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The map label for this gene is tctE [H]

Identifier: 78049166

GI number: 78049166

Start: 4150851

End: 4152236

Strand: Reverse

Name: tctE [H]

Synonym: XCV3610

Alternate gene names: 78049166

Gene position: 4152236-4150851 (Counterclockwise)

Preceding gene: 78049167

Following gene: 78049165

Centisome position: 80.18

GC content: 68.9

Gene sequence:

>1386_bases
ATGGCTGAGCCGCTGGTGGTGGCACCGTCGATCCGGCGCACCTTGCTGCTGTACCTGGGCAGCCTGTCGCTGCTGGGTGC
GGTGGTGCTGTTCTTTGCCGCACGCGATTACGGCGAGCGGGCGGCCAATCGGTCCTACGATCACCTGCTGGTGTCCTCGG
CGCTGTCGATCATCGACAGCGTGGCGTTGGTCGGCGGTGACTGGCAGGTGGATCTGCCGTATGCCTCGCTGGATCTGCTC
GGCATGGCGCCGGAAGACCGCGTGTTCTATCGCGTGTTCGATGCGCAGGGCCGCACCATCACCGGCGAAGACACGCTGCC
GCCGCCGCCGCGTGCGCCCCGCGACGAGCGGCCGCTGCTGTTCGATGCGCAGTACAGCGGCGAGCCGGTGCGCTTTGCGG
TGGTGATGCATCGGGTGGCGTCGGCCTCGGGGCAGGGCGAGGTGCGCGTGCAGGTGGGCCAGACCCGGCGCGCACGCGAT
GCGGTGGCGCGCGATGTGGTGCTCAACGCCTTGGTGGCGATCGGCGTGCTGTCGCTGCTGGCGCTGGGCCTGGTGTGGCT
GGGGGTCTACCGCGCGTTGCGGCCGCTGCAGCGCATCGAGCGCGATCTGTCGCGGCGCGAACCCTCCGACCTCAAGCCGC
TGAACGTGCCGGCGCCGCAGGAAATGCAGTTGATGGTGACCGCGCTCAACCGGTTCATGGCGCGGCTATCGTCCAGCAAC
GAAACCCTGCGCGCCTTCATGGCCGAAGCCGCGCACCAGATGCGCACACCACTGGCGGCCTTGCGCGCGCAGGCGCAGCT
GGCGATGGACGACGACGACCCGCACGAGATGCAACGCAGCCTGGTGGCGATCGAGCGCAACGCCAGCCATATGAGCCGGC
TGCTCAATCAGTTGCTCAGCGATGCCAGCGTGATCCACCGCGCCAACCTGCAGCGCTTTGCCACCGTGGATCTGGCCGAT
GTACTGCATCAGGCCCTGCACGAAGCGCTGCCGCGCAGCCCAGGCGCACCGCGCGTGCAGCTGGCGATCGACCCGAAACC
GGCGCTGCTGCGCGGCGATGCCTTGCTGCTCCGCGAGGCGCTGAAAAACCTGATCGACAACGCCTGCAAATACGGTGCCG
GTGCCCCGCTGCAGGTGGCGCTCACCAGCGACGGCAACCACCACGTGCTGACCATTGCCGATCATGGCCCGGGCATTCCG
GCGGCCGAAGCCGAGCGTGTGTTCGAGCGTTTCGTGCGGGGGGCGGATGCCCCGGCCGGCGGCGCCGGGCTGGGGTTGGC
CATCGTCAAGCGCGTGGTGGAAGCGCATGGCGGGCGCATCGATCTGTCCAACCGCATCGGTGGCGGCTTGATCGCCTCGC
TGCATTTTCCCGGAGGAGACGCGTGA

Upstream 100 bases:

>100_bases
CGCAAGCTGGCCGCCGCGCCGTTGCGTATCGTCACCGTGCGCGGTGCCGGTTACAAACTCGAAGAAGCCGACCCGCATGC
GCCGGTGGAGCCGGGCGCCG

Downstream 100 bases:

>100_bases
TGCGGGCGATGTGGATGCTGCTGTTGCTGCTGGTCCATGGCCTCGCCTGCGCGGCGCCCGGCGATGTGCGGCGCTTTCCT
GCACAGGGCCCGGTGCGTGT

Product: two-component system sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MAEPLVVAPSIRRTLLLYLGSLSLLGAVVLFFAARDYGERAANRSYDHLLVSSALSIIDSVALVGGDWQVDLPYASLDLL
GMAPEDRVFYRVFDAQGRTITGEDTLPPPPRAPRDERPLLFDAQYSGEPVRFAVVMHRVASASGQGEVRVQVGQTRRARD
AVARDVVLNALVAIGVLSLLALGLVWLGVYRALRPLQRIERDLSRREPSDLKPLNVPAPQEMQLMVTALNRFMARLSSSN
ETLRAFMAEAAHQMRTPLAALRAQAQLAMDDDDPHEMQRSLVAIERNASHMSRLLNQLLSDASVIHRANLQRFATVDLAD
VLHQALHEALPRSPGAPRVQLAIDPKPALLRGDALLLREALKNLIDNACKYGAGAPLQVALTSDGNHHVLTIADHGPGIP
AAEAERVFERFVRGADAPAGGAGLGLAIVKRVVEAHGGRIDLSNRIGGGLIASLHFPGGDA

Sequences:

>Translated_461_residues
MAEPLVVAPSIRRTLLLYLGSLSLLGAVVLFFAARDYGERAANRSYDHLLVSSALSIIDSVALVGGDWQVDLPYASLDLL
GMAPEDRVFYRVFDAQGRTITGEDTLPPPPRAPRDERPLLFDAQYSGEPVRFAVVMHRVASASGQGEVRVQVGQTRRARD
AVARDVVLNALVAIGVLSLLALGLVWLGVYRALRPLQRIERDLSRREPSDLKPLNVPAPQEMQLMVTALNRFMARLSSSN
ETLRAFMAEAAHQMRTPLAALRAQAQLAMDDDDPHEMQRSLVAIERNASHMSRLLNQLLSDASVIHRANLQRFATVDLAD
VLHQALHEALPRSPGAPRVQLAIDPKPALLRGDALLLREALKNLIDNACKYGAGAPLQVALTSDGNHHVLTIADHGPGIP
AAEAERVFERFVRGADAPAGGAGLGLAIVKRVVEAHGGRIDLSNRIGGGLIASLHFPGGDA
>Mature_460_residues
AEPLVVAPSIRRTLLLYLGSLSLLGAVVLFFAARDYGERAANRSYDHLLVSSALSIIDSVALVGGDWQVDLPYASLDLLG
MAPEDRVFYRVFDAQGRTITGEDTLPPPPRAPRDERPLLFDAQYSGEPVRFAVVMHRVASASGQGEVRVQVGQTRRARDA
VARDVVLNALVAIGVLSLLALGLVWLGVYRALRPLQRIERDLSRREPSDLKPLNVPAPQEMQLMVTALNRFMARLSSSNE
TLRAFMAEAAHQMRTPLAALRAQAQLAMDDDDPHEMQRSLVAIERNASHMSRLLNQLLSDASVIHRANLQRFATVDLADV
LHQALHEALPRSPGAPRVQLAIDPKPALLRGDALLLREALKNLIDNACKYGAGAPLQVALTSDGNHHVLTIADHGPGIPA
AEAERVFERFVRGADAPAGGAGLGLAIVKRVVEAHGGRIDLSNRIGGGLIASLHFPGGDA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=389, Percent_Identity=30.8483290488432, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1790551, Length=298, Percent_Identity=32.8859060402685, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786912, Length=293, Percent_Identity=31.740614334471, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786783, Length=292, Percent_Identity=27.0547945205479, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787374, Length=293, Percent_Identity=25.938566552901, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=26.7558528428094, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788393, Length=271, Percent_Identity=26.9372693726937, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789808, Length=282, Percent_Identity=26.241134751773, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788279, Length=279, Percent_Identity=28.3154121863799, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=29.3877551020408, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=29.3617021276596, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=30.6666666666667, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081816, Length=336, Percent_Identity=27.0833333333333, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=224, Percent_Identity=26.7857142857143, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=25.9259259259259, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87082128, Length=297, Percent_Identity=25.5892255892256, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789149, Length=249, Percent_Identity=24.8995983935743, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=26.5765765765766, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=25.3456221198157, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788713, Length=222, Percent_Identity=23.8738738738739, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49804; Mature: 49673

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPLVVAPSIRRTLLLYLGSLSLLGAVVLFFAARDYGERAANRSYDHLLVSSALSIIDS
CCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VALVGGDWQVDLPYASLDLLGMAPEDRVFYRVFDAQGRTITGEDTLPPPPRAPRDERPLL
HHHCCCCEEEECCCHHHHHCCCCCCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCEE
FDAQYSGEPVRFAVVMHRVASASGQGEVRVQVGQTRRARDAVARDVVLNALVAIGVLSLL
EECCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLVWLGVYRALRPLQRIERDLSRREPSDLKPLNVPAPQEMQLMVTALNRFMARLSSSN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCH
ETLRAFMAEAAHQMRTPLAALRAQAQLAMDDDDPHEMQRSLVAIERNASHMSRLLNQLLS
HHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
DASVIHRANLQRFATVDLADVLHQALHEALPRSPGAPRVQLAIDPKPALLRGDALLLREA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHCCHHHHHHHH
LKNLIDNACKYGAGAPLQVALTSDGNHHVLTIADHGPGIPAAEAERVFERFVRGADAPAG
HHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
GAGLGLAIVKRVVEAHGGRIDLSNRIGGGLIASLHFPGGDA
CCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
AEPLVVAPSIRRTLLLYLGSLSLLGAVVLFFAARDYGERAANRSYDHLLVSSALSIIDS
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VALVGGDWQVDLPYASLDLLGMAPEDRVFYRVFDAQGRTITGEDTLPPPPRAPRDERPLL
HHHCCCCEEEECCCHHHHHCCCCCCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCEE
FDAQYSGEPVRFAVVMHRVASASGQGEVRVQVGQTRRARDAVARDVVLNALVAIGVLSLL
EECCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLVWLGVYRALRPLQRIERDLSRREPSDLKPLNVPAPQEMQLMVTALNRFMARLSSSN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCH
ETLRAFMAEAAHQMRTPLAALRAQAQLAMDDDDPHEMQRSLVAIERNASHMSRLLNQLLS
HHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
DASVIHRANLQRFATVDLADVLHQALHEALPRSPGAPRVQLAIDPKPALLRGDALLLREA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHCCHHHHHHHH
LKNLIDNACKYGAGAPLQVALTSDGNHHVLTIADHGPGIPAAEAERVFERFVRGADAPAG
HHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
GAGLGLAIVKRVVEAHGGRIDLSNRIGGGLIASLHFPGGDA
CCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]