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The map label for this gene is hrcR [C]

Identifier: 78045978

GI number: 78045978

Start: 471999

End: 472643

Strand: Reverse

Name: hrcR [C]

Synonym: XCV0422

Alternate gene names: 78045978

Gene position: 472643-471999 (Counterclockwise)

Preceding gene: 78045979

Following gene: 78045977

Centisome position: 9.13

GC content: 59.69

Gene sequence:

>645_bases
ATGCAGATGCCTGACGTCGGCTCGCTGCTGCTGGTGGTCATCATGCTGGGCTTGCTGCCCTTCGCAGCGATGGTGGTCAC
CTCCTACACCAAGATCGTGGTCGTGCTCGGCCTGCTGCGCAATGCGATCGGGGTACAGCAGGTGCCGCCCAACATGGTCC
TCAATGGCGTTGCATTGCTGGTGTCGTGCTTTGTGATGGCCCCGGTGGGCATGGAGGCGTTCAAGGCCGCACAGAACTAC
GGCGCCGGGTCGGATAACAGCCGCGTGGTGGTGCTGCTCGACGCCTGCCGGGAGCCGTTTCGGCAATTCCTCCTCAAACA
TACACGCGAGCGCGAAAAGGCGTTTTTCATGCGTTCTGCACAGCAGATCTGGCCCAAGGACAAGGCCGCCACGCTCAAGT
CGGACGACTTGCTGGTCTTGGCACCGGCATTCACGCTCAGCGAATTGACCGAAGCCTTCCGTATCGGGTTTCTGTTGTAT
CTGGTGTTTATCGTCATCGATCTGGTGGTGGCCAACGCGCTGATGGCGATGGGCCTTTCACAGGTCACTCCGACCAATGT
GGCGATCCCGTTCAAGCTGCTGTTGTTTGTCGCCATGGACGGCTGGTCGATGCTGATTCACGGCCTGGTTCTGAGCTATC
GGTGA

Upstream 100 bases:

>100_bases
ATCCGCCTGGTCGTTTACGGCCAGACCATCGGCACCGGCAGGCTGCTGGCAGTGGGCGAACATCTGGGTGTGCAGATCCT
CAGCATGTCGGAGAGCACGC

Downstream 100 bases:

>100_bases
CGCCATGGACCATGACGATCTAGTGCGATTCACTTCCGAAGCCTTGCTGCTCTGCCTCAAGGTGTCCTTGCCGGTGGTCG
GTGTCGCTGCGTTGGCCGGG

Product: type III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MQMPDVGSLLLVVIMLGLLPFAAMVVTSYTKIVVVLGLLRNAIGVQQVPPNMVLNGVALLVSCFVMAPVGMEAFKAAQNY
GAGSDNSRVVVLLDACREPFRQFLLKHTREREKAFFMRSAQQIWPKDKAATLKSDDLLVLAPAFTLSELTEAFRIGFLLY
LVFIVIDLVVANALMAMGLSQVTPTNVAIPFKLLLFVAMDGWSMLIHGLVLSYR

Sequences:

>Translated_214_residues
MQMPDVGSLLLVVIMLGLLPFAAMVVTSYTKIVVVLGLLRNAIGVQQVPPNMVLNGVALLVSCFVMAPVGMEAFKAAQNY
GAGSDNSRVVVLLDACREPFRQFLLKHTREREKAFFMRSAQQIWPKDKAATLKSDDLLVLAPAFTLSELTEAFRIGFLLY
LVFIVIDLVVANALMAMGLSQVTPTNVAIPFKLLLFVAMDGWSMLIHGLVLSYR
>Mature_214_residues
MQMPDVGSLLLVVIMLGLLPFAAMVVTSYTKIVVVLGLLRNAIGVQQVPPNMVLNGVALLVSCFVMAPVGMEAFKAAQNY
GAGSDNSRVVVLLDACREPFRQFLLKHTREREKAFFMRSAQQIWPKDKAATLKSDDLLVLAPAFTLSELTEAFRIGFLLY
LVFIVIDLVVANALMAMGLSQVTPTNVAIPFKLLLFVAMDGWSMLIHGLVLSYR

Specific function: Important for pathogenicity [H]

COG id: COG4790

COG function: function code U; Type III secretory pathway, component EscR

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliP/mopC/spaP family [H]

Homologues:

Organism=Escherichia coli, GI1788259, Length=205, Percent_Identity=37.5609756097561, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005838
- InterPro:   IPR005773 [H]

Pfam domain/function: PF00813 FliP [H]

EC number: NA

Molecular weight: Translated: 23491; Mature: 23491

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS01060 FLIP_1 ; PS01061 FLIP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMPDVGSLLLVVIMLGLLPFAAMVVTSYTKIVVVLGLLRNAIGVQQVPPNMVLNGVALL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VSCFVMAPVGMEAFKAAQNYGAGSDNSRVVVLLDACREPFRQFLLKHTREREKAFFMRSA
HHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQIWPKDKAATLKSDDLLVLAPAFTLSELTEAFRIGFLLYLVFIVIDLVVANALMAMGLS
HHHCCCCHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVTPTNVAIPFKLLLFVAMDGWSMLIHGLVLSYR
HCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQMPDVGSLLLVVIMLGLLPFAAMVVTSYTKIVVVLGLLRNAIGVQQVPPNMVLNGVALL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VSCFVMAPVGMEAFKAAQNYGAGSDNSRVVVLLDACREPFRQFLLKHTREREKAFFMRSA
HHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQIWPKDKAATLKSDDLLVLAPAFTLSELTEAFRIGFLLYLVFIVIDLVVANALMAMGLS
HHHCCCCHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVTPTNVAIPFKLLLFVAMDGWSMLIHGLVLSYR
HCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1312532 [H]