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The map label for this gene is trxA [C]

Identifier: 78047869

GI number: 78047869

Start: 2646404

End: 2646724

Strand: Reverse

Name: trxA [C]

Synonym: XCV2313

Alternate gene names: 78047869

Gene position: 2646724-2646404 (Counterclockwise)

Preceding gene: 78047871

Following gene: 78047868

Centisome position: 51.11

GC content: 62.31

Gene sequence:

>321_bases
ATGCTTCAAGAGCTGAACAACGACAATTTCGATACGACGCTCGGCCAGGTGCCCGGCGTCTATGCCGTCCGCTTCTGGGC
CGAATGGTGCGGCCCGTGCAGGGTGATGTCCCCGATCTTCAAGGACGTCGCCCGCGACATGCAGGATCGCGCGCACTTCG
GCGAGGTCGATATCGACCAGGCCCCGGAATTGGCTGGCCGCTTCGGCGTGCAGAGCATCCCAACGGTGGTGCTGTTCAAG
GATGGCCAGGTGATCGACCGGATGACCGGCGCAGCGCCCAAGCCCAACGTCCTTCGCTTCATCAACAACCACCTCGATTG
A

Upstream 100 bases:

>100_bases
CGGCAGCCATCCCTCCCATCCGCTGCTCAACCAAGCCTCTCTGCTTGCAGCGATCCGCACTGGCTGCGCCAGTGACTCCT
TTCCAACTTCAGGACCCCCC

Downstream 100 bases:

>100_bases
ACCGGACGGTGCGACCGCTCGGCATCACCGCGTCGGCCGTAGCGCACCTGCAGCCCCCCGACCGCCCATAGAGAACAACA
CCAATGACCCATGTAAGAGT

Product: putative thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MLQELNNDNFDTTLGQVPGVYAVRFWAEWCGPCRVMSPIFKDVARDMQDRAHFGEVDIDQAPELAGRFGVQSIPTVVLFK
DGQVIDRMTGAAPKPNVLRFINNHLD

Sequences:

>Translated_106_residues
MLQELNNDNFDTTLGQVPGVYAVRFWAEWCGPCRVMSPIFKDVARDMQDRAHFGEVDIDQAPELAGRFGVQSIPTVVLFK
DGQVIDRMTGAAPKPNVLRFINNHLD
>Mature_106_residues
MLQELNNDNFDTTLGQVPGVYAVRFWAEWCGPCRVMSPIFKDVARDMQDRAHFGEVDIDQAPELAGRFGVQSIPTVVLFK
DGQVIDRMTGAAPKPNVLRFINNHLD

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI5031973, Length=76, Percent_Identity=36.8421052631579, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87082331, Length=101, Percent_Identity=38.6138613861386, Blast_Score=93, Evalue=3e-21,
Organism=Escherichia coli, GI1788936, Length=83, Percent_Identity=45.7831325301205, Blast_Score=91, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI212646193, Length=83, Percent_Identity=33.7349397590361, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321648, Length=94, Percent_Identity=31.9148936170213, Blast_Score=68, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319925, Length=71, Percent_Identity=39.4366197183099, Blast_Score=64, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323072, Length=86, Percent_Identity=31.3953488372093, Blast_Score=62, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573567, Length=68, Percent_Identity=38.2352941176471, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11920; Mature: 11920

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQELNNDNFDTTLGQVPGVYAVRFWAEWCGPCRVMSPIFKDVARDMQDRAHFGEVDIDQ
CCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
APELAGRFGVQSIPTVVLFKDGQVIDRMTGAAPKPNVLRFINNHLD
CHHHHHHCCCCCCCEEEEECCCCHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MLQELNNDNFDTTLGQVPGVYAVRFWAEWCGPCRVMSPIFKDVARDMQDRAHFGEVDIDQ
CCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
APELAGRFGVQSIPTVVLFKDGQVIDRMTGAAPKPNVLRFINNHLD
CHHHHHHCCCCCCCEEEEECCCCHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7021558 [H]