Click here to switch to the map view.

The map label for this gene is hmrR2 [H]

Identifier: 78047891

GI number: 78047891

Start: 2665500

End: 2665979

Strand: Reverse

Name: hmrR2 [H]

Synonym: XCV2335

Alternate gene names: 78047891

Gene position: 2665979-2665500 (Counterclockwise)

Preceding gene: 78047892

Following gene: 78047885

Centisome position: 51.48

GC content: 63.12

Gene sequence:

>480_bases
ATGAACATCGGTGAAGCGTCCACGGCATCGAAGGTCTCGGCCAAGATGATCCGCTACTACGAGGAAATCGGCCTGATCCC
GCCGGCGAACCGAACCGACGCGGGCTACCGCGCCTACACGCAGTCCGATGTGCACCGGCTGCATTTCATCCGGCGCGCGC
GTGATCTCGGATTCTCGGTCGCCGAGATCAGGGACCTGCTGGGCCTTTGGAACAACAAGTCGCGCCAGAGCAGCGACGTC
AAGCGCCTGGCCCAAGAGCACATCGAGGACCTTGAGCGACGCATCGAGAGCATGTTGCAGATGGCCGAGACGCTTAAGAC
GCTGATCAGTTGCTGCGCGGGCGATGACCGGCCTGACTGCCCCATCCTGCATACCCTTGAGCAGCCGGACGACAACGATG
GAGAACCCGAGGCGCGCACGGGGGCAGTGCAACGCCGACGGCGCACTCCTGCATCAAAGAAGGGCTCACGAGCACGCTGA

Upstream 100 bases:

>100_bases
GTCGAGCGTGTTCGTGCTCGGCAACGCACTGCGCCTGCGCCGCTTCCAGCCGCCGCTGGATACGGCCTCCGCGGCTTCAC
ACTGAGAAAGGAGGACGACC

Downstream 100 bases:

>100_bases
GGACGTCGGGCGGGACAGGAACTCTCCATCAGGATCAGTGAAATGTTCCTGCCGCTGAGCGACTAGAGCGTCCTTAGCCA
GCGAGAGATACGGGTTTCCT

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNIGEASTASKVSAKMIRYYEEIGLIPPANRTDAGYRAYTQSDVHRLHFIRRARDLGFSVAEIRDLLGLWNNKSRQSSDV
KRLAQEHIEDLERRIESMLQMAETLKTLISCCAGDDRPDCPILHTLEQPDDNDGEPEARTGAVQRRRRTPASKKGSRAR

Sequences:

>Translated_159_residues
MNIGEASTASKVSAKMIRYYEEIGLIPPANRTDAGYRAYTQSDVHRLHFIRRARDLGFSVAEIRDLLGLWNNKSRQSSDV
KRLAQEHIEDLERRIESMLQMAETLKTLISCCAGDDRPDCPILHTLEQPDDNDGEPEARTGAVQRRRRTPASKKGSRAR
>Mature_159_residues
MNIGEASTASKVSAKMIRYYEEIGLIPPANRTDAGYRAYTQSDVHRLHFIRRARDLGFSVAEIRDLLGLWNNKSRQSSDV
KRLAQEHIEDLERRIESMLQMAETLKTLISCCAGDDRPDCPILHTLEQPDDNDGEPEARTGAVQRRRRTPASKKGSRAR

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=126, Percent_Identity=41.2698412698413, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1789687, Length=129, Percent_Identity=37.984496124031, Blast_Score=88, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 18037; Mature: 18037

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGEASTASKVSAKMIRYYEEIGLIPPANRTDAGYRAYTQSDVHRLHFIRRARDLGFSV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
AEIRDLLGLWNNKSRQSSDVKRLAQEHIEDLERRIESMLQMAETLKTLISCCAGDDRPDC
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILHTLEQPDDNDGEPEARTGAVQRRRRTPASKKGSRAR
CEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNIGEASTASKVSAKMIRYYEEIGLIPPANRTDAGYRAYTQSDVHRLHFIRRARDLGFSV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
AEIRDLLGLWNNKSRQSSDVKRLAQEHIEDLERRIESMLQMAETLKTLISCCAGDDRPDC
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILHTLEQPDDNDGEPEARTGAVQRRRRTPASKKGSRAR
CEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]