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The map label for this gene is tcp [H]

Identifier: 78046225

GI number: 78046225

Start: 756210

End: 758414

Strand: Reverse

Name: tcp [H]

Synonym: XCV0669

Alternate gene names: 78046225

Gene position: 758414-756210 (Counterclockwise)

Preceding gene: 78046226

Following gene: 78046224

Centisome position: 14.65

GC content: 64.22

Gene sequence:

>2205_bases
ATGCCTGTTGTTTCCCTCTTGCGTCGTTCTGTTGCCAATCTCCCGCTCACCCGAAAGTTCGTCCTGTTGTGCACGCTATT
GACCGTGGGCGTGATCCTGCTGGCGATGGCCGCCGCGCGCCTGCAATATCTGGATCTGGTGGAGGCGCGCAAGCTCAGCG
TCAAGACCGAGGTGGAGATGGGCCTGACGGTGATGCAGCACTATGCCGACAAGGTCAAAGCCGGCGAGCTGAGCCTGGAG
CAAGCCAAGGAAGCCGCGCGCACCACGCTGGCCGACATGCGCACCAACGACGGGGTGGATTACTTCTTCATCGTCGACCC
GCAGATGCGCATCCTGATGCATCCCAAGCGCCCGGTCGGCACCGACATGACCGACTACAAGAGCGATGCCGGGCAATACG
TGTATCGCGACATCAAGACCGCCATCGATAGCGGCGACGGCTTCAGCTATTACGACGCGCCCAAGCCGGGCAAGAAGGAA
CAGCTACCGAAGATCAGCTATGCCAAGACCTTTCCGGCCTGGAACTGGGTGCTGGTGATGGGCGTGTATGCCGAAGACAT
CCAAGTGCAGGCGTGGGGTTTCACGCGCACCCTGACCTTGATCGGCGGCGCCCTGGTGGCGCTGGTGATCGGGCTGTGCT
GGCTGATCGCCTCGGCCATGGCCGCGCCGCTGCGCGCTGCCTCGCGCACTGCCGAAGCCATCGCCTCGGGCCGCTTCGAC
AACGACATCCGCGTGGAATCGCGCGATGAAACCGGCCAGCTGATGCACAGCATGCAGCAGATGCAGACCCAGCTGCAGCG
CTTCAACGGCGAGATGCAGACCATGATCCGCCTGCAGCAGGGCGAGAACATCGCGCACCGCATTCCGGAAGATTTCCCCG
GCGATTACGGCACGCTGGCGCACGGCGTCAACACGGTGGTATTCGAACATCTAGATGCCATCAACGAAGCGATGGACGTG
ATGAGCGACTACGGCCGTGGCGATCTGCGCCGCGACATGCGTCGCCTGCCCGGCCAGCGCGCAGCCTTGCATCAGGCGCT
GGATACGGTGAAAGAGAATCTGTCTGCAATCAACAGCGACATCGCGCGCCTGGCCGATGCAGCTGCGCGCGGCGATTTCT
CCGCACGTGGCGACCAATCGCATTACCAGTTCGCGTTTGCGGAAATGGTGCAGGCGCTGAACCGGCTGATGCAGCAGGCC
GACGCCGGGTTGGACGATGTGGGCCGCATCATGGCCGCGATCGCCGACGGCGACCTGTCGCAGCGCGTGGAGTCGCATTA
CGAAGGCGCGTTCGGTCGCCTGGCCGATGCAGCCAACCGCACCGCCATCCAATTGACCAGCATCGTGCAGGGCATCCAGC
ACTCGGCCGAGATGATCAATACCGCGGCAGGCGAGATCGCCAGCGGCAATGCCGACCTGTCCACGCGCACCGAGCATCAG
GCAGCGAACCTGGAAGAAACCGCCGCTTCGATGGAAGAACTCACCTCCACCGTGCGCCAGAACGCCGACAACGCGCGCCA
GGCCAACCAACTGGTCAAGGGCACCGGCGATGTGGCCGAGAGCGGCGGCCGCGTGGTGCAGGAAGTGGTGAGCACCATGC
AGGCGATCACGCAATCGTCGGCGCGTATTTCCGACATCATCGGGGTGATCGACGGCATCGCCTTCCAGACCAACATCCTG
GCGCTGAATGCGGCCGTGGAAGCAGCGCGCGCAGGCGAGCAAGGCCGTGGCTTTGCCGTGGTCGCCACCGAAGTGCGCGC
CCTGGCGCAGCGCTCGGCCGGTGCTGCCAAGGAAATCAAGCAGCTGATTTCCGATTCGGTGGAAAAAGTGGCGCAGGGTT
CGGAGCTGGTGCAACAGGCCGGCAGCACCATGACCGAGGTGGTCAGCTCGGTGAAGCGCGTGACCGACATCATGGCCGAG
ATCACCGCGGCCAGCACCGAACAAAGCGCCGGCATCGAACAGGTCAGCACCACGGTGATGCAGCTGGACGAAATGACCCA
GCAAAACGCCGCACTGGTGGAAGAAGCCACCGCGGCCGCGCGCAGCATGGAAGACCAGGCAGCAGACCTGACCCGCGCCG
TGGCGGTGTTCCGGCTGACATCGGATGCCGGAACACCGCCGGTACGTGGCGCAACGAACGCGCTTGCCGCTACGAAGCCG
GCGGCCGCCAAGCACGCTGTGCACGAGCACAGGCGACGTGCGTGA

Upstream 100 bases:

>100_bases
ATCGCCTGAGCGGACGCTGCCGCAGTTAGTATTCAACCTGCATGTGAATCAGCCGCTATCCATGATGTAGCGCCGTGCGC
GCGTTCTGGATGTCGTTGTC

Downstream 100 bases:

>100_bases
GCGATATCGCCTGCCACGCACACGAGCGCTCGCGCCTGTGCGGCAGGCGATGTCGGTGGCATGTGCAGCAATCACGGCGA
CTGATGGTTTGGGATCGGCA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 734; Mature: 733

Protein sequence:

>734_residues
MPVVSLLRRSVANLPLTRKFVLLCTLLTVGVILLAMAAARLQYLDLVEARKLSVKTEVEMGLTVMQHYADKVKAGELSLE
QAKEAARTTLADMRTNDGVDYFFIVDPQMRILMHPKRPVGTDMTDYKSDAGQYVYRDIKTAIDSGDGFSYYDAPKPGKKE
QLPKISYAKTFPAWNWVLVMGVYAEDIQVQAWGFTRTLTLIGGALVALVIGLCWLIASAMAAPLRAASRTAEAIASGRFD
NDIRVESRDETGQLMHSMQQMQTQLQRFNGEMQTMIRLQQGENIAHRIPEDFPGDYGTLAHGVNTVVFEHLDAINEAMDV
MSDYGRGDLRRDMRRLPGQRAALHQALDTVKENLSAINSDIARLADAAARGDFSARGDQSHYQFAFAEMVQALNRLMQQA
DAGLDDVGRIMAAIADGDLSQRVESHYEGAFGRLADAANRTAIQLTSIVQGIQHSAEMINTAAGEIASGNADLSTRTEHQ
AANLEETAASMEELTSTVRQNADNARQANQLVKGTGDVAESGGRVVQEVVSTMQAITQSSARISDIIGVIDGIAFQTNIL
ALNAAVEAARAGEQGRGFAVVATEVRALAQRSAGAAKEIKQLISDSVEKVAQGSELVQQAGSTMTEVVSSVKRVTDIMAE
ITAASTEQSAGIEQVSTTVMQLDEMTQQNAALVEEATAAARSMEDQAADLTRAVAVFRLTSDAGTPPVRGATNALAATKP
AAAKHAVHEHRRRA

Sequences:

>Translated_734_residues
MPVVSLLRRSVANLPLTRKFVLLCTLLTVGVILLAMAAARLQYLDLVEARKLSVKTEVEMGLTVMQHYADKVKAGELSLE
QAKEAARTTLADMRTNDGVDYFFIVDPQMRILMHPKRPVGTDMTDYKSDAGQYVYRDIKTAIDSGDGFSYYDAPKPGKKE
QLPKISYAKTFPAWNWVLVMGVYAEDIQVQAWGFTRTLTLIGGALVALVIGLCWLIASAMAAPLRAASRTAEAIASGRFD
NDIRVESRDETGQLMHSMQQMQTQLQRFNGEMQTMIRLQQGENIAHRIPEDFPGDYGTLAHGVNTVVFEHLDAINEAMDV
MSDYGRGDLRRDMRRLPGQRAALHQALDTVKENLSAINSDIARLADAAARGDFSARGDQSHYQFAFAEMVQALNRLMQQA
DAGLDDVGRIMAAIADGDLSQRVESHYEGAFGRLADAANRTAIQLTSIVQGIQHSAEMINTAAGEIASGNADLSTRTEHQ
AANLEETAASMEELTSTVRQNADNARQANQLVKGTGDVAESGGRVVQEVVSTMQAITQSSARISDIIGVIDGIAFQTNIL
ALNAAVEAARAGEQGRGFAVVATEVRALAQRSAGAAKEIKQLISDSVEKVAQGSELVQQAGSTMTEVVSSVKRVTDIMAE
ITAASTEQSAGIEQVSTTVMQLDEMTQQNAALVEEATAAARSMEDQAADLTRAVAVFRLTSDAGTPPVRGATNALAATKP
AAAKHAVHEHRRRA
>Mature_733_residues
PVVSLLRRSVANLPLTRKFVLLCTLLTVGVILLAMAAARLQYLDLVEARKLSVKTEVEMGLTVMQHYADKVKAGELSLEQ
AKEAARTTLADMRTNDGVDYFFIVDPQMRILMHPKRPVGTDMTDYKSDAGQYVYRDIKTAIDSGDGFSYYDAPKPGKKEQ
LPKISYAKTFPAWNWVLVMGVYAEDIQVQAWGFTRTLTLIGGALVALVIGLCWLIASAMAAPLRAASRTAEAIASGRFDN
DIRVESRDETGQLMHSMQQMQTQLQRFNGEMQTMIRLQQGENIAHRIPEDFPGDYGTLAHGVNTVVFEHLDAINEAMDVM
SDYGRGDLRRDMRRLPGQRAALHQALDTVKENLSAINSDIARLADAAARGDFSARGDQSHYQFAFAEMVQALNRLMQQAD
AGLDDVGRIMAAIADGDLSQRVESHYEGAFGRLADAANRTAIQLTSIVQGIQHSAEMINTAAGEIASGNADLSTRTEHQA
ANLEETAASMEELTSTVRQNADNARQANQLVKGTGDVAESGGRVVQEVVSTMQAITQSSARISDIIGVIDGIAFQTNILA
LNAAVEAARAGEQGRGFAVVATEVRALAQRSAGAAKEIKQLISDSVEKVAQGSELVQQAGSTMTEVVSSVKRVTDIMAEI
TAASTEQSAGIEQVSTTVMQLDEMTQQNAALVEEATAAARSMEDQAADLTRAVAVFRLTSDAGTPPVRGATNALAATKPA
AAKHAVHEHRRRA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=286, Percent_Identity=61.5384615384615, Blast_Score=288, Evalue=7e-79,
Organism=Escherichia coli, GI1788195, Length=317, Percent_Identity=54.5741324921136, Blast_Score=287, Evalue=2e-78,
Organism=Escherichia coli, GI1787690, Length=298, Percent_Identity=56.3758389261745, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1788194, Length=255, Percent_Identity=60.3921568627451, Blast_Score=276, Evalue=5e-75,
Organism=Escherichia coli, GI1789453, Length=232, Percent_Identity=44.3965517241379, Blast_Score=182, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 79269; Mature: 79138

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVVSLLRRSVANLPLTRKFVLLCTLLTVGVILLAMAAARLQYLDLVEARKLSVKTEVEM
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLTVMQHYADKVKAGELSLEQAKEAARTTLADMRTNDGVDYFFIVDPQMRILMHPKRPVG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCCC
TDMTDYKSDAGQYVYRDIKTAIDSGDGFSYYDAPKPGKKEQLPKISYAKTFPAWNWVLVM
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCHHHHCCCCCCHHHEE
GVYAEDIQVQAWGFTRTLTLIGGALVALVIGLCWLIASAMAAPLRAASRTAEAIASGRFD
EEHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NDIRVESRDETGQLMHSMQQMQTQLQRFNGEMQTMIRLQQGENIAHRIPEDFPGDYGTLA
CCCEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCCCCCCHHHHH
HGVNTVVFEHLDAINEAMDVMSDYGRGDLRRDMRRLPGQRAALHQALDTVKENLSAINSD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IARLADAAARGDFSARGDQSHYQFAFAEMVQALNRLMQQADAGLDDVGRIMAAIADGDLS
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
QRVESHYEGAFGRLADAANRTAIQLTSIVQGIQHSAEMINTAAGEIASGNADLSTRTEHQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
AANLEETAASMEELTSTVRQNADNARQANQLVKGTGDVAESGGRVVQEVVSTMQAITQSS
HCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHH
ARISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRALAQRSAGAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCHHHHHH
QLISDSVEKVAQGSELVQQAGSTMTEVVSSVKRVTDIMAEITAASTEQSAGIEQVSTTVM
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHH
QLDEMTQQNAALVEEATAAARSMEDQAADLTRAVAVFRLTSDAGTPPVRGATNALAATKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCC
AAAKHAVHEHRRRA
HHHHHHHHHHHCCC
>Mature Secondary Structure 
PVVSLLRRSVANLPLTRKFVLLCTLLTVGVILLAMAAARLQYLDLVEARKLSVKTEVEM
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLTVMQHYADKVKAGELSLEQAKEAARTTLADMRTNDGVDYFFIVDPQMRILMHPKRPVG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCCC
TDMTDYKSDAGQYVYRDIKTAIDSGDGFSYYDAPKPGKKEQLPKISYAKTFPAWNWVLVM
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCHHHHCCCCCCHHHEE
GVYAEDIQVQAWGFTRTLTLIGGALVALVIGLCWLIASAMAAPLRAASRTAEAIASGRFD
EEHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NDIRVESRDETGQLMHSMQQMQTQLQRFNGEMQTMIRLQQGENIAHRIPEDFPGDYGTLA
CCCEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCCCCCCHHHHH
HGVNTVVFEHLDAINEAMDVMSDYGRGDLRRDMRRLPGQRAALHQALDTVKENLSAINSD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IARLADAAARGDFSARGDQSHYQFAFAEMVQALNRLMQQADAGLDDVGRIMAAIADGDLS
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
QRVESHYEGAFGRLADAANRTAIQLTSIVQGIQHSAEMINTAAGEIASGNADLSTRTEHQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
AANLEETAASMEELTSTVRQNADNARQANQLVKGTGDVAESGGRVVQEVVSTMQAITQSS
HCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHH
ARISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRALAQRSAGAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCHHHHHH
QLISDSVEKVAQGSELVQQAGSTMTEVVSSVKRVTDIMAEITAASTEQSAGIEQVSTTVM
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHH
QLDEMTQQNAALVEEATAAARSMEDQAADLTRAVAVFRLTSDAGTPPVRGATNALAATKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCC
AAAKHAVHEHRRRA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]