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The map label for this gene is murA [H]

Identifier: 78048666

GI number: 78048666

Start: 3530002

End: 3531276

Strand: Reverse

Name: murA [H]

Synonym: XCV3110

Alternate gene names: 78048666

Gene position: 3531276-3530002 (Counterclockwise)

Preceding gene: 78048667

Following gene: 78048665

Centisome position: 68.19

GC content: 67.06

Gene sequence:

>1275_bases
ATGGCAAAAATCGTAGTGACCGGCGGCCAAGCGCTGCATGGCGAGGTCAATATTTCCGGCGCCAAGAATGCAGTGCTGCC
GATCCTGTGCGCCACCCTGCTGGCCGACGCGCCGGTGGAAATCAGCAACGTGCCGCACCTGCACGACGTGATCACCACGG
TGAAGCTGCTCAGCGAGCTGGGCGCGGAGGTCACCATCGACGAAGGCACGCTGGCCAAGGGCCGTTCGATCCTGGTCGAC
CCGCGCTCGGTCACCCATCAGGTTGCGCCGTACGAGCTGGTCAAGACCATGCGTGCCTCGATCCTGGTGTTGGGCCCGCT
GCTGGCGCGCTACGGCACCGCCGAAGTGTCGCTGCCCGGCGGTTGCGCGATCGGTTCGCGCCCGGTGGATCAGCACATCA
AGGGCCTGCAGGCACTGGGTGCCGACATCAGCGTGGAGAATGGCTACATCAAGGCCACCAGCCACGGGCGCCTGAAGGGC
GGCCGCTATGTGTTCGACATGGTCAGCGTCACCGGCACCGAGAACGTGCTGATGGCCGCCGTGCTCGCCGAAGGCACCAC
GGTGCTGGAAAACGCGGCGATGGAGCCGGAAGTTACCGACCTGGCCGACTGTCTGATCGCACTCGGTGCGCAGATCGAAG
GCGCCGGCACTCCACGCATCGTGGTGCAGGGCGTCGAGCGGCTGGGCGGCGGGCACCATGCGGTGCTGCCGGACCGCATC
GAAACCGGCACCTTCCTGGTCGCCGCGGCGATGACCGGCGGCAGCGTCACCGTGCGCCGCGCGCGCCCGGAAACGCTGGA
TGCAGTGCTGGACAAGCTGACCGAGGCCGGCGCCACCATCACCACCACCGCCGACAGCATCACGCTGGACATGCAGGGCA
AGCGTCCGCGCGCCGTCAGCCTGACCACCGCGCCGTACCCGGCGTTTCCCACCGACATGCAGGCGCAATTCATGGCGCTC
AACTGCGTGGCCGACGGGGTGGGCGTGATCAACGAAACCATCTTCGAAAACCGCTTCATGCACGTCAACGAGCTGCTGCG
CCTGGGCGCGGATATCCAGGTCGAAGGCCACACCGCCATCGTGCGCGGTGCCGAACGCCTGAGCGGCGCGCCAGTGATGG
CGACCGACCTGCGCGCATCGGCGTCGCTGATCCTGGCAGGCCTGGTCGCCGATGGCGACACCACCATCGATCGCATTTAC
CACCTGGACCGTGGCTACGAAAACATCGAGGAGAAGCTGGGGGCGCTGGGCGCGACCATCCAGCGCACCGCATGA

Upstream 100 bases:

>100_bases
GCTCGATCCCCGGTTCCACCGCGCGCCGCGTGCACCACGATCGATACGCGCCTTATTTCATTCCCGACATCCCTTCTACT
TTCGGATTTTTCAGATTCCC

Downstream 100 bases:

>100_bases
TCCTGCGCGGCCCTTTCACCACCCGGCGCAAGATCCTGCTCGGCGTGATCGTGCTGATCCTGGCGTGGCTGGCCTATGCC
TGGAGCGTGGGCATGGCCAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MAKIVVTGGQALHGEVNISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSELGAEVTIDEGTLAKGRSILVD
PRSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPGGCAIGSRPVDQHIKGLQALGADISVENGYIKATSHGRLKG
GRYVFDMVSVTGTENVLMAAVLAEGTTVLENAAMEPEVTDLADCLIALGAQIEGAGTPRIVVQGVERLGGGHHAVLPDRI
ETGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVSLTTAPYPAFPTDMQAQFMAL
NCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAIVRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIY
HLDRGYENIEEKLGALGATIQRTA

Sequences:

>Translated_424_residues
MAKIVVTGGQALHGEVNISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSELGAEVTIDEGTLAKGRSILVD
PRSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPGGCAIGSRPVDQHIKGLQALGADISVENGYIKATSHGRLKG
GRYVFDMVSVTGTENVLMAAVLAEGTTVLENAAMEPEVTDLADCLIALGAQIEGAGTPRIVVQGVERLGGGHHAVLPDRI
ETGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVSLTTAPYPAFPTDMQAQFMAL
NCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAIVRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIY
HLDRGYENIEEKLGALGATIQRTA
>Mature_423_residues
AKIVVTGGQALHGEVNISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSELGAEVTIDEGTLAKGRSILVDP
RSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPGGCAIGSRPVDQHIKGLQALGADISVENGYIKATSHGRLKGG
RYVFDMVSVTGTENVLMAAVLAEGTTVLENAAMEPEVTDLADCLIALGAQIEGAGTPRIVVQGVERLGGGHHAVLPDRIE
TGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVSLTTAPYPAFPTDMQAQFMALN
CVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAIVRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIYH
LDRGYENIEEKLGALGATIQRTA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=422, Percent_Identity=62.7962085308057, Blast_Score=520, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44382; Mature: 44250

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIVVTGGQALHGEVNISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSEL
CEEEEEECCCEEECEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHC
GAEVTIDEGTLAKGRSILVDPRSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPG
CCEEEECCCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
GCAIGSRPVDQHIKGLQALGADISVENGYIKATSHGRLKGGRYVFDMVSVTGTENVLMAA
CCCCCCCCHHHHHHHHHHHCCCEEECCCEEEECCCCCCCCCEEEEEEEEECCCCHHHHHH
VLAEGTTVLENAAMEPEVTDLADCLIALGAQIEGAGTPRIVVQGVERLGGGHHAVLPDRI
HHHCCCHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHCCCCEEECCCCC
ETGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVS
CCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCEEE
LTTAPYPAFPTDMQAQFMALNCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAI
EECCCCCCCCCCCHHHHEEEHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCHHE
VRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIYHLDRGYENIEEKLGALGATI
EECHHHHCCCCEEEHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCHH
QRTA
CCCC
>Mature Secondary Structure 
AKIVVTGGQALHGEVNISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSEL
EEEEEECCCEEECEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHC
GAEVTIDEGTLAKGRSILVDPRSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPG
CCEEEECCCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
GCAIGSRPVDQHIKGLQALGADISVENGYIKATSHGRLKGGRYVFDMVSVTGTENVLMAA
CCCCCCCCHHHHHHHHHHHCCCEEECCCEEEECCCCCCCCCEEEEEEEEECCCCHHHHHH
VLAEGTTVLENAAMEPEVTDLADCLIALGAQIEGAGTPRIVVQGVERLGGGHHAVLPDRI
HHHCCCHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHCCCCEEECCCCC
ETGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVS
CCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCEEE
LTTAPYPAFPTDMQAQFMALNCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAI
EECCCCCCCCCCCHHHHEEEHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCHHE
VRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIYHLDRGYENIEEKLGALGATI
EECHHHHCCCCEEEHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCHH
QRTA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]