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The map label for this gene is apaH [H]

Identifier: 78046454

GI number: 78046454

Start: 1026885

End: 1027841

Strand: Reverse

Name: apaH [H]

Synonym: XCV0898

Alternate gene names: 78046454

Gene position: 1027841-1026885 (Counterclockwise)

Preceding gene: 78046455

Following gene: 78046445

Centisome position: 19.85

GC content: 67.4

Gene sequence:

>957_bases
ATGAGCGTCTGGGCCATCGGCGACCTGCAAGGGTGCTACGACATCACCCAGCGGTTGCTGGAGAAGATCAATTTCGACCC
CGCCCAGGACACGCTGTGGTTCTGCGGCGATCTGGTCAACCGCGGCGGGCAATCGCTGGAAACGCTGCGCCTGGTGCATT
CCCTGCGCGCGCACAGCGTAGTGGTGCTGGGCAATCACGACCTGTCGCTGCTGGCGATCGGGGCGCGTTCGGAAGAAGAG
CAGCGCAAGGTCAACCCGGATCTGCTGCGCATCGTGATGGCCGAAGATCGCGATGCGTTGCTGGACTGGCTACGCATGCA
GAAGCTGGCGCACGTGGACCGCACCCTGGGCTGGATGATGATCCATGCCGGGCTGGCGCCGAAGTGGACCACGCAGATGG
CCGAAAAGCATGCACGCGAGGTCGAGCAGCAACTGCAGGGCGGCGGCTATCGCAAGCTGCTGCGCAATATGTACGGCGAC
CAGCCGGGCTGGTCGCCGGGCCTGAGCGGCTACGACCGCAGCCGGGCCATCATCAACCTGTTCACCCGCATGCGCTACTG
CACCCCGCGTGGGCGCATCGCCACCGACGACAAGGGCACGCCGGGGACGCAGGCACAGGGCCTGTATCCCTGGTTCGAAG
TGCCGGGACGGGTCGAGCGCGACCTGAAGATCGTCTGCGGGCATTGGTCCGCACTGGGCCTGACGATCACCCAGGGTGTG
CATGCGATCGATACCGGCGCGGTCTGGGGCGGCAAGCTCACGGCGTTGCAGCTGGATAGCGAGGAGCTGCGCGTGGTGCA
GGTGCCCGGACGGGAAGTGACCGGGCCGGCACCGGTCGCACGCGCACCGCGGCGTCCACGTGAGCGTCAGGGGCGTCAGC
GCTCGCGCGGCAACCGCGGCAATGCGGGGAACGCAGCGGCCGGCCCCAAGCCGTCAGTCGATACGCCACAGGACTGA

Upstream 100 bases:

>100_bases
GCCGACGATGGCACCGAATTTATCGCTCCGATCGCCGCCTTCGTGCTGAGCGTGCCCAGGACGCTGCACTGATGAATGCC
GGAGTAAGGGAGCGCGCGCA

Downstream 100 bases:

>100_bases
GCGCGCGAGGCGCCCGTCGCCATCGCGGTGCCGGGCGCGACCCTGCATCGCTCAGCGGCGTTCGTAATCCACGAACGAAA
ACGCATGGGCATGCCGGGCG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSVWAIGDLQGCYDITQRLLEKINFDPAQDTLWFCGDLVNRGGQSLETLRLVHSLRAHSVVVLGNHDLSLLAIGARSEEE
QRKVNPDLLRIVMAEDRDALLDWLRMQKLAHVDRTLGWMMIHAGLAPKWTTQMAEKHAREVEQQLQGGGYRKLLRNMYGD
QPGWSPGLSGYDRSRAIINLFTRMRYCTPRGRIATDDKGTPGTQAQGLYPWFEVPGRVERDLKIVCGHWSALGLTITQGV
HAIDTGAVWGGKLTALQLDSEELRVVQVPGREVTGPAPVARAPRRPRERQGRQRSRGNRGNAGNAAAGPKPSVDTPQD

Sequences:

>Translated_318_residues
MSVWAIGDLQGCYDITQRLLEKINFDPAQDTLWFCGDLVNRGGQSLETLRLVHSLRAHSVVVLGNHDLSLLAIGARSEEE
QRKVNPDLLRIVMAEDRDALLDWLRMQKLAHVDRTLGWMMIHAGLAPKWTTQMAEKHAREVEQQLQGGGYRKLLRNMYGD
QPGWSPGLSGYDRSRAIINLFTRMRYCTPRGRIATDDKGTPGTQAQGLYPWFEVPGRVERDLKIVCGHWSALGLTITQGV
HAIDTGAVWGGKLTALQLDSEELRVVQVPGREVTGPAPVARAPRRPRERQGRQRSRGNRGNAGNAAAGPKPSVDTPQD
>Mature_317_residues
SVWAIGDLQGCYDITQRLLEKINFDPAQDTLWFCGDLVNRGGQSLETLRLVHSLRAHSVVVLGNHDLSLLAIGARSEEEQ
RKVNPDLLRIVMAEDRDALLDWLRMQKLAHVDRTLGWMMIHAGLAPKWTTQMAEKHAREVEQQLQGGGYRKLLRNMYGDQ
PGWSPGLSGYDRSRAIINLFTRMRYCTPRGRIATDDKGTPGTQAQGLYPWFEVPGRVERDLKIVCGHWSALGLTITQGVH
AIDTGAVWGGKLTALQLDSEELRVVQVPGREVTGPAPVARAPRRPRERQGRQRSRGNRGNAGNAAAGPKPSVDTPQD

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=267, Percent_Identity=44.1947565543071, Blast_Score=218, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 35378; Mature: 35247

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVWAIGDLQGCYDITQRLLEKINFDPAQDTLWFCGDLVNRGGQSLETLRLVHSLRAHSV
CCEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEE
VVLGNHDLSLLAIGARSEEEQRKVNPDLLRIVMAEDRDALLDWLRMQKLAHVDRTLGWMM
EEECCCCEEEEEECCCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IHAGLAPKWTTQMAEKHAREVEQQLQGGGYRKLLRNMYGDQPGWSPGLSGYDRSRAIINL
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
FTRMRYCTPRGRIATDDKGTPGTQAQGLYPWFEVPGRVERDLKIVCGHWSALGLTITQGV
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEECCCHHHHHHHHCCC
HAIDTGAVWGGKLTALQLDSEELRVVQVPGREVTGPAPVARAPRRPRERQGRQRSRGNRG
CEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
NAGNAAAGPKPSVDTPQD
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVWAIGDLQGCYDITQRLLEKINFDPAQDTLWFCGDLVNRGGQSLETLRLVHSLRAHSV
CEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEE
VVLGNHDLSLLAIGARSEEEQRKVNPDLLRIVMAEDRDALLDWLRMQKLAHVDRTLGWMM
EEECCCCEEEEEECCCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IHAGLAPKWTTQMAEKHAREVEQQLQGGGYRKLLRNMYGDQPGWSPGLSGYDRSRAIINL
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
FTRMRYCTPRGRIATDDKGTPGTQAQGLYPWFEVPGRVERDLKIVCGHWSALGLTITQGV
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEECCCHHHHHHHHCCC
HAIDTGAVWGGKLTALQLDSEELRVVQVPGREVTGPAPVARAPRRPRERQGRQRSRGNRG
CEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
NAGNAAAGPKPSVDTPQD
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]