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The map label for this gene is ruvB [H]

Identifier: 78048833

GI number: 78048833

Start: 3742997

End: 3744037

Strand: Reverse

Name: ruvB [H]

Synonym: XCV3277

Alternate gene names: 78048833

Gene position: 3744037-3742997 (Counterclockwise)

Preceding gene: 78048834

Following gene: 78048832

Centisome position: 72.3

GC content: 66.19

Gene sequence:

>1041_bases
ATGACTGAGCAGCGCATCATCGCCAGCAGCTCCACCCGCGAAGACGACGCCGCCGATGCGAGCATTCGTCCCAAGCGCCT
GGCCGATTATCTCGGTCAGCAGCCGGTGCGCGAGCAGATGGAGATCTACATCCAGGCGGCCAAGGCGCGTGGCGAGGCGA
TGGATCATGTGCTGATCTTCGGGCCGCCCGGGCTCGGCAAGACCACGCTGAGTCACGTCATCGCCAACGAGCTGGGCGTG
AGCCTGCGCGTGACCTCTGGCCCGGTGATCGAAAAGGCCGGCGATCTGGCGGCGTTGCTCACCAACCTGCAGCCGCACGA
TGTGTTGTTCATCGACGAAATCCATCGCCTCTCGCCGGTGGTGGAAGAAGTGCTGTATCCGGCGATGGAAGATTTCCAGA
TCGACATCATGATCGGCGACGGCCCGGCCGCGCGCTCGATCAAGATCGACCTGCCGCCGTTCACCCTGATCGGTGCCACC
ACCCGTGCCGGCCTGCTCACCGCGCCCTTGCGCGACCGCTTCGGCATCGTGCAGCGGCTGGAATTCTATTCCCCGCAGGA
ATTGACCCGCATCGTGAGTCGCTCGGCGGCCATACTGGGCATCGACTGCACGCCCGAAGGCGCGGCGGAAATCGCACGCC
GCGCGCGCGGCACCCCGCGTATCGCCAACCGGCTGCTGCGTCGCGTGCGCGACTACGCCCAGGTCAAGGCGGCCGGGCAT
ATCGATCTGCCGGTGGCGCAGGCGGCCATGCAGATGCTGAAAGTGGATCCGGAAGGCTTTGACGAGCTCGACCGTCGCAT
GTTGCGCACCATCGTCGAACATTTCGATGGCGGCCCGGTCGGCGTGGAATCGCTGGCCGCCTCGCTGTCGGAGGAGCGCG
GCACGCTGGAAGACGTCATCGAGCCGTACCTGATCCAGCAGGGCTTTCTGATCCGCACGGCGCGCGGCCGGATGGTCACG
CCCAAGGCCTATCTGCATCTGGGCCTGAAGGTGCCGCGCGAGCGCGCCCCGGGCATCGGCGAACCGGGAGACCTGTTTTG
A

Upstream 100 bases:

>100_bases
GCGCGCCGCGCGCTTCGATGCCTTCTTCGCAGTGCTGCGCCAGGCCGAGCTTGATGTCTAGATGTTGGGCCATCCGCGCG
CGGCATGAGAAGATGGCCGG

Downstream 100 bases:

>100_bases
CGACGCTCTGCTGGTCGCCAACCTGGGCCGTCACGACCGAAATTCCGTGCCCATGACCATCGAATCCCCATTCTCCAATC
CCCAATCCCTGCCGGTATTC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTEQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIFGPPGLGKTTLSHVIANELGV
SLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGAT
TRAGLLTAPLRDRFGIVQRLEFYSPQELTRIVSRSAAILGIDCTPEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGH
IDLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVIEPYLIQQGFLIRTARGRMVT
PKAYLHLGLKVPRERAPGIGEPGDLF

Sequences:

>Translated_346_residues
MTEQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIFGPPGLGKTTLSHVIANELGV
SLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGAT
TRAGLLTAPLRDRFGIVQRLEFYSPQELTRIVSRSAAILGIDCTPEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGH
IDLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVIEPYLIQQGFLIRTARGRMVT
PKAYLHLGLKVPRERAPGIGEPGDLF
>Mature_345_residues
TEQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIFGPPGLGKTTLSHVIANELGVS
LRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATT
RAGLLTAPLRDRFGIVQRLEFYSPQELTRIVSRSAAILGIDCTPEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGHI
DLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVIEPYLIQQGFLIRTARGRMVTP
KAYLHLGLKVPRERAPGIGEPGDLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=328, Percent_Identity=68.9024390243902, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37946; Mature: 37815

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIF
CCCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
GPPGLGKTTLSHVIANELGVSLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPV
CCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
VEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATTRAGLLTAPLRDRFGIVQRL
HHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEECCCHHCCEEECCHHHHHHHHHHH
EFYSPQELTRIVSRSAAILGIDCTPEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGH
HHCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
IDLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVI
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHH
EPYLIQQGFLIRTARGRMVTPKAYLHLGLKVPRERAPGIGEPGDLF
HHHHHHCCCEEEECCCCEECCHHHHEECCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
TEQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIF
CCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
GPPGLGKTTLSHVIANELGVSLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPV
CCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
VEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATTRAGLLTAPLRDRFGIVQRL
HHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEECCCHHCCEEECCHHHHHHHHHHH
EFYSPQELTRIVSRSAAILGIDCTPEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGH
HHCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
IDLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVI
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHH
EPYLIQQGFLIRTARGRMVTPKAYLHLGLKVPRERAPGIGEPGDLF
HHHHHHCCCEEEECCCCEECCHHHHEECCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]