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The map label for this gene is mtnC [H]

Identifier: 78047440

GI number: 78047440

Start: 2131320

End: 2132018

Strand: Reverse

Name: mtnC [H]

Synonym: XCV1884

Alternate gene names: 78047440

Gene position: 2132018-2131320 (Counterclockwise)

Preceding gene: 78047441

Following gene: 78047439

Centisome position: 41.17

GC content: 63.38

Gene sequence:

>699_bases
ATGACACGACCGCAAGCGATCCTCACCGATATCGAAGGTACGACCAGCAGCATTTCGTTCGTCAAGGACGTCTTGTTCCC
GTATGCGCGCCGCGCCATGCCGGCCTACGTGCGCGAACACGGCAATCATCCGCAGGTGCGCCATTGGCTCAACCAGGTGG
CCGATGAAATCGGCGAGGACGTGCCGGACGAGGTGCTGATCACCACGCTGCAGACCTGGATCGACGAGGACCGCAAGCAC
ACCGCGCTCAAGGCCTTGCAGGGCCTGATCTGGGGCGACGGCTACAAGACGGCCGACTTCACTGCACATATCTACGCCGA
TGCGGCGATCCAGTTGAAAGCCTGGCACGCAGCGGGCATTCCGCTGTATGTGTATTCGTCCGGCTCGGTGCCGGCGCAGA
AACTGTTCTTCGCGCACAGCGACGCGGGCGACCTGAGCGGACTGATCACCGACTGGTTCGACACCGAAGTCGGCCCCAAG
CGCGAAAGCGCCAGCTATCGCCGCATCGCCGAGCGCATTGGCGTGCCGGGACCGGAGATCCTGTTCCTGTCGGATGTGAT
CGAAGAGCTCGATGCCGCCAAGCGTGCCGGCATGCGCACCGCGCTACTGGACCGCCGGGAGGACTATCCCACGCCGCGTT
CGGCCGACGATGTCGGCAGTCACCAGCGCGTGGAGAGTTTTAGCCAGTTGGTGCTGTAA

Upstream 100 bases:

>100_bases
TCACCGAGCCGGACGGCTGGGTCGGACATTTCACCGGCACCGAAATCGCCAAACAATTCCCCCGCTACGCCCCCGAGAAA
CCTCACAAGGCCAGCTGACG

Downstream 100 bases:

>100_bases
GCACGATCTGCAAGCCGATTGCGCTCGTTGCCGTTTGAGCGCAATCGGTGGTTGGCGCCGCGCAGGCCGCTGATATGCTC
CGGCTGCGACGCGCCGCATG

Product: putative haloacid dehalogenase-like hydrolase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTRPQAILTDIEGTTSSISFVKDVLFPYARRAMPAYVREHGNHPQVRHWLNQVADEIGEDVPDEVLITTLQTWIDEDRKH
TALKALQGLIWGDGYKTADFTAHIYADAAIQLKAWHAAGIPLYVYSSGSVPAQKLFFAHSDAGDLSGLITDWFDTEVGPK
RESASYRRIAERIGVPGPEILFLSDVIEELDAAKRAGMRTALLDRREDYPTPRSADDVGSHQRVESFSQLVL

Sequences:

>Translated_232_residues
MTRPQAILTDIEGTTSSISFVKDVLFPYARRAMPAYVREHGNHPQVRHWLNQVADEIGEDVPDEVLITTLQTWIDEDRKH
TALKALQGLIWGDGYKTADFTAHIYADAAIQLKAWHAAGIPLYVYSSGSVPAQKLFFAHSDAGDLSGLITDWFDTEVGPK
RESASYRRIAERIGVPGPEILFLSDVIEELDAAKRAGMRTALLDRREDYPTPRSADDVGSHQRVESFSQLVL
>Mature_231_residues
TRPQAILTDIEGTTSSISFVKDVLFPYARRAMPAYVREHGNHPQVRHWLNQVADEIGEDVPDEVLITTLQTWIDEDRKHT
ALKALQGLIWGDGYKTADFTAHIYADAAIQLKAWHAAGIPLYVYSSGSVPAQKLFFAHSDAGDLSGLITDWFDTEVGPKR
ESASYRRIAERIGVPGPEILFLSDVIEELDAAKRAGMRTALLDRREDYPTPRSADDVGSHQRVESFSQLVL

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family [H]

Homologues:

Organism=Homo sapiens, GI10864017, Length=251, Percent_Identity=37.4501992031873, Blast_Score=148, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI115533232, Length=221, Percent_Identity=45.2488687782805, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6320797, Length=232, Percent_Identity=36.2068965517241, Blast_Score=121, Evalue=9e-29,
Organism=Drosophila melanogaster, GI281360080, Length=213, Percent_Identity=41.3145539906103, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24644163, Length=213, Percent_Identity=41.3145539906103, Blast_Score=159, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010041
- InterPro:   IPR023214
- InterPro:   IPR006439 [H]

Pfam domain/function: NA

EC number: =3.1.3.77 [H]

Molecular weight: Translated: 25905; Mature: 25774

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPQAILTDIEGTTSSISFVKDVLFPYARRAMPAYVREHGNHPQVRHWLNQVADEIGED
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
VPDEVLITTLQTWIDEDRKHTALKALQGLIWGDGYKTADFTAHIYADAAIQLKAWHAAGI
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEEEECCCC
PLYVYSSGSVPAQKLFFAHSDAGDLSGLITDWFDTEVGPKRESASYRRIAERIGVPGPEI
EEEEEECCCCCHHHHHEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCE
LFLSDVIEELDAAKRAGMRTALLDRREDYPTPRSADDVGSHQRVESFSQLVL
EHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TRPQAILTDIEGTTSSISFVKDVLFPYARRAMPAYVREHGNHPQVRHWLNQVADEIGED
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
VPDEVLITTLQTWIDEDRKHTALKALQGLIWGDGYKTADFTAHIYADAAIQLKAWHAAGI
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEEEECCCC
PLYVYSSGSVPAQKLFFAHSDAGDLSGLITDWFDTEVGPKRESASYRRIAERIGVPGPEI
EEEEEECCCCCHHHHHEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCE
LFLSDVIEELDAAKRAGMRTALLDRREDYPTPRSADDVGSHQRVESFSQLVL
EHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]