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The map label for this gene is napA [H]

Identifier: 78048522

GI number: 78048522

Start: 3372212

End: 3373477

Strand: Reverse

Name: napA [H]

Synonym: XCV2966

Alternate gene names: 78048522

Gene position: 3373477-3372212 (Counterclockwise)

Preceding gene: 78048523

Following gene: 78048519

Centisome position: 65.14

GC content: 63.9

Gene sequence:

>1266_bases
ATGACCACTCCGCAGATGTCGGTGTATTTCTTTTTGCAGGCTGCCGCGATTTTGTTGGTGTGCCGGCTGGTCGGCATGCT
GGCCAAGCGCCTCGGGCAACCGCAGGTGGTGGGCGAAATGATTGCCGGCGTGATGCTGGGGCCCTCGTTGTTCGGCTTGC
TGGCGCCGGGCGCGCAGGCGGCCCTGTTCCCCAAGCAGACCATGGACGTGCTGTATGTGTTCGCGCAGTTCGGCGTGGGC
CTGTACATGTTCCTGGTCGGAACCGATTTCCGCGGCGACCACTTTCGCGCGCGCTATCGCAGTGCCATGAGCGTGTCGAT
GGCGGGCATCGCGGTGCCGTTCCTGCTGGCATTTGCCATGTGCCCATGGTTGATCAACGTGCAGGGCCTGTTTTCGGAAA
AGGCCAAGCTGGCCGAAGCGTCGCTGTTCCTGGGCGCGGCCATTGCGATCACCGCCTTCCCGATGCTGGCGCGCATCATC
CACGAACGCGGTCTGACCAATAGCCCCTTGGGCACCTTGGCGCTGACCGCTGGCGCGTTCGACGATGCCGCAGCGTGGTG
CATTTTGGCCGTGGTGCTGGCCAGTTTCGGCGGCAGTTGGGGCAGTGCCTACCTGGCCATCGGCGGCGGCATCGGCTATG
CGGTCTTCATGATTTTCGTCGGCCGGCATCTGCTCAAGCGGCTGGCCGATCATGTGGTGCCCGGCCAGCCGCTGAGCAAC
AGTGTCCTGGCGGTGGTGCTGATCCTGTTCTGCATCAGCGCCTGGGCGATGGATGCGATCGGCATCCATGCGGTGTTCGG
CGGTTTCCTGCTCGGTGTCTGCCTGCCCAGGGGCGCACTGACCGAGAAGCTGCGCGAGATGATGCGGCCGTTCGTCGTGG
TGTTGCTGCTGCCGATGTTCTTCACCTATTCGGGCTTGAAAACCCAGCTCAGCGTATTGCTGCAGCCGCAGATCATGCTG
GCGGGCGTGGCGATCCTGGCCGCGTCGTTCATCGGCAAGGGCGTGGCCTGCTGGGCCGCGGCGCGTGCGACCGGCGAGAA
CAACCGCGACGCGATGGCGATCGGTTCGCTGATGAATGCACGCGGGCTGATGGAGCTGATCATCATCAATATCGGCTTGC
AGGCGGGTGTGATCGAACAGGGCTTGTTCTCGGTGCTGGTGCTGATGGCGATCCTGTCCACGCTGATGGCCACGCCGTTG
TTCAACTGGATCATGCGTCGCCACGCCCATGTGAGCGACGCGGTGCCGAGCCTGCAGTCGCGGTGA

Upstream 100 bases:

>100_bases
AGCGCGCAGGTGGCTCAGATCGCCATCGGCCGCCGCACGCTACCGAAGTGCGGCAGGTCCGGTTACGATCTGCGCACTTT
TCAGGGATGTCGCCGCACGC

Downstream 100 bases:

>100_bases
TCGGCGCGCGACTGCCCGCAGGTGCGGGCAGTGCACTGGCGGCGTGTGCGGCCGGGCGTTGCGTCAACGCCCCAGCGGCA
ACTGCACGCTGGCCAGCAGG

Product: monovalent cation:proton antiporter-2 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTTPQMSVYFFLQAAAILLVCRLVGMLAKRLGQPQVVGEMIAGVMLGPSLFGLLAPGAQAALFPKQTMDVLYVFAQFGVG
LYMFLVGTDFRGDHFRARYRSAMSVSMAGIAVPFLLAFAMCPWLINVQGLFSEKAKLAEASLFLGAAIAITAFPMLARII
HERGLTNSPLGTLALTAGAFDDAAAWCILAVVLASFGGSWGSAYLAIGGGIGYAVFMIFVGRHLLKRLADHVVPGQPLSN
SVLAVVLILFCISAWAMDAIGIHAVFGGFLLGVCLPRGALTEKLREMMRPFVVVLLLPMFFTYSGLKTQLSVLLQPQIML
AGVAILAASFIGKGVACWAAARATGENNRDAMAIGSLMNARGLMELIIINIGLQAGVIEQGLFSVLVLMAILSTLMATPL
FNWIMRRHAHVSDAVPSLQSR

Sequences:

>Translated_421_residues
MTTPQMSVYFFLQAAAILLVCRLVGMLAKRLGQPQVVGEMIAGVMLGPSLFGLLAPGAQAALFPKQTMDVLYVFAQFGVG
LYMFLVGTDFRGDHFRARYRSAMSVSMAGIAVPFLLAFAMCPWLINVQGLFSEKAKLAEASLFLGAAIAITAFPMLARII
HERGLTNSPLGTLALTAGAFDDAAAWCILAVVLASFGGSWGSAYLAIGGGIGYAVFMIFVGRHLLKRLADHVVPGQPLSN
SVLAVVLILFCISAWAMDAIGIHAVFGGFLLGVCLPRGALTEKLREMMRPFVVVLLLPMFFTYSGLKTQLSVLLQPQIML
AGVAILAASFIGKGVACWAAARATGENNRDAMAIGSLMNARGLMELIIINIGLQAGVIEQGLFSVLVLMAILSTLMATPL
FNWIMRRHAHVSDAVPSLQSR
>Mature_420_residues
TTPQMSVYFFLQAAAILLVCRLVGMLAKRLGQPQVVGEMIAGVMLGPSLFGLLAPGAQAALFPKQTMDVLYVFAQFGVGL
YMFLVGTDFRGDHFRARYRSAMSVSMAGIAVPFLLAFAMCPWLINVQGLFSEKAKLAEASLFLGAAIAITAFPMLARIIH
ERGLTNSPLGTLALTAGAFDDAAAWCILAVVLASFGGSWGSAYLAIGGGIGYAVFMIFVGRHLLKRLADHVVPGQPLSNS
VLAVVLILFCISAWAMDAIGIHAVFGGFLLGVCLPRGALTEKLREMMRPFVVVLLLPMFFTYSGLKTQLSVLLQPQIMLA
GVAILAASFIGKGVACWAAARATGENNRDAMAIGSLMNARGLMELIIINIGLQAGVIEQGLFSVLVLMAILSTLMATPLF
NWIMRRHAHVSDAVPSLQSR

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=405, Percent_Identity=31.358024691358, Blast_Score=183, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 44904; Mature: 44772

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure 
TTPQMSVYFFLQAAAILLVCRLVGMLAKRLGQPQVVGEMIAGVMLGPSLFGLLAPGAQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
ALFPKQTMDVLYVFAQFGVGLYMFLVGTDFRGDHFRARYRSAMSVSMAGIAVPFLLAFAM
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CPWLINVQGLFSEKAKLAEASLFLGAAIAITAFPMLARIIHERGLTNSPLGTLALTAGAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCC
DDAAAWCILAVVLASFGGSWGSAYLAIGGGIGYAVFMIFVGRHLLKRLADHVVPGQPLSN
HHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
SVLAVVLILFCISAWAMDAIGIHAVFGGFLLGVCLPRGALTEKLREMMRPFVVVLLLPMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FTYSGLKTQLSVLLQPQIMLAGVAILAASFIGKGVACWAAARATGENNRDAMAIGSLMNA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHH
RGLMELIIINIGLQAGVIEQGLFSVLVLMAILSTLMATPLFNWIMRRHAHVSDAVPSLQS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]