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The map label for this gene is ampC1 [H]

Identifier: 78047669

GI number: 78047669

Start: 2423965

End: 2425338

Strand: Reverse

Name: ampC1 [H]

Synonym: XCV2113

Alternate gene names: 78047669

Gene position: 2425338-2423965 (Counterclockwise)

Preceding gene: 78047673

Following gene: 78047665

Centisome position: 46.84

GC content: 64.63

Gene sequence:

>1374_bases
ATGAAGACAATTGCGATGATGCTGCTGGCTACCGCGCTGAGCATGGCCGGCACGGCCCGCGCGACGGGAACCACACCGCC
GGCGTCAGCCACGGCCGAATTGGCGCGCGAGGCCGCTGCGTTTTTCAAGGACAGCCAGCCGGGCGGCGTGGTGCTGGTGA
CGCGCGGCGATCAGGTGCTGCTGCGCCGGGCCTACGGCATGGCGGACATCGAAAATGGCGTGGCCATGCAACCGGACGCG
GCAATGCGGCTGGCTTCGGTCAGCAAGCAGTTCACCGCCATGGCGGTACTGCAACTGGTGCAGGCGGGCAAGCTGCAACT
GGATACCTGCCTGGAGTCAGTGGACCCGGCGCTGAGCGGCCCGCTCGCCAAGGTCACCGTGCAGCAACTGCTCACGCATA
CCTCCGGCATCAAGAATGTCAGCAGCATCGCTGCCTCGCGCGCCGCGCGACGGGAAGACACCGATGCGCGGAGCCTGATG
AACTATTTCAAGGACCTGCCGCTGGAGTTTGCTGCGGGCACGCGCTTTCGCTACAGCAACTCCAACTACATCGTGCTGAC
CTATCTGATCGAACGTATCACTGCTCAGCCCTACCCGGTCTATATGCAGCAGTCGCTGTTCCAGCCGCTGGGCATGCTGC
ATACCCGCTACGATGACCATCTCACCGTGATCGCCCAACGCGCGCATGGCTATCGCCGCGCGCAGGGCCAGTTGCAGAAC
GCCGACTTCATCAGCATGTCGCAGCCGCAAGGCGCGGGCGGTCTGATCAGCACGGTGGACGATCTGGCGATCTGGCACCG
CGCATTGCGCGACGGCTTGCCGGTGTCGGCATCGCTGCTGGCGCAGGCGATGCGCAAGACCACGTTGGCCGATGGCAGCG
CCTCGCCCTACGGCTTCGGCTGGATCATCGGCCAGGTAAACGGCATGGCCGACGTGGAGCATGGCGGCTTCATCAACGGC
TTCAACAGCTATGTGATGCGGGTGACGCAGCCGGACGTCTTCGTGACCGTATTGACCAATGCCGAGTTCCTGGATCCGAC
CAACCTGAGCGTGCGTCTGGCCGCCATCGCCGCCGGGCATGCCTATGCGGCGACGGTCGCGCTGCGCAGCCAGGACCGCG
CATGGCTGGGCCGTTATCGCTTTGCTGCAGATGATGTCCGCGTGCTTGCGGAAGTGGACGGCGCGCTGCAACTGCAGCGC
GAGGGAGAAGACCCGGTTGCCGTGCTGCCGCATGCCGACGGCCGTTACTACCTGGGCGAGAGCCTGGATGCGTTGAGCTT
CAACAACGACGGCAATGGCAACGCAGTCATGACCATGCACGACCGCTTGATGGGTGACAACAGCGGCACTCGCGAACCGA
CCGGGGACAACTGA

Upstream 100 bases:

>100_bases
GTCGACCGTTCGATGCCTGTCTCGACCGCACGTCATGCATCGCTGGGCGATGCACGGCTCCGCTTCCAAGCTGCGCTCCA
TCCACTGAAGGAGCAGGTGT

Downstream 100 bases:

>100_bases
CAAGCGGCTGCGCGGCTGCCCTCCGGCGGAATCGGTGCACAGAGTGGGCATATGCCACACGCATGCCCCGTGGCTCGCGT
GCGCCATCGGCACTGATCTG

Product: beta-lactamase precursor

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKTIAMMLLATALSMAGTARATGTTPPASATAELAREAAAFFKDSQPGGVVLVTRGDQVLLRRAYGMADIENGVAMQPDA
AMRLASVSKQFTAMAVLQLVQAGKLQLDTCLESVDPALSGPLAKVTVQQLLTHTSGIKNVSSIAASRAARREDTDARSLM
NYFKDLPLEFAAGTRFRYSNSNYIVLTYLIERITAQPYPVYMQQSLFQPLGMLHTRYDDHLTVIAQRAHGYRRAQGQLQN
ADFISMSQPQGAGGLISTVDDLAIWHRALRDGLPVSASLLAQAMRKTTLADGSASPYGFGWIIGQVNGMADVEHGGFING
FNSYVMRVTQPDVFVTVLTNAEFLDPTNLSVRLAAIAAGHAYAATVALRSQDRAWLGRYRFAADDVRVLAEVDGALQLQR
EGEDPVAVLPHADGRYYLGESLDALSFNNDGNGNAVMTMHDRLMGDNSGTREPTGDN

Sequences:

>Translated_457_residues
MKTIAMMLLATALSMAGTARATGTTPPASATAELAREAAAFFKDSQPGGVVLVTRGDQVLLRRAYGMADIENGVAMQPDA
AMRLASVSKQFTAMAVLQLVQAGKLQLDTCLESVDPALSGPLAKVTVQQLLTHTSGIKNVSSIAASRAARREDTDARSLM
NYFKDLPLEFAAGTRFRYSNSNYIVLTYLIERITAQPYPVYMQQSLFQPLGMLHTRYDDHLTVIAQRAHGYRRAQGQLQN
ADFISMSQPQGAGGLISTVDDLAIWHRALRDGLPVSASLLAQAMRKTTLADGSASPYGFGWIIGQVNGMADVEHGGFING
FNSYVMRVTQPDVFVTVLTNAEFLDPTNLSVRLAAIAAGHAYAATVALRSQDRAWLGRYRFAADDVRVLAEVDGALQLQR
EGEDPVAVLPHADGRYYLGESLDALSFNNDGNGNAVMTMHDRLMGDNSGTREPTGDN
>Mature_457_residues
MKTIAMMLLATALSMAGTARATGTTPPASATAELAREAAAFFKDSQPGGVVLVTRGDQVLLRRAYGMADIENGVAMQPDA
AMRLASVSKQFTAMAVLQLVQAGKLQLDTCLESVDPALSGPLAKVTVQQLLTHTSGIKNVSSIAASRAARREDTDARSLM
NYFKDLPLEFAAGTRFRYSNSNYIVLTYLIERITAQPYPVYMQQSLFQPLGMLHTRYDDHLTVIAQRAHGYRRAQGQLQN
ADFISMSQPQGAGGLISTVDDLAIWHRALRDGLPVSASLLAQAMRKTTLADGSASPYGFGWIIGQVNGMADVEHGGFING
FNSYVMRVTQPDVFVTVLTNAEFLDPTNLSVRLAAIAAGHAYAATVALRSQDRAWLGRYRFAADDVRVLAEVDGALQLQR
EGEDPVAVLPHADGRYYLGESLDALSFNNDGNGNAVMTMHDRLMGDNSGTREPTGDN

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082101, Length=302, Percent_Identity=25.1655629139073, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533026, Length=334, Percent_Identity=24.8502994011976, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17550934, Length=191, Percent_Identity=28.7958115183246, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 49312; Mature: 49312

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIAMMLLATALSMAGTARATGTTPPASATAELAREAAAFFKDSQPGGVVLVTRGDQVL
CHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHH
LRRAYGMADIENGVAMQPDAAMRLASVSKQFTAMAVLQLVQAGKLQLDTCLESVDPALSG
HHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHCC
PLAKVTVQQLLTHTSGIKNVSSIAASRAARREDTDARSLMNYFKDLPLEFAAGTRFRYSN
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECC
SNYIVLTYLIERITAQPYPVYMQQSLFQPLGMLHTRYDDHLTVIAQRAHGYRRAQGQLQN
CCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHCCCCCC
ADFISMSQPQGAGGLISTVDDLAIWHRALRDGLPVSASLLAQAMRKTTLADGSASPYGFG
CCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEE
WIIGQVNGMADVEHGGFINGFNSYVMRVTQPDVFVTVLTNAEFLDPTNLSVRLAAIAAGH
EEEEECCCCEECCCCCEECCCCCEEEEEECCCEEEEEECCCCCCCCCCCEEEEEEEECCC
AYAATVALRSQDRAWLGRYRFAADDVRVLAEVDGALQLQREGEDPVAVLPHADGRYYLGE
HHEEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCEECCC
SLDALSFNNDGNGNAVMTMHDRLMGDNSGTREPTGDN
CCCEEECCCCCCCCEEEEEEHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKTIAMMLLATALSMAGTARATGTTPPASATAELAREAAAFFKDSQPGGVVLVTRGDQVL
CHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHH
LRRAYGMADIENGVAMQPDAAMRLASVSKQFTAMAVLQLVQAGKLQLDTCLESVDPALSG
HHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHCC
PLAKVTVQQLLTHTSGIKNVSSIAASRAARREDTDARSLMNYFKDLPLEFAAGTRFRYSN
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECC
SNYIVLTYLIERITAQPYPVYMQQSLFQPLGMLHTRYDDHLTVIAQRAHGYRRAQGQLQN
CCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHCCCCCC
ADFISMSQPQGAGGLISTVDDLAIWHRALRDGLPVSASLLAQAMRKTTLADGSASPYGFG
CCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEE
WIIGQVNGMADVEHGGFINGFNSYVMRVTQPDVFVTVLTNAEFLDPTNLSVRLAAIAAGH
EEEEECCCCEECCCCCEECCCCCEEEEEECCCEEEEEECCCCCCCCCCCEEEEEEEECCC
AYAATVALRSQDRAWLGRYRFAADDVRVLAEVDGALQLQREGEDPVAVLPHADGRYYLGE
HHEEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCEECCC
SLDALSFNNDGNGNAVMTMHDRLMGDNSGTREPTGDN
CCCEEECCCCCCCCEEEEEEHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA