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The map label for this gene is ytfL [C]

Identifier: 78047299

GI number: 78047299

Start: 1963167

End: 1964507

Strand: Reverse

Name: ytfL [C]

Synonym: XCV1743

Alternate gene names: 78047299

Gene position: 1964507-1963167 (Counterclockwise)

Preceding gene: 78047303

Following gene: 78047298

Centisome position: 37.94

GC content: 65.32

Gene sequence:

>1341_bases
GTGGTTGAGTTTTTGATCGTCATCGCCCTGATCGTGCTGAATGGCTTCTTCGCCATGTCGGAGATGTCGTTGATGACCTC
GCGCAAGAGCCGCCTGAAGCAGATGGCCGGCTCCAGCAAGCGCGCCGCGCGGGCCCTGGCCCTGGCCGAAAGCCCCGAAA
ACTTCCTGTCCACGGTTCAGATCGGCATCACCCTGATCGGCATCCTGACCGGCGTGTTCGGCGGCGAGGCGATCGGCGAA
GCCATCGCCAGCTGGCTGCAGGGTGTGTTCCCGGCCTTGGCGGGCACGTTCGAACTGGTCGGCAAGCCGCGCCCGTATTC
GGTGGTGATCGGCAGCACCCTGGCGGTGGCGCTGATCACGTTCCTGACGCTGATCTTCGGCGAGCTGGTGCCCAAGCGGC
TGGCGCTGCGCAATTCCGAAGACATCGCAGGCGTTGTCGCGGTGCCGATGGCCTGGCTGGCCAAGATCGCCGCGCCCGGG
GTGTGGGTGCTGGCGCGCTCCACCCGCCTGGTCCTGCGCATGCTGGGCATGGGCAAGGACGAGTCGGCCTCGGTCACCGA
GGAAGAGATCCGCATGCTGGTGGCCGAAAGCCACGAGGCCGGGGTGATCGACGCGCACGAGCGCGACATGATGAATCGCG
TGATGCGGCTGGGCGATCGTACCGCCGACAGCCTGATGACCCCGCGCAACCGCATCGCCTGGCTGGACGCCAACGCCGAG
CCGGAACGCAATCTGCAGGTCATGCGCGAGCACGAATTTTCGCGCTACCCAGTGTACCGCGGCAGCGACCAGGACATTGC
TGGGGTGCTGGAAGTCAAATCGCTGGTCACGCGCATGGACGGCCACGGCGCGCACCTGTTCCAGGCGCTGCGCGACACCT
TGTTCGTGTCCGAATCCACGCACGCGATGAAGCTGCTGGAAATCTTTCGCGAAGAACAGCAGTCGATGGCGCTGGTGGTG
GACGAATACGGCGAAATCCGCGGATTGGTGACCATCAGCGACCTGATGGGCGCAGTGGTCGGCCGTCTGCAGGCGGTGGA
AAATACCGACGAGGACGCGCTGGTGGTCACGCGCGCGGACGGCTCGCTGTTGATCGACGGGTCGCTGCCGGTGGAAGAAT
TGCGCGAAGTCCTCGGTGCCGAACTGCCCGACGCCGACGAGGGCGATTACCACACGCTTGCGGGCCTGTGCATTTACTAT
TTCGGGCGCATTCCGCAGGCCGGCGAGTTCTTCGATTGGGCCGGCTGGCGCATCGAGATCGTCGACCTGGACGGTGCGCG
CGTGGACAAGTTGCTGCTGAGCCGGGTGGGCGACGAGGACAGCGATGACATCGTCGGCTGA

Upstream 100 bases:

>100_bases
GAAGACGACCCTATCCCCCCGTGTTGCCGCCCGGCCTGTGCGCCCGCCGGTAGCCCCAGTGCTCCCCCGCCCTCCCCTTC
ACTAACCGGGGAAGACGCCC

Downstream 100 bases:

>100_bases
CGGCGGTGCACCGCACGATGATGCCAGCGAGCAGATGCGCTACCGCAACGAAGGCATCCGCAGCCTGCTGGCAGCCTTCA
GCGAAGGTGATCCGGACCAG

Product: HlyC/CorC family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MVEFLIVIALIVLNGFFAMSEMSLMTSRKSRLKQMAGSSKRAARALALAESPENFLSTVQIGITLIGILTGVFGGEAIGE
AIASWLQGVFPALAGTFELVGKPRPYSVVIGSTLAVALITFLTLIFGELVPKRLALRNSEDIAGVVAVPMAWLAKIAAPG
VWVLARSTRLVLRMLGMGKDESASVTEEEIRMLVAESHEAGVIDAHERDMMNRVMRLGDRTADSLMTPRNRIAWLDANAE
PERNLQVMREHEFSRYPVYRGSDQDIAGVLEVKSLVTRMDGHGAHLFQALRDTLFVSESTHAMKLLEIFREEQQSMALVV
DEYGEIRGLVTISDLMGAVVGRLQAVENTDEDALVVTRADGSLLIDGSLPVEELREVLGAELPDADEGDYHTLAGLCIYY
FGRIPQAGEFFDWAGWRIEIVDLDGARVDKLLLSRVGDEDSDDIVG

Sequences:

>Translated_446_residues
MVEFLIVIALIVLNGFFAMSEMSLMTSRKSRLKQMAGSSKRAARALALAESPENFLSTVQIGITLIGILTGVFGGEAIGE
AIASWLQGVFPALAGTFELVGKPRPYSVVIGSTLAVALITFLTLIFGELVPKRLALRNSEDIAGVVAVPMAWLAKIAAPG
VWVLARSTRLVLRMLGMGKDESASVTEEEIRMLVAESHEAGVIDAHERDMMNRVMRLGDRTADSLMTPRNRIAWLDANAE
PERNLQVMREHEFSRYPVYRGSDQDIAGVLEVKSLVTRMDGHGAHLFQALRDTLFVSESTHAMKLLEIFREEQQSMALVV
DEYGEIRGLVTISDLMGAVVGRLQAVENTDEDALVVTRADGSLLIDGSLPVEELREVLGAELPDADEGDYHTLAGLCIYY
FGRIPQAGEFFDWAGWRIEIVDLDGARVDKLLLSRVGDEDSDDIVG
>Mature_446_residues
MVEFLIVIALIVLNGFFAMSEMSLMTSRKSRLKQMAGSSKRAARALALAESPENFLSTVQIGITLIGILTGVFGGEAIGE
AIASWLQGVFPALAGTFELVGKPRPYSVVIGSTLAVALITFLTLIFGELVPKRLALRNSEDIAGVVAVPMAWLAKIAAPG
VWVLARSTRLVLRMLGMGKDESASVTEEEIRMLVAESHEAGVIDAHERDMMNRVMRLGDRTADSLMTPRNRIAWLDANAE
PERNLQVMREHEFSRYPVYRGSDQDIAGVLEVKSLVTRMDGHGAHLFQALRDTLFVSESTHAMKLLEIFREEQQSMALVV
DEYGEIRGLVTISDLMGAVVGRLQAVENTDEDALVVTRADGSLLIDGSLPVEELREVLGAELPDADEGDYHTLAGLCIYY
FGRIPQAGEFFDWAGWRIEIVDLDGARVDKLLLSRVGDEDSDDIVG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=381, Percent_Identity=26.7716535433071, Blast_Score=172, Evalue=7e-43,
Organism=Escherichia coli, GI1790664, Length=439, Percent_Identity=28.9293849658314, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI145693175, Length=416, Percent_Identity=29.0865384615385, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI87082033, Length=347, Percent_Identity=29.971181556196, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788119, Length=266, Percent_Identity=30.0751879699248, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786879, Length=245, Percent_Identity=28.1632653061224, Blast_Score=104, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48821; Mature: 48821

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEFLIVIALIVLNGFFAMSEMSLMTSRKSRLKQMAGSSKRAARALALAESPENFLSTVQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHH
IGITLIGILTGVFGGEAIGEAIASWLQGVFPALAGTFELVGKPRPYSVVIGSTLAVALIT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHH
FLTLIFGELVPKRLALRNSEDIAGVVAVPMAWLAKIAAPGVWVLARSTRLVLRMLGMGKD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCC
ESASVTEEEIRMLVAESHEAGVIDAHERDMMNRVMRLGDRTADSLMTPRNRIAWLDANAE
CCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEECCCC
PERNLQVMREHEFSRYPVYRGSDQDIAGVLEVKSLVTRMDGHGAHLFQALRDTLFVSEST
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH
HAMKLLEIFREEQQSMALVVDEYGEIRGLVTISDLMGAVVGRLQAVENTDEDALVVTRAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCCCEEEEEECC
GSLLIDGSLPVEELREVLGAELPDADEGDYHTLAGLCIYYFGRIPQAGEFFDWAGWRIEI
CCEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
VDLDGARVDKLLLSRVGDEDSDDIVG
EECCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVEFLIVIALIVLNGFFAMSEMSLMTSRKSRLKQMAGSSKRAARALALAESPENFLSTVQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHH
IGITLIGILTGVFGGEAIGEAIASWLQGVFPALAGTFELVGKPRPYSVVIGSTLAVALIT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHH
FLTLIFGELVPKRLALRNSEDIAGVVAVPMAWLAKIAAPGVWVLARSTRLVLRMLGMGKD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCC
ESASVTEEEIRMLVAESHEAGVIDAHERDMMNRVMRLGDRTADSLMTPRNRIAWLDANAE
CCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEECCCC
PERNLQVMREHEFSRYPVYRGSDQDIAGVLEVKSLVTRMDGHGAHLFQALRDTLFVSEST
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH
HAMKLLEIFREEQQSMALVVDEYGEIRGLVTISDLMGAVVGRLQAVENTDEDALVVTRAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCCCEEEEEECC
GSLLIDGSLPVEELREVLGAELPDADEGDYHTLAGLCIYYFGRIPQAGEFFDWAGWRIEI
CCEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
VDLDGARVDKLLLSRVGDEDSDDIVG
EECCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]