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The map label for this gene is cbbFC [H]

Identifier: 78045654

GI number: 78045654

Start: 114233

End: 115288

Strand: Reverse

Name: cbbFC [H]

Synonym: XCV0098

Alternate gene names: 78045654

Gene position: 115288-114233 (Counterclockwise)

Preceding gene: 78045655

Following gene: 78045653

Centisome position: 2.23

GC content: 64.58

Gene sequence:

>1056_bases
ATGGCGACAATGGCGGCCCACTTCCTACACAGGCTGCCCGTTCCCATGTCGCGTCCCTCGCTGACCCGCTTCCTGATCGA
AGAGCAACACGCCGGCCGTATCGATGCGGAATTGCGCCAGCTGATCACCATCGTCTCGCGCGCCTGCAAGCGCATCTCCA
TCGCCGTGAGCAAGGGCACCCTGGGCGGCGTGCTCGGCGATGCCGGCACCGGCAACGTGCAGGGCGAAGCACAGAAAAAG
CTCGATGTGCTCAGCAACGACATCCTGCTCGAAGCCAACGCCTGGGGCGGCCATCTGGCCGCGTGCGCGTCCGAAGAAAT
GGACCACAGCCAGCCGGTGCCCGACCAATACCCCAGCGGCGATTTCCTGCTGTTGTTCGATCCCTTGGACGGCAGCTCCA
ATATCGACGTCAATGTCTCGGTGGGCACGATCTTCTCGGTATTGCGCGCGCCCAAGGGCACCGAAAAGCCGGGCGACGAG
CACTTCCTGCAGCCGGGCACCCAACAGGTCGCCGCCGGCTACTGCATCTACGGCCCCAGCACCATGCTGGTGCTCACGCT
GGGCCACGGCACCCACGCCTTCACCCTGGAGCGCGAAGAAGGCAGCTTCCTGCTGACCCAGGCCAACATGCGCGTGCCCG
AAGACACCGCCGAATACGCCATCAACATGTCCAACCAACGCCACTGGGAACCGGCGATGCAGGCCTACGTGGGCGACCTG
CTGGCCGGCAAGGACGGCGCGCGCGGCAAGGACTTCAACATGCGCTGGATCGCCAGCATGGTCGCCGACGTGCACCGCAT
CCTCACCCGCGGCGGCATCTTCATCTACCCGTGGGACAAAAAAGACCCGAGCAAGCCGGGCAAGCTGCGCCTGATGTACG
AAGCCAACCCGATGAGCATGCTGGTGGAACAGGCCGGCGGCGCGGCAACCACCGGGCGCGAACGCATTCTCGACATCCAG
CCGACACAGCTGCACCAGCGCGTACCGGTGTTCCTGGGCTCGAAGAACGAAGTGGCCGAAGCGACGCGATATCACCTGGA
TGCCGATAAGGCGTAA

Upstream 100 bases:

>100_bases
TGGTGTACAGCGAACGCCGGCCACATAAGGTTCAAGGGGTGCACTCCTGAAGTCGCTGCAGAGCAGAACGCGCACCCGAT
GATCGAAATCTAACGCCGCA

Downstream 100 bases:

>100_bases
GGCAGCGGGTGCAGCTTGCAAGGCACGCAAACTGGATTCCACAAGACACCCGCCTAGTGCGGGTGTCTTGGTTCATGGCG
CCCGCTGATTGCAGCGCTCA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MATMAAHFLHRLPVPMSRPSLTRFLIEEQHAGRIDAELRQLITIVSRACKRISIAVSKGTLGGVLGDAGTGNVQGEAQKK
LDVLSNDILLEANAWGGHLAACASEEMDHSQPVPDQYPSGDFLLLFDPLDGSSNIDVNVSVGTIFSVLRAPKGTEKPGDE
HFLQPGTQQVAAGYCIYGPSTMLVLTLGHGTHAFTLEREEGSFLLTQANMRVPEDTAEYAINMSNQRHWEPAMQAYVGDL
LAGKDGARGKDFNMRWIASMVADVHRILTRGGIFIYPWDKKDPSKPGKLRLMYEANPMSMLVEQAGGAATTGRERILDIQ
PTQLHQRVPVFLGSKNEVAEATRYHLDADKA

Sequences:

>Translated_351_residues
MATMAAHFLHRLPVPMSRPSLTRFLIEEQHAGRIDAELRQLITIVSRACKRISIAVSKGTLGGVLGDAGTGNVQGEAQKK
LDVLSNDILLEANAWGGHLAACASEEMDHSQPVPDQYPSGDFLLLFDPLDGSSNIDVNVSVGTIFSVLRAPKGTEKPGDE
HFLQPGTQQVAAGYCIYGPSTMLVLTLGHGTHAFTLEREEGSFLLTQANMRVPEDTAEYAINMSNQRHWEPAMQAYVGDL
LAGKDGARGKDFNMRWIASMVADVHRILTRGGIFIYPWDKKDPSKPGKLRLMYEANPMSMLVEQAGGAATTGRERILDIQ
PTQLHQRVPVFLGSKNEVAEATRYHLDADKA
>Mature_350_residues
ATMAAHFLHRLPVPMSRPSLTRFLIEEQHAGRIDAELRQLITIVSRACKRISIAVSKGTLGGVLGDAGTGNVQGEAQKKL
DVLSNDILLEANAWGGHLAACASEEMDHSQPVPDQYPSGDFLLLFDPLDGSSNIDVNVSVGTIFSVLRAPKGTEKPGDEH
FLQPGTQQVAAGYCIYGPSTMLVLTLGHGTHAFTLEREEGSFLLTQANMRVPEDTAEYAINMSNQRHWEPAMQAYVGDLL
AGKDGARGKDFNMRWIASMVADVHRILTRGGIFIYPWDKKDPSKPGKLRLMYEANPMSMLVEQAGGAATTGRERILDIQP
TQLHQRVPVFLGSKNEVAEATRYHLDADKA

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=329, Percent_Identity=44.3768996960486, Blast_Score=261, Evalue=5e-70,
Organism=Homo sapiens, GI16579888, Length=329, Percent_Identity=44.3768996960486, Blast_Score=261, Evalue=5e-70,
Organism=Homo sapiens, GI22907028, Length=330, Percent_Identity=39.3939393939394, Blast_Score=233, Evalue=2e-61,
Organism=Escherichia coli, GI1790679, Length=328, Percent_Identity=44.8170731707317, Blast_Score=259, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17508131, Length=329, Percent_Identity=44.9848024316109, Blast_Score=259, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6323409, Length=322, Percent_Identity=40.3726708074534, Blast_Score=230, Evalue=3e-61,
Organism=Drosophila melanogaster, GI45550998, Length=327, Percent_Identity=45.565749235474, Blast_Score=261, Evalue=6e-70,
Organism=Drosophila melanogaster, GI19921562, Length=327, Percent_Identity=45.565749235474, Blast_Score=261, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 38358; Mature: 38227

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATMAAHFLHRLPVPMSRPSLTRFLIEEQHAGRIDAELRQLITIVSRACKRISIAVSKGT
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEECCC
LGGVLGDAGTGNVQGEAQKKLDVLSNDILLEANAWGGHLAACASEEMDHSQPVPDQYPSG
CCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCC
DFLLLFDPLDGSSNIDVNVSVGTIFSVLRAPKGTEKPGDEHFLQPGTQQVAAGYCIYGPS
CEEEEEECCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHCCEEEECCC
TMLVLTLGHGTHAFTLEREEGSFLLTQANMRVPEDTAEYAINMSNQRHWEPAMQAYVGDL
EEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCHHHHEEECCCCCCCHHHHHHHHHHH
LAGKDGARGKDFNMRWIASMVADVHRILTRGGIFIYPWDKKDPSKPGKLRLMYEANPMSM
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCHHHH
LVEQAGGAATTGRERILDIQPTQLHQRVPVFLGSKNEVAEATRYHLDADKA
HHHHCCCCCCCCCCEEEECCHHHHHCCCCEEECCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ATMAAHFLHRLPVPMSRPSLTRFLIEEQHAGRIDAELRQLITIVSRACKRISIAVSKGT
CHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEECCC
LGGVLGDAGTGNVQGEAQKKLDVLSNDILLEANAWGGHLAACASEEMDHSQPVPDQYPSG
CCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCC
DFLLLFDPLDGSSNIDVNVSVGTIFSVLRAPKGTEKPGDEHFLQPGTQQVAAGYCIYGPS
CEEEEEECCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHCCEEEECCC
TMLVLTLGHGTHAFTLEREEGSFLLTQANMRVPEDTAEYAINMSNQRHWEPAMQAYVGDL
EEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCHHHHEEECCCCCCCHHHHHHHHHHH
LAGKDGARGKDFNMRWIASMVADVHRILTRGGIFIYPWDKKDPSKPGKLRLMYEANPMSM
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCHHHH
LVEQAGGAATTGRERILDIQPTQLHQRVPVFLGSKNEVAEATRYHLDADKA
HHHHCCCCCCCCCCEEEECCHHHHHCCCCEEECCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA