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The map label for this gene is evgS [H]

Identifier: 78049360

GI number: 78049360

Start: 4389326

End: 4391362

Strand: Reverse

Name: evgS [H]

Synonym: XCV3804

Alternate gene names: 78049360

Gene position: 4391362-4389326 (Counterclockwise)

Preceding gene: 78049361

Following gene: 78049359

Centisome position: 84.8

GC content: 65.19

Gene sequence:

>2037_bases
GTGGTTTCCGATTTGAGCACTCCTTCTTCCAGCCCTACGCTGGCTGCCGCACTGCCGGCCGCCATCGCCGAGCCGTTTCT
GGACCCGGCGATGTATCACGAGATTTTCCACAACATCGATGCCGGGTTTTGCGTCATCGACATGGTATTCGACGGCGAGC
AGGCGGTGGACTATGTGATCCGCACCACCAATGGTGCCTTCGAGCGCTACACCGGCCTGTCGCCCAACGCACTGAACGTC
TCCATCCGCAACCTGCTCCCCGAGCACGAGCAGGAATGGTTCGACCGCTACGGCCACGTCGCGCGCACCGGCAACCGCAT
CCACTTCGAAATGCAGGCCAAGGCGCTCAAGCGCTGGTATTCGGTGGATGCGTTCCGGGTCGGGCAGCCGGAGCAGGCAC
GGGTGGCGATCCTGTTCATGGACATCACCGAGCGCAAACGCGTCGAGCGCGAGCTGGCCGAGAGCGAGGCGCGCTTCAGT
GCGCTGGCCGACGGCTTGCCGATGCCGGTCTGGGTGCTGGACGCGCAAGGCGTGGTGCGCTTCGTCAACAGCGCGTATGG
CGAATTTTTTGGCCTGGATATTTCCAGCGGTACGGTGTCGGCGTGGAGCGAACTGCTGCATCCGGACGACTTGCCGACGT
TCCAGTTCGAGCTGGCCGCATCGCTGCAGGAACAGCGCGGCCTGCGCGCGCTGGTGCGCGCGCGCCGCCATGATGGGCAG
TGGCGCTGGATCGAAATGACCGCAACGCCGCGCTATTCGGCCGACGGCCGCTTCATCGGGCTGGCCGGCAGCAGCCCGGA
CGTGACCGAGCAGCGCGAGATCGAACTGGCGCGCGAGCAATTGCTGGAATCCGAGCGCAGCGCGCGCAACGAGGCCGAAA
GCATGGCGCGGTTGAAGGACGAGTTCCTGGCCACGCTGTCGCACGAATTGCGTACCCCGCTGACCACCATCCTGGGCTGG
AGCGAGTTGCTGCTGCAGCGGGTCGAAGAAGGCCAGCCGTATTACAAGGGGCTGTCGGTGATCGCCAGCAGCGCACGTGC
GCAGAAGCGGCTGATTTCCGACATGCTCGATCTCAGCAGCATGTTGCTGGGCAAGGTGCAGCTGGAAGTCGAATCGCTGG
ATCTGGTCGAGCAGGTGCGCGAAGCCTTGAACACCCAGGAACTGGCTGCCGAAGGCAAGGACCAGGTCCTGGAGCTGCAC
GTGCCGCCCACGCCCTGCCTGGTGCTTGGCGATGCCACGCGCCTTCAGCAGGTGTTGTGGAACCTGCTGTCCAACGCAAT
CAAGTTCACCCCGGCACATGGTCGTATCGACGTCAAAATCGAGCGCGACGATGGGCATCTGGTGGTCTCGGTCTGCGATT
CCGGCGATGGCATTGCAGCCGAATTCCTGCCGCACCTGTTCGGTCGTTTCCGCCAGGCCGACGGCACCACCACGCGCCAG
CATGGCGGGCTGGGTCTGGGCCTGGCGATCGTGCAGCAGCTGGTGGAAATGCACGGCGGACAGGTCGGCGCCACCAGTGG
CGGCCGTGGCAAGGGCGCGACCTTCACCGTGCGGCTGCCGGAACATATTCCCGACCAGGCCAAGCGCCCACGCCGCGAGC
TGCGGCGGCGTCTGATGTCCGAACAGATCGTCGAAGCGCGCGCGCTCAATGGCTTGCGCCTGCTGGCGGTCGAAGATCAA
CCGGACATGCTCGATTATCTGCGGCGTCTGCTCGAAGAGCAGGGCGCCGAAGTGGTGGTCGCCGGCAGCGCCACCGATGC
GCTGGCATTGATCGATCATCGTGGCCACGCTCGCTTCGATCTGATGCTGACCGATATCGGCATGCCGGGCATGGACGGTT
ACGGCTTGATCCGTACCGTGCGCGAAAACCTCGGGCTGGATGCCACCGCGTTGCCGGCCGTGGCAGTCACCGCGCTGGCC
CGCGAAGACGACCGCAAGCGCGCGCTGGAGTCCGGGTTTCAGGAACATCTGGCCAAGCCCTACAGCGTGGCGCAACTGGT
CACGGCCGTGCGTGCCGCGCGCCAGGCGGTGGAGTAA

Upstream 100 bases:

>100_bases
TGGCTGGGCGAGGAAAGCGTGAACTTGCCCAGCCCCACGTGCACCCGCTGACGACATCAGGCATGGTTTCATCTGCCCGT
CATCCGCTCCGGCAGCATCC

Downstream 100 bases:

>100_bases
CCGGCGCGCAGCGCACAGCCGCGCAGCGGGTCACCGCAAGGTGGTGAGGCGACGCGTTGGATGCGCAGTAGCGTGTGTGT
GGCTTGCGTACCTGGCGTCT

Product: two-component system sensor histidine kinase-response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MVSDLSTPSSSPTLAAALPAAIAEPFLDPAMYHEIFHNIDAGFCVIDMVFDGEQAVDYVIRTTNGAFERYTGLSPNALNV
SIRNLLPEHEQEWFDRYGHVARTGNRIHFEMQAKALKRWYSVDAFRVGQPEQARVAILFMDITERKRVERELAESEARFS
ALADGLPMPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLHPDDLPTFQFELAASLQEQRGLRALVRARRHDGQ
WRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERSARNEAESMARLKDEFLATLSHELRTPLTTILGW
SELLLQRVEEGQPYYKGLSVIASSARAQKRLISDMLDLSSMLLGKVQLEVESLDLVEQVREALNTQELAAEGKDQVLELH
VPPTPCLVLGDATRLQQVLWNLLSNAIKFTPAHGRIDVKIERDDGHLVVSVCDSGDGIAAEFLPHLFGRFRQADGTTTRQ
HGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHIPDQAKRPRRELRRRLMSEQIVEARALNGLRLLAVEDQ
PDMLDYLRRLLEEQGAEVVVAGSATDALALIDHRGHARFDLMLTDIGMPGMDGYGLIRTVRENLGLDATALPAVAVTALA
REDDRKRALESGFQEHLAKPYSVAQLVTAVRAARQAVE

Sequences:

>Translated_678_residues
MVSDLSTPSSSPTLAAALPAAIAEPFLDPAMYHEIFHNIDAGFCVIDMVFDGEQAVDYVIRTTNGAFERYTGLSPNALNV
SIRNLLPEHEQEWFDRYGHVARTGNRIHFEMQAKALKRWYSVDAFRVGQPEQARVAILFMDITERKRVERELAESEARFS
ALADGLPMPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLHPDDLPTFQFELAASLQEQRGLRALVRARRHDGQ
WRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERSARNEAESMARLKDEFLATLSHELRTPLTTILGW
SELLLQRVEEGQPYYKGLSVIASSARAQKRLISDMLDLSSMLLGKVQLEVESLDLVEQVREALNTQELAAEGKDQVLELH
VPPTPCLVLGDATRLQQVLWNLLSNAIKFTPAHGRIDVKIERDDGHLVVSVCDSGDGIAAEFLPHLFGRFRQADGTTTRQ
HGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHIPDQAKRPRRELRRRLMSEQIVEARALNGLRLLAVEDQ
PDMLDYLRRLLEEQGAEVVVAGSATDALALIDHRGHARFDLMLTDIGMPGMDGYGLIRTVRENLGLDATALPAVAVTALA
REDDRKRALESGFQEHLAKPYSVAQLVTAVRAARQAVE
>Mature_678_residues
MVSDLSTPSSSPTLAAALPAAIAEPFLDPAMYHEIFHNIDAGFCVIDMVFDGEQAVDYVIRTTNGAFERYTGLSPNALNV
SIRNLLPEHEQEWFDRYGHVARTGNRIHFEMQAKALKRWYSVDAFRVGQPEQARVAILFMDITERKRVERELAESEARFS
ALADGLPMPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLHPDDLPTFQFELAASLQEQRGLRALVRARRHDGQ
WRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERSARNEAESMARLKDEFLATLSHELRTPLTTILGW
SELLLQRVEEGQPYYKGLSVIASSARAQKRLISDMLDLSSMLLGKVQLEVESLDLVEQVREALNTQELAAEGKDQVLELH
VPPTPCLVLGDATRLQQVLWNLLSNAIKFTPAHGRIDVKIERDDGHLVVSVCDSGDGIAAEFLPHLFGRFRQADGTTTRQ
HGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHIPDQAKRPRRELRRRLMSEQIVEARALNGLRLLAVEDQ
PDMLDYLRRLLEEQGAEVVVAGSATDALALIDHRGHARFDLMLTDIGMPGMDGYGLIRTVRENLGLDATALPAVAVTALA
REDDRKRALESGFQEHLAKPYSVAQLVTAVRAARQAVE

Specific function: Member of the two-component regulatory system evgS/evgA. Phosphorylates evgA via a four-step phosphorelay in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=560, Percent_Identity=29.1071428571429, Blast_Score=176, Evalue=6e-45,
Organism=Escherichia coli, GI48994928, Length=556, Percent_Identity=30.0359712230216, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI87081816, Length=350, Percent_Identity=32.5714285714286, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=38.9830508474576, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=36.6935483870968, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=34.2741935483871, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786783, Length=247, Percent_Identity=33.6032388663968, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=31.8548387096774, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1786600, Length=384, Percent_Identity=27.8645833333333, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=29.4117647058824, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=31.140350877193, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788279, Length=222, Percent_Identity=28.3783783783784, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1788549, Length=286, Percent_Identity=30.0699300699301, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=236, Percent_Identity=32.6271186440678, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87082128, Length=268, Percent_Identity=27.6119402985075, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790551, Length=225, Percent_Identity=29.7777777777778, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87082012, Length=121, Percent_Identity=32.2314049586777, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=149, Percent_Identity=30.8724832214765, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75185; Mature: 75185

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSDLSTPSSSPTLAAALPAAIAEPFLDPAMYHEIFHNIDAGFCVIDMVFDGEQAVDYVI
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHH
RTTNGAFERYTGLSPNALNVSIRNLLPEHEQEWFDRYGHVARTGNRIHFEMQAKALKRWY
CCCCCCHHHHCCCCCCCEEEEHHHHCCHHHHHHHHHHCCHHCCCCEEEEEHHHHHHHHHH
SVDAFRVGQPEQARVAILFMDITERKRVERELAESEARFSALADGLPMPVWVLDAQGVVR
CCCCEECCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHH
FVNSAYGEFFGLDISSGTVSAWSELLHPDDLPTFQFELAASLQEQRGLRALVRARRHDGQ
HHHHHHHHHEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
WRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERSARNEAESMARLKD
EEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFLATLSHELRTPLTTILGWSELLLQRVEEGQPYYKGLSVIASSARAQKRLISDMLDLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLGKVQLEVESLDLVEQVREALNTQELAAEGKDQVLELHVPPTPCLVLGDATRLQQVLW
HHHHHHHEEHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCEEEECCHHHHHHHHH
NLLSNAIKFTPAHGRIDVKIERDDGHLVVSVCDSGDGIAAEFLPHLFGRFRQADGTTTRQ
HHHHHHEEECCCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCC
HGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHIPDQAKRPRRELRRRLMS
CCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
EQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVVAGSATDALALIDHRGHARFD
HHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHEEECCCCCEEE
LMLTDIGMPGMDGYGLIRTVRENLGLDATALPAVAVTALAREDDRKRALESGFQEHLAKP
EEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCH
YSVAQLVTAVRAARQAVE
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSDLSTPSSSPTLAAALPAAIAEPFLDPAMYHEIFHNIDAGFCVIDMVFDGEQAVDYVI
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHH
RTTNGAFERYTGLSPNALNVSIRNLLPEHEQEWFDRYGHVARTGNRIHFEMQAKALKRWY
CCCCCCHHHHCCCCCCCEEEEHHHHCCHHHHHHHHHHCCHHCCCCEEEEEHHHHHHHHHH
SVDAFRVGQPEQARVAILFMDITERKRVERELAESEARFSALADGLPMPVWVLDAQGVVR
CCCCEECCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHH
FVNSAYGEFFGLDISSGTVSAWSELLHPDDLPTFQFELAASLQEQRGLRALVRARRHDGQ
HHHHHHHHHEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
WRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERSARNEAESMARLKD
EEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFLATLSHELRTPLTTILGWSELLLQRVEEGQPYYKGLSVIASSARAQKRLISDMLDLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLGKVQLEVESLDLVEQVREALNTQELAAEGKDQVLELHVPPTPCLVLGDATRLQQVLW
HHHHHHHEEHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCEEEECCHHHHHHHHH
NLLSNAIKFTPAHGRIDVKIERDDGHLVVSVCDSGDGIAAEFLPHLFGRFRQADGTTTRQ
HHHHHHEEECCCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCC
HGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHIPDQAKRPRRELRRRLMS
CCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
EQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVVAGSATDALALIDHRGHARFD
HHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHEEECCCCCEEE
LMLTDIGMPGMDGYGLIRTVRENLGLDATALPAVAVTALAREDDRKRALESGFQEHLAKP
EEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCH
YSVAQLVTAVRAARQAVE
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]