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The map label for this gene is ompR [H]

Identifier: 78046340

GI number: 78046340

Start: 897458

End: 898237

Strand: Reverse

Name: ompR [H]

Synonym: XCV0784

Alternate gene names: 78046340

Gene position: 898237-897458 (Counterclockwise)

Preceding gene: 78046347

Following gene: 78046339

Centisome position: 17.35

GC content: 65.77

Gene sequence:

>780_bases
ATGTATCCGGCAGCCACCACCTTGCGCGGGCCAAGCTCCGCGCCACAGACGATGATCCCTATGGACCTGCAACAACCCTG
CGTTCTCGTGGTCGACGACGATCCGGACCTGCGCAAGCTGATCGGCGAATTTCTGAGCGCTCACGGCTACCAGGTGGATA
TGGCCGAAAACGTGGCGGAGATGCGCTCTGTCATGGCGCAGCGCCGCCCGGACCTCATCGTACTCGACGTGATGATGCCG
GGAGAAGATGGGCTGAGTGCAGCGCGCGCCCTGGCCAGCGAGCGCGGCTCACCTGCGGTCATCATGCTCAGCGCGCTGGG
TAACGACACCGACCGCATCATCGGCCTGGAAGTGGGTGCCGACGATTACCTGGCCAAACCCTGCAATCCGCGCGAATTGC
TGGCCCGTGTGCGCGCCCTGCTGCGGCGCAGCCAGGCCAGCAACGAACAGGCCGACCAGCGCGGAAACGTCTACGAATTC
GCCGGCTGGCGGCTGGACGTGGTGCGCCGCGACCTGCGCGACCCCACCGGCATCTTCATCAATCTGTCCGACGGCGAGTT
CGCGCTGCTGCGCACCTTCGTCGAACACCCGCAGCGCGTGCTCAGCCGCGACCAGCTGCTGGACTACGCCCGCGGCCGCG
ACACCGACGTCTACGACCGCGCCATCGACAGCCAGATCAGCCGCCTGCGCCGCAAAATCAATGAGCGCGTCCATACCGAG
TTGATTCGCACCGTACGCAACGAGGGCTACATGCTGCTGCCGAGCGTCTCGCGCCTGTGA

Upstream 100 bases:

>100_bases
TGCGCGATGTCCTGGTCTGTCATGGTGCGTTACACGTGTGCCAATGGTTGACAAATTCGATCATTATGATGCGTGCTCCA
GCCCTGCAATTGCGAGCACC

Downstream 100 bases:

>100_bases
GCAAACCGGCACGGCGCGGGCTGTCGATCTTTGCGCGGACCTTTGTGTTGTTGGCGGTGGCCCTGGTCACCGCCCAGGCG
GTGGGCATCGCCCTGTTGAT

Product: OmpR family two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MYPAATTLRGPSSAPQTMIPMDLQQPCVLVVDDDPDLRKLIGEFLSAHGYQVDMAENVAEMRSVMAQRRPDLIVLDVMMP
GEDGLSAARALASERGSPAVIMLSALGNDTDRIIGLEVGADDYLAKPCNPRELLARVRALLRRSQASNEQADQRGNVYEF
AGWRLDVVRRDLRDPTGIFINLSDGEFALLRTFVEHPQRVLSRDQLLDYARGRDTDVYDRAIDSQISRLRRKINERVHTE
LIRTVRNEGYMLLPSVSRL

Sequences:

>Translated_259_residues
MYPAATTLRGPSSAPQTMIPMDLQQPCVLVVDDDPDLRKLIGEFLSAHGYQVDMAENVAEMRSVMAQRRPDLIVLDVMMP
GEDGLSAARALASERGSPAVIMLSALGNDTDRIIGLEVGADDYLAKPCNPRELLARVRALLRRSQASNEQADQRGNVYEF
AGWRLDVVRRDLRDPTGIFINLSDGEFALLRTFVEHPQRVLSRDQLLDYARGRDTDVYDRAIDSQISRLRRKINERVHTE
LIRTVRNEGYMLLPSVSRL
>Mature_259_residues
MYPAATTLRGPSSAPQTMIPMDLQQPCVLVVDDDPDLRKLIGEFLSAHGYQVDMAENVAEMRSVMAQRRPDLIVLDVMMP
GEDGLSAARALASERGSPAVIMLSALGNDTDRIIGLEVGADDYLAKPCNPRELLARVRALLRRSQASNEQADQRGNVYEF
AGWRLDVVRRDLRDPTGIFINLSDGEFALLRTFVEHPQRVLSRDQLLDYARGRDTDVYDRAIDSQISRLRRKINERVHTE
LIRTVRNEGYMLLPSVSRL

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=238, Percent_Identity=44.1176470588235, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=37.2294372294372, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1788394, Length=242, Percent_Identity=35.5371900826446, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=37.3913043478261, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=37.3390557939914, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=38.961038961039, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36.4444444444444, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=32.3529411764706, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790860, Length=238, Percent_Identity=31.9327731092437, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=32.7510917030568, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=33.0357142857143, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=32.5991189427313, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786911, Length=208, Percent_Identity=31.7307692307692, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=33.0434782608696, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790299, Length=135, Percent_Identity=30.3703703703704, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=28.3018867924528, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29133; Mature: 29133

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPAATTLRGPSSAPQTMIPMDLQQPCVLVVDDDPDLRKLIGEFLSAHGYQVDMAENVAE
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEHHHHHHHH
MRSVMAQRRPDLIVLDVMMPGEDGLSAARALASERGSPAVIMLSALGNDTDRIIGLEVGA
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEECC
DDYLAKPCNPRELLARVRALLRRSQASNEQADQRGNVYEFAGWRLDVVRRDLRDPTGIFI
CHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCHHHHHHHHCCCCCEEEE
NLSDGEFALLRTFVEHPQRVLSRDQLLDYARGRDTDVYDRAIDSQISRLRRKINERVHTE
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LIRTVRNEGYMLLPSVSRL
HHHHHHCCCEEEECCHHCC
>Mature Secondary Structure
MYPAATTLRGPSSAPQTMIPMDLQQPCVLVVDDDPDLRKLIGEFLSAHGYQVDMAENVAE
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEHHHHHHHH
MRSVMAQRRPDLIVLDVMMPGEDGLSAARALASERGSPAVIMLSALGNDTDRIIGLEVGA
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEECC
DDYLAKPCNPRELLARVRALLRRSQASNEQADQRGNVYEFAGWRLDVVRRDLRDPTGIFI
CHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCHHHHHHHHCCCCCEEEE
NLSDGEFALLRTFVEHPQRVLSRDQLLDYARGRDTDVYDRAIDSQISRLRRKINERVHTE
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LIRTVRNEGYMLLPSVSRL
HHHHHHCCCEEEECCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]