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The map label for this gene is recG [H]

Identifier: 78049064

GI number: 78049064

Start: 4019756

End: 4021909

Strand: Reverse

Name: recG [H]

Synonym: XCV3508

Alternate gene names: 78049064

Gene position: 4021909-4019756 (Counterclockwise)

Preceding gene: 78049065

Following gene: 78049063

Centisome position: 77.67

GC content: 67.73

Gene sequence:

>2154_bases
GTGTCGCGCACGCGCGTCGTCACACCGAGTCTGGCCGTCGCCGGCCAGGCTCGGCTGTCCAGCCTGCCCGGTGTCGGCCC
GAAAGTGGCCGACAAGTTCGCTGCGCGCGGCATCCTGAGCGTGCAGGACCTGTGGCTGCATCTGCCGCTGCGTTACGAAG
ACCGCACGCGCTTGACCACCATCGCGCAGCTGCAAGGTGGCGTGCCGGCGCAGGTCGAAGGACGCGTGGAGGCTGTGGAG
CGCGGCTTCCGCTTCCGGCCGGTGCTGCGCGTGGCAGTGTCCGACGCCTCGCACGGGACGCTGGTGCTGCGCTTCTTTCA
TTTTCGTGCGGCGCAGGTCGCGCAGTTCGCCGTCGGTACGCGGCTGCGGGTGTTCGGCACACCCAAGCCCGGCCAGCACG
GCTGGGAGATCGTGCACCCCAGTTACCGCGTGCTCGCACCGGACGAAGATGCCGGGTTGGGCGACAGTCTGGATCCGGTG
TATCCGGTGCTCGAAGGCGTTGGCCCGGCGACGTTGCGCAAGCTCATCGGCCAGGCGCTGGAGCGTCTGCCGCCCGAAAG
TGCGCTGGAATTGTTGCCACCGCACTGGCTGCAGGACGAGCGATTGCCCTCATTGCGCGCGGCTTTGCTCACCATGCATC
GCCCGCCGGTTGGCACTGATCCACAGCAACTGCTCGCCGGAGGCCACCCGGCCCAGCAGCGCCTGGCAATCGAGGAATTG
CTGGCGCACCAGCTCAGCCTGCGCCGGCAACGCATCGCGTTGCAGCGTCTGCACGCGCCCAGCCTGCCCGGCAACGGCAC
GTTGGTGCAGCAATTGTGCAAGGCGCTGCCGTTCCAGCTGACCGGCGCGCAACAACGCGTGTTCGAACAGATTGCGCATG
ACCTTGCGCACCCCTCGCCGATGCTGCGGCTGGTACAGGGCGATGTCGGCAGCGGCAAGACCGTGGTCGCGGCGCTGGCG
GCCATGTTGGCGGTGGAGCAGGGCAAGCAGGTCGCACTTGCCGCGCCCACCGAATTGCTGGCCGAGCAGCACCTCACCAA
TCTGCGCGGCTGGTTGGAACCGTTGGGCATCCGCATCGTCTGGCTGGCAGGCAAGGTCACCGGCAAGGCGCGCGCTGCAG
TGATGGCCGAGGTCGCCTCCGGTCAGGCGCAGGTCGTGGTCGGCACGCATGCGTTGATGCAGGAGGCGGTGGTCTTCCAC
GACCTGGCGTTGGCCATCATCGACGAGCAACACCGCTTCGGCGTGCATCAGCGCCTTGCGTTGCGCGACAAGGGAGCGGC
GGCGGGCAGCGTGCCGCATCAGCTGGTGATGACCGCCACGCCCATTCCGCGCACGTTGGCGATGTCGGCTTACGCAGATC
TGGATGTTTCGGCCATCGACGAATTGCCGCCCGGCCGCACGCCGGTGCAGACGATCGTGCTGAGCGCGGAGCGCCGGCCC
GAATTGGTCGAACGCATTCGCGCCGCCTGCGCCGAAGGACGGCAGGCATATTGGGTGTGCACCCTGATCGAAGAAAGCGA
AGAACCCGAGAAAGGCGCGCAAGGCCAGCAAGGCGGTCCGCCGCGCATCGAAGCGCAGGCCGCCGAAGTCACCTTCGAGG
CCTTGTCGGCGCAGTTGCCGGGCGTGCGGGTGGCGCTGGTGCACGGCCGCATGAAGCCGGCCGAAAAGCAGAAGGCCATG
CTGGATTTCAAGCAGGGCCGCAGCGACCTGTTGGTGGCCACCACCGTGATCGAAGTCGGCGTGGACGTGCCTAACGCCTC
GTTGATGATCATCGAAAATGCCGAGCGGCTGGGCCTGGCCCAATTGCATCAGTTGCGCGGTCGGGTCGGGCGTGGCGCAG
CCGCCTCAAGTTGCGTGCTGCTGTACCAGGCGCCGTTGTCGATGATGGCGCGGCAGCGTCTGGAAACCATGCGCCAGACC
AACGACGGTTTCGTGATCGCGGAGAAGGATCTGGAGTTGCGTGGCCCGGGCGAATTGCTTGGCACCCGGCAAACCGGCCT
GGCCAGTTTCCGCATCGCCGATCTGGCACGCGACGCCGGGCTGTTGCCGCGCGTGCAGGTACTGGCCGAGCGGCTGCTGG
ACGAGGCGCCGGAAATCGCCGACCGCGTGGTCGAACGCTGGATCGGCGGCGCGGTGCGGTATGCGGCCGCTTGA

Upstream 100 bases:

>100_bases
CGGCGCGTTCGACCATCGAAGTCTCCGGTCTGCCCAAGGGCGCCGGCTTCGAAGTCGATGCAGTGATGGTGATCGAGTGA
TCCTGCGCCGCTGATCGGCC

Downstream 100 bases:

>100_bases
GCGGCCGGGAGTCGGGAATCGGGATTCGTAACAGCGTGGCGGCTGCGTGCTGCTGATTCGCGTGGCCGGCCGATCCTTGC
GAAGATGCGGCAACGAATCC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 717; Mature: 716

Protein sequence:

>717_residues
MSRTRVVTPSLAVAGQARLSSLPGVGPKVADKFAARGILSVQDLWLHLPLRYEDRTRLTTIAQLQGGVPAQVEGRVEAVE
RGFRFRPVLRVAVSDASHGTLVLRFFHFRAAQVAQFAVGTRLRVFGTPKPGQHGWEIVHPSYRVLAPDEDAGLGDSLDPV
YPVLEGVGPATLRKLIGQALERLPPESALELLPPHWLQDERLPSLRAALLTMHRPPVGTDPQQLLAGGHPAQQRLAIEEL
LAHQLSLRRQRIALQRLHAPSLPGNGTLVQQLCKALPFQLTGAQQRVFEQIAHDLAHPSPMLRLVQGDVGSGKTVVAALA
AMLAVEQGKQVALAAPTELLAEQHLTNLRGWLEPLGIRIVWLAGKVTGKARAAVMAEVASGQAQVVVGTHALMQEAVVFH
DLALAIIDEQHRFGVHQRLALRDKGAAAGSVPHQLVMTATPIPRTLAMSAYADLDVSAIDELPPGRTPVQTIVLSAERRP
ELVERIRAACAEGRQAYWVCTLIEESEEPEKGAQGQQGGPPRIEAQAAEVTFEALSAQLPGVRVALVHGRMKPAEKQKAM
LDFKQGRSDLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQLRGRVGRGAAASSCVLLYQAPLSMMARQRLETMRQT
NDGFVIAEKDLELRGPGELLGTRQTGLASFRIADLARDAGLLPRVQVLAERLLDEAPEIADRVVERWIGGAVRYAAA

Sequences:

>Translated_717_residues
MSRTRVVTPSLAVAGQARLSSLPGVGPKVADKFAARGILSVQDLWLHLPLRYEDRTRLTTIAQLQGGVPAQVEGRVEAVE
RGFRFRPVLRVAVSDASHGTLVLRFFHFRAAQVAQFAVGTRLRVFGTPKPGQHGWEIVHPSYRVLAPDEDAGLGDSLDPV
YPVLEGVGPATLRKLIGQALERLPPESALELLPPHWLQDERLPSLRAALLTMHRPPVGTDPQQLLAGGHPAQQRLAIEEL
LAHQLSLRRQRIALQRLHAPSLPGNGTLVQQLCKALPFQLTGAQQRVFEQIAHDLAHPSPMLRLVQGDVGSGKTVVAALA
AMLAVEQGKQVALAAPTELLAEQHLTNLRGWLEPLGIRIVWLAGKVTGKARAAVMAEVASGQAQVVVGTHALMQEAVVFH
DLALAIIDEQHRFGVHQRLALRDKGAAAGSVPHQLVMTATPIPRTLAMSAYADLDVSAIDELPPGRTPVQTIVLSAERRP
ELVERIRAACAEGRQAYWVCTLIEESEEPEKGAQGQQGGPPRIEAQAAEVTFEALSAQLPGVRVALVHGRMKPAEKQKAM
LDFKQGRSDLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQLRGRVGRGAAASSCVLLYQAPLSMMARQRLETMRQT
NDGFVIAEKDLELRGPGELLGTRQTGLASFRIADLARDAGLLPRVQVLAERLLDEAPEIADRVVERWIGGAVRYAAA
>Mature_716_residues
SRTRVVTPSLAVAGQARLSSLPGVGPKVADKFAARGILSVQDLWLHLPLRYEDRTRLTTIAQLQGGVPAQVEGRVEAVER
GFRFRPVLRVAVSDASHGTLVLRFFHFRAAQVAQFAVGTRLRVFGTPKPGQHGWEIVHPSYRVLAPDEDAGLGDSLDPVY
PVLEGVGPATLRKLIGQALERLPPESALELLPPHWLQDERLPSLRAALLTMHRPPVGTDPQQLLAGGHPAQQRLAIEELL
AHQLSLRRQRIALQRLHAPSLPGNGTLVQQLCKALPFQLTGAQQRVFEQIAHDLAHPSPMLRLVQGDVGSGKTVVAALAA
MLAVEQGKQVALAAPTELLAEQHLTNLRGWLEPLGIRIVWLAGKVTGKARAAVMAEVASGQAQVVVGTHALMQEAVVFHD
LALAIIDEQHRFGVHQRLALRDKGAAAGSVPHQLVMTATPIPRTLAMSAYADLDVSAIDELPPGRTPVQTIVLSAERRPE
LVERIRAACAEGRQAYWVCTLIEESEEPEKGAQGQQGGPPRIEAQAAEVTFEALSAQLPGVRVALVHGRMKPAEKQKAML
DFKQGRSDLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQLRGRVGRGAAASSCVLLYQAPLSMMARQRLETMRQTN
DGFVIAEKDLELRGPGELLGTRQTGLASFRIADLARDAGLLPRVQVLAERLLDEAPEIADRVVERWIGGAVRYAAA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=700, Percent_Identity=58.2857142857143, Blast_Score=741, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=402, Percent_Identity=39.5522388059701, Blast_Score=254, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77581; Mature: 77450

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTRVVTPSLAVAGQARLSSLPGVGPKVADKFAARGILSVQDLWLHLPLRYEDRTRLTT
CCCCEECCCCHHHHCHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHEECCCCCCCCHHHHH
IAQLQGGVPAQVEGRVEAVERGFRFRPVLRVAVSDASHGTLVLRFFHFRAAQVAQFAVGT
HHHHCCCCCCCCCCHHHHHHCCCCCCHHHEEEECCCCCCEEEHHHHHHHHHHHHHHHHCC
RLRVFGTPKPGQHGWEIVHPSYRVLAPDEDAGLGDSLDPVYPVLEGVGPATLRKLIGQAL
EEEEEECCCCCCCCCEEECCCEEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
ERLPPESALELLPPHWLQDERLPSLRAALLTMHRPPVGTDPQQLLAGGHPAQQRLAIEEL
HHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHH
LAHQLSLRRQRIALQRLHAPSLPGNGTLVQQLCKALPFQLTGAQQRVFEQIAHDLAHPSP
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCH
MLRLVQGDVGSGKTVVAALAAMLAVEQGKQVALAAPTELLAEQHLTNLRGWLEPLGIRIV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEE
WLAGKVTGKARAAVMAEVASGQAQVVVGTHALMQEAVVFHDLALAIIDEQHRFGVHQRLA
EEECCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHH
LRDKGAAAGSVPHQLVMTATPIPRTLAMSAYADLDVSAIDELPPGRTPVQTIVLSAERRP
HHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCHHHHEECCCCCH
ELVERIRAACAEGRQAYWVCTLIEESEEPEKGAQGQQGGPPRIEAQAAEVTFEALSAQLP
HHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
GVRVALVHGRMKPAEKQKAMLDFKQGRSDLLVATTVIEVGVDVPNASLMIIENAERLGLA
CEEEEEEECCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCEEEEEECCHHCCHH
QLHQLRGRVGRGAAASSCVLLYQAPLSMMARQRLETMRQTNDGFVIAEKDLELRGPGELL
HHHHHHHHCCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHH
GTRQTGLASFRIADLARDAGLLPRVQVLAERLLDEAPEIADRVVERWIGGAVRYAAA
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
SRTRVVTPSLAVAGQARLSSLPGVGPKVADKFAARGILSVQDLWLHLPLRYEDRTRLTT
CCCEECCCCHHHHCHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHEECCCCCCCCHHHHH
IAQLQGGVPAQVEGRVEAVERGFRFRPVLRVAVSDASHGTLVLRFFHFRAAQVAQFAVGT
HHHHCCCCCCCCCCHHHHHHCCCCCCHHHEEEECCCCCCEEEHHHHHHHHHHHHHHHHCC
RLRVFGTPKPGQHGWEIVHPSYRVLAPDEDAGLGDSLDPVYPVLEGVGPATLRKLIGQAL
EEEEEECCCCCCCCCEEECCCEEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
ERLPPESALELLPPHWLQDERLPSLRAALLTMHRPPVGTDPQQLLAGGHPAQQRLAIEEL
HHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHH
LAHQLSLRRQRIALQRLHAPSLPGNGTLVQQLCKALPFQLTGAQQRVFEQIAHDLAHPSP
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCH
MLRLVQGDVGSGKTVVAALAAMLAVEQGKQVALAAPTELLAEQHLTNLRGWLEPLGIRIV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEE
WLAGKVTGKARAAVMAEVASGQAQVVVGTHALMQEAVVFHDLALAIIDEQHRFGVHQRLA
EEECCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHH
LRDKGAAAGSVPHQLVMTATPIPRTLAMSAYADLDVSAIDELPPGRTPVQTIVLSAERRP
HHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCHHHHEECCCCCH
ELVERIRAACAEGRQAYWVCTLIEESEEPEKGAQGQQGGPPRIEAQAAEVTFEALSAQLP
HHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
GVRVALVHGRMKPAEKQKAMLDFKQGRSDLLVATTVIEVGVDVPNASLMIIENAERLGLA
CEEEEEEECCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCEEEEEECCHHCCHH
QLHQLRGRVGRGAAASSCVLLYQAPLSMMARQRLETMRQTNDGFVIAEKDLELRGPGELL
HHHHHHHHCCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHH
GTRQTGLASFRIADLARDAGLLPRVQVLAERLLDEAPEIADRVVERWIGGAVRYAAA
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]