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The map label for this gene is gidA [H]

Identifier: 78045947

GI number: 78045947

Start: 445051

End: 446955

Strand: Reverse

Name: gidA [H]

Synonym: XCV0391

Alternate gene names: 78045947

Gene position: 446955-445051 (Counterclockwise)

Preceding gene: 78045948

Following gene: 78045946

Centisome position: 8.63

GC content: 67.72

Gene sequence:

>1905_bases
ATGTCCGACTCCTTCTATCGCTACGACGTCATCGTGATCGGTGGCGGTCATGCCGGCACCGAGGCCGCCCTGGCGTCTGC
ACGCACAGGGGCGCGCACCTTGTTGCTCACCCACAACATCGAGACAGTGGGCGCGATGAGCTGTAACCCGGCCATCGGCG
GAATCGGCAAGGGCCACCTGGTCAAGGAGATCGACGGACTCGGCGGGGCGATGGCACGCGCCGCGGATCTGGCCGGCATC
CAGTGGCGCACGCTCAACGCCTCCAAGGGGCCGGCAGTGCGTGCCACGCGCTGCCAGGCCGATCGCAACCTGTACCGCAC
TGCGATCCGCTGCATCGTCGAGGCCCAGCCCAACCTGACCGTCTTCCAGGCGGCAGTGGACGACCTGATCATCCACAACG
GCACGTCCGAAGCCGACAGCGTGCGCGGCGTCATCACCCAGACCGGGCTGCGTTTCCAAGCGCCTTCGGTGGTGCTGACC
GCCGGGACGTTCCTGGCCGGCAAGATCCATGTCGGCGAAACCCAGTACGCGGCCGGGCGCATGGGCGACCCGCCGGCCAC
CACGCTGGCCGCGCGCCTGCGCGAGCGCCCGTTCGCGATCGACCGGCTCAAGACCGGCACCCCGCCGCGGATCGACGGGC
GCACCCTCGATTACGGCGTGATGGCCGAACAACCCGGCGACGACCCATTGCCGGTGATGTCGTTCATGGGCCAGGTCAGC
GACCATCCGCGCCAGGTCAGCTGCTGGATCACCCAGACCACCGAACAGACCCACGAGATCATTCGCAACGCGCTGCACCG
CTCGCCGCTGTATTCGGGGCAGATCGAAGGCATCGGCCCGCGCTACTGCCCGTCGATCGAAGACAAGGTGGTGCGTTTTG
CCGAGAAGACCAGCCACCAGATCTTCGTCGAACCCGAAGGGCTGGAGGTGGCCGAGATCTATCCCAACGGTATTTCCACC
TCGCTGCCGTTCGATGTGCAGCTGGCGCTGGTGCGCTCGATCCACGGCTTTGCGAACGCGCACATCACCCGCCCCGGCTA
CGCCATCGAATACGACTTCTTCGACCCGCGCGGGCTCAAGGCCTCGCTGGAGACCAAGGCGGTGGGCGGGCTGTTCTTCG
CCGGGCAGATCAACGGCACCACCGGTTACGAAGAGGCCGCCGCCCAGGGTCTGCTGGCCGGACTCAACGCAGCGCGCCAC
GTGCAGGGGCTGCCGGCGTGGTCGCCGCGCCGCGACGAGGCCTACCTGGGCGTGCTGGTGGACGATCTCATTACCCACGG
CACCACCGAGCCGTATCGCATGTTCACCAGCCGCGCCGAATACCGCTTGCAGCTGCGCGAGGACAATGCCGATGCGCGGC
TGACCGGCGTCGGGCGTGCGATGGGCCTGGTGGACGACGCGCGCTGGGCGCGCTTTGCGGCCAAGCAGGAGGCCGTGCAA
CGCGAAACGACGCGGTTGTCTGCACTGTGGGCCACACCGGGCAATGCGCTGGGCCGCGAGGTGGCCGGCGCGCTGGGCGT
GACGGTCAGCCGCGAAACCAACGTGCTGGATCTGATCAAGCGCCCGGAGCTCACCTACGCCACCTTGATGCGGGTGCCGA
CCCTGGGCCCGGGCGTGGACGATGCGCAGGTAGCCGAGCAGGTCGAGATCAGCGTCAAGTACGCCGGTTATCTGGATCGC
CAGCGCGACGATATCGCGCGTCAGCAACGCCACGAAACCACGCCGATCCCGGAAGGGTTCGACTACGCCAGCGTGCGTGG
TCTGTCGATCGAAGTGCAACAGAAACTCGAGCGCGTGCGTCCCCAGCACATCGGCCAGGCACAACGGATTCCCGGCATGA
CGCCGGCAGCGATCTCGCTGCTGCTGGTGCATCTGGAGCGCGCGCGGCGCAGCCAGGTGGCGTGA

Upstream 100 bases:

>100_bases
TGTGATTTTCATCACAATTTATAGCGAACGAGTGACCTCGCCCGCCCTTCAGCCGATACTTTCGCGGCCGTTTTCCTTTT
CCCGCTCCTGGTCCACGCCC

Downstream 100 bases:

>100_bases
TCGACGCGACGATCGCTGCCCGTCGGCAGCGATCGCCGGGCCATCCATCCCTCTGAAGGCAGCAGTGAGCGCGCCAGTCA
TCGCGAAACGATGACGTGTG

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MSDSFYRYDVIVIGGGHAGTEAALASARTGARTLLLTHNIETVGAMSCNPAIGGIGKGHLVKEIDGLGGAMARAADLAGI
QWRTLNASKGPAVRATRCQADRNLYRTAIRCIVEAQPNLTVFQAAVDDLIIHNGTSEADSVRGVITQTGLRFQAPSVVLT
AGTFLAGKIHVGETQYAAGRMGDPPATTLAARLRERPFAIDRLKTGTPPRIDGRTLDYGVMAEQPGDDPLPVMSFMGQVS
DHPRQVSCWITQTTEQTHEIIRNALHRSPLYSGQIEGIGPRYCPSIEDKVVRFAEKTSHQIFVEPEGLEVAEIYPNGIST
SLPFDVQLALVRSIHGFANAHITRPGYAIEYDFFDPRGLKASLETKAVGGLFFAGQINGTTGYEEAAAQGLLAGLNAARH
VQGLPAWSPRRDEAYLGVLVDDLITHGTTEPYRMFTSRAEYRLQLREDNADARLTGVGRAMGLVDDARWARFAAKQEAVQ
RETTRLSALWATPGNALGREVAGALGVTVSRETNVLDLIKRPELTYATLMRVPTLGPGVDDAQVAEQVEISVKYAGYLDR
QRDDIARQQRHETTPIPEGFDYASVRGLSIEVQQKLERVRPQHIGQAQRIPGMTPAAISLLLVHLERARRSQVA

Sequences:

>Translated_634_residues
MSDSFYRYDVIVIGGGHAGTEAALASARTGARTLLLTHNIETVGAMSCNPAIGGIGKGHLVKEIDGLGGAMARAADLAGI
QWRTLNASKGPAVRATRCQADRNLYRTAIRCIVEAQPNLTVFQAAVDDLIIHNGTSEADSVRGVITQTGLRFQAPSVVLT
AGTFLAGKIHVGETQYAAGRMGDPPATTLAARLRERPFAIDRLKTGTPPRIDGRTLDYGVMAEQPGDDPLPVMSFMGQVS
DHPRQVSCWITQTTEQTHEIIRNALHRSPLYSGQIEGIGPRYCPSIEDKVVRFAEKTSHQIFVEPEGLEVAEIYPNGIST
SLPFDVQLALVRSIHGFANAHITRPGYAIEYDFFDPRGLKASLETKAVGGLFFAGQINGTTGYEEAAAQGLLAGLNAARH
VQGLPAWSPRRDEAYLGVLVDDLITHGTTEPYRMFTSRAEYRLQLREDNADARLTGVGRAMGLVDDARWARFAAKQEAVQ
RETTRLSALWATPGNALGREVAGALGVTVSRETNVLDLIKRPELTYATLMRVPTLGPGVDDAQVAEQVEISVKYAGYLDR
QRDDIARQQRHETTPIPEGFDYASVRGLSIEVQQKLERVRPQHIGQAQRIPGMTPAAISLLLVHLERARRSQVA
>Mature_633_residues
SDSFYRYDVIVIGGGHAGTEAALASARTGARTLLLTHNIETVGAMSCNPAIGGIGKGHLVKEIDGLGGAMARAADLAGIQ
WRTLNASKGPAVRATRCQADRNLYRTAIRCIVEAQPNLTVFQAAVDDLIIHNGTSEADSVRGVITQTGLRFQAPSVVLTA
GTFLAGKIHVGETQYAAGRMGDPPATTLAARLRERPFAIDRLKTGTPPRIDGRTLDYGVMAEQPGDDPLPVMSFMGQVSD
HPRQVSCWITQTTEQTHEIIRNALHRSPLYSGQIEGIGPRYCPSIEDKVVRFAEKTSHQIFVEPEGLEVAEIYPNGISTS
LPFDVQLALVRSIHGFANAHITRPGYAIEYDFFDPRGLKASLETKAVGGLFFAGQINGTTGYEEAAAQGLLAGLNAARHV
QGLPAWSPRRDEAYLGVLVDDLITHGTTEPYRMFTSRAEYRLQLREDNADARLTGVGRAMGLVDDARWARFAAKQEAVQR
ETTRLSALWATPGNALGREVAGALGVTVSRETNVLDLIKRPELTYATLMRVPTLGPGVDDAQVAEQVEISVKYAGYLDRQ
RDDIARQQRHETTPIPEGFDYASVRGLSIEVQQKLERVRPQHIGQAQRIPGMTPAAISLLLVHLERARRSQVA

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 [H]

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family [H]

Homologues:

Organism=Homo sapiens, GI74024895, Length=641, Percent_Identity=43.6817472698908, Blast_Score=480, Evalue=1e-135,
Organism=Homo sapiens, GI19882217, Length=666, Percent_Identity=42.042042042042, Blast_Score=466, Evalue=1e-131,
Organism=Homo sapiens, GI183227703, Length=681, Percent_Identity=41.1160058737151, Blast_Score=460, Evalue=1e-129,
Organism=Escherichia coli, GI2367273, Length=620, Percent_Identity=64.5161290322581, Blast_Score=818, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17534255, Length=624, Percent_Identity=39.5833333333333, Blast_Score=448, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321202, Length=644, Percent_Identity=44.0993788819876, Blast_Score=495, Evalue=1e-141,
Organism=Drosophila melanogaster, GI24658174, Length=632, Percent_Identity=44.9367088607595, Blast_Score=485, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595 [H]

Pfam domain/function: PF01134 GIDA [H]

EC number: NA

Molecular weight: Translated: 68892; Mature: 68761

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS01280 GIDA_1 ; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSFYRYDVIVIGGGHAGTEAALASARTGARTLLLTHNIETVGAMSCNPAIGGIGKGHL
CCCCEEEEEEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCEEECCCCCCCCCCCCCCCH
VKEIDGLGGAMARAADLAGIQWRTLNASKGPAVRATRCQADRNLYRTAIRCIVEAQPNLT
HHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCE
VFQAAVDDLIIHNGTSEADSVRGVITQTGLRFQAPSVVLTAGTFLAGKIHVGETQYAAGR
EHHHHHHHHEEECCCCCHHHHHHHHHHCCCEEECCCEEEEECCEEEEEEEECCCHHCCCC
MGDPPATTLAARLRERPFAIDRLKTGTPPRIDGRTLDYGVMAEQPGDDPLPVMSFMGQVS
CCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEECCCEEECCCCCCCCHHHHHHHHHC
DHPRQVSCWITQTTEQTHEIIRNALHRSPLYSGQIEGIGPRYCPSIEDKVVRFAEKTSHQ
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCE
IFVEPEGLEVAEIYPNGISTSLPFDVQLALVRSIHGFANAHITRPGYAIEYDFFDPRGLK
EEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCEEEEECCCCCCCCC
ASLETKAVGGLFFAGQINGTTGYEEAAAQGLLAGLNAARHVQGLPAWSPRRDEAYLGVLV
CCCCHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
DDLITHGTTEPYRMFTSRAEYRLQLREDNADARLTGVGRAMGLVDDARWARFAAKQEAVQ
HHHHHCCCCCHHHHHHCCCEEEEEEECCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHH
RETTRLSALWATPGNALGREVAGALGVTVSRETNVLDLIKRPELTYATLMRVPTLGPGVD
HHHHHEEEEECCCCHHHHHHHHHHHCEEECCCCCHHHHHCCCCCHHHHHHHCCCCCCCCC
DAQVAEQVEISVKYAGYLDRQRDDIARQQRHETTPIPEGFDYASVRGLSIEVQQKLERVR
HHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHHEECCEEHHHHHHHHHC
PQHIGQAQRIPGMTPAAISLLLVHLERARRSQVA
HHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDSFYRYDVIVIGGGHAGTEAALASARTGARTLLLTHNIETVGAMSCNPAIGGIGKGHL
CCCEEEEEEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCEEECCCCCCCCCCCCCCCH
VKEIDGLGGAMARAADLAGIQWRTLNASKGPAVRATRCQADRNLYRTAIRCIVEAQPNLT
HHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCE
VFQAAVDDLIIHNGTSEADSVRGVITQTGLRFQAPSVVLTAGTFLAGKIHVGETQYAAGR
EHHHHHHHHEEECCCCCHHHHHHHHHHCCCEEECCCEEEEECCEEEEEEEECCCHHCCCC
MGDPPATTLAARLRERPFAIDRLKTGTPPRIDGRTLDYGVMAEQPGDDPLPVMSFMGQVS
CCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEECCCEEECCCCCCCCHHHHHHHHHC
DHPRQVSCWITQTTEQTHEIIRNALHRSPLYSGQIEGIGPRYCPSIEDKVVRFAEKTSHQ
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCE
IFVEPEGLEVAEIYPNGISTSLPFDVQLALVRSIHGFANAHITRPGYAIEYDFFDPRGLK
EEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCEEEEECCCCCCCCC
ASLETKAVGGLFFAGQINGTTGYEEAAAQGLLAGLNAARHVQGLPAWSPRRDEAYLGVLV
CCCCHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
DDLITHGTTEPYRMFTSRAEYRLQLREDNADARLTGVGRAMGLVDDARWARFAAKQEAVQ
HHHHHCCCCCHHHHHHCCCEEEEEEECCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHH
RETTRLSALWATPGNALGREVAGALGVTVSRETNVLDLIKRPELTYATLMRVPTLGPGVD
HHHHHEEEEECCCCHHHHHHHHHHHCEEECCCCCHHHHHCCCCCHHHHHHHCCCCCCCCC
DAQVAEQVEISVKYAGYLDRQRDDIARQQRHETTPIPEGFDYASVRGLSIEVQQKLERVR
HHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHHEECCEEHHHHHHHHHC
PQHIGQAQRIPGMTPAAISLLLVHLERARRSQVA
HHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]