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The map label for this gene is uppP [H]

Identifier: 78045743

GI number: 78045743

Start: 223058

End: 223855

Strand: Reverse

Name: uppP [H]

Synonym: XCV0187

Alternate gene names: 78045743

Gene position: 223855-223058 (Counterclockwise)

Preceding gene: 78045751

Following gene: 78045742

Centisome position: 4.32

GC content: 64.91

Gene sequence:

>798_bases
ATGTCCGATCTGATTTCCGCCCTGTTGTTGGGCATTCTCGAAGGCCTCACCGAATTCCTGCCGATCTCCAGCACCGGCCA
CCTGTTGATCGCCGAACAATGGCTCGGACGCCGTTCTGACTTCTTCAATATCGTCATCCAGGCCGGCGCGATCCTGGCCA
TCTGCCTGGCGCTGCGGCAGCGCCTGTGGAGCCTGGCCACCGGCCTGGGCGAGCGCGCCAACCGCGACTACGTGCTCAAG
GTCGGCGTGGCCTTCCTGGTCACCGCGGTGGTCGGGCTGATCGTGCGCAAGGCCGGCTGGCAATTGCCCGAAACGCTCCA
ACCGGTCGCCTGGGCGTTGCTGATCGGCGGGGTATGGATGCTGGTGGCCGAACACTTCGCCGGCAAGCTGCCCGAGCGCG
ATGTGGTGACCTGGAAGGTAGCCATCGCCGTAGGCCTGGCGCAGGTCGTGGCCGGTGTTTTTCCCGGAACGTCGCGCTCG
GCCTCGACGATCTTCATCGCGATGCTGCTGGGCCTGAGCAAGCGCTCGGCAGCGGCGGATTTCGTGTTCATGGTGGGCAT
TCCGACCATGTTTGCGGCCAGCGGCTACGCGCTGCTGGAGATGTACAAGGAAGGCGGTTTCGGCACCGAAAACTGGACCG
ACGTGGCGGTGGCCTTCGTGGCGGCGACCATCACCGGCTTTGTGGTGGTGAAGTGGCTGCTGGGCTATATCAAGAAGCAC
CGTTTCACGGTGTTTGCGGTGTATCGCATGCTGCTGGGCGCCGCCCTGCTGCTGTGGCTGCCGGCGGCGGCGGGCTGA

Upstream 100 bases:

>100_bases
GCATCGCACCATGAAAGTGCAAAGCGCAAATTAGAACGCACCGATATGGTGCATGCCGCAATGCACTATCCTGGCGCCTC
CCTCACCCCTGCCCAGTCCG

Downstream 100 bases:

>100_bases
CATTCCACCGCCCCGGCCTGCACGTCGTGATGGCTGCGACGTGCAGGCCGGGCGCACACAAACGCGCTGGGCACTGCCGC
GTCCGCGCGCTGCCAGCCGA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQRLWSLATGLGERANRDYVLK
VGVAFLVTAVVGLIVRKAGWQLPETLQPVAWALLIGGVWMLVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRS
ASTIFIAMLLGLSKRSAAADFVFMVGIPTMFAASGYALLEMYKEGGFGTENWTDVAVAFVAATITGFVVVKWLLGYIKKH
RFTVFAVYRMLLGAALLLWLPAAAG

Sequences:

>Translated_265_residues
MSDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQRLWSLATGLGERANRDYVLK
VGVAFLVTAVVGLIVRKAGWQLPETLQPVAWALLIGGVWMLVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRS
ASTIFIAMLLGLSKRSAAADFVFMVGIPTMFAASGYALLEMYKEGGFGTENWTDVAVAFVAATITGFVVVKWLLGYIKKH
RFTVFAVYRMLLGAALLLWLPAAAG
>Mature_264_residues
SDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQRLWSLATGLGERANRDYVLKV
GVAFLVTAVVGLIVRKAGWQLPETLQPVAWALLIGGVWMLVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRSA
STIFIAMLLGLSKRSAAADFVFMVGIPTMFAASGYALLEMYKEGGFGTENWTDVAVAFVAATITGFVVVKWLLGYIKKHR
FTVFAVYRMLLGAALLLWLPAAAG

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin [H]

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family [H]

Homologues:

Organism=Escherichia coli, GI1789437, Length=271, Percent_Identity=35.0553505535055, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003824 [H]

Pfam domain/function: PF02673 BacA [H]

EC number: =3.6.1.27 [H]

Molecular weight: Translated: 28524; Mature: 28393

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQ
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RLWSLATGLGERANRDYVLKVGVAFLVTAVVGLIVRKAGWQLPETLQPVAWALLIGGVWM
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRSASTIFIAMLLGLSKRSAAAD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHH
FVFMVGIPTMFAASGYALLEMYKEGGFGTENWTDVAVAFVAATITGFVVVKWLLGYIKKH
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFTVFAVYRMLLGAALLLWLPAAAG
HHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]