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The map label for this gene is cheA2 [H]

Identifier: 78047530

GI number: 78047530

Start: 2248718

End: 2250376

Strand: Reverse

Name: cheA2 [H]

Synonym: XCV1974

Alternate gene names: 78047530

Gene position: 2250376-2248718 (Counterclockwise)

Preceding gene: 78047531

Following gene: 78047518

Centisome position: 43.46

GC content: 68.29

Gene sequence:

>1659_bases
ATGAGTGCTGTTCCAGACGATATTGCTGCCGATTTCATCGTCGAGGCCCAGGAAATCCTGGATCGCCTCGGCGAACAGCT
GGTCTCGCTGGAACAGGCGCCAGAAGAAGCCGACCAGCTCAACGCGGTGTTCCGCGGCTTCCACACGCTCAAGGGCGGCG
CCGGCTTTCTGGCGATCAAGCCCATGGTGGAGCTGTGCCACGCCGCTGAAGAAACCTTGGGCATGGCGCGCTCGGGCCAG
GCGGTGCTGCAGGCGCATCACTTCGATGCCGCGCAACAATCGCTGGATTATCTGCAGGCCATGCTGGATGCCATGGGCTC
GGGCGAAGCCGTGCCGCACGCACCGGCCACGTTGATCGCGCAGTTCGACGCCAAGAGCGCCCCGCCGGCGGTCAAGGCCG
CGCCGCAGGCGGCCGCGGCCAAGCCGGTTGCCGCCGCACACGGCGACGATGCGCATGCGCCCGCCCCCAAGGCGGCCGGC
AAGGGCGCGGCCAAGACCGGCGCCGAAGCCGAACAGACCGTGCGCGTGGACACCAAGCGCCTGGACGCCATCGTCAACCT
GATCGGCGAACTTGTGCTCTCGCGCAACCGGCTGAAGACCTTGCGCACCCGCCTGCGCGACGAAGAACTGGACCGCGCGG
TCAGCACGCTCGACATCGCCACCGCACGCCTGCAGACCGCGGTGATGCGTACCCGCATGCAGCCGGTCAGCAAGGTGTTC
GCACGCTTCCCCAAGGTGGCCCGCGATGTCGCGCGCACGCTGTCCAAGGAAGTGGAACTGGAACTGATCGGCGCCGAGAC
GGAACTGGACCGCAACCTGGTCGAGGCCCTGGCCGACCCGCTGGTGCACCTGGTGCGCAACGCAATCGACCACGGCATCG
AATCGCCGGCCCTGCGCGAAGCCACCGGCAAACCGCGCAGCGGCCATGTGCGCCTGTCGGCGCAGCAGGAAGGCGACTAC
GTCAGCATCGAAATCCAGGACGACGGCGCCGGCATCGACCCGGAGCGCCTGCGCGAAATCGCCCGCAACAAGGGCCTGAT
CGACGCCGAAGCCGCCGCGCGCCTGAGCACCGACGAGTGCTTGCATCTGATCTTCATGCCGGGCTTCTCGACCAAGGTGG
AAGTCACCGACATCTCCGGCCGTGGCGTGGGCATGGACGTGGTGCAGTCGCGTATCCGCGAACTCAGCGGGCAGATCCAG
ATCCAGTCCGAACTGGGCCGCGGCAGCCGCTTCATGATCCGCGTGCCGTTGACCCTGGCGATTCTGCCGACCCTGCTGGT
GCAGGCCGGCGAAGCGGTCTACGCATTGCCGCTGGCGCGCGTGGTGGAAGTGCTGCATGCACCGCAAACCTCGCTGGGCT
GGTTCGACGGCCGCGCCGTGCTGGACCGCCGCTCGCACACCCTGCCGCTGATCGACCTGCGCCGCTGGCTGGGCGTACCG
GCCGAACAGCCGCCGCTACTGACCGTGGTGCTGCTGCAGGCCGGCGAAACCCGCTTCGGCCTGGTGGTAGACCAGGTCCG
CGGCCGCGAGGAAGTGGTGATCAAGCCCCTGCCCCGTGCCCTGCGCGGCCTGCCCGGCTACGCCGGCGCCACCCTGATCG
GCGATGGCCGCATGGCGCTGATCCTGGATGTGGATGGGCTGCGTTCCAGCGATCATTGA

Upstream 100 bases:

>100_bases
ACGACGGCGGTCTTGCCGGTCCTGCAGTCAAGGGCCTGGACCGTCACGCGGTGTCGCAGGACGATGCCGACGACCTGCTG
TCCGGATTGGGGCTGTAACC

Downstream 100 bases:

>100_bases
GGTTGGGGATTCGGGATTCGGGATTGGGAGAATCGGGAATCGGGAATCGGGAATCGGGAAGACGATCCTGTTTGCCTGAT
CTAACGACAACGGCCGCGTA

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MSAVPDDIAADFIVEAQEILDRLGEQLVSLEQAPEEADQLNAVFRGFHTLKGGAGFLAIKPMVELCHAAEETLGMARSGQ
AVLQAHHFDAAQQSLDYLQAMLDAMGSGEAVPHAPATLIAQFDAKSAPPAVKAAPQAAAAKPVAAAHGDDAHAPAPKAAG
KGAAKTGAEAEQTVRVDTKRLDAIVNLIGELVLSRNRLKTLRTRLRDEELDRAVSTLDIATARLQTAVMRTRMQPVSKVF
ARFPKVARDVARTLSKEVELELIGAETELDRNLVEALADPLVHLVRNAIDHGIESPALREATGKPRSGHVRLSAQQEGDY
VSIEIQDDGAGIDPERLREIARNKGLIDAEAAARLSTDECLHLIFMPGFSTKVEVTDISGRGVGMDVVQSRIRELSGQIQ
IQSELGRGSRFMIRVPLTLAILPTLLVQAGEAVYALPLARVVEVLHAPQTSLGWFDGRAVLDRRSHTLPLIDLRRWLGVP
AEQPPLLTVVLLQAGETRFGLVVDQVRGREEVVIKPLPRALRGLPGYAGATLIGDGRMALILDVDGLRSSDH

Sequences:

>Translated_552_residues
MSAVPDDIAADFIVEAQEILDRLGEQLVSLEQAPEEADQLNAVFRGFHTLKGGAGFLAIKPMVELCHAAEETLGMARSGQ
AVLQAHHFDAAQQSLDYLQAMLDAMGSGEAVPHAPATLIAQFDAKSAPPAVKAAPQAAAAKPVAAAHGDDAHAPAPKAAG
KGAAKTGAEAEQTVRVDTKRLDAIVNLIGELVLSRNRLKTLRTRLRDEELDRAVSTLDIATARLQTAVMRTRMQPVSKVF
ARFPKVARDVARTLSKEVELELIGAETELDRNLVEALADPLVHLVRNAIDHGIESPALREATGKPRSGHVRLSAQQEGDY
VSIEIQDDGAGIDPERLREIARNKGLIDAEAAARLSTDECLHLIFMPGFSTKVEVTDISGRGVGMDVVQSRIRELSGQIQ
IQSELGRGSRFMIRVPLTLAILPTLLVQAGEAVYALPLARVVEVLHAPQTSLGWFDGRAVLDRRSHTLPLIDLRRWLGVP
AEQPPLLTVVLLQAGETRFGLVVDQVRGREEVVIKPLPRALRGLPGYAGATLIGDGRMALILDVDGLRSSDH
>Mature_551_residues
SAVPDDIAADFIVEAQEILDRLGEQLVSLEQAPEEADQLNAVFRGFHTLKGGAGFLAIKPMVELCHAAEETLGMARSGQA
VLQAHHFDAAQQSLDYLQAMLDAMGSGEAVPHAPATLIAQFDAKSAPPAVKAAPQAAAAKPVAAAHGDDAHAPAPKAAGK
GAAKTGAEAEQTVRVDTKRLDAIVNLIGELVLSRNRLKTLRTRLRDEELDRAVSTLDIATARLQTAVMRTRMQPVSKVFA
RFPKVARDVARTLSKEVELELIGAETELDRNLVEALADPLVHLVRNAIDHGIESPALREATGKPRSGHVRLSAQQEGDYV
SIEIQDDGAGIDPERLREIARNKGLIDAEAAARLSTDECLHLIFMPGFSTKVEVTDISGRGVGMDVVQSRIRELSGQIQI
QSELGRGSRFMIRVPLTLAILPTLLVQAGEAVYALPLARVVEVLHAPQTSLGWFDGRAVLDRRSHTLPLIDLRRWLGVPA
EQPPLLTVVLLQAGETRFGLVVDQVRGREEVVIKPLPRALRGLPGYAGATLIGDGRMALILDVDGLRSSDH

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=407, Percent_Identity=41.2776412776413, Blast_Score=292, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59387; Mature: 59256

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPDDIAADFIVEAQEILDRLGEQLVSLEQAPEEADQLNAVFRGFHTLKGGAGFLAIK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEHHH
PMVELCHAAEETLGMARSGQAVLQAHHFDAAQQSLDYLQAMLDAMGSGEAVPHAPATLIA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHE
QFDAKSAPPAVKAAPQAAAAKPVAAAHGDDAHAPAPKAAGKGAAKTGAEAEQTVRVDTKR
ECCCCCCCCCHHCCCCHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LDAIVNLIGELVLSRNRLKTLRTRLRDEELDRAVSTLDIATARLQTAVMRTRMQPVSKVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARFPKVARDVARTLSKEVELELIGAETELDRNLVEALADPLVHLVRNAIDHGIESPALRE
HHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ATGKPRSGHVRLSAQQEGDYVSIEIQDDGAGIDPERLREIARNKGLIDAEAAARLSTDEC
HCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHCCHHHH
LHLIFMPGFSTKVEVTDISGRGVGMDVVQSRIRELSGQIQIQSELGRGSRFMIRVPLTLA
EEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEHHCCCCCEEEEECCHHHH
ILPTLLVQAGEAVYALPLARVVEVLHAPQTSLGWFDGRAVLDRRSHTLPLIDLRRWLGVP
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCC
AEQPPLLTVVLLQAGETRFGLVVDQVRGREEVVIKPLPRALRGLPGYAGATLIGDGRMAL
CCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEECCCHHHHHCCCCCCCCEEECCCCEEE
ILDVDGLRSSDH
EEEECCCCCCCC
>Mature Secondary Structure 
SAVPDDIAADFIVEAQEILDRLGEQLVSLEQAPEEADQLNAVFRGFHTLKGGAGFLAIK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEHHH
PMVELCHAAEETLGMARSGQAVLQAHHFDAAQQSLDYLQAMLDAMGSGEAVPHAPATLIA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHE
QFDAKSAPPAVKAAPQAAAAKPVAAAHGDDAHAPAPKAAGKGAAKTGAEAEQTVRVDTKR
ECCCCCCCCCHHCCCCHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LDAIVNLIGELVLSRNRLKTLRTRLRDEELDRAVSTLDIATARLQTAVMRTRMQPVSKVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARFPKVARDVARTLSKEVELELIGAETELDRNLVEALADPLVHLVRNAIDHGIESPALRE
HHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ATGKPRSGHVRLSAQQEGDYVSIEIQDDGAGIDPERLREIARNKGLIDAEAAARLSTDEC
HCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHCCHHHH
LHLIFMPGFSTKVEVTDISGRGVGMDVVQSRIRELSGQIQIQSELGRGSRFMIRVPLTLA
EEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEHHCCCCCEEEEECCHHHH
ILPTLLVQAGEAVYALPLARVVEVLHAPQTSLGWFDGRAVLDRRSHTLPLIDLRRWLGVP
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCC
AEQPPLLTVVLLQAGETRFGLVVDQVRGREEVVIKPLPRALRGLPGYAGATLIGDGRMAL
CCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEECCCHHHHHCCCCCCCCEEECCCCEEE
ILDVDGLRSSDH
EEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]