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The map label for this gene is pcaQ [H]

Identifier: 78049808

GI number: 78049808

Start: 4882279

End: 4883583

Strand: Reverse

Name: pcaQ [H]

Synonym: XCV4252

Alternate gene names: 78049808

Gene position: 4883583-4882279 (Counterclockwise)

Preceding gene: 78049812

Following gene: 78049807

Centisome position: 94.31

GC content: 70.8

Gene sequence:

>1305_bases
ATGCAGCCGATCCCGGAACCAAATCTGCGTCACCTTTACGCGCTGGTCGTGGTGCACCAGGCCGGAAGCATCAGCGCGGC
GGCGCCGCGGGTGAATCTGTCGCAGCCGGCGCTGACCCAGGCGGTGGCGCGATTGGAGCAGCACCTGGGCGTGCGTCTGT
TCGACCGGCACCCAGGTGGCATGTCGGCCACCGAGGCTGCCGGGTTGCTGGTGCCGCGTATCGAGCGGGTGCTGGCGCAT
CTGGCACGGGGGATCGGGGTCGCGCGGCGTGCGCTGCGCCTGCCGGCGCGCCCTGGCCTGGAGCGGCGGGTGTCGCTAGG
CCAGCTGCAGGCCTTGGTGGCGGTGGATGCGGCAGGCAGTTACGCGTTGGCGGCGGTGCGCGCCGGTGTTTCGCAGCCGG
CGATCTATCGCGCGGTGCAAGCGCTGGCCGATGTGATCGAAGTGCCGTTGACGGTACGCCGCGGCAAGACCATGCAGCCC
ACGCCGGTGGCGCTGCGGCTGCTGCGGCAGGTGCGGCTGGCGCTGGCCGAGTTGCGCGCCGGGCTGGACGAGGTGGCCGC
GTTGCGTTCCCAGCACGTCGGGCGCCTCACCCTGGGGGTGATGCCGCTGGCGCGCGCCATCCTGTTGCCGCAGGTGCTGG
CGCGGTTTGCGCGTGCGCATCCGGGGGCCAGCGTCCAGGTGGTCGAGGGCCCGTACGAGCAATTGCTGGCGCGTCTGCGC
GAGGGCGGCCTGGATCTGTTGATCGGTGCGCTGCGCGACCCGTTGCCGGTGCGCGATGTGCTGCAGGAGCCGTTGTTCGA
CGACGAACCGGTGATCGTGGCGCGTAGCGGCCACCCCTTGGCCGGGCAGGGCTACGCGTTTGCGCAACTGCGCGATTACC
CCTGGGTGATCGCTGCCGCCGGCACGCCGGTGCGCGCGCGCTGGGAGCAGCTGTTCGGCGACCACCAGCTGGAGCCGCCG
CCGGTGCGTATCGAATGCGGCGCCGAATTGACCGTGCGTGGCCTGCTGCTGGAAGGCGACTGGTTGACCTTGATGTCGCG
CGACCAGTTCCTGTTCGAGCGCCGCGCCGGCCTGCTCGAGGAAATCGGCAGCGCCGGGCCGCTGCTGCGCCGGCAGATCG
GCATGACCACGCGCAGCGACTGGTATCCCACCCGGATGCAGTCGGCCTTCGTGCAGACGTTGCGGCAGGTCTGCGCCGAA
CGCGTGCAGCCGGCCGATGCGCAGGGCGGGCCGTTTCGTTATTGCCCCCCTGTCTATGCACCGCCGTTGCGTTTGCGCGC
GGCCAAGTCAGAATCGGATTCCTGA

Upstream 100 bases:

>100_bases
CATCCATCCTCGTTAAGAGTGCGCCGAGTCTGGCTGGCCGAAGCCAGCTGGCTCAAGATTCATTTGAGGTATGCATATTG
GTTTTGCTTATAGTTAGAGC

Downstream 100 bases:

>100_bases
TGAAAACGGACCACTGATGCTGCCCGATTGGGTCACAGGTACCTGGCTGCTGGCGCTGGACTGGGCGATCCGCCTGGCCG
CGCTGCTATGGATTCCCGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Pca operon transcriptional activator [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MQPIPEPNLRHLYALVVVHQAGSISAAAPRVNLSQPALTQAVARLEQHLGVRLFDRHPGGMSATEAAGLLVPRIERVLAH
LARGIGVARRALRLPARPGLERRVSLGQLQALVAVDAAGSYALAAVRAGVSQPAIYRAVQALADVIEVPLTVRRGKTMQP
TPVALRLLRQVRLALAELRAGLDEVAALRSQHVGRLTLGVMPLARAILLPQVLARFARAHPGASVQVVEGPYEQLLARLR
EGGLDLLIGALRDPLPVRDVLQEPLFDDEPVIVARSGHPLAGQGYAFAQLRDYPWVIAAAGTPVRARWEQLFGDHQLEPP
PVRIECGAELTVRGLLLEGDWLTLMSRDQFLFERRAGLLEEIGSAGPLLRRQIGMTTRSDWYPTRMQSAFVQTLRQVCAE
RVQPADAQGGPFRYCPPVYAPPLRLRAAKSESDS

Sequences:

>Translated_434_residues
MQPIPEPNLRHLYALVVVHQAGSISAAAPRVNLSQPALTQAVARLEQHLGVRLFDRHPGGMSATEAAGLLVPRIERVLAH
LARGIGVARRALRLPARPGLERRVSLGQLQALVAVDAAGSYALAAVRAGVSQPAIYRAVQALADVIEVPLTVRRGKTMQP
TPVALRLLRQVRLALAELRAGLDEVAALRSQHVGRLTLGVMPLARAILLPQVLARFARAHPGASVQVVEGPYEQLLARLR
EGGLDLLIGALRDPLPVRDVLQEPLFDDEPVIVARSGHPLAGQGYAFAQLRDYPWVIAAAGTPVRARWEQLFGDHQLEPP
PVRIECGAELTVRGLLLEGDWLTLMSRDQFLFERRAGLLEEIGSAGPLLRRQIGMTTRSDWYPTRMQSAFVQTLRQVCAE
RVQPADAQGGPFRYCPPVYAPPLRLRAAKSESDS
>Mature_434_residues
MQPIPEPNLRHLYALVVVHQAGSISAAAPRVNLSQPALTQAVARLEQHLGVRLFDRHPGGMSATEAAGLLVPRIERVLAH
LARGIGVARRALRLPARPGLERRVSLGQLQALVAVDAAGSYALAAVRAGVSQPAIYRAVQALADVIEVPLTVRRGKTMQP
TPVALRLLRQVRLALAELRAGLDEVAALRSQHVGRLTLGVMPLARAILLPQVLARFARAHPGASVQVVEGPYEQLLARLR
EGGLDLLIGALRDPLPVRDVLQEPLFDDEPVIVARSGHPLAGQGYAFAQLRDYPWVIAAAGTPVRARWEQLFGDHQLEPP
PVRIECGAELTVRGLLLEGDWLTLMSRDQFLFERRAGLLEEIGSAGPLLRRQIGMTTRSDWYPTRMQSAFVQTLRQVCAE
RVQPADAQGGPFRYCPPVYAPPLRLRAAKSESDS

Specific function: Activates transcription of the pcaDCHGB operon for the catabolism of the phenolic compound protocatechuate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=243, Percent_Identity=28.3950617283951, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789506, Length=233, Percent_Identity=24.8927038626609, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081904, Length=246, Percent_Identity=27.2357723577236, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788481, Length=319, Percent_Identity=24.1379310344828, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788887, Length=296, Percent_Identity=26.6891891891892, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI157672245, Length=297, Percent_Identity=26.9360269360269, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR012787
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 47292; Mature: 47292

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPIPEPNLRHLYALVVVHQAGSISAAAPRVNLSQPALTQAVARLEQHLGVRLFDRHPGG
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCC
MSATEAAGLLVPRIERVLAHLARGIGVARRALRLPARPGLERRVSLGQLQALVAVDAAGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH
YALAAVRAGVSQPAIYRAVQALADVIEVPLTVRRGKTMQPTPVALRLLRQVRLALAELRA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GLDEVAALRSQHVGRLTLGVMPLARAILLPQVLARFARAHPGASVQVVEGPYEQLLARLR
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
EGGLDLLIGALRDPLPVRDVLQEPLFDDEPVIVARSGHPLAGQGYAFAQLRDYPWVIAAA
HCCHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEEC
GTPVRARWEQLFGDHQLEPPPVRIECGAELTVRGLLLEGDWLTLMSRDQFLFERRAGLLE
CCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEEECCEEEEHHHHHHHHHHHHHHHH
EIGSAGPLLRRQIGMTTRSDWYPTRMQSAFVQTLRQVCAERVQPADAQGGPFRYCPPVYA
HHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PPLRLRAAKSESDS
CCCCEEECCCCCCC
>Mature Secondary Structure
MQPIPEPNLRHLYALVVVHQAGSISAAAPRVNLSQPALTQAVARLEQHLGVRLFDRHPGG
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCC
MSATEAAGLLVPRIERVLAHLARGIGVARRALRLPARPGLERRVSLGQLQALVAVDAAGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH
YALAAVRAGVSQPAIYRAVQALADVIEVPLTVRRGKTMQPTPVALRLLRQVRLALAELRA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GLDEVAALRSQHVGRLTLGVMPLARAILLPQVLARFARAHPGASVQVVEGPYEQLLARLR
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
EGGLDLLIGALRDPLPVRDVLQEPLFDDEPVIVARSGHPLAGQGYAFAQLRDYPWVIAAA
HCCHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEEC
GTPVRARWEQLFGDHQLEPPPVRIECGAELTVRGLLLEGDWLTLMSRDQFLFERRAGLLE
CCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEEECCEEEEHHHHHHHHHHHHHHHH
EIGSAGPLLRRQIGMTTRSDWYPTRMQSAFVQTLRQVCAERVQPADAQGGPFRYCPPVYA
HHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PPLRLRAAKSESDS
CCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]