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The map label for this gene is mcp4 [H]

Identifier: 78047600

GI number: 78047600

Start: 2328184

End: 2329374

Strand: Reverse

Name: mcp4 [H]

Synonym: XCV2044

Alternate gene names: 78047600

Gene position: 2329374-2328184 (Counterclockwise)

Preceding gene: 78047601

Following gene: 78047599

Centisome position: 44.98

GC content: 64.57

Gene sequence:

>1191_bases
ATGTATTCACGTCCACTCATCCGTCTAGCCGCTCCTTTGGCTCTGACCTTGCTGTTCCCCTTCGCTGTCGGATTCGACTG
GCCCGCTTCGGTGCGCTGGGCGATCCTGGCGACCATGACCCTCAGTTGGTTGGGTTTCGCTGCCTGGGTGACGTATTCCC
AGTTCCGGCCTAATCCGGACCAGGCCCGCATCCTGCGCGAGCAGGACCAACTGCTCAACGAACTGCGCACGTTCGTCAGC
AACGAAGTCGACGGTTCGCGCTCGGAAGTCGAGCGTGCCCGCGAACTGATCCGCCAGGCCGTGTCCGGCCTGGGTGGCAG
CTTCGAAGCGATGAATCGCAAATCGCGTCAGCAAAGCCAGGCACTGGCCCGCATCGTCGACCGTGCCGGTGACGATGGCA
GCGCCGGCGTCGACGTCGCCCGCTTCGCCCAGCACGCCAGCTCCCGCATGGAGCAGTTGGTGGAAGCGCTGGAACAGGTG
AGCGGCCAAAGTACCAATACCGTCCATCACATCGACGAGATGGCGCAGCATCTGGATGGCATCTTCGCGCTGCTGGAAGA
CGTCAAGTCGATTGCCGACCAGACCAACCTGCTGGCCTTGAACGCCGCCATCGAAGCAGCGCGTGCCGGTGAAGCCGGTC
GCGGCTTCGCCGTGGTTGCCGACGAGGTGCGCAACCTGTCCGAGCGTTCCACCACCTTCAACGAGCAGATCCGCAAGCTG
GCACACAGCTCCAAGGAATCGATCGCCAAGGTGCGTGAAACGGTCTCGCAGCTGGCCTCGCGCCACATGGACCGCTCCCG
CGAGGCGCGCCATGAATCGGCCGCCATGCTGGAGAACGTCGCCCAGATCAACGCCTCGTTGGGCGATGGCATGCGCGAGA
TCTCCGAATGCGCACGCTCGATCGATGGCAGCGTGGCCGAAGCGGTGCGTGCCCTGCAGTTCGAGGACATCGCCACGCAG
ACGCTGAGCGGTATCCACACCCACCTGGATCGCCTGACCGCGATCAACCGCGAAGCGGTGGCGCTGCAGGAACTGCTGCA
TCGCAATGGCGGCGTATACGACAGCGATCTGGTCGCCGCGCTGGCCAAGGTGTCCAACCGCCTGCGCGACATGCGCGTGG
AGTGGGAGCGCCCGCCGCACAAGCCGGTGGCGCAGCAAGGCATGGGTGCCGGCACGGTCGAGTTGTTCTAA

Upstream 100 bases:

>100_bases
GCGCCAACGGCGGTTGAATGGGCCAGGCGATGTGGCGATCGTCGCTAAAGACAACGGGGGCAGTGCCGATACAGCAACCG
TGACTCTGCCGAGAACGCCC

Downstream 100 bases:

>100_bases
GACCGATGCCGCCACGCAGCTGCTGATTCCGACATTCCCCGGCCTTCCGGGGATTTGTCGTTCCGTTACGACCTGGTGTT
CCGCCCATGACGCTTGTTGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MYSRPLIRLAAPLALTLLFPFAVGFDWPASVRWAILATMTLSWLGFAAWVTYSQFRPNPDQARILREQDQLLNELRTFVS
NEVDGSRSEVERARELIRQAVSGLGGSFEAMNRKSRQQSQALARIVDRAGDDGSAGVDVARFAQHASSRMEQLVEALEQV
SGQSTNTVHHIDEMAQHLDGIFALLEDVKSIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLSERSTTFNEQIRKL
AHSSKESIAKVRETVSQLASRHMDRSREARHESAAMLENVAQINASLGDGMREISECARSIDGSVAEAVRALQFEDIATQ
TLSGIHTHLDRLTAINREAVALQELLHRNGGVYDSDLVAALAKVSNRLRDMRVEWERPPHKPVAQQGMGAGTVELF

Sequences:

>Translated_396_residues
MYSRPLIRLAAPLALTLLFPFAVGFDWPASVRWAILATMTLSWLGFAAWVTYSQFRPNPDQARILREQDQLLNELRTFVS
NEVDGSRSEVERARELIRQAVSGLGGSFEAMNRKSRQQSQALARIVDRAGDDGSAGVDVARFAQHASSRMEQLVEALEQV
SGQSTNTVHHIDEMAQHLDGIFALLEDVKSIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLSERSTTFNEQIRKL
AHSSKESIAKVRETVSQLASRHMDRSREARHESAAMLENVAQINASLGDGMREISECARSIDGSVAEAVRALQFEDIATQ
TLSGIHTHLDRLTAINREAVALQELLHRNGGVYDSDLVAALAKVSNRLRDMRVEWERPPHKPVAQQGMGAGTVELF
>Mature_396_residues
MYSRPLIRLAAPLALTLLFPFAVGFDWPASVRWAILATMTLSWLGFAAWVTYSQFRPNPDQARILREQDQLLNELRTFVS
NEVDGSRSEVERARELIRQAVSGLGGSFEAMNRKSRQQSQALARIVDRAGDDGSAGVDVARFAQHASSRMEQLVEALEQV
SGQSTNTVHHIDEMAQHLDGIFALLEDVKSIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLSERSTTFNEQIRKL
AHSSKESIAKVRETVSQLASRHMDRSREARHESAAMLENVAQINASLGDGMREISECARSIDGSVAEAVRALQFEDIATQ
TLSGIHTHLDRLTAINREAVALQELLHRNGGVYDSDLVAALAKVSNRLRDMRVEWERPPHKPVAQQGMGAGTVELF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=241, Percent_Identity=31.5352697095436, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788194, Length=183, Percent_Identity=30.0546448087432, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788195, Length=122, Percent_Identity=40.1639344262295, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367378, Length=86, Percent_Identity=47.6744186046512, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787690, Length=214, Percent_Identity=30.8411214953271, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 43629; Mature: 43629

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSRPLIRLAAPLALTLLFPFAVGFDWPASVRWAILATMTLSWLGFAAWVTYSQFRPNPD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
QARILREQDQLLNELRTFVSNEVDGSRSEVERARELIRQAVSGLGGSFEAMNRKSRQQSQ
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ALARIVDRAGDDGSAGVDVARFAQHASSRMEQLVEALEQVSGQSTNTVHHIDEMAQHLDG
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IFALLEDVKSIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLSERSTTFNEQIRKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AHSSKESIAKVRETVSQLASRHMDRSREARHESAAMLENVAQINASLGDGMREISECARS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDGSVAEAVRALQFEDIATQTLSGIHTHLDRLTAINREAVALQELLHRNGGVYDSDLVAA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LAKVSNRLRDMRVEWERPPHKPVAQQGMGAGTVELF
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MYSRPLIRLAAPLALTLLFPFAVGFDWPASVRWAILATMTLSWLGFAAWVTYSQFRPNPD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
QARILREQDQLLNELRTFVSNEVDGSRSEVERARELIRQAVSGLGGSFEAMNRKSRQQSQ
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ALARIVDRAGDDGSAGVDVARFAQHASSRMEQLVEALEQVSGQSTNTVHHIDEMAQHLDG
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IFALLEDVKSIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLSERSTTFNEQIRKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AHSSKESIAKVRETVSQLASRHMDRSREARHESAAMLENVAQINASLGDGMREISECARS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDGSVAEAVRALQFEDIATQTLSGIHTHLDRLTAINREAVALQELLHRNGGVYDSDLVAA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LAKVSNRLRDMRVEWERPPHKPVAQQGMGAGTVELF
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]