamate synthase subunit beta

Products: NA

Alternate protein names: NADPH-GOGAT [H]

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MGKATGFLEFERRHEAYEAPLTRVKHYKEFVAALTDADAKVQGARCMDCGIPFCNNGCPVNNIIPDFNDLVYRQDWQQAI
EVLHSTNNFPEFTGRICPAPCEAACTLGINNDPVGIKSIEHAIIDKAWAEGWVKPLPAEHKTGKKVAVVGSGPAGLAAAQ
QLARAGHDVTVFEKNDRVGGLLRYGIPDFKLEKWLIDRRMRQMEAEGVTFRTSVFIGKDPLPESIGSLAKETISPETLKE
EFDAVVIAGGSETPRDLPVPGRELAGVHYAMDFLPQQNRVNAGDKLVDQLLAKGKHVIVIGGGDTGSDCVGTSNRHGAKQ
VTQFELLPQPPEEENKPLVWPYWPIKLRTSSSHDEGCERDWAVATKRLEGKNGKVEKLIAVRVEWKDGKMQEVPGSEFEM
KADLVLLAMGFTQPAAPVLEAFGVAKDARGNARAATEGDRSYYTSVDKVFAAGDMRRGQSLVVWAIREGRQCARSVDAYL
MGHSNLPR

Sequences:

>Translated_488_residues
MGKATGFLEFERRHEAYEAPLTRVKHYKEFVAALTDADAKVQGARCMDCGIPFCNNGCPVNNIIPDFNDLVYRQDWQQAI
EVLHSTNNFPEFTGRICPAPCEAACTLGINNDPVGIKSIEHAIIDKAWAEGWVKPLPAEHKTGKKVAVVGSGPAGLAAAQ
QLARAGHDVTVFEKNDRVGGLLRYGIPDFKLEKWLIDRRMRQMEAEGVTFRTSVFIGKDPLPESIGSLAKETISPETLKE
EFDAVVIAGGSETPRDLPVPGRELAGVHYAMDFLPQQNRVNAGDKLVDQLLAKGKHVIVIGGGDTGSDCVGTSNRHGAKQ
VTQFELLPQPPEEENKPLVWPYWPIKLRTSSSHDEGCERDWAVATKRLEGKNGKVEKLIAVRVEWKDGKMQEVPGSEFEM
KADLVLLAMGFTQPAAPVLEAFGVAKDARGNARAATEGDRSYYTSVDKVFAAGDMRRGQSLVVWAIREGRQCARSVDAYL
MGHSNLPR
>Mature_487_residues
GKATGFLEFERRHEAYEAPLTRVKHYKEFVAALTDADAKVQGARCMDCGIPFCNNGCPVNNIIPDFNDLVYRQDWQQAIE
VLHSTNNFPEFTGRICPAPCEAACTLGINNDPVGIKSIEHAIIDKAWAEGWVKPLPAEHKTGKKVAVVGSGPAGLAAAQQ
LARAGHDVTVFEKNDRVGGLLRYGIPDFKLEKWLIDRRMRQMEAEGVTFRTSVFIGKDPLPESIGSLAKETISPETLKEE
FDAVVIAGGSETPRDLPVPGRELAGVHYAMDFLPQQNRVNAGDKLVDQLLAKGKHVIVIGGGDTGSDCVGTSNRHGAKQV
TQFELLPQPPEEENKPLVWPYWPIKLRTSSSHDEGCERDWAVATKRLEGKNGKVEKLIAVRVEWKDGKMQEVPGSEFEMK
ADLVLLAMGFTQPAAPVLEAFGVAKDARGNARAATEGDRSYYTSVDKVFAAGDMRRGQSLVVWAIREGRQCARSVDAYLM
GHSNLPR

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamate synthase family [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=493, Percent_Identity=26.7748478701826, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1788811, Length=467, Percent_Identity=35.5460385438972, Blast_Score=244, Evalue=9e-66,
Organism=Escherichia coli, GI1789606, Length=486, Percent_Identity=33.9506172839506, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI87082180, Length=467, Percent_Identity=33.6188436830835, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI1788468, Length=463, Percent_Identity=29.1576673866091, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1789243, Length=444, Percent_Identity=28.3783783783784, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17570289, Length=506, Percent_Identity=45.8498023715415, Blast_Score=429, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI71984108, Length=490, Percent_Identity=26.1224489795918, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320030, Length=502, Percent_Identity=49.800796812749, Blast_Score=472, Evalue=1e-134,
Organism=Drosophila melanogaster, GI28574881, Length=503, Percent_Identity=50.0994035785288, Blast_Score=474, Evalue=1e-134,
Organism=Drosophila melanogaster, GI24665539, Length=503, Percent_Identity=50.0994035785288, Blast_Score=474, Evalue=1e-134,
Organism=Drosophila melanogaster, GI24665547, Length=503, Percent_Identity=50.0994035785288, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24665543, Length=503, Percent_Identity=50.0994035785288, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24640763, Length=487, Percent_Identity=25.0513347022587, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI18858217, Length=487, Percent_Identity=25.0513347022587, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006005
- InterPro:   IPR009051
- InterPro:   IPR016040
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 53573; Mature: 53442

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKATGFLEFERRHEAYEAPLTRVKHYKEFVAALTDADAKVQGARCMDCGIPFCNNGCPV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
NNIIPDFNDLVYRQDWQQAIEVLHSTNNFPEFTGRICPAPCEAACTLGINNDPVGIKSIE
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCEEEECCCCCCCCHHHHH
HAIIDKAWAEGWVKPLPAEHKTGKKVAVVGSGPAGLAAAQQLARAGHDVTVFEKNDRVGG
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCC
LLRYGIPDFKLEKWLIDRRMRQMEAEGVTFRTSVFIGKDPLPESIGSLAKETISPETLKE
EEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCHHHHHH
EFDAVVIAGGSETPRDLPVPGRELAGVHYAMDFLPQQNRVNAGDKLVDQLLAKGKHVIVI
HCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEE
GGGDTGSDCVGTSNRHGAKQVTQFELLPQPPEEENKPLVWPYWPIKLRTSSSHDEGCERD
ECCCCCCCCCCCCCCCCHHHHHHEECCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCHH
WAVATKRLEGKNGKVEKLIAVRVEWKDGKMQEVPGSEFEMKADLVLLAMGFTQPAAPVLE
HHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEECCEEEEEECCCCCHHHHHH
AFGVAKDARGNARAATEGDRSYYTSVDKVFAAGDMRRGQSLVVWAIREGRQCARSVDAYL
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHH
MGHSNLPR
CCCCCCCC
>Mature Secondary Structure 
GKATGFLEFERRHEAYEAPLTRVKHYKEFVAALTDADAKVQGARCMDCGIPFCNNGCPV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
NNIIPDFNDLVYRQDWQQAIEVLHSTNNFPEFTGRICPAPCEAACTLGINNDPVGIKSIE
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCEEEECCCCCCCCHHHHH
HAIIDKAWAEGWVKPLPAEHKTGKKVAVVGSGPAGLAAAQQLARAGHDVTVFEKNDRVGG
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCC
LLRYGIPDFKLEKWLIDRRMRQMEAEGVTFRTSVFIGKDPLPESIGSLAKETISPETLKE
EEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCHHHHHH
EFDAVVIAGGSETPRDLPVPGRELAGVHYAMDFLPQQNRVNAGDKLVDQLLAKGKHVIVI
HCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEE
GGGDTGSDCVGTSNRHGAKQVTQFELLPQPPEEENKPLVWPYWPIKLRTSSSHDEGCERD
ECCCCCCCCCCCCCCCCHHHHHHEECCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCHH
WAVATKRLEGKNGKVEKLIAVRVEWKDGKMQEVPGSEFEMKADLVLLAMGFTQPAAPVLE
HHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEECCEEEEEECCCCCHHHHHH
AFGVAKDARGNARAATEGDRSYYTSVDKVFAAGDMRRGQSLVVWAIREGRQCARSVDAYL
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHH
MGHSNLPR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11029411 [H]