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The map label for this gene is shlB [H]

Identifier: 78049760

GI number: 78049760

Start: 4823183

End: 4824865

Strand: Reverse

Name: shlB [H]

Synonym: XCV4204

Alternate gene names: 78049760

Gene position: 4824865-4823183 (Counterclockwise)

Preceding gene: 78049761

Following gene: 78049759

Centisome position: 93.17

GC content: 68.75

Gene sequence:

>1683_bases
ATGCGTATGACGTGTCTGGCCGCGGCGGTGTCCGCGTGCCTACTGCTGGCCGCACCTGGGTGGGCGCAGTCGCCGACCGA
TGCCACGGCTGCTGCGCAGTCGGCAGCGGCGGTGCCGGCCATGAGGGACCGGACCGAGGCGGTCACCGTGCAGGTGCGCG
GCTTTCGCGTGCGCGATGTGGGCCACTACCCGGAAGCCGGCATCGACCCGGCCCGCATGCAGGCCGTGGCCGACGCTGCC
TTCGCCGAGCTGGCCCAGGGCCAGCCGGTGGTGGCATTGCGCTTCGATCAATTGCAGGCAGTCGCCGATGCGGTCACCCG
CGCCTACCGGCAGGCCGGCTTCATCGTCAGCACGGCCTATCTGCCGGCGCAGACGCCGGGCCCCGACCAACTGATCGAAA
TCCGCGTGCTGGAAGGGCGCATCGGCCAGATCAGCGTGCAGGGCGCCGCACGCTACCGCGGCAATGCGTTGTCGGCGCCG
CTGCGCCAGCTGCAGGGCCGCCCGCTACGCAAGCAGGACGTGGACACCGCGCTGTTGTATGCGCGCGATCTGCCGGGCGT
GTCGGTGTCGTCGGTGCTGCAGCCAGGCCAGAAGGAAGGCGAGACCGACGTGGTGCTGGTCGCCAGCGAGGCCGCCCGCC
CGTACGTGATCACCCTGGGCGGCAACAACTACGGCACCGAGCTGACCGGCCGTTATCGCGCCCAGGCCGGCATCACCTGG
AATAGCCCGCTTGGCCTGGGCGATGTGTTCGCCGCCAACTACGCCTATTCGCTGGCGCCGCGGCAGAGCCAGATCGGCGC
GCTGTCCTATGGCCTGCCGATCGGCAGCGTGTCCGGCCTAAGCGCGGTGATCGGCGCCAGCCGCAGCGAACTGGAAGTGC
GCAACGGCGTGTTCGCCCGGCTTGGCCTGAAGGGGCCGACCTCCATCGTCTACACCGGCGCCGACTGGAAATTCATCAAC
ACCGAAACGCTGCAGCTGCAGGGCTCGGCGCGCTATCTGCGCGAGCAATCCAAGCTCAGCGCGCTGGGCATGCAGTTGTC
CGACCAGCAGTTCGATGTCGCCGAACTGGGTCTGTCGTTGCGGCGCACCGACCTGCGCTGGCGCGGTGTGGATCTGCTGC
AGGGGAGCGTGCGGCAATCCTTGCGCGACCGCTCGGCGCCGGTGGACCAGATCAGCCCCGGTCGCGACAGCTATTTCACC
ATCGCGCGGCTGGCCTACACGCGCCTGCAATACCTCACCCGCACGCAGCGGCTGTACTTCAAGTTCAACGGCCAATACAG
CGACGACACGCTGACCCCGATGGAGCAGTTCGCTGTCGGTGGGCCCGACAGCGTGCGCGCCTATCCGGTCTCCGATGCAT
TGGGCGACCGCGGGTATTACACCGCGCTCGAATACCACATCGATGCCCCCGGTTTTGCCGATGCCGCATCGCCGTTCAAT
GGCCGGCCCTGGCGCGAGCTGCTGGAGCTGGATGTCTTCGCCGACCACGCCCGCGTGTTCGCCGCCAATGGCCGCCTGGC
GCCGGCCAGTTTCGATGCCGCCGGCGTGGGCCTGACCTTCCGCTTGCCGCAGTACGCCAATTTCGAGTGGCGCATCAGCG
CCGCGCTTCCGACCGGTGCGCGCGACGCCTCCGACGGACGCGACGACGCCCGCATCTACACGCGTTTCGGCTTCACTTTC
TGA

Upstream 100 bases:

>100_bases
GACACGCCGATCGCCGTGCAGTCGCCGCCGTGGCGCCTGCGTGTGCAGCGGGACACGTCGGCCATGCGCAACACCGGATG
GTCTCAGGGGAAATGGACGT

Downstream 100 bases:

>100_bases
GGGATCTGCGCATGCACGCCACCATCCATACCGCGACCTCGCCGCGCACGCTCCCGTTGCGTCACTGCCCGCTGGCCGTT
GCGCTGGCAGCCGCCCTGAT

Product: hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MRMTCLAAAVSACLLLAAPGWAQSPTDATAAAQSAAAVPAMRDRTEAVTVQVRGFRVRDVGHYPEAGIDPARMQAVADAA
FAELAQGQPVVALRFDQLQAVADAVTRAYRQAGFIVSTAYLPAQTPGPDQLIEIRVLEGRIGQISVQGAARYRGNALSAP
LRQLQGRPLRKQDVDTALLYARDLPGVSVSSVLQPGQKEGETDVVLVASEAARPYVITLGGNNYGTELTGRYRAQAGITW
NSPLGLGDVFAANYAYSLAPRQSQIGALSYGLPIGSVSGLSAVIGASRSELEVRNGVFARLGLKGPTSIVYTGADWKFIN
TETLQLQGSARYLREQSKLSALGMQLSDQQFDVAELGLSLRRTDLRWRGVDLLQGSVRQSLRDRSAPVDQISPGRDSYFT
IARLAYTRLQYLTRTQRLYFKFNGQYSDDTLTPMEQFAVGGPDSVRAYPVSDALGDRGYYTALEYHIDAPGFADAASPFN
GRPWRELLELDVFADHARVFAANGRLAPASFDAAGVGLTFRLPQYANFEWRISAALPTGARDASDGRDDARIYTRFGFTF

Sequences:

>Translated_560_residues
MRMTCLAAAVSACLLLAAPGWAQSPTDATAAAQSAAAVPAMRDRTEAVTVQVRGFRVRDVGHYPEAGIDPARMQAVADAA
FAELAQGQPVVALRFDQLQAVADAVTRAYRQAGFIVSTAYLPAQTPGPDQLIEIRVLEGRIGQISVQGAARYRGNALSAP
LRQLQGRPLRKQDVDTALLYARDLPGVSVSSVLQPGQKEGETDVVLVASEAARPYVITLGGNNYGTELTGRYRAQAGITW
NSPLGLGDVFAANYAYSLAPRQSQIGALSYGLPIGSVSGLSAVIGASRSELEVRNGVFARLGLKGPTSIVYTGADWKFIN
TETLQLQGSARYLREQSKLSALGMQLSDQQFDVAELGLSLRRTDLRWRGVDLLQGSVRQSLRDRSAPVDQISPGRDSYFT
IARLAYTRLQYLTRTQRLYFKFNGQYSDDTLTPMEQFAVGGPDSVRAYPVSDALGDRGYYTALEYHIDAPGFADAASPFN
GRPWRELLELDVFADHARVFAANGRLAPASFDAAGVGLTFRLPQYANFEWRISAALPTGARDASDGRDDARIYTRFGFTF
>Mature_560_residues
MRMTCLAAAVSACLLLAAPGWAQSPTDATAAAQSAAAVPAMRDRTEAVTVQVRGFRVRDVGHYPEAGIDPARMQAVADAA
FAELAQGQPVVALRFDQLQAVADAVTRAYRQAGFIVSTAYLPAQTPGPDQLIEIRVLEGRIGQISVQGAARYRGNALSAP
LRQLQGRPLRKQDVDTALLYARDLPGVSVSSVLQPGQKEGETDVVLVASEAARPYVITLGGNNYGTELTGRYRAQAGITW
NSPLGLGDVFAANYAYSLAPRQSQIGALSYGLPIGSVSGLSAVIGASRSELEVRNGVFARLGLKGPTSIVYTGADWKFIN
TETLQLQGSARYLREQSKLSALGMQLSDQQFDVAELGLSLRRTDLRWRGVDLLQGSVRQSLRDRSAPVDQISPGRDSYFT
IARLAYTRLQYLTRTQRLYFKFNGQYSDDTLTPMEQFAVGGPDSVRAYPVSDALGDRGYYTALEYHIDAPGFADAASPFN
GRPWRELLELDVFADHARVFAANGRLAPASFDAAGVGLTFRLPQYANFEWRISAALPTGARDASDGRDDARIYTRFGFTF

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 60614; Mature: 60614

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMTCLAAAVSACLLLAAPGWAQSPTDATAAAQSAAAVPAMRDRTEAVTVQVRGFRVRDV
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEEC
GHYPEAGIDPARMQAVADAAFAELAQGQPVVALRFDQLQAVADAVTRAYRQAGFIVSTAY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEE
LPAQTPGPDQLIEIRVLEGRIGQISVQGAARYRGNALSAPLRQLQGRPLRKQDVDTALLY
CCCCCCCCCCEEEEEEECCCCCEEEECCCHHCCCCCHHHHHHHHCCCCCCHHCCCEEEEE
ARDLPGVSVSSVLQPGQKEGETDVVLVASEAARPYVITLGGNNYGTELTGRYRAQAGITW
ECCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCEEEEEEECCEE
NSPLGLGDVFAANYAYSLAPRQSQIGALSYGLPIGSVSGLSAVIGASRSELEVRNGVFAR
CCCCCCCHHHHHCCEEEECCCCHHCCEEEECCCCCCCCCHHHHHCCCCCHHHHHCCEEEE
LGLKGPTSIVYTGADWKFINTETLQLQGSARYLREQSKLSALGMQLSDQQFDVAELGLSL
ECCCCCCEEEEECCCEEEECCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHH
RRTDLRWRGVDLLQGSVRQSLRDRSAPVDQISPGRDSYFTIARLAYTRLQYLTRTQRLYF
EECCCEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEE
KFNGQYSDDTLTPMEQFAVGGPDSVRAYPVSDALGDRGYYTALEYHIDAPGFADAASPFN
EECCCCCCCCCCCHHHHCCCCCCCCEEEECHHHCCCCCEEEEEEEEECCCCCCCCCCCCC
GRPWRELLELDVFADHARVFAANGRLAPASFDAAGVGLTFRLPQYANFEWRISAALPTGA
CCCHHHHHHHHHHHCCEEEEEECCEECCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCC
RDASDGRDDARIYTRFGFTF
CCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MRMTCLAAAVSACLLLAAPGWAQSPTDATAAAQSAAAVPAMRDRTEAVTVQVRGFRVRDV
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEEC
GHYPEAGIDPARMQAVADAAFAELAQGQPVVALRFDQLQAVADAVTRAYRQAGFIVSTAY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEE
LPAQTPGPDQLIEIRVLEGRIGQISVQGAARYRGNALSAPLRQLQGRPLRKQDVDTALLY
CCCCCCCCCCEEEEEEECCCCCEEEECCCHHCCCCCHHHHHHHHCCCCCCHHCCCEEEEE
ARDLPGVSVSSVLQPGQKEGETDVVLVASEAARPYVITLGGNNYGTELTGRYRAQAGITW
ECCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCEEEEEEECCEE
NSPLGLGDVFAANYAYSLAPRQSQIGALSYGLPIGSVSGLSAVIGASRSELEVRNGVFAR
CCCCCCCHHHHHCCEEEECCCCHHCCEEEECCCCCCCCCHHHHHCCCCCHHHHHCCEEEE
LGLKGPTSIVYTGADWKFINTETLQLQGSARYLREQSKLSALGMQLSDQQFDVAELGLSL
ECCCCCCEEEEECCCEEEECCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHH
RRTDLRWRGVDLLQGSVRQSLRDRSAPVDQISPGRDSYFTIARLAYTRLQYLTRTQRLYF
EECCCEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEE
KFNGQYSDDTLTPMEQFAVGGPDSVRAYPVSDALGDRGYYTALEYHIDAPGFADAASPFN
EECCCCCCCCCCCHHHHCCCCCCCCEEEECHHHCCCCCEEEEEEEEECCCCCCCCCCCCC
GRPWRELLELDVFADHARVFAANGRLAPASFDAAGVGLTFRLPQYANFEWRISAALPTGA
CCCHHHHHHHHHHHCCEEEEEECCEECCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCC
RDASDGRDDARIYTRFGFTF
CCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]