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The map label for this gene is pkn1 [H]

Identifier: 78048166

GI number: 78048166

Start: 2942262

End: 2944247

Strand: Reverse

Name: pkn1 [H]

Synonym: XCV2610

Alternate gene names: 78048166

Gene position: 2944247-2942262 (Counterclockwise)

Preceding gene: 78048168

Following gene: 78048165

Centisome position: 56.86

GC content: 70.24

Gene sequence:

>1986_bases
ATGGCAGCGTGGGCAATGGTCGCGCTGAGGGCGACTGGCAAAATTCCTGCGCAGCCAGCAGGCGGGCGCGGCCGCGGTGC
GGAATCGGCATCTGGCACGCCTACGCTCCGGTTCCTGCGCGCCCGCCTTGCCCGCCCGAGCGCTGCTCGCTGCGTTTTGT
TGGCCGCTCTTAGCCTGTGCGCCTGTTCGCGCACGCCCACGCCCGCGCCTGCGGTCGCGCCGCAACCGGCACCTGCCGCC
GTGCCGAGCAAGCCGAACGTTTCCATCGGTGGCGAAGAATCCGCCGAAACCGTGGCGCAATGGCAACCGCCGGTGGTGGA
GTTGGGCGACGAGCCCCTGGCGCAGGTGCGCAAGCGTGCCGACCAGGCATTGCGGGAAGACCGCCTGTATCGCGACGCCG
GTGATGCGATCCCGTTGTATCTGGCGATCCAGCAGCGCGCCGGTGGCAAGGATGCAGCCAGCCGGCGTGGCCTGGAGCAG
GCGCGTGACCGGTTGCTCGAACGCGGCGCGGCGCTGATCGCACAAACCGAGCGCCAGGATGACGCGTTGGAGCAGGCGCG
TGAGGTGGCCTTCGTCGCGCTTGCCCTTGCGCCACAGGACCCGAAGGTGCGCGCACTGCAGCGCGAGGTGGAAACCGCGC
AGCGCGTGCTGGCGTTCAACCGCGCCGGCGAAGAAGACCTGCGCGGCGGGCGGCTGGGCGAAGACGGCAATGGCGCGCTG
GTGAATTTTCGCGATGCCGCGCAATTGGATCCCGACAACCCGCGCACCCGGCAGGGCCTGGCCGCCGTGGAAAGCGGCCT
GCTGGAGCGCGCCGAACGGGCGGCGCAGGCGAGCGACTTCATCGGTGCCCGTTACTGGCTGCAGATGGCGGGGCAGGTAC
GCGATCGTGCGCCGACCATCGCCGATGCGCGCGCGCGGGTGGAACGCGTGCGCCGGGCGCAGATCGCGGCGTTGCACGAC
GCCGGTCTGCACGATCTGACCTCGCCGCGCGGGCTCAAGGCGGCCGGCGAGAAGCTTGCCGAAGTGTTGCGCATCGCCGA
CCCCGGAGACCCAGTGGCCGGCGATCTGCGCCGCCGGCTGGAACTGGCCACGCATTACGGCAGCTTCCGTCCCGGGCAGG
TGTTCACCGACGGGCTCAAGGTCGGCGGGCGCGGGCCGCAGATGATCGTGGTGCCGCATGGCGCATTCCAGATGGGAGCC
GGCGATGCGGAGCCGGGCGCTTCCGACAACGAGCGCCCCGCCCATTACGTGCGCTTCGCACGCGGCTTTGCGTTGTCGAT
CACCGAGGTCACGGTTGCCGAGTTCCGCCAGTTCGTCGATGCCACCGGCGCACGCCCGCGTGCCACCCGGCGTGGGCATT
CGGTGGTTTACGACGAGCGCAGCGGCAACTTCATCCGCCGCAGCGGCGTGGATTGGCAGTCCGACTACAACGGCGCCCAG
GCCGCGCCCAACAGCCCGGTGATGCACGTCAGCATTCGCGACGCCGAAGCGTATGCGAGCTGGCTGTCGGAACAGACCGG
CCGCCATTACCACGTGCCCAGTGAGGCCGAGTTCGAGTATGCGGTCCGTGCCGGCACCACCGGACGTTACCCGTGGGGCA
ACGCGGGCTCGCCGCCGGCCGACGCCGGTAATTTCACCGGCGGCAACGACGTTTCGCGCAGCGGCCGGCACTGGAACAAC
GGCTTCGTCGGCTACGGCGATGGCTTCTGGGGTCCGGCGCCGGTCGGCAGTTTTCGCGCCAACGCCTGGGGTCTGCACGA
CATGGGCGGCAACCTGAGCGAATGGGTGGCCGACTGCTGGCACGCCAGCTACCGGCGTGCACCGGCCGATGGCGCTGCCT
GGTACAACCCGGGCTGCCGGCAACGCATGATCCGTGGCGGCAGCTGGGCCAATTCGCCGCAGCAGACGCGCGCGGCCTGG
CGGCAGTCGCAGGACTCGGACACCACCAGTGCCCGTATCGGCTTTCGCGTGGCACGCGGAATCTAG

Upstream 100 bases:

>100_bases
AAGGGTTTGCGCAGAGCGCGCAGAATAGCCTAACGTCGCGATCGCCTGTCGTGCGGCAGAGCACTGGAAGGAGCAGGTGG
TGGGTGAGTGCGGTGACCGG

Downstream 100 bases:

>100_bases
CGACGACCTACGGCGGATGGGCGCGTCGATCGTGCGGTTCGTGACTGCAGGCTTCGGCTTGCCGTCGCTGTCGCCGCGAG
CGCTTTCGGCTCGGCCCTAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MAAWAMVALRATGKIPAQPAGGRGRGAESASGTPTLRFLRARLARPSAARCVLLAALSLCACSRTPTPAPAVAPQPAPAA
VPSKPNVSIGGEESAETVAQWQPPVVELGDEPLAQVRKRADQALREDRLYRDAGDAIPLYLAIQQRAGGKDAASRRGLEQ
ARDRLLERGAALIAQTERQDDALEQAREVAFVALALAPQDPKVRALQREVETAQRVLAFNRAGEEDLRGGRLGEDGNGAL
VNFRDAAQLDPDNPRTRQGLAAVESGLLERAERAAQASDFIGARYWLQMAGQVRDRAPTIADARARVERVRRAQIAALHD
AGLHDLTSPRGLKAAGEKLAEVLRIADPGDPVAGDLRRRLELATHYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFQMGA
GDAEPGASDNERPAHYVRFARGFALSITEVTVAEFRQFVDATGARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQ
AAPNSPVMHVSIRDAEAYASWLSEQTGRHYHVPSEAEFEYAVRAGTTGRYPWGNAGSPPADAGNFTGGNDVSRSGRHWNN
GFVGYGDGFWGPAPVGSFRANAWGLHDMGGNLSEWVADCWHASYRRAPADGAAWYNPGCRQRMIRGGSWANSPQQTRAAW
RQSQDSDTTSARIGFRVARGI

Sequences:

>Translated_661_residues
MAAWAMVALRATGKIPAQPAGGRGRGAESASGTPTLRFLRARLARPSAARCVLLAALSLCACSRTPTPAPAVAPQPAPAA
VPSKPNVSIGGEESAETVAQWQPPVVELGDEPLAQVRKRADQALREDRLYRDAGDAIPLYLAIQQRAGGKDAASRRGLEQ
ARDRLLERGAALIAQTERQDDALEQAREVAFVALALAPQDPKVRALQREVETAQRVLAFNRAGEEDLRGGRLGEDGNGAL
VNFRDAAQLDPDNPRTRQGLAAVESGLLERAERAAQASDFIGARYWLQMAGQVRDRAPTIADARARVERVRRAQIAALHD
AGLHDLTSPRGLKAAGEKLAEVLRIADPGDPVAGDLRRRLELATHYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFQMGA
GDAEPGASDNERPAHYVRFARGFALSITEVTVAEFRQFVDATGARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQ
AAPNSPVMHVSIRDAEAYASWLSEQTGRHYHVPSEAEFEYAVRAGTTGRYPWGNAGSPPADAGNFTGGNDVSRSGRHWNN
GFVGYGDGFWGPAPVGSFRANAWGLHDMGGNLSEWVADCWHASYRRAPADGAAWYNPGCRQRMIRGGSWANSPQQTRAAW
RQSQDSDTTSARIGFRVARGI
>Mature_660_residues
AAWAMVALRATGKIPAQPAGGRGRGAESASGTPTLRFLRARLARPSAARCVLLAALSLCACSRTPTPAPAVAPQPAPAAV
PSKPNVSIGGEESAETVAQWQPPVVELGDEPLAQVRKRADQALREDRLYRDAGDAIPLYLAIQQRAGGKDAASRRGLEQA
RDRLLERGAALIAQTERQDDALEQAREVAFVALALAPQDPKVRALQREVETAQRVLAFNRAGEEDLRGGRLGEDGNGALV
NFRDAAQLDPDNPRTRQGLAAVESGLLERAERAAQASDFIGARYWLQMAGQVRDRAPTIADARARVERVRRAQIAALHDA
GLHDLTSPRGLKAAGEKLAEVLRIADPGDPVAGDLRRRLELATHYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFQMGAG
DAEPGASDNERPAHYVRFARGFALSITEVTVAEFRQFVDATGARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQA
APNSPVMHVSIRDAEAYASWLSEQTGRHYHVPSEAEFEYAVRAGTTGRYPWGNAGSPPADAGNFTGGNDVSRSGRHWNNG
FVGYGDGFWGPAPVGSFRANAWGLHDMGGNLSEWVADCWHASYRRAPADGAAWYNPGCRQRMIRGGSWANSPQQTRAAWR
QSQDSDTTSARIGFRVARGI

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth. Phosphorylates incG, a inclusion-membrane protein required for the modification of the nascent chlamydial inclusio

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=300, Percent_Identity=30.3333333333333, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI257470977, Length=296, Percent_Identity=30.0675675675676, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI257470975, Length=285, Percent_Identity=29.8245614035088, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI194248087, Length=294, Percent_Identity=30.6122448979592, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI194248088, Length=309, Percent_Identity=30.42071197411, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI226437577, Length=183, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI194248090, Length=225, Percent_Identity=30.6666666666667, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20130397, Length=303, Percent_Identity=29.3729372937294, Blast_Score=90, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 71210; Mature: 71079

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAWAMVALRATGKIPAQPAGGRGRGAESASGTPTLRFLRARLARPSAARCVLLAALSLC
CCHHHEEHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
ACSRTPTPAPAVAPQPAPAAVPSKPNVSIGGEESAETVAQWQPPVVELGDEPLAQVRKRA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHH
DQALREDRLYRDAGDAIPLYLAIQQRAGGKDAASRRGLEQARDRLLERGAALIAQTERQD
HHHHHHHHHHHHCCCCCEEEEEEEHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCHHH
DALEQAREVAFVALALAPQDPKVRALQREVETAQRVLAFNRAGEEDLRGGRLGEDGNGAL
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCE
VNFRDAAQLDPDNPRTRQGLAAVESGLLERAERAAQASDFIGARYWLQMAGQVRDRAPTI
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ADARARVERVRRAQIAALHDAGLHDLTSPRGLKAAGEKLAEVLRIADPGDPVAGDLRRRL
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ELATHYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFQMGAGDAEPGASDNERPAHYVRFA
HHHHHCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHH
RGFALSITEVTVAEFRQFVDATGARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQ
CCCEEEHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEECCCCCEEECCCCCCCCCCCCCC
AAPNSPVMHVSIRDAEAYASWLSEQTGRHYHVPSEAEFEYAVRAGTTGRYPWGNAGSPPA
CCCCCCEEEEEECCHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCCCC
DAGNFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRANAWGLHDMGGNLSEWVADCW
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHH
HASYRRAPADGAAWYNPGCRQRMIRGGSWANSPQQTRAAWRQSQDSDTTSARIGFRVARG
HHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEEHHCC
I
C
>Mature Secondary Structure 
AAWAMVALRATGKIPAQPAGGRGRGAESASGTPTLRFLRARLARPSAARCVLLAALSLC
CHHHEEHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
ACSRTPTPAPAVAPQPAPAAVPSKPNVSIGGEESAETVAQWQPPVVELGDEPLAQVRKRA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHH
DQALREDRLYRDAGDAIPLYLAIQQRAGGKDAASRRGLEQARDRLLERGAALIAQTERQD
HHHHHHHHHHHHCCCCCEEEEEEEHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCHHH
DALEQAREVAFVALALAPQDPKVRALQREVETAQRVLAFNRAGEEDLRGGRLGEDGNGAL
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCE
VNFRDAAQLDPDNPRTRQGLAAVESGLLERAERAAQASDFIGARYWLQMAGQVRDRAPTI
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ADARARVERVRRAQIAALHDAGLHDLTSPRGLKAAGEKLAEVLRIADPGDPVAGDLRRRL
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ELATHYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFQMGAGDAEPGASDNERPAHYVRFA
HHHHHCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHH
RGFALSITEVTVAEFRQFVDATGARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQ
CCCEEEHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEECCCCCEEECCCCCCCCCCCCCC
AAPNSPVMHVSIRDAEAYASWLSEQTGRHYHVPSEAEFEYAVRAGTTGRYPWGNAGSPPA
CCCCCCEEEEEECCHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCCCC
DAGNFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRANAWGLHDMGGNLSEWVADCW
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHH
HASYRRAPADGAAWYNPGCRQRMIRGGSWANSPQQTRAAWRQSQDSDTTSARIGFRVARG
HHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEEHHCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9784136; 14500499 [H]