Click here to switch to the map view.

The map label for this gene is cmk [H]

Identifier: 78048053

GI number: 78048053

Start: 2818494

End: 2819177

Strand: Reverse

Name: cmk [H]

Synonym: XCV2497

Alternate gene names: 78048053

Gene position: 2819177-2818494 (Counterclockwise)

Preceding gene: 78048060

Following gene: 78048052

Centisome position: 54.44

GC content: 66.08

Gene sequence:

>684_bases
ATGACCGACCTGTCGCCCGTTCTCACCATCGATGGCCCTTCCGGTGCCGGCAAGGGCACCGTGAGCCGGATCGTGGCCGC
CCGGCTGGGCTGGCATTACCTCGATTCGGGTGCGCTGTATCGCGCGGTGGGTGTGGCGGCGAGCTGGGCCGACCTGGATG
TCTCCGACCCGGCAGCGCTGGTGCGTTGCACCTTCGACACCAGGGTGGAGTTCGACGATGCGGGCGAGGCAGGGCTGCGC
GTGCTGGTCAATGGCGCAGATGCGACCAGTGAGCTGCGCCTGGAAACGACCGGCGCGCTGGCCTCGGCCATTGCCGCCAT
TCCCGAGGTGCGCAGCGCCCTGAAAGAGCGCCAACGCGCATTCAGGCGCGCCCCCGGCCTGGTTGCCGACGGGCGCGACA
TGGGCACGGTGATCTTCCCCGATGCGGCCTACAAAGTGTTTCTGACCGCCAGTGCCGAAGAACGTGCGGGCCGTCGCCAT
AAACAGTTGATGGAAAAGGGTGTTTCGGTTATCTTTGACGACCTGCTGCGCGAGATCATGGCCCGTGATGCCCGTGATGC
GCAGCGGGTGGTGGCGCCATTGCGGCCGGCCGAAGACGCCGTGCTGATCGATACCAGCGGAATGGGAATCGAAGATGTCG
TCCAGCGTGTGGTCGGGTTGCTCGCAGACCGTGCGCCGTTGTAA

Upstream 100 bases:

>100_bases
CGGCGATTCTAACCGGCTTTTCGTCGTGCTTTCAAGTGGTTGCAGCGCGATCGCTGCGAGCGGCGCTACACTACGCGCTG
ATGACCTTCCGGAAACCTGA

Downstream 100 bases:

>100_bases
GCGTTTGGCAAGCGGGTTTGTCCCGCCGACCGTAAGGCGTTCCAAAGCTCCGTCGCGCATCCTGCGTGGCGGTTCTATGA
CTTCCAACCGACTTGCTGTC

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAALVRCTFDTRVEFDDAGEAGLR
VLVNGADATSELRLETTGALASAIAAIPEVRSALKERQRAFRRAPGLVADGRDMGTVIFPDAAYKVFLTASAEERAGRRH
KQLMEKGVSVIFDDLLREIMARDARDAQRVVAPLRPAEDAVLIDTSGMGIEDVVQRVVGLLADRAPL

Sequences:

>Translated_227_residues
MTDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAALVRCTFDTRVEFDDAGEAGLR
VLVNGADATSELRLETTGALASAIAAIPEVRSALKERQRAFRRAPGLVADGRDMGTVIFPDAAYKVFLTASAEERAGRRH
KQLMEKGVSVIFDDLLREIMARDARDAQRVVAPLRPAEDAVLIDTSGMGIEDVVQRVVGLLADRAPL
>Mature_226_residues
TDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAALVRCTFDTRVEFDDAGEAGLRV
LVNGADATSELRLETTGALASAIAAIPEVRSALKERQRAFRRAPGLVADGRDMGTVIFPDAAYKVFLTASAEERAGRRHK
QLMEKGVSVIFDDLLREIMARDARDAQRVVAPLRPAEDAVLIDTSGMGIEDVVQRVVGLLADRAPL

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787139, Length=218, Percent_Identity=51.8348623853211, Blast_Score=215, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003136
- InterPro:   IPR011994 [H]

Pfam domain/function: PF02224 Cytidylate_kin [H]

EC number: =2.7.4.14 [H]

Molecular weight: Translated: 24198; Mature: 24067

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAAL
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEE
VRCTFDTRVEFDDAGEAGLRVLVNGADATSELRLETTGALASAIAAIPEVRSALKERQRA
EEEECCCEECCCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
FRRAPGLVADGRDMGTVIFPDAAYKVFLTASAEERAGRRHKQLMEKGVSVIFDDLLREIM
HHHCCCCEECCCCCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARDARDAQRVVAPLRPAEDAVLIDTSGMGIEDVVQRVVGLLADRAPL
HCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAAL
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEE
VRCTFDTRVEFDDAGEAGLRVLVNGADATSELRLETTGALASAIAAIPEVRSALKERQRA
EEEECCCEECCCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
FRRAPGLVADGRDMGTVIFPDAAYKVFLTASAEERAGRRHKQLMEKGVSVIFDDLLREIM
HHHCCCCEECCCCCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARDARDAQRVVAPLRPAEDAVLIDTSGMGIEDVVQRVVGLLADRAPL
HCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]