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The map label for this gene is tsr [H]

Identifier: 78047508

GI number: 78047508

Start: 2221310

End: 2223487

Strand: Reverse

Name: tsr [H]

Synonym: XCV1952

Alternate gene names: 78047508

Gene position: 2223487-2221310 (Counterclockwise)

Preceding gene: 78047509

Following gene: 78047507

Centisome position: 42.94

GC content: 64.55

Gene sequence:

>2178_bases
ATGACGCTGAAGACCACGGTTGCAAAAACACTGGCCAATGTACCGCTCAAGCGCAGGTTCTTCGCCCAGACTGCCCTGGT
TGCGCTGGGCATCATTGCGTTGGCGGTGATCGCCGCACGCATGCAGTACGTCGATCTGACCGATACGCGCCGCGATGGGC
TCAAGAGCCAGATCGAGATGGCGACTGCGGTGGTCAATGGCTATGCCGAACGCGCCGAAAAGGGCGAGATCGACGTGGAG
ACCGCCAAAAAGAGTGCGCTGCATACTCTGTCGACCATGCGTGCACGTGGCGGTGTGGATTACATCTACGTCACCGACCA
GACGCCGACGATGCTGATGCACCCCACCCGCCCGGACCTGGTCGGCAAGCCGTTGAGCGACGTGCTCAGCCCGGACGGCA
AGCGCGTGTTTCCAGCATTCGTCACCGCAGCGCAGGCCGGCGGCGGCTATGTCGACTACACCTGGGCCAAGCCAGGGCAG
AAGGATCCGGTGCAGAAAACCTCGTACGCGGCGCTGTACAAGCCGTGGGGCTGGGTGATCGGCACCGGCGTGTACCTGGA
CGACACCCAATCGCAGGCGCTGGTTTTCACCGGCATCGTTGCGCTCGCCGGTGGCGCCCTGGTGCTGATCAACCTGCTGG
TGGGCTGGCTGATCGGCAATTCCATCCTGGAGCCGGTGTCGCGTGCCCTGGCGGCCATCAAGGGCGTGGCGCGCGGCGAC
CTGAGCGTGCGTACTGCCGAACACGGCACCGATGAAATCGGCCAGATGCTCAAGGCCACCGACGAGATGGTCCACACCTT
GGAGCGCTTCTCCGCGCAGACCAAGGTGATGGTGCACATGCATGCCGGCGACGATGTCACCCACCGCATGCCGACCAATT
TCCCGGGCGTCTACGGCGAACTGGCCACCGGCATCAACACGATGATCTTCGAGCACCTGGATGCCATCGTCGATGCGATC
GGCATCCTCAACGAGTATGCGCAAGGCGACCTGTCGCGCAATGCCGCGCGCCTGCCCGGCACGCGTGCGGTGCTGCACGA
AGCGATGGACGCGGCCAAGGCCAGCCTGCTGGCGATCAACACCGAGATCAAGCGACTGGCGCAAGCTGCAGCCAACGGCG
ACTTCAGTCAACGCGGCGATGCCACGCGCTTCAAGCACGACTCGGCGCGCATGATCAACGACCTCAACGCGATGATGGAG
GTCAGCGACCGCAACCTGGGCAAGCTGTCCGAGCTGCTGGCATCCCTGGCCGAAGGCGACCTCACTGCGCGCCTGGATGG
CCAGTACCATGGCGTGTTCGCGCGCATGCGCGACGACGCCAACACCACGGCCACCCAACTGGCCGGCATCGTCGGGCGCA
TCCAGCAGGCCGCCAGTTCCATCACCGGCTCGGCCAGCGAAATCGCCGCAGGCAACAACGATCTGTCCCAGCGCACCGAA
CAGCAGGCCGCCAATCTGGAAGAAACCGCCGCCTCGATGGAGGAGCTCACTTCCACCGTCAAGCAGAATGCCGAAAGCGC
ACGCCAGGCCAACCAGTTGGCGATCGGCGCCGCCAGCGTGGCCTCGCAGGGCGGCCAGGTGGTGAGCCAGGTGGTGGACA
CCATGTCCGGTATCCAGACCTCGTCCAAGAAGATCGCCGAGATCATCAGCGTCATCGACGGCATCGCCTTCCAGACCAAT
ATCCTGGCACTGAATGCCGCGGTGGAAGCCGCACGTGCCGGCGAACAAGGCCGCGGATTTGCGGTGGTCGCCTCGGAAGT
ACGCACGCTGGCCCAGCGTTCGGCCAATGCGGCCAAAGAGATCAAGCACCTCATCGACGATTCGGTGGGCAAGGTGTCCG
AGGGCTCGCTGCTGGTGGATCAGGCCGGCAAGACCATGGCCGAGATCGTCTCTTCGGTGCAGCGCGTCACCGACATCATG
AGCGAAATTTCTGCCGCCTCGCAGGAACAGTCGGCCGGGATCGAACAGGTCAACCTCACCGTCACCCAGATGGACGAGAG
CACGCAGCAGAACGCGGCGCTGGTGGAAGAAGCCACCGCAGCGGCCAATGCCATGCAGCAGCAGGCGCAGCAGCTGGATG
AGGCGGTGTCCAGCTTCCGGATCGTCGCTGCCACCTCCAAGACGTTCGGCCATGCCGGCACACGCGCGCCGGCGCGGGTT
GCGCTGGCCACCTACTGA

Upstream 100 bases:

>100_bases
CACGAATCGGCCGCCACCTGCGTTGTGTCCGGCTCAACATTTTCGGAATCAGGTCGCTATTCGACTTACACCGGTCACAT
TCCTTTGCTGGATATCTGCC

Downstream 100 bases:

>100_bases
CCGCACATGCCCCGCTTCGGCCGGGTTGTCTTCTCCCTTTTCCTTTTTCCTTCCGCGGCTACGCCCATGACCTCGCCTTC
CACCCACTCACGTTTCAGCG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 725; Mature: 724

Protein sequence:

>725_residues
MTLKTTVAKTLANVPLKRRFFAQTALVALGIIALAVIAARMQYVDLTDTRRDGLKSQIEMATAVVNGYAERAEKGEIDVE
TAKKSALHTLSTMRARGGVDYIYVTDQTPTMLMHPTRPDLVGKPLSDVLSPDGKRVFPAFVTAAQAGGGYVDYTWAKPGQ
KDPVQKTSYAALYKPWGWVIGTGVYLDDTQSQALVFTGIVALAGGALVLINLLVGWLIGNSILEPVSRALAAIKGVARGD
LSVRTAEHGTDEIGQMLKATDEMVHTLERFSAQTKVMVHMHAGDDVTHRMPTNFPGVYGELATGINTMIFEHLDAIVDAI
GILNEYAQGDLSRNAARLPGTRAVLHEAMDAAKASLLAINTEIKRLAQAAANGDFSQRGDATRFKHDSARMINDLNAMME
VSDRNLGKLSELLASLAEGDLTARLDGQYHGVFARMRDDANTTATQLAGIVGRIQQAASSITGSASEIAAGNNDLSQRTE
QQAANLEETAASMEELTSTVKQNAESARQANQLAIGAASVASQGGQVVSQVVDTMSGIQTSSKKIAEIISVIDGIAFQTN
ILALNAAVEAARAGEQGRGFAVVASEVRTLAQRSANAAKEIKHLIDDSVGKVSEGSLLVDQAGKTMAEIVSSVQRVTDIM
SEISAASQEQSAGIEQVNLTVTQMDESTQQNAALVEEATAAANAMQQQAQQLDEAVSSFRIVAATSKTFGHAGTRAPARV
ALATY

Sequences:

>Translated_725_residues
MTLKTTVAKTLANVPLKRRFFAQTALVALGIIALAVIAARMQYVDLTDTRRDGLKSQIEMATAVVNGYAERAEKGEIDVE
TAKKSALHTLSTMRARGGVDYIYVTDQTPTMLMHPTRPDLVGKPLSDVLSPDGKRVFPAFVTAAQAGGGYVDYTWAKPGQ
KDPVQKTSYAALYKPWGWVIGTGVYLDDTQSQALVFTGIVALAGGALVLINLLVGWLIGNSILEPVSRALAAIKGVARGD
LSVRTAEHGTDEIGQMLKATDEMVHTLERFSAQTKVMVHMHAGDDVTHRMPTNFPGVYGELATGINTMIFEHLDAIVDAI
GILNEYAQGDLSRNAARLPGTRAVLHEAMDAAKASLLAINTEIKRLAQAAANGDFSQRGDATRFKHDSARMINDLNAMME
VSDRNLGKLSELLASLAEGDLTARLDGQYHGVFARMRDDANTTATQLAGIVGRIQQAASSITGSASEIAAGNNDLSQRTE
QQAANLEETAASMEELTSTVKQNAESARQANQLAIGAASVASQGGQVVSQVVDTMSGIQTSSKKIAEIISVIDGIAFQTN
ILALNAAVEAARAGEQGRGFAVVASEVRTLAQRSANAAKEIKHLIDDSVGKVSEGSLLVDQAGKTMAEIVSSVQRVTDIM
SEISAASQEQSAGIEQVNLTVTQMDESTQQNAALVEEATAAANAMQQQAQQLDEAVSSFRIVAATSKTFGHAGTRAPARV
ALATY
>Mature_724_residues
TLKTTVAKTLANVPLKRRFFAQTALVALGIIALAVIAARMQYVDLTDTRRDGLKSQIEMATAVVNGYAERAEKGEIDVET
AKKSALHTLSTMRARGGVDYIYVTDQTPTMLMHPTRPDLVGKPLSDVLSPDGKRVFPAFVTAAQAGGGYVDYTWAKPGQK
DPVQKTSYAALYKPWGWVIGTGVYLDDTQSQALVFTGIVALAGGALVLINLLVGWLIGNSILEPVSRALAAIKGVARGDL
SVRTAEHGTDEIGQMLKATDEMVHTLERFSAQTKVMVHMHAGDDVTHRMPTNFPGVYGELATGINTMIFEHLDAIVDAIG
ILNEYAQGDLSRNAARLPGTRAVLHEAMDAAKASLLAINTEIKRLAQAAANGDFSQRGDATRFKHDSARMINDLNAMMEV
SDRNLGKLSELLASLAEGDLTARLDGQYHGVFARMRDDANTTATQLAGIVGRIQQAASSITGSASEIAAGNNDLSQRTEQ
QAANLEETAASMEELTSTVKQNAESARQANQLAIGAASVASQGGQVVSQVVDTMSGIQTSSKKIAEIISVIDGIAFQTNI
LALNAAVEAARAGEQGRGFAVVASEVRTLAQRSANAAKEIKHLIDDSVGKVSEGSLLVDQAGKTMAEIVSSVQRVTDIMS
EISAASQEQSAGIEQVNLTVTQMDESTQQNAALVEEATAAANAMQQQAQQLDEAVSSFRIVAATSKTFGHAGTRAPARVA
LATY

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=313, Percent_Identity=60.702875399361, Blast_Score=309, Evalue=5e-85,
Organism=Escherichia coli, GI1788195, Length=258, Percent_Identity=65.5038759689922, Blast_Score=292, Evalue=5e-80,
Organism=Escherichia coli, GI1787690, Length=298, Percent_Identity=57.0469798657718, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI1788194, Length=295, Percent_Identity=56.271186440678, Blast_Score=280, Evalue=3e-76,
Organism=Escherichia coli, GI1789453, Length=248, Percent_Identity=44.3548387096774, Blast_Score=206, Evalue=6e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 76853; Mature: 76722

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKTTVAKTLANVPLKRRFFAQTALVALGIIALAVIAARMQYVDLTDTRRDGLKSQIEM
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ATAVVNGYAERAEKGEIDVETAKKSALHTLSTMRARGGVDYIYVTDQTPTMLMHPTRPDL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCC
VGKPLSDVLSPDGKRVFPAFVTAAQAGGGYVDYTWAKPGQKDPVQKTSYAALYKPWGWVI
CCCCHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCEE
GTGVYLDDTQSQALVFTGIVALAGGALVLINLLVGWLIGNSILEPVSRALAAIKGVARGD
ECCEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSVRTAEHGTDEIGQMLKATDEMVHTLERFSAQTKVMVHMHAGDDVTHRMPTNFPGVYGE
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHH
LATGINTMIFEHLDAIVDAIGILNEYAQGDLSRNAARLPGTRAVLHEAMDAAKASLLAIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
TEIKRLAQAAANGDFSQRGDATRFKHDSARMINDLNAMMEVSDRNLGKLSELLASLAEGD
HHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
LTARLDGQYHGVFARMRDDANTTATQLAGIVGRIQQAASSITGSASEIAAGNNDLSQRTE
CEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHH
QQAANLEETAASMEELTSTVKQNAESARQANQLAIGAASVASQGGQVVSQVVDTMSGIQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
SSKKIAEIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLAQRSANAAKE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHH
IKHLIDDSVGKVSEGSLLVDQAGKTMAEIVSSVQRVTDIMSEISAASQEQSAGIEQVNLT
HHHHHHHHCCCCCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VTQMDESTQQNAALVEEATAAANAMQQQAQQLDEAVSSFRIVAATSKTFGHAGTRAPARV
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHCCCCCCCCCCE
ALATY
EEECC
>Mature Secondary Structure 
TLKTTVAKTLANVPLKRRFFAQTALVALGIIALAVIAARMQYVDLTDTRRDGLKSQIEM
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ATAVVNGYAERAEKGEIDVETAKKSALHTLSTMRARGGVDYIYVTDQTPTMLMHPTRPDL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCC
VGKPLSDVLSPDGKRVFPAFVTAAQAGGGYVDYTWAKPGQKDPVQKTSYAALYKPWGWVI
CCCCHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCEE
GTGVYLDDTQSQALVFTGIVALAGGALVLINLLVGWLIGNSILEPVSRALAAIKGVARGD
ECCEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSVRTAEHGTDEIGQMLKATDEMVHTLERFSAQTKVMVHMHAGDDVTHRMPTNFPGVYGE
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHH
LATGINTMIFEHLDAIVDAIGILNEYAQGDLSRNAARLPGTRAVLHEAMDAAKASLLAIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
TEIKRLAQAAANGDFSQRGDATRFKHDSARMINDLNAMMEVSDRNLGKLSELLASLAEGD
HHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
LTARLDGQYHGVFARMRDDANTTATQLAGIVGRIQQAASSITGSASEIAAGNNDLSQRTE
CEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHH
QQAANLEETAASMEELTSTVKQNAESARQANQLAIGAASVASQGGQVVSQVVDTMSGIQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
SSKKIAEIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLAQRSANAAKE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHH
IKHLIDDSVGKVSEGSLLVDQAGKTMAEIVSSVQRVTDIMSEISAASQEQSAGIEQVNLT
HHHHHHHHCCCCCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VTQMDESTQQNAALVEEATAAANAMQQQAQQLDEAVSSFRIVAATSKTFGHAGTRAPARV
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHCCCCCCCCCCE
ALATY
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]