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The map label for this gene is czcC [H]

Identifier: 78049817

GI number: 78049817

Start: 4893493

End: 4894764

Strand: Reverse

Name: czcC [H]

Synonym: XCV4261

Alternate gene names: 78049817

Gene position: 4894764-4893493 (Counterclockwise)

Preceding gene: 78049818

Following gene: 78049816

Centisome position: 94.52

GC content: 71.86

Gene sequence:

>1272_bases
ATGTGGTTGCGACTGACGGCGCTTGCCGTCTTCGCGGTGGTGCCGTGCGCCAAAGCGCAGGACCTGCCGCCCAAACCCGT
GCTGACCCTGGACGACGCCATTGCACGCGTCGCCCGCCAGCACCCCGATCTGCGCCTGGCCGATGGCCAACGCGCGGTCC
TCAGCGCCGACGCCGAGCGCGACGCACTGCGTCCGCCGTTGCGGATCGGTGCCGAACTGGAAAACGTGTTCGGCACCGGC
CCCACCCGCGCGCTGGACCAGGCCGAACTCACCGTCACCCTGGCCGGCGTGCTGGAACGCGGCGGCAAGCTCGACGCGCG
CCGCACCCTGGCGCAAGCACGTCTCGATGCGCTGGCACCGCAACGCGCCCTGGCCCGGCTGGATGTGCTGGCCGAAGTCG
CGCGGCGTTACCTGGCCATCGGCATGGCCGCGCAGCGGCACGCGGCGGCGCTGGACACGCTGGCCCAGCGCCAGCGCACC
GTCAGTGCTGCGCGCCAACGGCTGCAGGCCGGCGCATCGCCCGAATCGGTGCTGCTGACCGCCCAAGCCCTGCAGGCGCG
CGCAGAACTGGAGCGCGATCGCGCCCAGCAGGAGCTGCTGGCCGCACGGCGCCAGCTGGCGGTGTTGTGGGGCGAGCGCA
CGCCGGACTTCGGCGCCATCACCGGCGACCCGTTGCAGCTGCCGGCGATTCCCGAGTTCGAGGTGCTGGCGCAGCTGCTC
GATGCCACGCCGGAACTGGCGCGCTTGAACGGCGAGCAGCGCGTGCGCGAAGCCCGCGTACGCCTGGCGCGCAGCCAGGC
GCGCCCGGATCTGGACTGGCAGGTGGGCGTGCGCCGGCTCGAAGGCAATGACGCCACTGCATTGCTTGGCAGCGTCTGGC
TGGCATTGGGCAGCGCTGCACGTGCGCAGCCGGAGATTCGCGCCGCCGAAGCGGAGCTGGCGTTGCTGGACATCGAACGT
CAATCGCAGGCGTCGGTGCTCTACGCCACGCTGGCCGATGCGCATGGCCGCTACCGCGCGGCACAGCTGGAAGTGACGCG
CATGCGCGAGGATGTACTGCCGGCGCTCGCACGCGCCGATGCCGCCGCCGAGCGCGCCTATCGCGCCGGCGCCACCAGTT
ATCTGGACTGGGCGCAGCTGCAGGCGCAACGCAGCGATGCACGCCAGCAGCAACTGGCCGCCGCACTGGAAGCACAGACG
GCGCTGATCGAAATCCAGCGTCTGACCGGGCAGCCGTTCGTGCGCGAGCCTGCCGCGCAGGTGACGCCATGA

Upstream 100 bases:

>100_bases
TCGCATCTGAGCGAGACCGGATTGCGTCCTCCGATCGCGGCCTGATGTATCGCCGGCAGCTGCCGGCCTGTCCATCGATC
CCGATTCCGGAGACACCCTC

Downstream 100 bases:

>100_bases
CTGCTGTTTCGCTACTGCGTTTTCATGCCGCGCGTGAGGGCGTTATTGGAATCGCCGCATCTGCAGCGATGTCGGCACCC
AGCGCTCGCCAAACGCTGCC

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MWLRLTALAVFAVVPCAKAQDLPPKPVLTLDDAIARVARQHPDLRLADGQRAVLSADAERDALRPPLRIGAELENVFGTG
PTRALDQAELTVTLAGVLERGGKLDARRTLAQARLDALAPQRALARLDVLAEVARRYLAIGMAAQRHAAALDTLAQRQRT
VSAARQRLQAGASPESVLLTAQALQARAELERDRAQQELLAARRQLAVLWGERTPDFGAITGDPLQLPAIPEFEVLAQLL
DATPELARLNGEQRVREARVRLARSQARPDLDWQVGVRRLEGNDATALLGSVWLALGSAARAQPEIRAAEAELALLDIER
QSQASVLYATLADAHGRYRAAQLEVTRMREDVLPALARADAAAERAYRAGATSYLDWAQLQAQRSDARQQQLAAALEAQT
ALIEIQRLTGQPFVREPAAQVTP

Sequences:

>Translated_423_residues
MWLRLTALAVFAVVPCAKAQDLPPKPVLTLDDAIARVARQHPDLRLADGQRAVLSADAERDALRPPLRIGAELENVFGTG
PTRALDQAELTVTLAGVLERGGKLDARRTLAQARLDALAPQRALARLDVLAEVARRYLAIGMAAQRHAAALDTLAQRQRT
VSAARQRLQAGASPESVLLTAQALQARAELERDRAQQELLAARRQLAVLWGERTPDFGAITGDPLQLPAIPEFEVLAQLL
DATPELARLNGEQRVREARVRLARSQARPDLDWQVGVRRLEGNDATALLGSVWLALGSAARAQPEIRAAEAELALLDIER
QSQASVLYATLADAHGRYRAAQLEVTRMREDVLPALARADAAAERAYRAGATSYLDWAQLQAQRSDARQQQLAAALEAQT
ALIEIQRLTGQPFVREPAAQVTP
>Mature_423_residues
MWLRLTALAVFAVVPCAKAQDLPPKPVLTLDDAIARVARQHPDLRLADGQRAVLSADAERDALRPPLRIGAELENVFGTG
PTRALDQAELTVTLAGVLERGGKLDARRTLAQARLDALAPQRALARLDVLAEVARRYLAIGMAAQRHAAALDTLAQRQRT
VSAARQRLQAGASPESVLLTAQALQARAELERDRAQQELLAARRQLAVLWGERTPDFGAITGDPLQLPAIPEFEVLAQLL
DATPELARLNGEQRVREARVRLARSQARPDLDWQVGVRRLEGNDATALLGSVWLALGSAARAQPEIRAAEAELALLDIER
QSQASVLYATLADAHGRYRAAQLEVTRMREDVLPALARADAAAERAYRAGATSYLDWAQLQAQRSDARQQQLAAALEAQT
ALIEIQRLTGQPFVREPAAQVTP

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 45991; Mature: 45991

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLRLTALAVFAVVPCAKAQDLPPKPVLTLDDAIARVARQHPDLRLADGQRAVLSADAER
CCCHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCEECCCCCHHHCCCCHH
DALRPPLRIGAELENVFGTGPTRALDQAELTVTLAGVLERGGKLDARRTLAQARLDALAP
HHCCCCHHHCHHHHHHHCCCCCCHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCH
QRALARLDVLAEVARRYLAIGMAAQRHAAALDTLAQRQRTVSAARQRLQAGASPESVLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AQALQARAELERDRAQQELLAARRQLAVLWGERTPDFGAITGDPLQLPAIPEFEVLAQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DATPELARLNGEQRVREARVRLARSQARPDLDWQVGVRRLEGNDATALLGSVWLALGSAA
HCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RAQPEIRAAEAELALLDIERQSQASVLYATLADAHGRYRAAQLEVTRMREDVLPALARAD
CCCCCHHHHHHHEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAAERAYRAGATSYLDWAQLQAQRSDARQQQLAAALEAQTALIEIQRLTGQPFVREPAAQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VTP
CCC
>Mature Secondary Structure
MWLRLTALAVFAVVPCAKAQDLPPKPVLTLDDAIARVARQHPDLRLADGQRAVLSADAER
CCCHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCEECCCCCHHHCCCCHH
DALRPPLRIGAELENVFGTGPTRALDQAELTVTLAGVLERGGKLDARRTLAQARLDALAP
HHCCCCHHHCHHHHHHHCCCCCCHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCH
QRALARLDVLAEVARRYLAIGMAAQRHAAALDTLAQRQRTVSAARQRLQAGASPESVLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AQALQARAELERDRAQQELLAARRQLAVLWGERTPDFGAITGDPLQLPAIPEFEVLAQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DATPELARLNGEQRVREARVRLARSQARPDLDWQVGVRRLEGNDATALLGSVWLALGSAA
HCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RAQPEIRAAEAELALLDIERQSQASVLYATLADAHGRYRAAQLEVTRMREDVLPALARAD
CCCCCHHHHHHHEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAAERAYRAGATSYLDWAQLQAQRSDARQQQLAAALEAQTALIEIQRLTGQPFVREPAAQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VTP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]