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The map label for this gene is ydfG [C]

Identifier: 78045812

GI number: 78045812

Start: 297472

End: 298401

Strand: Reverse

Name: ydfG [C]

Synonym: XCV0256

Alternate gene names: 78045812

Gene position: 298401-297472 (Counterclockwise)

Preceding gene: 78045813

Following gene: 78045807

Centisome position: 5.76

GC content: 67.31

Gene sequence:

>930_bases
ATGAGCGGCTGGACGCTAGCCGATCTGCCATCGCAGCGGGGACGAGTGGCCATCGTCACCGGCGCCAGTCCCGGCGGACT
GGGCTACGAAACCGCGCTGGCCCTGGCCGGTGCCGGCGCCCATGTCGTGCTGACCGCACGCAACCCCGACAGGGGCGAAG
CGGCACGCTGGGCGCTGCTTGCCCGCCATTCGGAGGCCGAGGTGCGTGTGGAGGCGCTTGACTTGGCAAGTTTGGCGTCG
GTTCGCGCATTCGCCAAGCGGCTGACCACGCGCCATGCTGCGGTGGATCTGCTGATCAACAACGCCGGCGTGATGGCGCC
CCCGCAACGGCAAACCACCGCCGACGGGATGGAGTTGCAACTGGGCAGCAATTACCTGGGACATTTTGCGCTGACCGCGC
AGGTACTTCCTTTGCTGCGTGCTGCGTCGGCACCGCGTGTGGTCAACTTGTCGAGCCTGGCGCATCGACAGGCGCGCATC
GATTTCGACGATCTGCAGAGCGAACGCCCATACCGTCCGTGGAAAGCCTATGGGCAATCCAAGTTGGCAATGCTGATGTT
CAGCCTGGAATTGCAGCGCCGCAGCAACACGCATGGCTGGGGCGTGCGTGCGATCGCCGCGCACCCGGGAATCGCACGGA
CCGCCTTGATCGCCAACGGGCCGGACGGCGCAGGCCGACGCAGCGCGAGCGGCGTGGCCACCGGGCTGTTCACCCGCTGC
ATCGGCCATTCGGCAAGCGCGGGCGCACGACCGACGCTGTATGCGGCGACGTCTCCGCAGGCACAGGCCGGGGGCTATTA
CGGACCAAACGGCCTGTTCGAGCTGAAGGGCGATCCGGCGCCTGCCAAGATCGCCCACCAGGCGCATGACCAGCAGGTGG
CAGCACGCTTGTGGGATACCGCGTGTGCGCTGACGGGCGTGGCGTTCTGA

Upstream 100 bases:

>100_bases
CGCTGGCCATCCCGCAGATGGGCGAACGGGTGAACGCGCACCGCCCGGACACCGATCAACGCTGGTGGCGCACGCTGCCC
GACACTCTGGTACTTGCGTG

Downstream 100 bases:

>100_bases
TGGCGCCCTGATGAAGCCGGCCACGCAGTTTGACTTGGTCTCTGCACTGCGCTGCGCAAGTGAAGCCGTCGCAGCGGCTG
CGCTTGCGGAGACGTTGCGA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSGWTLADLPSQRGRVAIVTGASPGGLGYETALALAGAGAHVVLTARNPDRGEAARWALLARHSEAEVRVEALDLASLAS
VRAFAKRLTTRHAAVDLLINNAGVMAPPQRQTTADGMELQLGSNYLGHFALTAQVLPLLRAASAPRVVNLSSLAHRQARI
DFDDLQSERPYRPWKAYGQSKLAMLMFSLELQRRSNTHGWGVRAIAAHPGIARTALIANGPDGAGRRSASGVATGLFTRC
IGHSASAGARPTLYAATSPQAQAGGYYGPNGLFELKGDPAPAKIAHQAHDQQVAARLWDTACALTGVAF

Sequences:

>Translated_309_residues
MSGWTLADLPSQRGRVAIVTGASPGGLGYETALALAGAGAHVVLTARNPDRGEAARWALLARHSEAEVRVEALDLASLAS
VRAFAKRLTTRHAAVDLLINNAGVMAPPQRQTTADGMELQLGSNYLGHFALTAQVLPLLRAASAPRVVNLSSLAHRQARI
DFDDLQSERPYRPWKAYGQSKLAMLMFSLELQRRSNTHGWGVRAIAAHPGIARTALIANGPDGAGRRSASGVATGLFTRC
IGHSASAGARPTLYAATSPQAQAGGYYGPNGLFELKGDPAPAKIAHQAHDQQVAARLWDTACALTGVAF
>Mature_308_residues
SGWTLADLPSQRGRVAIVTGASPGGLGYETALALAGAGAHVVLTARNPDRGEAARWALLARHSEAEVRVEALDLASLASV
RAFAKRLTTRHAAVDLLINNAGVMAPPQRQTTADGMELQLGSNYLGHFALTAQVLPLLRAASAPRVVNLSSLAHRQARID
FDDLQSERPYRPWKAYGQSKLAMLMFSLELQRRSNTHGWGVRAIAAHPGIARTALIANGPDGAGRRSASGVATGLFTRCI
GHSASAGARPTLYAATSPQAQAGGYYGPNGLFELKGDPAPAKIAHQAHDQQVAARLWDTACALTGVAF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=296, Percent_Identity=40.8783783783784, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI193804850, Length=304, Percent_Identity=35.1973684210526, Blast_Score=161, Evalue=7e-40,
Organism=Homo sapiens, GI186928839, Length=296, Percent_Identity=36.4864864864865, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI166795268, Length=296, Percent_Identity=36.8243243243243, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI19923931, Length=259, Percent_Identity=41.6988416988417, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI10190746, Length=313, Percent_Identity=34.5047923322684, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI7706523, Length=297, Percent_Identity=35.016835016835, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI146231950, Length=300, Percent_Identity=36.6666666666667, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI7705421, Length=233, Percent_Identity=30.4721030042918, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI13375997, Length=148, Percent_Identity=30.4054054054054, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193207620, Length=305, Percent_Identity=31.4754098360656, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17532791, Length=303, Percent_Identity=28.0528052805281, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17558006, Length=325, Percent_Identity=28.3076923076923, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17532805, Length=298, Percent_Identity=29.8657718120805, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71992402, Length=300, Percent_Identity=29.3333333333333, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17535059, Length=296, Percent_Identity=29.7297297297297, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17505416, Length=215, Percent_Identity=32.093023255814, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32565532, Length=206, Percent_Identity=31.0679611650485, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI72001364, Length=273, Percent_Identity=29.6703296703297, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115533172, Length=287, Percent_Identity=25.7839721254355, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI115533174, Length=287, Percent_Identity=25.4355400696864, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6324820, Length=297, Percent_Identity=26.9360269360269, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6324148, Length=324, Percent_Identity=24.6913580246914, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=207, Percent_Identity=26.5700483091787, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573296, Length=269, Percent_Identity=39.0334572490706, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI45554248, Length=257, Percent_Identity=41.2451361867704, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24640117, Length=257, Percent_Identity=41.2451361867704, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24586328, Length=304, Percent_Identity=37.171052631579, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI22024069, Length=316, Percent_Identity=35.4430379746835, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI19921754, Length=309, Percent_Identity=35.2750809061489, Blast_Score=154, Evalue=7e-38,
Organism=Drosophila melanogaster, GI161076371, Length=300, Percent_Identity=36, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24656154, Length=269, Percent_Identity=33.8289962825279, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19922628, Length=269, Percent_Identity=33.8289962825279, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24647946, Length=297, Percent_Identity=27.9461279461279, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI45553409, Length=296, Percent_Identity=28.0405405405405, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24647948, Length=296, Percent_Identity=28.0405405405405, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI20129347, Length=205, Percent_Identity=36.5853658536585, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24647931, Length=324, Percent_Identity=29.6296296296296, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21358495, Length=215, Percent_Identity=32.093023255814, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32520; Mature: 32389

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGWTLADLPSQRGRVAIVTGASPGGLGYETALALAGAGAHVVLTARNPDRGEAARWALL
CCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHH
ARHSEAEVRVEALDLASLASVRAFAKRLTTRHAAVDLLINNAGVMAPPQRQTTADGMELQ
HCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCEEEE
LGSNYLGHFALTAQVLPLLRAASAPRVVNLSSLAHRQARIDFDDLQSERPYRPWKAYGQS
ECCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCHHHHCCCCCCCHHHHHCCH
KLAMLMFSLELQRRSNTHGWGVRAIAAHPGIARTALIANGPDGAGRRSASGVATGLFTRC
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHH
IGHSASAGARPTLYAATSPQAQAGGYYGPNGLFELKGDPAPAKIAHQAHDQQVAARLWDT
HCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ACALTGVAF
HHHHHHCCC
>Mature Secondary Structure 
SGWTLADLPSQRGRVAIVTGASPGGLGYETALALAGAGAHVVLTARNPDRGEAARWALL
CCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHH
ARHSEAEVRVEALDLASLASVRAFAKRLTTRHAAVDLLINNAGVMAPPQRQTTADGMELQ
HCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCEEEE
LGSNYLGHFALTAQVLPLLRAASAPRVVNLSSLAHRQARIDFDDLQSERPYRPWKAYGQS
ECCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCHHHHCCCCCCCHHHHHCCH
KLAMLMFSLELQRRSNTHGWGVRAIAAHPGIARTALIANGPDGAGRRSASGVATGLFTRC
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHH
IGHSASAGARPTLYAATSPQAQAGGYYGPNGLFELKGDPAPAKIAHQAHDQQVAARLWDT
HCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ACALTGVAF
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]