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The map label for this gene is pmbA [C]

Identifier: 78045647

GI number: 78045647

Start: 106447

End: 107781

Strand: Reverse

Name: pmbA [C]

Synonym: XCV0091

Alternate gene names: 78045647

Gene position: 107781-106447 (Counterclockwise)

Preceding gene: 78045648

Following gene: 78045646

Centisome position: 2.08

GC content: 63.07

Gene sequence:

>1335_bases
ATGAGCATCCTTACCGAAGCGCAGGCCAAGGCCATCCTGGACAAGGTCATCAAGCTGTCCAAGGCCGACGAGTGCACCGC
CACGCTCACCGGCTCGATCGACGGCAATATCCGTTTTGCGCTCAACAACGTGTCCACCAGCGGCATTGTCGACAACACCG
ACCTGCAGGTGCAGGTGGCGTTCGGCAAGCGCGTGGGCGTTGCCACCATCAACGCGTTCGACGACGCCTCGCTGGAGCGC
GTGGTGCGCCGTGCCGAAGACCTCGCACGGCTGGCGCCGGAAAACCCGGAATTCATGCCGGCGGTCGACAAGCAGACCTA
CAGGCCCAGCCCAACCTTCAGCGAATCCACGGCAGCGGTCGATCCGGCGTTCCGCGCGCAGGTGGCGGCCGACTCGATCG
CCCCATGCAAGGGCAAGGGGCTGATCGCCGCAGGCTTCCTCGAAGACGGCCAGAGCTTTACCGCATTCGCCAACAGCAAG
GGCAACTTCGGCTATCAGCGCGGTGCGCGCTTCGACTACACCTGCACCGTGCGCACCGAAGATGGTCGCGGCTCGGGCTG
GGTGGGCCGCAATTTGAAGGATGCTGCCGACTTCAAGGCCGAGCAGGACATCCGCATCGCGATGCGCAAGGCCAGCGATT
CGGCCGAAGCCAAGGCGTTGGAGCCGGGCAAATACACGGTGATCCTGGAGCCGGCGGCGGCCGCAGGCCTGATCTCGTTC
ATGATGAATTTCTTCGATGCGCGCATGGCCGATGAGGGGCGCAGCTTCCTGTCCAAGAAAGGTGGCGGCAACAAGCTCGG
CGAACAGGTCTACGACCCGCGCGTGAACATCACCGCCGACCCGTGGGACCCGCGTGCGGCAGTGATGCCGTGGGACGAGG
AAGGCCTGCCGCGCGAGAAGATGTCCATCGTGGAAAACGGCAAGATCGCCAACCTGCAGTATTCCCGCTTCTGGGCGCAG
AAAAACGGCAAGCGTGCGGTCGGCGAGCCGGGCAACCTGCTGATGGCCGGCGGCGACAAGAACATCGCCGAGCTGGTGCG
TGGTACCGAGAAGGGCATCCTGGTCACGCGCACCTGGTACATCCGCATGGTCGACCCGCAGACCGTGCTGCTGACCGGGC
TCACCCGCGACGGCACGTTCTACATCGAGAACGGCCAGATCAAATACCCGGTGAAGAATTTCCGCTTCAACGAATCGCCG
GTGATCATGCTCAATAACATCGATGAGTTGGGCAAGCCGGTGCGCGTGGCTGGCGATGAATCCAACTTCGTGATGATGAT
TCCGCCGATGCGGCTGCGGGACTTTACGTTTACTTCGTTGTCGGATGCGGTGTGA

Upstream 100 bases:

>100_bases
GCCAGGTCTCGGCGGTCTCGCACGGTTCGTCCACCGCCCGCTTCGATGGCATCAATGTCATCAGCACCGCCCGCTCGCTC
GGCTGACAGGAGAAACCCAC

Downstream 100 bases:

>100_bases
GTAGGAGCCGGGAATCGGGAGTCGGGATTCGAGAATGGGAGAGCACAGCAGGCTCTCTGCATCCTGATACTTTTCCTGCA
CCTTCCGTTTCCGGTCTACG

Product: putative modulator of DNA gyrase

Products: NA

Alternate protein names: PmbA Protein; TldD/PmbA Family Protein; Zn-Dependent Protease; Peptidase PmbA; Modulator Of DNA Gyrase; Zinc-Dependent Protease TldD/PmbA Family; CalR5 Protein; TldD/PmbA Family; TldD Protein; Zinc-Dependent Protease; Modulator Of DNA Gyrase Protein; Protein PmbA; Zn-Dependent Protease-Like Protein; TldE-Like Protein; LOW QUALITY PROTEIN CalR5 Protein; PmbA-Related Protein; Maturation Protein; DNA Gyrase Modulator Family Protein; Protein For Maturation Of Antibiotic MccB; TldE/PmbA-Like Protein; Protease PmbA; Modulator Of DNA Gyrase Protein TldD; Zinc Protease PmbA; Microcin-Processing Peptidase PmbA; Zn-Dependent Protease Modulator Of DNA Gyrase; Regulatory Protease

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSILTEAQAKAILDKVIKLSKADECTATLTGSIDGNIRFALNNVSTSGIVDNTDLQVQVAFGKRVGVATINAFDDASLER
VVRRAEDLARLAPENPEFMPAVDKQTYRPSPTFSESTAAVDPAFRAQVAADSIAPCKGKGLIAAGFLEDGQSFTAFANSK
GNFGYQRGARFDYTCTVRTEDGRGSGWVGRNLKDAADFKAEQDIRIAMRKASDSAEAKALEPGKYTVILEPAAAAGLISF
MMNFFDARMADEGRSFLSKKGGGNKLGEQVYDPRVNITADPWDPRAAVMPWDEEGLPREKMSIVENGKIANLQYSRFWAQ
KNGKRAVGEPGNLLMAGGDKNIAELVRGTEKGILVTRTWYIRMVDPQTVLLTGLTRDGTFYIENGQIKYPVKNFRFNESP
VIMLNNIDELGKPVRVAGDESNFVMMIPPMRLRDFTFTSLSDAV

Sequences:

>Translated_444_residues
MSILTEAQAKAILDKVIKLSKADECTATLTGSIDGNIRFALNNVSTSGIVDNTDLQVQVAFGKRVGVATINAFDDASLER
VVRRAEDLARLAPENPEFMPAVDKQTYRPSPTFSESTAAVDPAFRAQVAADSIAPCKGKGLIAAGFLEDGQSFTAFANSK
GNFGYQRGARFDYTCTVRTEDGRGSGWVGRNLKDAADFKAEQDIRIAMRKASDSAEAKALEPGKYTVILEPAAAAGLISF
MMNFFDARMADEGRSFLSKKGGGNKLGEQVYDPRVNITADPWDPRAAVMPWDEEGLPREKMSIVENGKIANLQYSRFWAQ
KNGKRAVGEPGNLLMAGGDKNIAELVRGTEKGILVTRTWYIRMVDPQTVLLTGLTRDGTFYIENGQIKYPVKNFRFNESP
VIMLNNIDELGKPVRVAGDESNFVMMIPPMRLRDFTFTSLSDAV
>Mature_443_residues
SILTEAQAKAILDKVIKLSKADECTATLTGSIDGNIRFALNNVSTSGIVDNTDLQVQVAFGKRVGVATINAFDDASLERV
VRRAEDLARLAPENPEFMPAVDKQTYRPSPTFSESTAAVDPAFRAQVAADSIAPCKGKGLIAAGFLEDGQSFTAFANSKG
NFGYQRGARFDYTCTVRTEDGRGSGWVGRNLKDAADFKAEQDIRIAMRKASDSAEAKALEPGKYTVILEPAAAAGLISFM
MNFFDARMADEGRSFLSKKGGGNKLGEQVYDPRVNITADPWDPRAAVMPWDEEGLPREKMSIVENGKIANLQYSRFWAQK
NGKRAVGEPGNLLMAGGDKNIAELVRGTEKGILVTRTWYIRMVDPQTVLLTGLTRDGTFYIENGQIKYPVKNFRFNESPV
IMLNNIDELGKPVRVAGDESNFVMMIPPMRLRDFTFTSLSDAV

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48589; Mature: 48457

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILTEAQAKAILDKVIKLSKADECTATLTGSIDGNIRFALNNVSTSGIVDNTDLQVQVA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCEEECCCEEEEEE
FGKRVGVATINAFDDASLERVVRRAEDLARLAPENPEFMPAVDKQTYRPSPTFSESTAAV
ECCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DPAFRAQVAADSIAPCKGKGLIAAGFLEDGQSFTAFANSKGNFGYQRGARFDYTCTVRTE
CHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEEEEEC
DGRGSGWVGRNLKDAADFKAEQDIRIAMRKASDSAEAKALEPGKYTVILEPAAAAGLISF
CCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCCCCCEEECCCCEEEEECCHHHHHHHHH
MMNFFDARMADEGRSFLSKKGGGNKLGEQVYDPRVNITADPWDPRAAVMPWDEEGLPREK
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCEEECCCCCCCCCHHH
MSIVENGKIANLQYSRFWAQKNGKRAVGEPGNLLMAGGDKNIAELVRGTEKGILVTRTWY
HHHHCCCCEEEEEHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHCCCCCCEEEEEEEE
IRMVDPQTVLLTGLTRDGTFYIENGQIKYPVKNFRFNESPVIMLNNIDELGKPVRVAGDE
EEEECCCEEEEEEECCCCEEEEECCEEEECHHHCCCCCCCEEEECCHHHHCCCEEEECCC
SNFVMMIPPMRLRDFTFTSLSDAV
CCEEEEECCCCCCCCEECHHHCCC
>Mature Secondary Structure 
SILTEAQAKAILDKVIKLSKADECTATLTGSIDGNIRFALNNVSTSGIVDNTDLQVQVA
CCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCEEECCCEEEEEE
FGKRVGVATINAFDDASLERVVRRAEDLARLAPENPEFMPAVDKQTYRPSPTFSESTAAV
ECCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DPAFRAQVAADSIAPCKGKGLIAAGFLEDGQSFTAFANSKGNFGYQRGARFDYTCTVRTE
CHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEEEEEC
DGRGSGWVGRNLKDAADFKAEQDIRIAMRKASDSAEAKALEPGKYTVILEPAAAAGLISF
CCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCCCCCEEECCCCEEEEECCHHHHHHHHH
MMNFFDARMADEGRSFLSKKGGGNKLGEQVYDPRVNITADPWDPRAAVMPWDEEGLPREK
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCEEECCCCCCCCCHHH
MSIVENGKIANLQYSRFWAQKNGKRAVGEPGNLLMAGGDKNIAELVRGTEKGILVTRTWY
HHHHCCCCEEEEEHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHCCCCCCEEEEEEEE
IRMVDPQTVLLTGLTRDGTFYIENGQIKYPVKNFRFNESPVIMLNNIDELGKPVRVAGDE
EEEECCCEEEEEEECCCCEEEEECCEEEECHHHCCCCCCCEEEECCHHHHCCCEEEECCC
SNFVMMIPPMRLRDFTFTSLSDAV
CCEEEEECCCCCCCCEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA