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The map label for this gene is cutC [H]

Identifier: 78048777

GI number: 78048777

Start: 3671417

End: 3672148

Strand: Reverse

Name: cutC [H]

Synonym: XCV3221

Alternate gene names: 78048777

Gene position: 3672148-3671417 (Counterclockwise)

Preceding gene: 78048778

Following gene: 78048774

Centisome position: 70.91

GC content: 66.8

Gene sequence:

>732_bases
ATGAGCGCGTTCGGGTTGGAGGTGGCTGCCGATTCGGTGGCCTCGGCATTGGCCGCGCAAGCAGGCGGTGCAATGCGCGT
GGAGCTGTGCGGCGGGCTGGATGGCGGTGGGCTGACACCATCGTTCGGCACGTTGGCGGTGGTGCGCGAGCGTTTGCGGA
TTCCGTTGTATGTGCTGATTCGTCCGCGCGTGGGCGACTTCGTGTTCGACGCTGCAGAAGTCGAGGTGATGCGCCGCGAT
GTGGAGCAGTGCGTGCGGCTTGGTTGCGATGGCGTGGTCCTTGGCGCGCTGGACCGGCATGGGCAGGTCGATCTGGCGAC
AATGCGCGTGTTGATGCAGGCAGCAGGGTCGTTGGGGGTGACGTTTCATCGTGCGATCGATGTCAGTGCCGATCCGTCGC
GTGTGCTGGAGGATGCGATCGCGCTGGGGTGCGAGCGGGTGCTGACCTCGGGTGCACGTGCGAGTGCGCTGGAGGGAGTC
GACACCATTGCCGCGTTGGTGCGGCAGGCAGCCGGGCGCATCGGCATCATGCCCGGTGCCGGGCTTTCCGAGCACAACAT
CCGCACCCTGCGGCAGCACACCGGCGCCCACGAATTCCATGCGTCGGCGCGTGGCGTGATCGCCGCCCAGGTGCCGTCGC
CGCACCCGTATATCCGCGATCTGGGCGGCGACTACCAACGGACCGATACCGCGCGGGTACAACGGATGGTAGACGCGTTG
CAACAGGCGTGA

Upstream 100 bases:

>100_bases
CGTTCGCGATCCAGAAGGGCTTCAGTTACGCGGTGTGCGACGCGCAGCGGCAGGATCTGCTGGTGCCTGGGCAGAGCCAT
TACACCAGCGAGCCGGCGGC

Downstream 100 bases:

>100_bases
AACGCGCGCAACGCCCCGTTCGCCAGGGAGGCGCTGCCCGCGTTGCGCAGGCACGCTGAGGGCGATGCTCGATGGGCTGC
TGCGCCTGTCGCGTTGGCTC

Product: copper homeostasis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSAFGLEVAADSVASALAAQAGGAMRVELCGGLDGGGLTPSFGTLAVVRERLRIPLYVLIRPRVGDFVFDAAEVEVMRRD
VEQCVRLGCDGVVLGALDRHGQVDLATMRVLMQAAGSLGVTFHRAIDVSADPSRVLEDAIALGCERVLTSGARASALEGV
DTIAALVRQAAGRIGIMPGAGLSEHNIRTLRQHTGAHEFHASARGVIAAQVPSPHPYIRDLGGDYQRTDTARVQRMVDAL
QQA

Sequences:

>Translated_243_residues
MSAFGLEVAADSVASALAAQAGGAMRVELCGGLDGGGLTPSFGTLAVVRERLRIPLYVLIRPRVGDFVFDAAEVEVMRRD
VEQCVRLGCDGVVLGALDRHGQVDLATMRVLMQAAGSLGVTFHRAIDVSADPSRVLEDAIALGCERVLTSGARASALEGV
DTIAALVRQAAGRIGIMPGAGLSEHNIRTLRQHTGAHEFHASARGVIAAQVPSPHPYIRDLGGDYQRTDTARVQRMVDAL
QQA
>Mature_242_residues
SAFGLEVAADSVASALAAQAGGAMRVELCGGLDGGGLTPSFGTLAVVRERLRIPLYVLIRPRVGDFVFDAAEVEVMRRDV
EQCVRLGCDGVVLGALDRHGQVDLATMRVLMQAAGSLGVTFHRAIDVSADPSRVLEDAIALGCERVLTSGARASALEGVD
TIAALVRQAAGRIGIMPGAGLSEHNIRTLRQHTGAHEFHASARGVIAAQVPSPHPYIRDLGGDYQRTDTARVQRMVDALQ
QA

Specific function: Involved in copper homeostasis [H]

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family [H]

Homologues:

Organism=Homo sapiens, GI148596990, Length=203, Percent_Identity=48.7684729064039, Blast_Score=193, Evalue=1e-49,
Organism=Escherichia coli, GI87081995, Length=198, Percent_Identity=44.4444444444444, Blast_Score=149, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17556905, Length=199, Percent_Identity=42.2110552763819, Blast_Score=154, Evalue=5e-38,
Organism=Drosophila melanogaster, GI21355415, Length=203, Percent_Identity=40.3940886699507, Blast_Score=145, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005627 [H]

Pfam domain/function: PF03932 CutC [H]

EC number: NA

Molecular weight: Translated: 25573; Mature: 25441

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFGLEVAADSVASALAAQAGGAMRVELCGGLDGGGLTPSFGTLAVVRERLRIPLYVLI
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEE
RPRVGDFVFDAAEVEVMRRDVEQCVRLGCDGVVLGALDRHGQVDLATMRVLMQAAGSLGV
ECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCE
TFHRAIDVSADPSRVLEDAIALGCERVLTSGARASALEGVDTIAALVRQAAGRIGIMPGA
EEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEECCCCC
GLSEHNIRTLRQHTGAHEFHASARGVIAAQVPSPHPYIRDLGGDYQRTDTARVQRMVDAL
CCCHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
QQA
HCC
>Mature Secondary Structure 
SAFGLEVAADSVASALAAQAGGAMRVELCGGLDGGGLTPSFGTLAVVRERLRIPLYVLI
CCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEE
RPRVGDFVFDAAEVEVMRRDVEQCVRLGCDGVVLGALDRHGQVDLATMRVLMQAAGSLGV
ECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCE
TFHRAIDVSADPSRVLEDAIALGCERVLTSGARASALEGVDTIAALVRQAAGRIGIMPGA
EEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEECCCCC
GLSEHNIRTLRQHTGAHEFHASARGVIAAQVPSPHPYIRDLGGDYQRTDTARVQRMVDAL
CCCHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
QQA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]