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The map label for this gene is clcB [C]

Identifier: 78049448

GI number: 78049448

Start: 4476726

End: 4478522

Strand: Reverse

Name: clcB [C]

Synonym: XCV3892

Alternate gene names: 78049448

Gene position: 4478522-4476726 (Counterclockwise)

Preceding gene: 78049450

Following gene: 78049447

Centisome position: 86.48

GC content: 66.44

Gene sequence:

>1797_bases
ATGCAGCCACTTTCCCACACCTTGCCGGCCGTGCACGCCATGGCGGCGCAACTCCGCCGGCCGCTGGACGGCTTGCGCAG
GCAGCTGCGCGCCAACGATCTCTGGTTCATCGCCCTGGCCGCGCTGGTGGGGCTGATCGCGGCTGGATTGATGGTGCTGC
AGGCCGGTATCGCGCATGGCCTGCAGAGCTGGCTGTACGCGCTCGCGCCCGAGCAGCGGCTCAGCACGGCCACCTCGATG
ACGGCAACGCAGTTGCTGGTGTTGCCGCTGGGCGGCTTGCTGGTTGGTCTGGTGACGCTGATGGCGCGGCGGCGCAAGCG
GCCCCTCGTGGATGCGGTGGAAGCCAATGCCTTGCATGGCGGGCGCATGTCGATGCGCGACAACCTGATCGTTGCGGTGC
AGACCTTGTTGTCCAACGGCTTCGGTGCGTCGGTGGGACTGGAGGCGACCTACACGCAAATGGGGTCGGGTGCCGGCTCG
CAGCTGGGGCGCGTGTTGCGGGTGCGGCGTGCAGACATGCGCACGCTGGTGGGCGCCGGCGCGGCCGGTGCGATTGCCGG
CGCCTTCGGCGCGCCGCTGGCCGGTGCGTTCTATGCGTTCGAGATCGTCATCGGTGCCTACACGCCATCGGCGTTGGCAC
CGGTGGCCGCCGCCGCATTGGCTGGCGCGTTCATGGCCAATGCCCTGGGCGCAGCGCCGTACTCGTTGCCTGCTGCGGTG
GCCTACCAATTGCAGCCGCGCGACTATGCGGTCTACATCGCGCTGGGCCTGGCGTGCGCGTTGATCGGCATTGCGGTGAT
GCGCCTGGTCGCCGGCATCGAACGCGGCGTGGGCCGCATCAATCTGCCGGTGTGGGGGCGCCCGGTCATCGGTGGGTTGC
TGCTGATTCCGTTGGCGCTGTATTCGCCGCAGGTGCTGTCCTCGGGGCATGGCGCATTGCATCTGGACCTGACCAGCAGC
AGTACCTTGCAGGTGCTCGCCATCCTGTTGGTGCTCAAGTGCATTGCGTCGGGAATTTCGCTGGGTTTCGGCTTCCGCGG
CGGTCTGTTCTTCGCCTCGTTGTTCATGGGCTCGCTGGTGGGCAGCCTGTTCGCGGTGAGCCTGAACCTGTTGCTGGGCG
CTGCAGTGGTGGACACCACCAGTGCATCGCTGGTGGGCATGGCTGCATTGGCGGCGGCCATCGTTGGCGCGCCGATGACC
ATGGCCATGTTGATCCTGGAAGGCACGCACGATTTCGTGCTGGCCAGCGCAGTGATGGCGGCGGTGCTGGTGGCCAATAC
CGTGGTGCGGCAGGTGTTCGGTTATTCGTTCTCCACCTGGCGGCTGCATCTGCGCGGCGAAAACATCCGCAGTGCGCGCG
ATGTGGGCTGGGTGCGCAATCTGTCGGCTGGCAAGATGATGCGCAAGGATGCCAACCACACCGCGCACGACATCAGCGTG
GCCGAATTCCGGCGGCGGTTCCCGTTGGGCTCCACGCAACGCGTGGTGCTGGAAGATGCAGACGGACACTACGCCGGCGT
GGTGCCGCTGGCCGTGCTGTACGCCGACAATGTGCAGCTGGACGCGCCGGTCGGCGACTATGCCAAGCACCGCGATGCGG
CGCTGCTGGCCGACACCGACATCGTGGCGATCATGAAGGTCTTCGATACGACACAGGCCGACGAGTTGGCCGTGATCGAC
AGCGATCGCAAGGTACTGGGCGTGCTGTCGGAGGGATTCGTGCGCAAGCGCTACGCCGAAGAACTGGAAAAGCGCGAGCG
TGAACTGATGGGCGAACGCGTGGCTAGCGACGACTGA

Upstream 100 bases:

>100_bases
ATCGCCGCGCCAGATTGGCTCAGGTCAGCGGCGCTCATGCACACTAGAGCCCACAGCGGACGCCGGCTCTGCCGGTGCCG
ACCCCGCAATCACTGGTCCC

Downstream 100 bases:

>100_bases
GCCGCGCGCTGCCAGCAACGGCTACGCGCATGCGTGCGCATCGTTGATCTGTGTCTGATGTTCGATGCGCAGACACAGGC
GCAGCGTCGGGTTGTTCGGG

Product: voltage gated chloride channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MQPLSHTLPAVHAMAAQLRRPLDGLRRQLRANDLWFIALAALVGLIAAGLMVLQAGIAHGLQSWLYALAPEQRLSTATSM
TATQLLVLPLGGLLVGLVTLMARRRKRPLVDAVEANALHGGRMSMRDNLIVAVQTLLSNGFGASVGLEATYTQMGSGAGS
QLGRVLRVRRADMRTLVGAGAAGAIAGAFGAPLAGAFYAFEIVIGAYTPSALAPVAAAALAGAFMANALGAAPYSLPAAV
AYQLQPRDYAVYIALGLACALIGIAVMRLVAGIERGVGRINLPVWGRPVIGGLLLIPLALYSPQVLSSGHGALHLDLTSS
STLQVLAILLVLKCIASGISLGFGFRGGLFFASLFMGSLVGSLFAVSLNLLLGAAVVDTTSASLVGMAALAAAIVGAPMT
MAMLILEGTHDFVLASAVMAAVLVANTVVRQVFGYSFSTWRLHLRGENIRSARDVGWVRNLSAGKMMRKDANHTAHDISV
AEFRRRFPLGSTQRVVLEDADGHYAGVVPLAVLYADNVQLDAPVGDYAKHRDAALLADTDIVAIMKVFDTTQADELAVID
SDRKVLGVLSEGFVRKRYAEELEKRERELMGERVASDD

Sequences:

>Translated_598_residues
MQPLSHTLPAVHAMAAQLRRPLDGLRRQLRANDLWFIALAALVGLIAAGLMVLQAGIAHGLQSWLYALAPEQRLSTATSM
TATQLLVLPLGGLLVGLVTLMARRRKRPLVDAVEANALHGGRMSMRDNLIVAVQTLLSNGFGASVGLEATYTQMGSGAGS
QLGRVLRVRRADMRTLVGAGAAGAIAGAFGAPLAGAFYAFEIVIGAYTPSALAPVAAAALAGAFMANALGAAPYSLPAAV
AYQLQPRDYAVYIALGLACALIGIAVMRLVAGIERGVGRINLPVWGRPVIGGLLLIPLALYSPQVLSSGHGALHLDLTSS
STLQVLAILLVLKCIASGISLGFGFRGGLFFASLFMGSLVGSLFAVSLNLLLGAAVVDTTSASLVGMAALAAAIVGAPMT
MAMLILEGTHDFVLASAVMAAVLVANTVVRQVFGYSFSTWRLHLRGENIRSARDVGWVRNLSAGKMMRKDANHTAHDISV
AEFRRRFPLGSTQRVVLEDADGHYAGVVPLAVLYADNVQLDAPVGDYAKHRDAALLADTDIVAIMKVFDTTQADELAVID
SDRKVLGVLSEGFVRKRYAEELEKRERELMGERVASDD
>Mature_598_residues
MQPLSHTLPAVHAMAAQLRRPLDGLRRQLRANDLWFIALAALVGLIAAGLMVLQAGIAHGLQSWLYALAPEQRLSTATSM
TATQLLVLPLGGLLVGLVTLMARRRKRPLVDAVEANALHGGRMSMRDNLIVAVQTLLSNGFGASVGLEATYTQMGSGAGS
QLGRVLRVRRADMRTLVGAGAAGAIAGAFGAPLAGAFYAFEIVIGAYTPSALAPVAAAALAGAFMANALGAAPYSLPAAV
AYQLQPRDYAVYIALGLACALIGIAVMRLVAGIERGVGRINLPVWGRPVIGGLLLIPLALYSPQVLSSGHGALHLDLTSS
STLQVLAILLVLKCIASGISLGFGFRGGLFFASLFMGSLVGSLFAVSLNLLLGAAVVDTTSASLVGMAALAAAIVGAPMT
MAMLILEGTHDFVLASAVMAAVLVANTVVRQVFGYSFSTWRLHLRGENIRSARDVGWVRNLSAGKMMRKDANHTAHDISV
AEFRRRFPLGSTQRVVLEDADGHYAGVVPLAVLYADNVQLDAPVGDYAKHRDAALLADTDIVAIMKVFDTTQADELAVID
SDRKVLGVLSEGFVRKRYAEELEKRERELMGERVASDD

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081943, Length=405, Percent_Identity=28.1481481481481, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 62904; Mature: 62904

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]