Click here to switch to the map view.

The map label for this gene is ywbI [H]

Identifier: 78046098

GI number: 78046098

Start: 607463

End: 608464

Strand: Reverse

Name: ywbI [H]

Synonym: XCV0542

Alternate gene names: 78046098

Gene position: 608464-607463 (Counterclockwise)

Preceding gene: 78046100

Following gene: 78046097

Centisome position: 11.75

GC content: 67.86

Gene sequence:

>1002_bases
ATGGCTGCTGCCTGGTCAAGGAATGTGCACAGTGTGGGCAGCCGACACGCATCTTTCCAATGTATTGTTTTCACCGTCGC
CATCTTTTTTCGAGATTGCATGCTGACCTTGCGCCAACTGGAATTTGCCATTGCCGTGGCCGAAGAAGGCGGCTTCACCG
CTGCTGCGCGCCGCTGCAACACCGTGCAATCGGCGCTCAGCCACCAGGTCGCCAAGATCGAAGAGACCTTCGGCGCACGC
CTGTTCGAACGCGGCATCCGCCAGGTGCGGCCCACCGCCGCCGGCGAGGTGTTCCTGCACAACGCCCGCCAGACCCTGCG
CGCTGCCGAGCGCCTGCACGAGGAAATGGCGCAGGCCCTGGGTACCGTGCGCGGGCGGCTGGCGTTGGGGCAGATTTCCT
CGCTCACCACCGTGCAACTGCCGGCGTTGCTACAGCAGTTCCGCAGCGCGCATGCGCGGGTGGACGTGCATCTGCGCACC
GCCATGAGCGAGGCCTTGCTGCACGATCTGGGCGAAGGCCGGCTGGATGTCGCCCTGGTGGGGGTCGGCCCGCAGCTTGC
GGTGCCGGCGCAGCGCCTGCTGCTGCATGAAGAGGCCTTGGCCTTGATCGTGGCACCGGGCCACCGCTTTGCCGCACGCA
AACGGGTGGCACTGGCCGAGCTGGACGACGAACCGATGGCCGGGCTGGTTCCCGGTGCCGGCGTGCGCGGCATCATCGAT
GCTGCGTTTGCGCACGGGGGCCTGCGGCAACGCCAGCAGTACGAAGTCACCCACGCCGATCTGGTGCGCGAACTGGTCGC
CGCCAACCTGGGCGTGGGCATCGTCCCGCAGACCATGGCCGGGGCCATGCACGGCGTGGTCACGGTGGCCTTGAAGGAGC
GTTACCGCTTTCTGACCTACGCGGTGTGGCGGCCCGATCCCAGCCCGGCCGCACGCGCCTTCGTGGCCTTGCTGCGCGCC
CAGCTCGCGCAACGCAGGCCGCCGGCACGTAGAAGCCGCTGA

Upstream 100 bases:

>100_bases
CTGGGCGTAGTAATTGCTCGCCACCGCCAACCCGGTGGCGGCAGCCATCAGCAGCACCAGGCGACGGGGCAAGGGCGGGT
GGGAGGTGGGCTCGGTCTGC

Downstream 100 bases:

>100_bases
ACGCAGCCGCCATCCACCAGCACGCCGTGGAAGCCTGCTAGGCTGCGCGCGTTCGCAAAGGAAACTGCATGTCCGGTCAC
AGTCAGTTCGCCCTGCTCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAAAWSRNVHSVGSRHASFQCIVFTVAIFFRDCMLTLRQLEFAIAVAEEGGFTAAARRCNTVQSALSHQVAKIEETFGAR
LFERGIRQVRPTAAGEVFLHNARQTLRAAERLHEEMAQALGTVRGRLALGQISSLTTVQLPALLQQFRSAHARVDVHLRT
AMSEALLHDLGEGRLDVALVGVGPQLAVPAQRLLLHEEALALIVAPGHRFAARKRVALAELDDEPMAGLVPGAGVRGIID
AAFAHGGLRQRQQYEVTHADLVRELVAANLGVGIVPQTMAGAMHGVVTVALKERYRFLTYAVWRPDPSPAARAFVALLRA
QLAQRRPPARRSR

Sequences:

>Translated_333_residues
MAAAWSRNVHSVGSRHASFQCIVFTVAIFFRDCMLTLRQLEFAIAVAEEGGFTAAARRCNTVQSALSHQVAKIEETFGAR
LFERGIRQVRPTAAGEVFLHNARQTLRAAERLHEEMAQALGTVRGRLALGQISSLTTVQLPALLQQFRSAHARVDVHLRT
AMSEALLHDLGEGRLDVALVGVGPQLAVPAQRLLLHEEALALIVAPGHRFAARKRVALAELDDEPMAGLVPGAGVRGIID
AAFAHGGLRQRQQYEVTHADLVRELVAANLGVGIVPQTMAGAMHGVVTVALKERYRFLTYAVWRPDPSPAARAFVALLRA
QLAQRRPPARRSR
>Mature_332_residues
AAAWSRNVHSVGSRHASFQCIVFTVAIFFRDCMLTLRQLEFAIAVAEEGGFTAAARRCNTVQSALSHQVAKIEETFGARL
FERGIRQVRPTAAGEVFLHNARQTLRAAERLHEEMAQALGTVRGRLALGQISSLTTVQLPALLQQFRSAHARVDVHLRTA
MSEALLHDLGEGRLDVALVGVGPQLAVPAQRLLLHEEALALIVAPGHRFAARKRVALAELDDEPMAGLVPGAGVRGIIDA
AFAHGGLRQRQQYEVTHADLVRELVAANLGVGIVPQTMAGAMHGVVTVALKERYRFLTYAVWRPDPSPAARAFVALLRAQ
LAQRRPPARRSR

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=246, Percent_Identity=28.4552845528455, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI157672245, Length=257, Percent_Identity=29.5719844357977, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787879, Length=308, Percent_Identity=33.1168831168831, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788887, Length=294, Percent_Identity=28.2312925170068, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787806, Length=274, Percent_Identity=25.9124087591241, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787530, Length=243, Percent_Identity=24.2798353909465, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367136, Length=268, Percent_Identity=25.3731343283582, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081904, Length=245, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787601, Length=177, Percent_Identity=28.2485875706215, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI145693105, Length=294, Percent_Identity=26.1904761904762, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789204, Length=244, Percent_Identity=26.2295081967213, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=24.0963855421687, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788297, Length=262, Percent_Identity=25.1908396946565, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790262, Length=270, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790208, Length=248, Percent_Identity=26.6129032258064, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787949, Length=156, Percent_Identity=28.8461538461538, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36287; Mature: 36155

Theoretical pI: Translated: 11.40; Mature: 11.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAWSRNVHSVGSRHASFQCIVFTVAIFFRDCMLTLRQLEFAIAVAEEGGFTAAARRCN
CCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHH
TVQSALSHQVAKIEETFGARLFERGIRQVRPTAAGEVFLHNARQTLRAAERLHEEMAQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTVRGRLALGQISSLTTVQLPALLQQFRSAHARVDVHLRTAMSEALLHDLGEGRLDVALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCCCEEEEEE
GVGPQLAVPAQRLLLHEEALALIVAPGHRFAARKRVALAELDDEPMAGLVPGAGVRGIID
ECCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
AAFAHGGLRQRQQYEVTHADLVRELVAANLGVGIVPQTMAGAMHGVVTVALKERYRFLTY
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEE
AVWRPDPSPAARAFVALLRAQLAQRRPPARRSR
EEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AAAWSRNVHSVGSRHASFQCIVFTVAIFFRDCMLTLRQLEFAIAVAEEGGFTAAARRCN
CCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHH
TVQSALSHQVAKIEETFGARLFERGIRQVRPTAAGEVFLHNARQTLRAAERLHEEMAQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTVRGRLALGQISSLTTVQLPALLQQFRSAHARVDVHLRTAMSEALLHDLGEGRLDVALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCCCEEEEEE
GVGPQLAVPAQRLLLHEEALALIVAPGHRFAARKRVALAELDDEPMAGLVPGAGVRGIID
ECCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
AAFAHGGLRQRQQYEVTHADLVRELVAANLGVGIVPQTMAGAMHGVVTVALKERYRFLTY
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEE
AVWRPDPSPAARAFVALLRAQLAQRRPPARRSR
EEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]