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The map label for this gene is appC [H]

Identifier: 78048685

GI number: 78048685

Start: 3546155

End: 3547555

Strand: Reverse

Name: appC [H]

Synonym: XCV3129

Alternate gene names: 78048685

Gene position: 3547555-3546155 (Counterclockwise)

Preceding gene: 78048686

Following gene: 78048684

Centisome position: 68.51

GC content: 62.96

Gene sequence:

>1401_bases
ATGGACGCACTGCTGTTATCGCGGATCCAGTTCGGATTCGTCATTGCGTTCCACGTGTTGTTTCCGGCATTCACCATCGG
GCTTTCCAGCCTGCTGGCGTTTCTGGAATGGCGCTGGTTGCGCACGCGTCTGCCGGTCTGGCGCGAGCTGTATTTTTTCT
GGCAGAAGATCTTTGCCGTGTCCTTCGGCATGGGCGTGGTCAGCGGCATCGTGATGGCCTTCCAGTTCGGGGCCAACTGG
CCGGAATTGAGCCGCGTGGCCGGTGGCGTGATCGGGCCACTGCTGAGCTATGAAGTGCTCACCGCGTTCTTTCTGGAAGC
CAGTTTCCTGGGCGTGATGATGTTCGGCTGGGGTCGAATTTCCGAGCGCCTGCATTTCCTGGCCACCTGCATGGTGGCGC
TGGGCACGCTGTTTTCCACGTTCTGGATTCTTTCGTCCAATAGCTGGTTGCAGACCCCGGCCGGCTACGAGGTCATCGGC
GGCATCGTGCATCCGGTGGACTGGTTGCAGATCATCTTCAATCCCTCGTTCCCGTACCGGCTTGCGCACATGGCGCTTGG
CTCGTTCATCACCACCTGCTTCGTGGTGGGTGCAGTGGGCGCGTGGTATCTGCATCGTGGCGTACATCGCCAGGCAGGGC
TGCGCATGCTGAAGCTGGCCGTGGTGTTTGCCGCGATCGCCGTACCGCTGCAGATCGTCGTCGGCGACATGCATGGCTTG
AACACGCTCAAGCATCAGCCGATGAAGATCGCCGCGATGGAAGCGCACTGGCATGCCGAACAGCCGGGCGAGGGATTCCC
GCTGGTGGTGTTTGCGTTACCCAACGCACAGGCTGAGCGTAACGACTATGAGGTGGCGATTCCGCGCCTGGGCAGCCTGA
TTCTGACCCACCGCCCGGATGGCAGCATCGCGCCACTGACGTCGGTGCCGGCAAGCGAGCGCCCGCCGGTGACGCCGGTG
TTCTTCGCCTTCCGCATCATGGTGGGGATCGGCTCATTGATGCTGCTGGTGGCCTGGGTGTCTGCGTTCGCGTTATGGCG
CGGCAAGCTGGTGCAATGGCGCTGGTTGCTGGCGGTCTGGCGCTGGATGTTGCCGAGCGGCTTCATCGCGCTGATTTCCG
GCTGGTTCGTCACCGAAATCGGCCGGCAGCCCTATGTGGTCTACGGCTTGTTGCGCACCGCCGATGCGGTGGGCCCGCAG
TCTGCGCTGATGACCGCCATCTCGCTGGCGGTGTATGTGGCCGGCTACGCGTTCGTGTTCGGCTGGGGCATCTGGTACCT
GGTCAAGATCGGCAAGCAAGGCCCCACCCCACATGCCGACGCGCCGCATCTGGACCATGGCGAACACACGCCCGCACGCC
CGCTGTCGGCAGCGGATGCACCGATCGACGGAGCTGCATGA

Upstream 100 bases:

>100_bases
GTAGCGCAGCAGCGCGCGCGCGATCGCTCGATGCAATGCATTCCGGCGATCGCGCTGCGACCTGCGCGCCGACGATCACT
TTTTTCCTGGAGGGTTCTCC

Downstream 100 bases:

>100_bases
TGGAGATGAACAGCGTATTGCCGGTGGCGTGGTTTGCGGTGATCGGCTTCGGGGTGCTGATGTACGTGGTGCTGGACGGC
TTCGTGCTCGGCATCGGCAT

Product: quinol oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome bd-II oxidase subunit I [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MDALLLSRIQFGFVIAFHVLFPAFTIGLSSLLAFLEWRWLRTRLPVWRELYFFWQKIFAVSFGMGVVSGIVMAFQFGANW
PELSRVAGGVIGPLLSYEVLTAFFLEASFLGVMMFGWGRISERLHFLATCMVALGTLFSTFWILSSNSWLQTPAGYEVIG
GIVHPVDWLQIIFNPSFPYRLAHMALGSFITTCFVVGAVGAWYLHRGVHRQAGLRMLKLAVVFAAIAVPLQIVVGDMHGL
NTLKHQPMKIAAMEAHWHAEQPGEGFPLVVFALPNAQAERNDYEVAIPRLGSLILTHRPDGSIAPLTSVPASERPPVTPV
FFAFRIMVGIGSLMLLVAWVSAFALWRGKLVQWRWLLAVWRWMLPSGFIALISGWFVTEIGRQPYVVYGLLRTADAVGPQ
SALMTAISLAVYVAGYAFVFGWGIWYLVKIGKQGPTPHADAPHLDHGEHTPARPLSAADAPIDGAA

Sequences:

>Translated_466_residues
MDALLLSRIQFGFVIAFHVLFPAFTIGLSSLLAFLEWRWLRTRLPVWRELYFFWQKIFAVSFGMGVVSGIVMAFQFGANW
PELSRVAGGVIGPLLSYEVLTAFFLEASFLGVMMFGWGRISERLHFLATCMVALGTLFSTFWILSSNSWLQTPAGYEVIG
GIVHPVDWLQIIFNPSFPYRLAHMALGSFITTCFVVGAVGAWYLHRGVHRQAGLRMLKLAVVFAAIAVPLQIVVGDMHGL
NTLKHQPMKIAAMEAHWHAEQPGEGFPLVVFALPNAQAERNDYEVAIPRLGSLILTHRPDGSIAPLTSVPASERPPVTPV
FFAFRIMVGIGSLMLLVAWVSAFALWRGKLVQWRWLLAVWRWMLPSGFIALISGWFVTEIGRQPYVVYGLLRTADAVGPQ
SALMTAISLAVYVAGYAFVFGWGIWYLVKIGKQGPTPHADAPHLDHGEHTPARPLSAADAPIDGAA
>Mature_466_residues
MDALLLSRIQFGFVIAFHVLFPAFTIGLSSLLAFLEWRWLRTRLPVWRELYFFWQKIFAVSFGMGVVSGIVMAFQFGANW
PELSRVAGGVIGPLLSYEVLTAFFLEASFLGVMMFGWGRISERLHFLATCMVALGTLFSTFWILSSNSWLQTPAGYEVIG
GIVHPVDWLQIIFNPSFPYRLAHMALGSFITTCFVVGAVGAWYLHRGVHRQAGLRMLKLAVVFAAIAVPLQIVVGDMHGL
NTLKHQPMKIAAMEAHWHAEQPGEGFPLVVFALPNAQAERNDYEVAIPRLGSLILTHRPDGSIAPLTSVPASERPPVTPV
FFAFRIMVGIGSLMLLVAWVSAFALWRGKLVQWRWLLAVWRWMLPSGFIALISGWFVTEIGRQPYVVYGLLRTADAVGPQ
SALMTAISLAVYVAGYAFVFGWGIWYLVKIGKQGPTPHADAPHLDHGEHTPARPLSAADAPIDGAA

Specific function: Cytochrome oxidase subunit [H]

COG id: COG1271

COG function: function code C; Cytochrome bd-type quinol oxidase, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome ubiquinol oxidase subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1787212, Length=512, Percent_Identity=31.4453125, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI87081779, Length=318, Percent_Identity=32.0754716981132, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002585 [H]

Pfam domain/function: PF01654 Bac_Ubq_Cox [H]

EC number: 1.10.3.-

Molecular weight: Translated: 51547; Mature: 51547

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on diphenols and related substances as donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1658595; 8905232; 9278503; 8626304 [H]