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The map label for this gene is pip [H]

Identifier: 78048690

GI number: 78048690

Start: 3553386

End: 3554471

Strand: Reverse

Name: pip [H]

Synonym: XCV3134

Alternate gene names: 78048690

Gene position: 3554471-3553386 (Counterclockwise)

Preceding gene: 78048691

Following gene: 78048688

Centisome position: 68.64

GC content: 66.39

Gene sequence:

>1086_bases
ATGCGAGGCGTTCGATCGAACCGGCTATCGGCCAGCGCCAACCGCGCATCCGGGCGCGCCCAAACCTGTGAAATTTGCCA
GTTAACGCCGCTCGGCGTGCTCGCTAGGCTCGGGGCTCATCATTGCCGTAGGCAGGCGCAGGTCATGCAGTGCACCGAGG
GTTACGTCGAATTCCGCGGCTACCGTACCTGGTACCGCATTACCGGCGACCTGTGCGCAGATGCCTGCCCGCTGTTGGTG
CTGCACGGCGGCCCCGGATGCACGCACGACTACGTGGACAGCTTCAAGGACCTGGCGGCCAACGGCCGCGCGGTGATCCA
CTACGACCAGCTGGGCAACGGCAACTCCACCCATCTGCGCAATGCCGAGCCAGGCTTCTGGACAGTGGGGCTGTTTCTGG
ACGAGCTGCAGACGCTGATCGCGCATCTGGGGCTGTCGCAGTACGCATTGCTGGGCCAGTCCTGGGGCGGAATGCTCGCC
GCCGAGCACGCCGTGCGCCGGCCGGCCAGCCTGCGAGCGCTGGTCATCGCCAATTCGCCCGCCTCGATGGGGTTGTGGCG
CGCGGCTGCGCTGCGTCTGCGCGCGCGCCTGCCTGACGATATCCAGGCCGCATTGGACGAGCACGAAGCCGCCGGTACGC
TGGACCATCCGGCCTACCGCGCAGCCAGTCAGGTGTTCTATGCGCAGCACGTATGTCGCGTGCTGCCGTGGCCTGCCGAG
GTCGCGCGGACGTTTGCCGCCATCGACGCCGACCCCACCGTGTATCACGCCATGAACGGCCCGACCGAATTCCACGTGGT
GGGCAGCTTGCGCAACTGGAGCATCATCGAGCGCCTGCACCGCATCACCGCACCCACGCTGGTGCTCTCTGGCAAGTACG
ACGAAGCCACGCCGGAAACCGTCGAGCCCTATGCGCGGTTGATCCCGGATGCGCGCTGGCACGTGTTCGCCAACTCCAGC
CACATGCCGCACGTGGAAGAACGCGCGGCGTGCATGCGCCTGGTCGGCAATTTCCTGGACGATCAGACACCGTGGCCCGG
TGGACAAATGCTGCGCTCCTCAGCACTGGCCAATCGCGCTGTTTGA

Upstream 100 bases:

>100_bases
AGTCCAGTGGCGCTGACAGATGCGATAGATGTGCTGATTCGAACTAACTATTTCGATCCAGGAGCGATGTCGAGTCGCGC
GATACCCAGCGCATTCGGCG

Downstream 100 bases:

>100_bases
GCGTGCAGTGTGGTGTGGCGATAGCCAGCGGGCCGATCAACTGCACTGCGTTTAGCTGCCTGCTTGCCGCGATGATGTCG
CTGTGGGTGGACACCATCAA

Product: prolyl aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MRGVRSNRLSASANRASGRAQTCEICQLTPLGVLARLGAHHCRRQAQVMQCTEGYVEFRGYRTWYRITGDLCADACPLLV
LHGGPGCTHDYVDSFKDLAANGRAVIHYDQLGNGNSTHLRNAEPGFWTVGLFLDELQTLIAHLGLSQYALLGQSWGGMLA
AEHAVRRPASLRALVIANSPASMGLWRAAALRLRARLPDDIQAALDEHEAAGTLDHPAYRAASQVFYAQHVCRVLPWPAE
VARTFAAIDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHRITAPTLVLSGKYDEATPETVEPYARLIPDARWHVFANSS
HMPHVEERAACMRLVGNFLDDQTPWPGGQMLRSSALANRAV

Sequences:

>Translated_361_residues
MRGVRSNRLSASANRASGRAQTCEICQLTPLGVLARLGAHHCRRQAQVMQCTEGYVEFRGYRTWYRITGDLCADACPLLV
LHGGPGCTHDYVDSFKDLAANGRAVIHYDQLGNGNSTHLRNAEPGFWTVGLFLDELQTLIAHLGLSQYALLGQSWGGMLA
AEHAVRRPASLRALVIANSPASMGLWRAAALRLRARLPDDIQAALDEHEAAGTLDHPAYRAASQVFYAQHVCRVLPWPAE
VARTFAAIDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHRITAPTLVLSGKYDEATPETVEPYARLIPDARWHVFANSS
HMPHVEERAACMRLVGNFLDDQTPWPGGQMLRSSALANRAV
>Mature_361_residues
MRGVRSNRLSASANRASGRAQTCEICQLTPLGVLARLGAHHCRRQAQVMQCTEGYVEFRGYRTWYRITGDLCADACPLLV
LHGGPGCTHDYVDSFKDLAANGRAVIHYDQLGNGNSTHLRNAEPGFWTVGLFLDELQTLIAHLGLSQYALLGQSWGGMLA
AEHAVRRPASLRALVIANSPASMGLWRAAALRLRARLPDDIQAALDEHEAAGTLDHPAYRAASQVFYAQHVCRVLPWPAE
VARTFAAIDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHRITAPTLVLSGKYDEATPETVEPYARLIPDARWHVFANSS
HMPHVEERAACMRLVGNFLDDQTPWPGGQMLRSSALANRAV

Specific function: Hydrolyzes L-prolinamide, L-proline-p-nitroanilide, L- alaninamide, L-methioninamide, piperidine-2-carboxamide and piperazine-2-carboxamide. Has a much lower activity towards piperazine-2-tert-butylcarboxamide. Does not hydrolyze dipeptides and D-prolinam

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005945
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.5.1.101 [H]

Molecular weight: Translated: 39729; Mature: 39729

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGVRSNRLSASANRASGRAQTCEICQLTPLGVLARLGAHHCRRQAQVMQCTEGYVEFRG
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YRTWYRITGDLCADACPLLVLHGGPGCTHDYVDSFKDLAANGRAVIHYDQLGNGNSTHLR
CEEEEEEEHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
NAEPGFWTVGLFLDELQTLIAHLGLSQYALLGQSWGGMLAAEHAVRRPASLRALVIANSP
CCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEECCC
ASMGLWRAAALRLRARLPDDIQAALDEHEAAGTLDHPAYRAASQVFYAQHVCRVLPWPAE
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
VARTFAAIDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHRITAPTLVLSGKYDEATPET
HHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCHH
VEPYARLIPDARWHVFANSSHMPHVEERAACMRLVGNFLDDQTPWPGGQMLRSSALANRA
HHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
V
C
>Mature Secondary Structure
MRGVRSNRLSASANRASGRAQTCEICQLTPLGVLARLGAHHCRRQAQVMQCTEGYVEFRG
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YRTWYRITGDLCADACPLLVLHGGPGCTHDYVDSFKDLAANGRAVIHYDQLGNGNSTHLR
CEEEEEEEHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
NAEPGFWTVGLFLDELQTLIAHLGLSQYALLGQSWGGMLAAEHAVRRPASLRALVIANSP
CCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEECCC
ASMGLWRAAALRLRARLPDDIQAALDEHEAAGTLDHPAYRAASQVFYAQHVCRVLPWPAE
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
VARTFAAIDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHRITAPTLVLSGKYDEATPET
HHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCHH
VEPYARLIPDARWHVFANSSHMPHVEERAACMRLVGNFLDDQTPWPGGQMLRSSALANRA
HHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA