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The map label for this gene is prsA [H]

Identifier: 78045210

GI number: 78045210

Start: 168482

End: 169495

Strand: Direct

Name: prsA [H]

Synonym: CHY_0201

Alternate gene names: 78045210

Gene position: 168482-169495 (Clockwise)

Preceding gene: 78043233

Following gene: 78044362

Centisome position: 7.02

GC content: 39.94

Gene sequence:

>1014_bases
ATGAAAAAAATTACAAGAGTTGTTGCCGTACTTTTAACCTTTGTCCTGGCCTTAATCGTTGCGGGTTGTGGGGATTACGT
GGCCAAAGTGAATGGAAAAACTATTTCCAAAAAAGATTTCGACCGGCGGTTTGCCCAGGTACAGGCTGACATGAAGCTAA
GAGGAGTGGATTTAACCTCCACCGAGGGGCAGAAGATGCTTCAGAGCTTAAAGCAGCAGACTCTGGACCAGATGATCAAT
GAAATTCTAATTTCCGAGTATGGAAAGGAAAAGAAAATTGAACCGACAAAAGACGAAATTACCAATAAAATTAATGAAAT
TCGGGCCCAGTTCCCATCACCCCAGGATTTTGAAAAAGCTTTAAAAGACCGCAATATAACCGACAAAGATTTGCAAGAAA
TGGTTCGGGTGCAACTAATAAATGACAAAATTTACAACGAAGTAACCAAAGGGATTACCGTATCCGAACAGGAAGTTAAG
GAGTATTATGAAAAACATAAAAACGAGCCGGATTTTCAAACACCGGAGCAGCGGCAGGTAAGGCATATTTTAATTGCGGT
TAACGATGGAAATGCTCAAAACAATCCCCATTTTAACATCAATGTCAAAAGAACCGATGCGGAAGCCAAAAAGCTTGCCG
AGGAGTTAATAAAACAAATAAAAGCCGGAAAGGATTTTGCTACCCTGGCTAAAGAAAAATCCGATGATCCGGGAGTAAAA
GAAAATGGGGGGCAGTATACCTTCAGCCGGGGGGAGATGGTAAAGGAGTTTGAAGATGCTGCCTTTGCCTTGAAAAAACC
CGGTGATATTACCGAAACTCCCGTAAAAACTGCTTTCGGTTATCACATCATTAAACTGGAAAAAATTATCCCGGCAAGAC
AAAAAACTTACGAAGAGGTTAAAGAACAGCTGAAAAACTACCTTTTAGAGAAAAAGAAACGCGAAGCTTATAATAAATTC
CTCGAAGACTTAAAGAAAAAAGCCAAGATTGAAACTAAGCTTTCTTTCAAGTAA

Upstream 100 bases:

>100_bases
ATTTTTTCAATTTTAGAAAGGATATTCGGGCAGTTAAGTTGAATATATAAACGGTAAAATTTTTTACAAATTAGTTATTG
TGTAGAGAGGAGAGACAGTA

Downstream 100 bases:

>100_bases
AAACTTAACAAAAAAGTATAAACCCCTCCTTAAGGTAAAATACTAACATTACCAAACCACTTAAGGAGGGAATTTTTATG
AAAGCAACGGGTATTGTGCG

Product: putative peptidyl-prolyl cis-trans isomerase, PpiC-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKKITRVVAVLLTFVLALIVAGCGDYVAKVNGKTISKKDFDRRFAQVQADMKLRGVDLTSTEGQKMLQSLKQQTLDQMIN
EILISEYGKEKKIEPTKDEITNKINEIRAQFPSPQDFEKALKDRNITDKDLQEMVRVQLINDKIYNEVTKGITVSEQEVK
EYYEKHKNEPDFQTPEQRQVRHILIAVNDGNAQNNPHFNINVKRTDAEAKKLAEELIKQIKAGKDFATLAKEKSDDPGVK
ENGGQYTFSRGEMVKEFEDAAFALKKPGDITETPVKTAFGYHIIKLEKIIPARQKTYEEVKEQLKNYLLEKKKREAYNKF
LEDLKKKAKIETKLSFK

Sequences:

>Translated_337_residues
MKKITRVVAVLLTFVLALIVAGCGDYVAKVNGKTISKKDFDRRFAQVQADMKLRGVDLTSTEGQKMLQSLKQQTLDQMIN
EILISEYGKEKKIEPTKDEITNKINEIRAQFPSPQDFEKALKDRNITDKDLQEMVRVQLINDKIYNEVTKGITVSEQEVK
EYYEKHKNEPDFQTPEQRQVRHILIAVNDGNAQNNPHFNINVKRTDAEAKKLAEELIKQIKAGKDFATLAKEKSDDPGVK
ENGGQYTFSRGEMVKEFEDAAFALKKPGDITETPVKTAFGYHIIKLEKIIPARQKTYEEVKEQLKNYLLEKKKREAYNKF
LEDLKKKAKIETKLSFK
>Mature_337_residues
MKKITRVVAVLLTFVLALIVAGCGDYVAKVNGKTISKKDFDRRFAQVQADMKLRGVDLTSTEGQKMLQSLKQQTLDQMIN
EILISEYGKEKKIEPTKDEITNKINEIRAQFPSPQDFEKALKDRNITDKDLQEMVRVQLINDKIYNEVTKGITVSEQEVK
EYYEKHKNEPDFQTPEQRQVRHILIAVNDGNAQNNPHFNINVKRTDAEAKKLAEELIKQIKAGKDFATLAKEKSDDPGVK
ENGGQYTFSRGEMVKEFEDAAFALKKPGDITETPVKTAFGYHIIKLEKIIPARQKTYEEVKEQLKNYLLEKKKREAYNKF
LEDLKKKAKIETKLSFK

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=391, Percent_Identity=25.8312020460358, Blast_Score=104, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 38776; Mature: 38776

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKITRVVAVLLTFVLALIVAGCGDYVAKVNGKTISKKDFDRRFAQVQADMKLRGVDLTS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEECCCCCC
TEGQKMLQSLKQQTLDQMINEILISEYGKEKKIEPTKDEITNKINEIRAQFPSPQDFEKA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
LKDRNITDKDLQEMVRVQLINDKIYNEVTKGITVSEQEVKEYYEKHKNEPDFQTPEQRQV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHH
RHILIAVNDGNAQNNPHFNINVKRTDAEAKKLAEELIKQIKAGKDFATLAKEKSDDPGVK
EEEEEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCC
ENGGQYTFSRGEMVKEFEDAAFALKKPGDITETPVKTAFGYHIIKLEKIIPARQKTYEEV
CCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
KEQLKNYLLEKKKREAYNKFLEDLKKKAKIETKLSFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKITRVVAVLLTFVLALIVAGCGDYVAKVNGKTISKKDFDRRFAQVQADMKLRGVDLTS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEECCCCCC
TEGQKMLQSLKQQTLDQMINEILISEYGKEKKIEPTKDEITNKINEIRAQFPSPQDFEKA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
LKDRNITDKDLQEMVRVQLINDKIYNEVTKGITVSEQEVKEYYEKHKNEPDFQTPEQRQV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHH
RHILIAVNDGNAQNNPHFNINVKRTDAEAKKLAEELIKQIKAGKDFATLAKEKSDDPGVK
EEEEEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCC
ENGGQYTFSRGEMVKEFEDAAFALKKPGDITETPVKTAFGYHIIKLEKIIPARQKTYEEV
CCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
KEQLKNYLLEKKKREAYNKFLEDLKKKAKIETKLSFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]