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The map label for this gene is pheS

Identifier: 161702961

GI number: 161702961

Start: 1600790

End: 1601812

Strand: Direct

Name: pheS

Synonym: Bcep18194_A4619

Alternate gene names: 161702961

Gene position: 1600790-1601812 (Clockwise)

Preceding gene: 78066089

Following gene: 78066091

Centisome position: 43.33

GC content: 62.17

Gene sequence:

>1023_bases
ATGGGATCTATGGATCTGGACCAGATTGTCGCCGACGCGCAGCAGTCCTTCGAACAGGCTGCCGACATCACCACGCTCGA
AAACGAGAAAGCACGATTTCTCGGCAAGTCGGGTGCGCTGACCGAGTTGCTGAAGGGCCTCGGCAAGCTCGATCCCGAAG
CACGCAAGACCGAAGGTGCACGCATCAATGTCGTGAAGCAGCAGGTTGAAGCCGCGCTGACCGCCCGTCGCCAGGCACTG
GCCGACGCGCTGCTGAATCAGCGCCTCACTGCCGAAGCGATCGACGTGACGTTGCCGGGTCGCGGCGCCGGTGCAGGCAG
CCTGCACCCCGTGATGCGCACGTGGGAGCGTGTCGAACAGATTTTCGGCTCGATCGGTTTCGATGTGGCCGACGGCCCCG
AAATCGAGACCGACTGGTACAACTTCACGTCGCTGAACAGCCCGGAGAACCATCCGGCGCGTTCGATGCAGGACACCTTC
TACGTCGAAGGCAAGGATGCCGACGGCCGCCAGCTGCTGCTGCGCACGCACACGAGCCCGATGCAGGTGCGTTACGCGCG
CATGAACCGTCCGCCGATCAAGGTGATCGCGCCGGGCCGCACGTATCGCGTCGACAGCGATGCGACCCACTCGCCGATGT
TCAATCAGGTCGAGGGGCTGTGGATCGACGAAAACATCAGCTTCGCCGACCTCAAGGGCGTCTATACCGACTTCCTGAAA
AAATTCTTCGAGCGCGACGACATCCTCGTGCGCTTCCGTCCGTCGTATTTCCCGTTCACGGAACCGTCGGCCGAGATCGA
CATGATGTTCGAGCAAGGCAAGAACGCCGGCAAGTGGCTCGAGATCTCCGGTTCGGGGCAGGTGCATCCGACCGTGATTC
GCAACATGGGCCTCGATCCCGAGCGCTACATCGGCTTTGCGTTTGGCAGCGGCCTCGAGCGCCTGACGATGCTGCGCTAC
GGCGTCCAGGATCTCCGGCTGTTCTTCGAGAACGACCTGCGTTTCCTGCGCCAGTTCGCGTAA

Upstream 100 bases:

>100_bases
CCGGTAGTCTCGGCCGCTGCAGCGAAAACGGGGCTCTTCCGAGCCCCTTTTTTGTTTGGTGGGCGATTTCGCTCGCCAAG
ACCGAATGACGTTGGAAATG

Downstream 100 bases:

>100_bases
CGCCGCGCGCCGCGCCGACCTGTGCCCGTGCACGCCCCGACGGACGATCCGATGGGGCCCGGGCGTCGATCTAACCTGTT
TCGAACGTAGACATCCATGC

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MGSMDLDQIVADAQQSFEQAADITTLENEKARFLGKSGALTELLKGLGKLDPEARKTEGARINVVKQQVEAALTARRQAL
ADALLNQRLTAEAIDVTLPGRGAGAGSLHPVMRTWERVEQIFGSIGFDVADGPEIETDWYNFTSLNSPENHPARSMQDTF
YVEGKDADGRQLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENISFADLKGVYTDFLK
KFFERDDILVRFRPSYFPFTEPSAEIDMMFEQGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERLTMLRY
GVQDLRLFFENDLRFLRQFA

Sequences:

>Translated_340_residues
MGSMDLDQIVADAQQSFEQAADITTLENEKARFLGKSGALTELLKGLGKLDPEARKTEGARINVVKQQVEAALTARRQAL
ADALLNQRLTAEAIDVTLPGRGAGAGSLHPVMRTWERVEQIFGSIGFDVADGPEIETDWYNFTSLNSPENHPARSMQDTF
YVEGKDADGRQLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENISFADLKGVYTDFLK
KFFERDDILVRFRPSYFPFTEPSAEIDMMFEQGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERLTMLRY
GVQDLRLFFENDLRFLRQFA
>Mature_339_residues
GSMDLDQIVADAQQSFEQAADITTLENEKARFLGKSGALTELLKGLGKLDPEARKTEGARINVVKQQVEAALTARRQALA
DALLNQRLTAEAIDVTLPGRGAGAGSLHPVMRTWERVEQIFGSIGFDVADGPEIETDWYNFTSLNSPENHPARSMQDTFY
VEGKDADGRQLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENISFADLKGVYTDFLKK
FFERDDILVRFRPSYFPFTEPSAEIDMMFEQGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERLTMLRYG
VQDLRLFFENDLRFLRQFA

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily

Homologues:

Organism=Homo sapiens, GI4758340, Length=263, Percent_Identity=31.9391634980989, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI5729820, Length=290, Percent_Identity=31.0344827586207, Blast_Score=115, Evalue=8e-26,
Organism=Escherichia coli, GI1788007, Length=334, Percent_Identity=57.185628742515, Blast_Score=384, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI32563657, Length=265, Percent_Identity=33.2075471698113, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17508957, Length=265, Percent_Identity=33.2075471698113, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32566635, Length=249, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321087, Length=267, Percent_Identity=33.3333333333333, Blast_Score=142, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6325304, Length=94, Percent_Identity=40.4255319148936, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI18858079, Length=300, Percent_Identity=30.3333333333333, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI17137424, Length=249, Percent_Identity=29.3172690763052, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFA_BURS3 (Q39H51)

Other databases:

- EMBL:   CP000151
- RefSeq:   YP_368859.2
- ProteinModelPortal:   Q39H51
- SMR:   Q39H51
- STRING:   Q39H51
- GeneID:   3749821
- GenomeReviews:   CP000151_GR
- KEGG:   bur:Bcep18194_A4619
- NMPDR:   fig|269483.3.peg.5939
- eggNOG:   COG0016
- HOGENOM:   HBG284353
- OMA:   FRASYFP
- ProtClustDB:   PRK00488
- BioCyc:   BSP36773:BCEP18194_A4619-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00281
- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978
- PANTHER:   PTHR11538
- TIGRFAMs:   TIGR00468

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d; SSF46589 tRNA_binding_arm

EC number: =6.1.1.20

Molecular weight: Translated: 38353; Mature: 38222

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSMDLDQIVADAQQSFEQAADITTLENEKARFLGKSGALTELLKGLGKLDPEARKTEGA
CCCCCHHHHHHHHHHHHHHHHCCHHCCCCHHHHHCCCCCHHHHHHHHHCCCCHHHHCCCC
RINVVKQQVEAALTARRQALADALLNQRLTAEAIDVTLPGRGAGAGSLHPVMRTWERVEQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHH
IFGSIGFDVADGPEIETDWYNFTSLNSPENHPARSMQDTFYVEGKDADGRQLLLRTHTSP
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCC
MQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENISFADLKGVYTDFLK
HHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHCCCCEEEECCCCHHHHHHHHHHHHH
KFFERDDILVRFRPSYFPFTEPSAEIDMMFEQGKNAGKWLEISGSGQVHPTVIRNMGLDP
HHHCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCH
ERYIGFAFGSGLERLTMLRYGVQDLRLFFENDLRFLRQFA
HHHEEHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSMDLDQIVADAQQSFEQAADITTLENEKARFLGKSGALTELLKGLGKLDPEARKTEGA
CCCCHHHHHHHHHHHHHHHHCCHHCCCCHHHHHCCCCCHHHHHHHHHCCCCHHHHCCCC
RINVVKQQVEAALTARRQALADALLNQRLTAEAIDVTLPGRGAGAGSLHPVMRTWERVEQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHH
IFGSIGFDVADGPEIETDWYNFTSLNSPENHPARSMQDTFYVEGKDADGRQLLLRTHTSP
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCC
MQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENISFADLKGVYTDFLK
HHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHCCCCEEEECCCCHHHHHHHHHHHHH
KFFERDDILVRFRPSYFPFTEPSAEIDMMFEQGKNAGKWLEISGSGQVHPTVIRNMGLDP
HHHCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCH
ERYIGFAFGSGLERLTMLRYGVQDLRLFFENDLRFLRQFA
HHHEEHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA