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The map label for this gene is murA

Identifier: 161702970

GI number: 161702970

Start: 387618

End: 388880

Strand: Direct

Name: murA

Synonym: Bcep18194_A3521

Alternate gene names: 161702970

Gene position: 387618-388880 (Clockwise)

Preceding gene: 78064997

Following gene: 78064999

Centisome position: 10.49

GC content: 67.7

Gene sequence:

>1263_bases
ATGGACAAGCTCGTGATCGAAGGCGGCCACCGCCTGTCGGGCGAGATCGTCGTGTCGGGCGCGAAGAATGCCGCGCTGCC
GATCCTGTGCGCGGGGCTGCTCACCGGGGATCCGGTCGATCTCGACAACGTGCCGAATCTCAAGGACGTGCGTACCACGC
TGAAGGTGCTGAACCAGATGGGCGTGAAGAGCGAGACGGACGGCTGCCGCGTGCAGCTCGACGCGTCGCGCGTCGACAAC
CTCGTCGCGCCGTACGAGCTCGTGAAGACGATGCGTGCGTCGATCCTCGTGCTCGGGCCGCTGCTCGCACGCTTCGGCGA
GGCGAAGGTGTCGCTGCCGGGCGGCTGCGCGATCGGCGCGCGTCCGGTCGACCAGCACATCAAGGGCCTGCAGGCGATGG
GCGCCGAGATCAGCATCGAGCACGGCTTCATCGAAGCCCGCGCGAAGCGCCTGAAGGGCGCGCGCATCGTGACCGACATG
ATCACGGTGACGGGCACGGAAAACCTGCTGATGGCCGCGACGCTCGCCGATGGCGAGACGGTGATCGAAAACGCCGCGCG
CGAGCCGGAAGTGAGCGATCTCGCACACTTGCTGGTCGCGATGGGCGCGAAAATCGACGGCATCGGCACCGATCGCCTCG
TGATCCAGGGCGTCGAGCGGCTGCACGGCGCGCGCCATTCGGTGATCCCCGACCGCATCGAGGCCGGCACGTTCCTGTGC
GCGGTCGCGGCGGCCGGCGGCGACGTGAGGCTGACGGGCGTGCGCCCGCACATCCTCGATGCGGTGATCGACAAGCTGCG
CGAAGCCGGCGTGTCGATCGAGGAAGGCGACAGCTGGCTGCGCGTGAAGATGGACCGCCGGCCGTCGGCGGTGACGATCC
GCACGTCGGAATACCCGGCGTTCCCGACCGACATGCAGGCGCAGTTCATGGCCCTCAATACGGTCGCGACGGGCACCGCG
CAGGTCGTCGAAACCATTTTCGAGAACCGTTTCATGCACGTGCAGGAGCTGAACCGGCTCGGCGCGAACATCACGATCGA
CGGCAACACCGCGCTCGTGACGGGTGTGGACAAGCTGTCGGGCGCGAACGTGATGGCGACCGACCTGCGTGCGTCGGCGA
GCCTCGTGATCGCCGGGCTGCGTGCCGAAGGCGAAACGCTGGTCGACCGCATCTATCACCTGGACCGCGGCTACGACCGC
ATGGAAGCCAAACTGACCGCCGTCGGCGCGAACGTGCGCCGACTTTCCGGGAGCCAAGCATGA

Upstream 100 bases:

>100_bases
CGGAAATCACTGAGTGCAAGTCACCGTCAACGAGCGCGACGCGGTCCAGAGCGTCGCCACGGCACACCCGGCCGCCAACG
GGGAATCGCATGGCCATGGG

Downstream 100 bases:

>100_bases
CCGCGCCGCTGACCCTTGCCCTGTCGAAGGGCCGGATTTTCGAGGAAACCCTGCCGTTGCTGGCCGCGGCCGGCGTGCAG
GTCACCGAGGATCCGGAAAC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MDKLVIEGGHRLSGEIVVSGAKNAALPILCAGLLTGDPVDLDNVPNLKDVRTTLKVLNQMGVKSETDGCRVQLDASRVDN
LVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEISIEHGFIEARAKRLKGARIVTDM
ITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTDRLVIQGVERLHGARHSVIPDRIEAGTFLC
AVAAAGGDVRLTGVRPHILDAVIDKLREAGVSIEEGDSWLRVKMDRRPSAVTIRTSEYPAFPTDMQAQFMALNTVATGTA
QVVETIFENRFMHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRASASLVIAGLRAEGETLVDRIYHLDRGYDR
MEAKLTAVGANVRRLSGSQA

Sequences:

>Translated_420_residues
MDKLVIEGGHRLSGEIVVSGAKNAALPILCAGLLTGDPVDLDNVPNLKDVRTTLKVLNQMGVKSETDGCRVQLDASRVDN
LVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEISIEHGFIEARAKRLKGARIVTDM
ITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTDRLVIQGVERLHGARHSVIPDRIEAGTFLC
AVAAAGGDVRLTGVRPHILDAVIDKLREAGVSIEEGDSWLRVKMDRRPSAVTIRTSEYPAFPTDMQAQFMALNTVATGTA
QVVETIFENRFMHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRASASLVIAGLRAEGETLVDRIYHLDRGYDR
MEAKLTAVGANVRRLSGSQA
>Mature_420_residues
MDKLVIEGGHRLSGEIVVSGAKNAALPILCAGLLTGDPVDLDNVPNLKDVRTTLKVLNQMGVKSETDGCRVQLDASRVDN
LVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEISIEHGFIEARAKRLKGARIVTDM
ITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTDRLVIQGVERLHGARHSVIPDRIEAGTFLC
AVAAAGGDVRLTGVRPHILDAVIDKLREAGVSIEEGDSWLRVKMDRRPSAVTIRTSEYPAFPTDMQAQFMALNTVATGTA
QVVETIFENRFMHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRASASLVIAGLRAEGETLVDRIYHLDRGYDR
MEAKLTAVGANVRRLSGSQA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=58.9498806682578, Blast_Score=496, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_BURS3 (Q39K93)

Other databases:

- EMBL:   CP000151
- RefSeq:   YP_367767.2
- ProteinModelPortal:   Q39K93
- SMR:   Q39K93
- STRING:   Q39K93
- GeneID:   3748698
- GenomeReviews:   CP000151_GR
- KEGG:   bur:Bcep18194_A3521
- NMPDR:   fig|269483.3.peg.4825
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   BSP36773:BCEP18194_A3521-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44713; Mature: 44713

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: ACT_SITE 145-145

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLVIEGGHRLSGEIVVSGAKNAALPILCAGLLTGDPVDLDNVPNLKDVRTTLKVLNQM
CCCEEEECCCEECCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GVKSETDGCRVQLDASRVDNLVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGA
CCCCCCCCCEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
RPVDQHIKGLQAMGAEISIEHGFIEARAKRLKGARIVTDMITVTGTENLLMAATLADGET
CCHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEEECCCHH
VIENAAREPEVSDLAHLLVAMGAKIDGIGTDRLVIQGVERLHGARHSVIPDRIEAGTFLC
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHCCCCEEE
AVAAAGGDVRLTGVRPHILDAVIDKLREAGVSIEEGDSWLRVKMDRRPSAVTIRTSEYPA
EEEECCCCEEEECCCHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCEEEEECCCCCC
FPTDMQAQFMALNTVATGTAQVVETIFENRFMHVQELNRLGANITIDGNTALVTGVDKLS
CCCCCCHHEEEEHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCEEEEEECHHHC
GANVMATDLRASASLVIAGLRAEGETLVDRIYHLDRGYDRMEAKLTAVGANVRRLSGSQA
CCCEEEEHHHCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure
MDKLVIEGGHRLSGEIVVSGAKNAALPILCAGLLTGDPVDLDNVPNLKDVRTTLKVLNQM
CCCEEEECCCEECCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GVKSETDGCRVQLDASRVDNLVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGA
CCCCCCCCCEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
RPVDQHIKGLQAMGAEISIEHGFIEARAKRLKGARIVTDMITVTGTENLLMAATLADGET
CCHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEEECCCHH
VIENAAREPEVSDLAHLLVAMGAKIDGIGTDRLVIQGVERLHGARHSVIPDRIEAGTFLC
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHCCCCEEE
AVAAAGGDVRLTGVRPHILDAVIDKLREAGVSIEEGDSWLRVKMDRRPSAVTIRTSEYPA
EEEECCCCEEEECCCHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCEEEEECCCCCC
FPTDMQAQFMALNTVATGTAQVVETIFENRFMHVQELNRLGANITIDGNTALVTGVDKLS
CCCCCCHHEEEEHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCEEEEEECHHHC
GANVMATDLRASASLVIAGLRAEGETLVDRIYHLDRGYDRMEAKLTAVGANVRRLSGSQA
CCCEEEEHHHCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA