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The map label for this gene is metI [H]

Identifier: 78049344

GI number: 78049344

Start: 4374670

End: 4375365

Strand: Reverse

Name: metI [H]

Synonym: XCV3788

Alternate gene names: 78049344

Gene position: 4375365-4374670 (Counterclockwise)

Preceding gene: 78049345

Following gene: 78049343

Centisome position: 84.49

GC content: 67.96

Gene sequence:

>696_bases
ATGACCCCGATCGTTGCTGCCGCCGGCGGTTTCTTCCGCAATCTCGATGCCGCCAAGTGGAGCGACATCGGCCAGGCCAC
CCTCGATACCTTGCTGATGCTGGCCGGTGCGTTGCCGCTGACATTGCTGATCGGCCTGCCGCTGGGCGTTGCGCTGTTCC
TGTGCGGCGCGCCGCAGTTGCGCCGGCGCCCGGTGCTGTACGGCGCGCTCGCGGCGCTGATCAACCTGCTGCGCTCGGTG
CCCTTCATCATTTTGATGATCGCGATGATCCCGCTCACGCTGATGCTGATGGGCACTTCGCTGGGCGTGCGCGGCGCGAT
CCTGCCGCTGGTGGTCGGCGCCGCGCCGTTTTACGCACGCCTGGTGGAAACCGCGCTGCGCGAAGTCGACCGCGGGATCA
TCGAAGCCAGCCAGGCAATGGGCGCCACTACCCGGCAACTGGTGCTGCGGGTGCTGTTGCCCGAAGCGCGCCCCGGCCTG
ATCGCCGGCGCCACAGTGACCACCATCGCGCTGATCGGCTTCACCGCGATGGGCGGTGCGATCGGTTCCGGCGGCCTGGG
CGATGTGGCCTATCGCGAGGGCTACCTGCGCTCGCACTCGGACGTGGCACTGATCACCGTCATCGCCTTGCTGGTACTGG
TGCAGGTGCTGCAGATGCTGGGCGACCGCCTGGTGGCGCATTACAGCCGGCGCTGA

Upstream 100 bases:

>100_bases
CGCCCTACGGCCAGCTCATCGTCGCCCTGACCGGCGGCGACCAGAACGCTGCACGCGCCGGTTTCGTCGCCGCCGGCGTG
CAGGTGGAGGATCTGCGCGT

Downstream 100 bases:

>100_bases
GCCGGTGCGCGGCCGTTGGGGCGCACGTGACCCAACAGCTGCATCGCCGCCCCGTCCGCACCGCGCGGTGCATCGCTGCC
ACACGCCGTGTCTGGTAGGT

Product: D-methionine ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTPIVAAAGGFFRNLDAAKWSDIGQATLDTLLMLAGALPLTLLIGLPLGVALFLCGAPQLRRRPVLYGALAALINLLRSV
PFIILMIAMIPLTLMLMGTSLGVRGAILPLVVGAAPFYARLVETALREVDRGIIEASQAMGATTRQLVLRVLLPEARPGL
IAGATVTTIALIGFTAMGGAIGSGGLGDVAYREGYLRSHSDVALITVIALLVLVQVLQMLGDRLVAHYSRR

Sequences:

>Translated_231_residues
MTPIVAAAGGFFRNLDAAKWSDIGQATLDTLLMLAGALPLTLLIGLPLGVALFLCGAPQLRRRPVLYGALAALINLLRSV
PFIILMIAMIPLTLMLMGTSLGVRGAILPLVVGAAPFYARLVETALREVDRGIIEASQAMGATTRQLVLRVLLPEARPGL
IAGATVTTIALIGFTAMGGAIGSGGLGDVAYREGYLRSHSDVALITVIALLVLVQVLQMLGDRLVAHYSRR
>Mature_230_residues
TPIVAAAGGFFRNLDAAKWSDIGQATLDTLLMLAGALPLTLLIGLPLGVALFLCGAPQLRRRPVLYGALAALINLLRSVP
FIILMIAMIPLTLMLMGTSLGVRGAILPLVVGAAPFYARLVETALREVDRGIIEASQAMGATTRQLVLRVLLPEARPGLI
AGATVTTIALIGFTAMGGAIGSGGLGDVAYREGYLRSHSDVALITVIALLVLVQVLQMLGDRLVAHYSRR

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=190, Percent_Identity=49.4736842105263, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1788451, Length=208, Percent_Identity=31.7307692307692, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24248; Mature: 24116

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPIVAAAGGFFRNLDAAKWSDIGQATLDTLLMLAGALPLTLLIGLPLGVALFLCGAPQL
CCCCHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RRRPVLYGALAALINLLRSVPFIILMIAMIPLTLMLMGTSLGVRGAILPLVVGAAPFYAR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVETALREVDRGIIEASQAMGATTRQLVLRVLLPEARPGLIAGATVTTIALIGFTAMGGA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCC
IGSGGLGDVAYREGYLRSHSDVALITVIALLVLVQVLQMLGDRLVAHYSRR
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPIVAAAGGFFRNLDAAKWSDIGQATLDTLLMLAGALPLTLLIGLPLGVALFLCGAPQL
CCCHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RRRPVLYGALAALINLLRSVPFIILMIAMIPLTLMLMGTSLGVRGAILPLVVGAAPFYAR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVETALREVDRGIIEASQAMGATTRQLVLRVLLPEARPGLIAGATVTTIALIGFTAMGGA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCC
IGSGGLGDVAYREGYLRSHSDVALITVIALLVLVQVLQMLGDRLVAHYSRR
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]