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The map label for this gene is virA [H]

Identifier: 78047701

GI number: 78047701

Start: 2461463

End: 2463919

Strand: Reverse

Name: virA [H]

Synonym: XCV2145

Alternate gene names: 78047701

Gene position: 2463919-2461463 (Counterclockwise)

Preceding gene: 78047702

Following gene: 78047700

Centisome position: 47.58

GC content: 66.38

Gene sequence:

>2457_bases
GTGAGGTGGGCGACGATCTTCAGCGCCGTGCTGCTGGCGGGGCTGATCTTCTTCAGCCTGTGCATGGCGGCGCTGGATCG
CGACACGCAGCGTTACGGTCATGCGTTGGACGCATTGGACGCGCTGGACATGGTCGATACCAATCTGGACAACGACGTGC
TGAAGGCACGCATTGGCCTGTTGCGCGACTACGATTCGCTGGTGAGCGGCGATGCCCGCGCACGCGACATCTTGCAGCAC
TTGCGCCACCTGGCCGATCACGACCCTGCGTTGTTCCGGGCGATCGCGGCGCTGGACGCCGACTACAACGAGAAATCGCT
GCAGCGGGAACTGTTCAAATCGCAGAACTCGCTGCTGTCCAATTCGCTGGCCTACTTCTGGAGCGAGAGCAGCGCGCAGA
TCCGGCAAGGCGAAGATCCCGCTGAGGCGCGCGCAGCGAGCATGCTGGCGAGCGCGGTACAACGCCTGAGCCTGGACACG
ACCGGTGATGCAGTGGCACTGGCACGCCGACGCCTGGACGAAGCGGCACAACGCACAACCAGCGCGCCACTGCTCCCGCA
TGGACGCATGCTGCTGAAGCTGCTGCCGGAGACAGACACCACCATCCGCCGCATGCGTCCGATCGCTTCGCTGGCCTCGT
ATGGACAGCTCAAGACGTATCTGCAACAGCAGCATGCCAGCCAGCAGGCCACTGCACGCCAGGTTCGCTTCCTGTTGCTG
GCATTGGCCGTCGTCATGTTGGGCGCCTTGCTGTACCTGGGCAAGCTGCTGCGGCAACGCGCGCGGGTGTTACGTCGACG
CGCGGAATTCGATCGCTTGATGGTCGCGGTGTCGCGCCGCCTGGTGGCCAACGATCGCCATCAGCTGGACGCCGGCATCG
AGGCCGGACTGGTGCGGTTGGTGAAGTGGGCCAAGCTGCCAGGCGCTCGCCTGGGCCTGGTCCCCGTCGGCAGCGACGCG
CGGATCTGGCCCGATCCGCAGGACGACACCTTCCGCGCGATGCTTGCCGCGCTGGCATCCACCCAACCGATCGCCGCCAG
CGATGTGCTGGTCGTCGACGCCAACGGCACCGTCGCCGTGTTGGGCACGCCCGAACGCGTGCGCGACGCACAGTGGCTGT
GCCTGCGGCAACACGCAGACGCGGGGACGGTCGCGCTGCTGTGCTTGCGGCTGCCGCCACGCGCCCCGCGCCGCGATCGC
GGCCTGGCGACAGTGGCCGAACTGTTGCCGCAGCTGCATATCGCGCTCGACACCCTGTTCGATGCGCTGGAGCGGCGACG
ACTCGAAGACGAAGCGCTGGCACTGGAACATCGCCTGGAACTGGCCCGACGGATGGAAACGCTGGGGACCATGGCCAGCG
GTATCTCGCACAACTTCAACAACATCGTCGGCGCGATCCGCGGTAATGCCGAGATCGCACTGTCCAAACTGGACCCGCAC
TCGCCGGCCTCGGAGCACCTGCTCGAGATCAGCCATACCACCGCCCACGCCTACGATCTGATCGAATCCATCCTCAGCTT
CGGCCGCGTGCAGAACTACAACGTGCAGCCGGTCGAACTGAACGCCTTGCTGCAGGGCGCGGTCTCGCTGCTGTCGGTCT
CGCTGCCCTCGACGGTGGCCATCGACCTGCAGCAGGAGCAGGAGCCGCTGCACGCGTTGGGCAATCCGGCGCAACTGCAG
CAGATCATTCTGAATCTGGCCAGCAACGCTGCGCAGGCGATGGACATGCGCGGCACGGTCACGATCCAACTGTCCGCCGG
AAAAGGCACTGCAACCGACGGCACGCCCCGGCGCATCGCGCAGTTGCGTGTGGGCGATCACGGCATCGGCATCCCGCCCG
ACCAACTGGATCGCATCTTCGATCTGTTCTTCACTACCCGCAGCGGCGGCACCGGGTTGGGGTTGGCAACGGTTCGCAAG
ATCATCGATAACCACGACGGGCGGATCGACGTGGACAGCGCACTAGGTGTCGGCACGACCTTCGTGGTCGAGCTGCCGCT
GCGCACGGGCATCACAGCCGCGCCCCAGGCCGCTCCCCTGCCGAAGACGCGCTCGCGCCATGCGAGCTTGCTGTTGTTGT
GCGACGACGCGGCCGAGCTCGACCGCCTGGAAGAAATGCTGGCCGCACTCGGGCACGAACCGGTCGGCATGTTGGAGCTG
CCGGCCGCCGTCGCGATGGCGGCTGCCGATCCGGCGCGCTTCGATGGCGTGTTGCTCAAGCGCGATCGCGCCGGCGATGC
CGAACAGGCCATCGGCGCGCTGCACGCCGCGGCACCCACGCTGCCGCTGATCCTCGCCACACGTGCGAGCCTGGCGACAC
GCAAGGGTTTGGGCGGCGCCATCGCCGAGATCATTGCGCAGCCGTTCGATCTTGGCGCGCTGGCCATGGCGCTGGAACGT
GCACTGGGTCGCACGCTAGAAGTTACAACGCAGGATGAAGGCACCCCTGCTCTGTGA

Upstream 100 bases:

>100_bases
TGGGCGTCACACTGAGCCCGGCGGATGTGGCCGACATTGCCGCATTTCTGCAGACATTGACCGGCAAGCACCAAGGCCGG
CAGTTGACGGCGCCGGCGCC

Downstream 100 bases:

>100_bases
CAAATGAAACACAGTCGCTGCGGATCGACACCGGAACGTAGCGCGGGCTGCCTAGCGTAGCGGATGCCCAGGCGCAGCAG
ACCGCCTGCATTCCACTACG

Product: two-component VirA-like sensor kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 818; Mature: 818

Protein sequence:

>818_residues
MRWATIFSAVLLAGLIFFSLCMAALDRDTQRYGHALDALDALDMVDTNLDNDVLKARIGLLRDYDSLVSGDARARDILQH
LRHLADHDPALFRAIAALDADYNEKSLQRELFKSQNSLLSNSLAYFWSESSAQIRQGEDPAEARAASMLASAVQRLSLDT
TGDAVALARRRLDEAAQRTTSAPLLPHGRMLLKLLPETDTTIRRMRPIASLASYGQLKTYLQQQHASQQATARQVRFLLL
ALAVVMLGALLYLGKLLRQRARVLRRRAEFDRLMVAVSRRLVANDRHQLDAGIEAGLVRLVKWAKLPGARLGLVPVGSDA
RIWPDPQDDTFRAMLAALASTQPIAASDVLVVDANGTVAVLGTPERVRDAQWLCLRQHADAGTVALLCLRLPPRAPRRDR
GLATVAELLPQLHIALDTLFDALERRRLEDEALALEHRLELARRMETLGTMASGISHNFNNIVGAIRGNAEIALSKLDPH
SPASEHLLEISHTTAHAYDLIESILSFGRVQNYNVQPVELNALLQGAVSLLSVSLPSTVAIDLQQEQEPLHALGNPAQLQ
QIILNLASNAAQAMDMRGTVTIQLSAGKGTATDGTPRRIAQLRVGDHGIGIPPDQLDRIFDLFFTTRSGGTGLGLATVRK
IIDNHDGRIDVDSALGVGTTFVVELPLRTGITAAPQAAPLPKTRSRHASLLLLCDDAAELDRLEEMLAALGHEPVGMLEL
PAAVAMAAADPARFDGVLLKRDRAGDAEQAIGALHAAAPTLPLILATRASLATRKGLGGAIAEIIAQPFDLGALAMALER
ALGRTLEVTTQDEGTPAL

Sequences:

>Translated_818_residues
MRWATIFSAVLLAGLIFFSLCMAALDRDTQRYGHALDALDALDMVDTNLDNDVLKARIGLLRDYDSLVSGDARARDILQH
LRHLADHDPALFRAIAALDADYNEKSLQRELFKSQNSLLSNSLAYFWSESSAQIRQGEDPAEARAASMLASAVQRLSLDT
TGDAVALARRRLDEAAQRTTSAPLLPHGRMLLKLLPETDTTIRRMRPIASLASYGQLKTYLQQQHASQQATARQVRFLLL
ALAVVMLGALLYLGKLLRQRARVLRRRAEFDRLMVAVSRRLVANDRHQLDAGIEAGLVRLVKWAKLPGARLGLVPVGSDA
RIWPDPQDDTFRAMLAALASTQPIAASDVLVVDANGTVAVLGTPERVRDAQWLCLRQHADAGTVALLCLRLPPRAPRRDR
GLATVAELLPQLHIALDTLFDALERRRLEDEALALEHRLELARRMETLGTMASGISHNFNNIVGAIRGNAEIALSKLDPH
SPASEHLLEISHTTAHAYDLIESILSFGRVQNYNVQPVELNALLQGAVSLLSVSLPSTVAIDLQQEQEPLHALGNPAQLQ
QIILNLASNAAQAMDMRGTVTIQLSAGKGTATDGTPRRIAQLRVGDHGIGIPPDQLDRIFDLFFTTRSGGTGLGLATVRK
IIDNHDGRIDVDSALGVGTTFVVELPLRTGITAAPQAAPLPKTRSRHASLLLLCDDAAELDRLEEMLAALGHEPVGMLEL
PAAVAMAAADPARFDGVLLKRDRAGDAEQAIGALHAAAPTLPLILATRASLATRKGLGGAIAEIIAQPFDLGALAMALER
ALGRTLEVTTQDEGTPAL
>Mature_818_residues
MRWATIFSAVLLAGLIFFSLCMAALDRDTQRYGHALDALDALDMVDTNLDNDVLKARIGLLRDYDSLVSGDARARDILQH
LRHLADHDPALFRAIAALDADYNEKSLQRELFKSQNSLLSNSLAYFWSESSAQIRQGEDPAEARAASMLASAVQRLSLDT
TGDAVALARRRLDEAAQRTTSAPLLPHGRMLLKLLPETDTTIRRMRPIASLASYGQLKTYLQQQHASQQATARQVRFLLL
ALAVVMLGALLYLGKLLRQRARVLRRRAEFDRLMVAVSRRLVANDRHQLDAGIEAGLVRLVKWAKLPGARLGLVPVGSDA
RIWPDPQDDTFRAMLAALASTQPIAASDVLVVDANGTVAVLGTPERVRDAQWLCLRQHADAGTVALLCLRLPPRAPRRDR
GLATVAELLPQLHIALDTLFDALERRRLEDEALALEHRLELARRMETLGTMASGISHNFNNIVGAIRGNAEIALSKLDPH
SPASEHLLEISHTTAHAYDLIESILSFGRVQNYNVQPVELNALLQGAVSLLSVSLPSTVAIDLQQEQEPLHALGNPAQLQ
QIILNLASNAAQAMDMRGTVTIQLSAGKGTATDGTPRRIAQLRVGDHGIGIPPDQLDRIFDLFFTTRSGGTGLGLATVRK
IIDNHDGRIDVDSALGVGTTFVVELPLRTGITAAPQAAPLPKTRSRHASLLLLCDDAAELDRLEEMLAALGHEPVGMLEL
PAAVAMAAADPARFDGVLLKRDRAGDAEQAIGALHAAAPTLPLILATRASLATRKGLGGAIAEIIAQPFDLGALAMALER
ALGRTLEVTTQDEGTPAL

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=30.1204819277108, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788549, Length=235, Percent_Identity=32.3404255319149, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=27.3408239700375, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790300, Length=247, Percent_Identity=31.1740890688259, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI48994928, Length=264, Percent_Identity=28.030303030303, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081816, Length=353, Percent_Identity=27.1954674220963, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786912, Length=356, Percent_Identity=27.247191011236, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1789149, Length=271, Percent_Identity=27.3062730627306, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=29.1845493562232, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786600, Length=246, Percent_Identity=24.7967479674797, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=214, Percent_Identity=27.1028037383178, Blast_Score=63, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88449; Mature: 88449

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00059 ADH_ZINC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWATIFSAVLLAGLIFFSLCMAALDRDTQRYGHALDALDALDMVDTNLDNDVLKARIGL
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LRDYDSLVSGDARARDILQHLRHLADHDPALFRAIAALDADYNEKSLQRELFKSQNSLLS
HHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
NSLAYFWSESSAQIRQGEDPAEARAASMLASAVQRLSLDTTGDAVALARRRLDEAAQRTT
HHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
SAPLLPHGRMLLKLLPETDTTIRRMRPIASLASYGQLKTYLQQQHASQQATARQVRFLLL
CCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAVVMLGALLYLGKLLRQRARVLRRRAEFDRLMVAVSRRLVANDRHQLDAGIEAGLVRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VKWAKLPGARLGLVPVGSDARIWPDPQDDTFRAMLAALASTQPIAASDVLVVDANGTVAV
HHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEE
LGTPERVRDAQWLCLRQHADAGTVALLCLRLPPRAPRRDRGLATVAELLPQLHIALDTLF
ECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DALERRRLEDEALALEHRLELARRMETLGTMASGISHNFNNIVGAIRGNAEIALSKLDPH
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCC
SPASEHLLEISHTTAHAYDLIESILSFGRVQNYNVQPVELNALLQGAVSLLSVSLPSTVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
IDLQQEQEPLHALGNPAQLQQIILNLASNAAQAMDMRGTVTIQLSAGKGTATDGTPRRIA
EECHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHH
QLRVGDHGIGIPPDQLDRIFDLFFTTRSGGTGLGLATVRKIIDNHDGRIDVDSALGVGTT
HHEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCEE
FVVELPLRTGITAAPQAAPLPKTRSRHASLLLLCDDAAELDRLEEMLAALGHEPVGMLEL
EEEEECHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHH
PAAVAMAAADPARFDGVLLKRDRAGDAEQAIGALHAAAPTLPLILATRASLATRKGLGGA
HHHHHHHHCCCHHHCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHH
IAEIIAQPFDLGALAMALERALGRTLEVTTQDEGTPAL
HHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCC
>Mature Secondary Structure
MRWATIFSAVLLAGLIFFSLCMAALDRDTQRYGHALDALDALDMVDTNLDNDVLKARIGL
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LRDYDSLVSGDARARDILQHLRHLADHDPALFRAIAALDADYNEKSLQRELFKSQNSLLS
HHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
NSLAYFWSESSAQIRQGEDPAEARAASMLASAVQRLSLDTTGDAVALARRRLDEAAQRTT
HHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
SAPLLPHGRMLLKLLPETDTTIRRMRPIASLASYGQLKTYLQQQHASQQATARQVRFLLL
CCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAVVMLGALLYLGKLLRQRARVLRRRAEFDRLMVAVSRRLVANDRHQLDAGIEAGLVRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VKWAKLPGARLGLVPVGSDARIWPDPQDDTFRAMLAALASTQPIAASDVLVVDANGTVAV
HHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEE
LGTPERVRDAQWLCLRQHADAGTVALLCLRLPPRAPRRDRGLATVAELLPQLHIALDTLF
ECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DALERRRLEDEALALEHRLELARRMETLGTMASGISHNFNNIVGAIRGNAEIALSKLDPH
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCC
SPASEHLLEISHTTAHAYDLIESILSFGRVQNYNVQPVELNALLQGAVSLLSVSLPSTVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
IDLQQEQEPLHALGNPAQLQQIILNLASNAAQAMDMRGTVTIQLSAGKGTATDGTPRRIA
EECHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHH
QLRVGDHGIGIPPDQLDRIFDLFFTTRSGGTGLGLATVRKIIDNHDGRIDVDSALGVGTT
HHEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCEE
FVVELPLRTGITAAPQAAPLPKTRSRHASLLLLCDDAAELDRLEEMLAALGHEPVGMLEL
EEEEECHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHH
PAAVAMAAADPARFDGVLLKRDRAGDAEQAIGALHAAAPTLPLILATRASLATRKGLGGA
HHHHHHHHCCCHHHCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHH
IAEIIAQPFDLGALAMALERALGRTLEVTTQDEGTPAL
HHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2796735; 2194232; 11743193; 11743194 [H]